AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation ScienceNamed GroupsHealth Care
AmpicillinGram-Positive BacteriaAnti-Bacterial AgentsGram-Negative BacteriaAmpicillin ResistanceBacteriaMicrobial Sensitivity TestsGram-Positive Bacterial InfectionsPhytochemicalsFungiAnti-Infective AgentsAnacardiaceaeGram-Negative Bacterial InfectionsBacterial InfectionsPlant ExtractsEscherichia coliBacteria, AnaerobicSulbactamPenicillinsStaphylococcus aureusColony Count, MicrobialAntibiotic ProphylaxisEnterococcus faecalisBacteremiaDrug Resistance, MicrobialDisk Diffusion Antimicrobial TestsGram-Positive CocciDNA, BacterialDrug Resistance, BacterialPenicillin ResistancePivampicillinBacterial ProteinsGentamicinsRNA, Ribosomal, 16SStaphylococcal InfectionsPseudomonas aeruginosaMolecular Sequence DataChloramphenicolTetracyclinebeta-Lactamasesbeta-LactamsBacillus subtilisHaemophilus influenzaePenicillin GCephalosporinsAminoglycosidesDrug Resistance, Multiple, BacterialStreptomycesEnterobacteriaceaePhylogenyAntifungal AgentsCulture MediaMolecular StructureMagnetic Resonance SpectroscopyTrimethoprimCloxacillinFermentationR FactorsAmoxicillinFecesGentian VioletInfant, NewbornPenicillinaseStreptomycinPenicillanic AcidSulfamethoxazoleCephalexinCephaloridineRetrospective StudiesPhenazinesAntibiotics, AntineoplasticVancomycinErythromycinCiprofloxacinKanamycinKlebsiellaStaphylococcusCarbenicillinEnterococcus
BacteriaOrganismsStrainsSusceptibilityResistantIsolatesBactericidal activityPathogensStaphylococcusKlebsiellaEscherichiaInfections causedCephalosporinsPseudomonasCephalosporin antibioticAntimicrobial resistanceResistance to antibioticsBacterial infectionsVitroSpeciesBeta-lactamaseSemisynthetic antibioticEmpiric antibioticErythromycinPneumoniaeTetracyclinesAcinetobacterInfectionBacillusAztreonamSerratiaMacrolideTrimethoprimRodsIntravenous antibioticsCarbapenemsCommensalBacteriumPenicillinsCell wall synthesisHost defensesEnterococciOralSepsisBroad-spectrum anGroup of antibioticsClasses of antibiotics
Bacteria53
  • Trimethoprim-sulfamethoxazole (TMP-SMX) is effective against many aerobic gram-positive and gram-negative bacteria, but its use in bacterial meningitis is limited to patients with Listeria monocytogenes meningitis who have a penicillin allergy. (medscape.com)
  • Tetracyclines inhibit protein synthesis and, therefore, bacterial growth by binding with 30S and possibly 50S ribosomal subunits of susceptible bacteria. (medscape.com)
  • They are broad-spectrum bacteriostatic antibiotics that are used to treat infections caused by many gram-positive and gram-negative bacteria. (medscape.com)
  • It is effective against most gram-positive and gram-negative bacteria. (medscape.com)
  • Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Ceftriaxone for Injection or other antibacterial drugs in the future.Diarrhea is common problem caused by antibiotics which usually ends when the antibiotic is discontinued. (drugcentral.org)
  • Klebsiellae are nonmotile, rod-shaped, gram-negative bacteria[1] with a prominent polysaccharide capsule. (medscape.com)
  • The combination of amoxycillin with clavulanic acid is sensitive against the strains of bacteria which have developed resistance to β-lactam antibiotics by producing β-lactamase enzymes. (pharmasynth.in)
  • While gram-positive and gram-negative bacteria showed low susceptibility to Ampicillin, Tetracycline and Cotrimoxazole, the GNR were susceptible to Gentamicin and third-generation cephalosporins. (biomedcentral.com)
  • Ceflin 500 mg is indicated for the treatment of infections caused by sensitive Gram-positive and Gram-negative bacteria. (medeasy.health)
  • Ceflin 500 mg is a cephalosporin antibiotic with broad spectrum bactericidal activity against both gram-positive and gram-negative bacteria. (medeasy.health)
  • To reduce the development of drug-resistant bacteria and maintain the effectiveness of amoxicillin and clavulanate potassium tablets, USP and other antibacterial drugs, amoxicillin and clavulanate potassium tablets, USP should be used only to treat infections that are proven or strongly suspected to be caused by susceptible bacteria. (nih.gov)
  • Ceftin is available as a generic drug and is prescribed to treat infections with susceptible bacteria including skin and middle ear infections, tonsillitis , throat infections, laryngitis , bronchitis , pneumonia , urinary tract infections, and gonorrhea . (rxlist.com)
