• As with other skin cancers, the risk of developing Merkel cell carcinoma (MCC) can likely be decreased via protection from ultraviolet (UV) light. (medscape.com)
  • More than half of Merkel cell carcinomas (MCCs) occur in the head and neck of elderly people, in areas of actinically damaged skin. (medscape.com)
  • Merkel cell carcinomas (MCCs) usually appear as indurated plaques or violaceous (red or deep purple) solitary and dome-shaped nodules. (medscape.com)
  • Merkel cell carcinomas (MCCs) usually occur in sun-damaged skin. (medscape.com)
  • However, because of the difficulties in distinguishing metastatic oat cell carcinoma from Merkel cell carcinoma (MCC), chest radiography should be performed. (medscape.com)
  • The nonspecific characteristics of Merkel cell carcinoma (MCC) lead to a lengthy differential diagnosis that includes basal cell carcinoma, squamous cell carcinoma, keratoacanthoma, amelanotic melanoma, epidermal cysts, lymphoma, and metastatic carcinoma of the skin. (medscape.com)
  • Subsequent studies involving immunohistochemistry and electron microscopy revealed that these tumors originate from the Merkel cell. (medscape.com)
  • About 3% of patients with Merkel cell carcinoma (MCC) have tumors at several sites. (medscape.com)
  • Merkel cell carcinoma (MCC) is the eponym for primary cutaneous neuroendocrine carcinoma, a dermal neoplasm with cytoplasmic, dense-core neuroendocrine granules and keratin filaments. (medscape.com)
  • Common distribution of Merkel cell carcinoma in the head and neck is shown in the image below. (medscape.com)
  • The glomus type I cells of the carotid body are innervated by the sensory neurons found in the inferior ganglion of the glossopharyngeal nerve. (wikipedia.org)
  • These clear-staining cells at the dermoepidermal junction were near myelinated nerve fibers. (medscape.com)
  • The glomus cells have a high metabolic rate and good blood perfusion and thus are sensitive to changes in arterial blood gas tension. (wikipedia.org)
  • Glomus type I cells are secretory sensory neurons that release neurotransmitters in response to hypoxemia (low pO2), hypercapnia (high pCO2) or acidosis (low pH). (wikipedia.org)
  • In addition to metastasizing to the lymph nodes, Merkel cell carcinoma (MCC) can also spread to the brain, bones, liver, and lungs, thus affecting their function. (medscape.com)
  • The autotransplantation of glomus cells of the carotid body into the striatum - a nucleus in the forebrain, has been investigated as a cell-based therapy for people with Parkinson's disease. (wikipedia.org)
  • Merkel cell carcinoma (MCC) is a deadly disease with a poor likelihood for survival. (medscape.com)
  • They are often found near other lesions of actinically damaged skin, including skin involved with Bowen disease, squamous cell carcinoma , basal cell carcinoma , solar keratoses, or lentigo maligna . (medscape.com)
  • Glomus type II cells are sustentacular cells having a similar supportive function to glial cells. (wikipedia.org)
  • The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). (centralx.com)
  • Glomus type I cells are peripheral chemoreceptors which sense the oxygen, carbon dioxide and pH levels of the blood. (wikipedia.org)