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  • Hypertension
  • In order to examine sympathetic nervous system function in neurocardiological disorders and catecholaminergic effects of dietary manipulations or neuropsychiatric drugs, the protocol calls for evaluations of the kinetics of 3H-norepinephrine or 3H-epinephrine in patients with hypertension, dysautonomias, or disorders thought to involve abnormal catecholaminergic function, and in normotensive normal volunteers. (clinicaltrials.gov)
  • A potential mechanism could be a Y locus that influences chronic sympathetic nervous system activity, which may reinforce neurohumoral factors and structural components of the vessel wall, accelerating the development of hypertension. (ahajournals.org)
  • The renin-angiotensin-aldosterone system (RAAS) plays a key role in the pathology of cardiovascular disease, hypertension, diabetic kidney disease and heart failure. (wikipedia.org)
  • stimulation
  • In the absence of results from leptin infusions, to test for sympathetic stimulation of leptin release, we sought a quantitative naturalistic linkage of sympathetic activity with leptin plasma concentration across a broad range of leptin values in men of widely differing adiposity. (ahajournals.org)
  • 10,13 Thus, there seems to be a 2-way interaction between leptin and the sympathetic nervous system, perhaps constituting a regulatory feedback loop, with leptin acting within the hypothalamus to cause activation of central sympathetic outflow and stimulation of adrenal medullary release of epinephrine 14 and conversely, with the sympathetic nervous system inhibiting leptin release from white adipose tissue. (ahajournals.org)
  • More generally, mydriasis also refers to the natural dilation of pupils, for instance in low light conditions or under sympathetic stimulation. (wikipedia.org)
  • Sympathetic stimulation of the adrenergic receptors causes the contraction of the radial muscle and subsequent dilation of the pupil. (wikipedia.org)
  • ANP is secreted in response to: Stretching of the atrial wall, via Atrial volume receptors Increased Sympathetic stimulation of β-adrenoceptors Increased sodium concentration (hypernatremia), though sodium concentration is not the direct stimulus for increased ANP secretion Endothelin, a potent vasoconstrictor Three types of atrial natriuretic peptide receptors have been identified on which natriuretic peptides act. (wikipedia.org)
  • outflows
  • Apparent spillover and clearance rates are estimated based on the norepinephrine or epinephrine concentration during the infusion and their steady-state specific activities, under resting conditions and in response to physiological or pharmacological manipulations thought to affect sympathetic outflows. (clinicaltrials.gov)
  • cord
  • It originates in the spinal cord and the medulla and controls homeostasis, or the maintenance of the body's systems. (diffen.com)
  • adrenal
  • Leptin administered intravenously, intracerebroventricularly, and into hypothalamic nuclei in rodents has been demonstrated to increase the sympathetic outflow to the kidneys, adipose tissue, and the skeletal muscle vasculature and the neural traffic to the adrenal. (ahajournals.org)
  • aldosterone
  • These drugs inhibit the first and rate-limiting step of the renin-angiotensin-aldosterone system (RAAS), namely the conversion of angiotensinogen to angiotensin I. This leads to a totality in absence of Angiotensin II based on the rationale that renin only acts to inhibit this step unlike Angiotensin Converting Enzyme which is also involved in other biochemical reactions. (wikipedia.org)
  • kidneys
  • In 1896, the Finnish physiologist Robert Tigerstedt and the Swedish physician Per Bergman did an experiment on kidneys and the circulatory system in rabbits. (wikipedia.org)
  • body
  • Both nervous systems work in tandem with each other offering what can seem like a push and pull feel to the body. (winddown.co.uk)
  • The sympathetic nervous system does the pushing whilst the parasympathetic system does the pulling, tensing and calming the body respectively. (winddown.co.uk)
  • The upper part of the body, above the sympathetic chain transection, the body becomes anhidriotic, where the patient is unable to sweat or cool down, which further compromises the body's thermoregulation and can lead to elevated core temperature, overheating and hyperthermia. (wikipedia.org)