  • These antibiotics are often unnecessary and may cause more problems in the future by destroying the beneficial bacteria that prevent pathogenic bacteria from growing. (chriskresser.com)
  • Long-term use of antibiotics can also lead to antibiotic resistance in strains of bacteria like E. coli in the gut, and a UTI caused by these bacteria will be even more challenging to eliminate and can cause more serious issues like a kidney or bladder infection. (chriskresser.com)
  • Therefore, effective strategies must be implemented to combat antibiotic-resistant bacteria, along with stricter adherence to infection control programmes. (who.int)
  • Por ello, el principal objetivo de este trabajo es aportar información relevante para el control de las enfermedades causadas por Trueperella pyogenes en ganado porcino y rumiantes, especies donde esta bacteria tiene mayor importancia sanitaria y económica. (uco.es)
  • Whole-genome sequencing revealed 5 (0.08%) cases of C. butyricum bacteremia among 6,576 case-patients who had blood cultures positive for any bacteria. (cdc.gov)
  • Following the initial remarkable success of antibiotics, the emergence and spread of human pathogenic bacteria resistant to antibiotics has become a major phenomenon in the past fifty years. (europa.eu)
  • The work package focusing on molecular studies generated new evidence about the changes effected by antibiotic therapy on commensal organisms or opportunistic pathogens in the oropharyngeal, nasal and gastro-intestinal flora and study AMR mechanisms and the dissemination of successful clones of fluoroquinolone-resistant, carbapenem-resistant or extended-spectrum beta-lactamase harboring Gram-negative bacteria, MRSA and fluoroquinolone-resistant viridans streptococci. (europa.eu)
  • The emergence and spread of human pathogenic bacteria resistant to antibiotics has become a major problem in the past fifty years. (europa.eu)
  • Also, SATURN had as mission to improve methodological standards and conduct research to better understand the impact of antibiotic use on acquisition, selection and transmission of antibiotic-resistant bacteria (ARB) in different environments, by combining state-of-the-art analyses of molecular, ecologic and individual patient-level data. (europa.eu)
  • Overall, antimicrobial resistance was infrequent for the Gram-negative and Gram-positive bacteria analyzed. (biomedcentral.com)
  • Piperacillin exerts bactericidal activity by inhibiting septum formation and cell wall synthesis of susceptible bacteria. (popular-pharma.com)
  • In vitro, piperacillin is active against a variety of gram-positive and gram-negative aerobic and anaerobic bacteria. (popular-pharma.com)
  • †These are not --lactamase producing bacteria and, therefore, are susceptible to piperacillin alone. (popular-pharma.com)
  • Staphylococcus aureus, Escherichia coli , and Klebsiella pneumoniae against the extracellular crude protease enzyme produced from the three isolated bacteria and different antibiotics was done. (modernjmicrobiol.com)
  • Resistance to antibiotics occurs because of the changing nature of bacteria that no longer can be killed. (modernjmicrobiol.com)
  • Many infections caused by aerobic and anaerobic gram-negative bacteria resistant to some cephalosporins respond to cefoxitin for injection, USP. (wikidoc.org)
  • Similarly, many infections caused by aerobic and anaerobic bacteria resistant to some penicillin antibiotics (ampicillin, carbenicillin, penicillin G) respond to treatment with cefoxitin for injection, USP. (wikidoc.org)
  • Many infections caused by mixtures of susceptible aerobic and anaerobic bacteria respond to treatment with cefoxitin for injection, USP. (wikidoc.org)
  • Patients who would have met the criteria for HCAP should not be empirically treated with antibiotics to cover MDR bacteria unless they have valid risk factors for acquiring MDR organisms. (medscape.com)
  • Bacteria of the genus Clostridium are characterized because they are gram positive, grow in anaerobic media (with low or no oxygen) and are spore-forming. (veterinariadigital.com)
  • For the active ingredient of Zithromax, Azithromycin, all the gram-positive cocci (except those bacteria which are resistant to erythromycin) are susceptible. (clickmypills.com)
