Tumor Suppressor Protein p53Tumor Suppressor ProteinsGenes, Tumor SuppressorVon Hippel-Lindau Tumor Suppressor ProteinSyndromeTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2MutationGenes, p53Molecular Sequence DataNuclear ProteinsApoptosisNeurofibromin 2Gene Expression Regulation, NeoplasticProtein BindingDNA-Binding ProteinsAdenomatous Polyposis Coli ProteinTranscription FactorsTransfectionCell LineCell CycleCyclin-Dependent Kinase Inhibitor p16Ubiquitin-Protein LigasesGenes, SuppressorTumor Cells, CulturedPTEN PhosphohydrolaseProto-Oncogene ProteinsBase SequenceCyclin-Dependent Kinase Inhibitor p21Amino Acid SequenceCell Cycle ProteinsPromoter Regions, GeneticSignal TransductionCell Transformation, NeoplasticCell ProliferationDNA DamagePhosphorylationNeoplasmsNeoplasm ProteinsCell DivisionLigasesCyclinsTranscription, GeneticE2F Transcription FactorsRepressor ProteinsProteinsRNA, MessengerDown-RegulationTranscriptional ActivationBlotting, WesternProtein Structure, TertiaryTumor Markers, BiologicalGene SilencingE2F1 Transcription FactorBinding SitesCarrier ProteinsSuppressor of Cytokine Signaling ProteinsProtein-Serine-Threonine KinasesDNA MethylationFibroblastsLoss of HeterozygosityReverse Transcriptase Polymerase Chain ReactionTranscription Factor DP1Kidney NeoplasmsHeLa CellsSuppression, GeneticRNA InterferenceGene DeletionGene Expression RegulationCells, CulturedRecombinant Fusion ProteinsOncogene Proteins, ViralRNA, Small InterferingWT1 ProteinsPapillomavirus E7 ProteinsRetinoblastoma-Binding Protein 1Tumor BurdenCell NucleusTrans-ActivatorsTumor Necrosis Factor-alphaRetinoblastoma-Like Protein p107DNA PrimersImmunohistochemistryWilms TumorBreast NeoplasmsProteasome Endopeptidase ComplexMembrane ProteinsDNA, NeoplasmMice, KnockoutPhenotypeCell AgingG1 PhaseHypoxia-Inducible Factor 1, alpha SubunitMice, NudeModels, BiologicalDNAGenes, RetinoblastomaOsteosarcoma