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  • University of Central Oklahoma CRI-DU-CHAT SYNDROME By James Truby May 3, 2006 BIO 2233 Heredity Paper Assignment CRI-DU-CHAT SYNDROME (CDCS) Cri-du-chat syndrome (CDCS) refers to a unique combination of physical and mental characteristics associated with a loss of genetic material on the distal short arm of the fifth chromosome. (studymode.com)