  • Below the level of the sympathetic chain interruption, body temperature is significantly lower, creating a stark contrast that can be observed on thermal images. (wikipedia.org)
  • causes
  • Most of the symptoms could be a part of the cluster headache syndrome while other possibilities such as sympathetic overdrive, hormonal/ endocrine/ metabolic issues, neuro-muscular causes, micronutrient deficiencies etc. may need to be considered as well. (medhelp.org)
  • tone
  • Using clinical variables, comparison of the frequency of extrasystoles by day and night, and assessment of the antiarrhythmic effect of beta-blockers, the role of the sympathetic tone in non-ischaemic ventricular arrhythmias may be elucidated. (bmj.com)
  • blood
  • Individuals who suffer from sudden dizzy spells or changes in heart rate and blood pressure may be developing a malfunction in one of these parts of the nervous system . (wisegeek.com)
  • Deterioration of the sympathetic nervous system is a common occurrence as an individual ages, and usually manifests itself as difficulty dealing with stressful situations and a repression of the body's ability to raise blood pressure and heart rate in response to external stimuli. (wisegeek.com)
  • The sympathetic nervous system is involved with regulating blood pressure and pulse rate. (clinicaltrials.gov)
  • MSNA
  • however, responses of the system obtained by microneurographically-recorded MSNA would determine the pathophysiology of the onset and progression of syncope, explaining the treatment effect that could be achieved by the analysis of this mechanism. (frontiersin.org)
  • immune
  • Both immune cells and nerves are involved in pathogenesis, but the mechanisms of prion transfer from the immune to the nervous system are unknown. (uzh.ch)
  • Glucocorticoids also are in affect during times of stress for the sympathoadrenal system, but provide an inhibitory function for the protection of the body from its own immune system. (wikipedia.org)
  • The glucocorticoids work to inhibit reactions produced from the immune system during times of stress that could cause damage within the body. (wikipedia.org)
  • physiology
  • Computational neuroscience (also known as theoretical neuroscience or mathematical neuroscience ) is a branch of neuroscience which employs mathematical models, theoretical analysis and abstractions of the brain to understand the principles that govern the development , structure , physiology and cognitive abilities of the nervous system . (wikipedia.org)
  • Computational
  • The mathematical models formulated in computational neuroscience are useful since they capture the essential features of the biological system at multiple spatial-temporal scales, from membrane currents, proteins, and chemical coupling to network oscillations , columnar and topographic architecture, and learning and memory. (wikipedia.org)
  • The term 'computational neuroscience' was introduced by Eric L. Schwartz , who organized a conference, held in 1985 in Carmel, California , at the request of the Systems Development Foundation to provide a summary of the current status of a field which until that point was referred to by a variety of names, such as neural modeling, brain theory and neural networks. (wikipedia.org)
  • The first graduate educational program in computational neuroscience was organized as the Computational and Neural Systems Ph.D. program at the California Institute of Technology in 1985. (wikipedia.org)
  • glucose
  • Because of this, the sympathoadrenal system plays a large role in maintaining glucose levels, sodium levels, blood pressure, and various other metabolic pathways that couple with bodily responses to the environment. (wikipedia.org)
  • therefore
  • The STQ-77 model is therefore based on Rusalov's model and also on Luria's theory related to three neuroanatomic systems (sensory-informational, programming and energetic) regulating human behavior. (wikipedia.org)
  • Upon
  • And, along with the strong impression made upon Braid by the Medical Gazette's article, there was also the more recent impressions made by Thomas Wakley's exposure of the comprehensive fraud of John Elliotson's subjects, the Okey sisters, [all of which] determined me to consider the whole as a system of collusion or illusion, or of excited imagination, sympathy, or imitation. (wikipedia.org)
  • however
  • However, here's a list of all the books that I've given 5 stars (in my old rating system) and anything between A- and A+ (in my new rating system). (blogspot.com)