  • During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics. (clickmypills.com)
  • This resistance has spread to strains of E. coli and other gram-negative bacteria (Iroha et al . (scialert.net)
  • Antibiotics are naturally occurring substances produced by a fungus or bacteria. (microbiologyinfo.com)
  • Natural source may include the antibiotic extraction from bacteria, fungi or actinomycetes. (microbiologyinfo.com)
  • For example, glycopeptides and bacitracin are only effective against Gram-positive bacteria, whereas polymixins are usually only effective against Gram negative bacteria. (microbiologyinfo.com)
  • means those antibiotics that stops or inhibits the growth of bacteria that means no multiplication or generation of bacteria but they do not kill bacteria. (microbiologyinfo.com)
  • means those antibiotics that actually kill bacteria by any mechanism depending on the antibiotic used. (microbiologyinfo.com)
  • The current worldwide increase in resistant bacteria and, simultaneously, the downward trend in the development of new antibiotics have serious implications. (medpdfarticles.com)
  • It is a bactericidal antibiotic, meaning it kills bacteria rather than just inhibiting their growth. (air2bhutan.com)
  • It works by killing bacteria and other microorganisms that cause infections. (air2bhutan.com)
  • However, it is important to note that not all urinary tract infections are caused by bacteria that are susceptible to Flagyl. (air2bhutan.com)
  • Bactericidal antibiotics are those that kill bacteria directly, while bacteriostatic antibiotics inhibit bacterial growth and replication without killing them. (air2bhutan.com)
  • 2021). This disease is characterized by inflammation of the mammary gland caused by pathogenic microorganisms, of which 90% are bacteria, specifically those of the coliform group and those of the Streptococcus and Staphylococcus genera (Cheng and Han 2020). (ncsu.edu)
  • Among Gram-negative bacteria (GNB), Enterobacterales ( Enterobacterales ), such as Escherichia coli ( E. coli ) and Klebsiella pneumoniae ( K. pneumoniae ), are the most clinically relevant pathogens in healthcare settings. (frontiersin.org)
  • At its forefront are Gram-negative bacteria, (GNB) such as Enterobacterales ( Enterobacterales ), Pseudomonas aeruginosa , and Acinetobacter baumannii , which have become increasingly resistant to most conventional and broad-spectrum antimicrobial agents, including carbapenems ( Nordmann and Poirel, 2019 ). (frontiersin.org)
  • Intramammary (IMM) ceftiofur treatment is commonly used in dairy farms to prevent mastitis, though its impact on the cattle gut microbiome and selection of antibiotic-resistant bacteria has not been elucidated. (biomedcentral.com)
  • Overall, 90% and 24% of the 278 samples had Gram-negative bacteria with resistance to ampicillin and ceftiofur, respectively. (biomedcentral.com)
  • It is used for the treatment of bacterial infections caused by susceptible microorganisms.This drug is an antibiotic used in the prophylaxis and treatment of serious infections caused by gram-positive bacteria. (whiteswanpharmaceutical.com)
  • Multidrug resistance (MDR) bacteria is defined as non-susceptibility to one or more antimicrobials on three or more antimicrobial classes, while strains that are non-susceptible to all antimicrobials, are classified as extreme drug-resistant strains [ 2 ]. (biomedcentral.com)
  • We aimed to find the most accurate and robust method for the detection of colistin resistance among Gram-negative bacteria by comparing the performance of four methods. (johb.info)
Organisms24
  • Compared with imipenem, meropenem has slightly increased activity against gram-negative organisms and slightly decreased activity against staphylococci and streptococci. (medscape.com)
  • Quinolones have broad activity against gram-positive and gram-negative aerobic organisms. (medscape.com)
  • It interferes with bacterial cell wall synthesis during active replication, causing bactericidal activity against susceptible organisms. (medscape.com)
  • A 6-mo regimen consisting of isoniazid, rifampin, and pyrazinamide given for 2 mo followed by isoniazid and rifampin for 4 mo is the preferred treatment for patients with fully susceptible organisms who adhere to treatment. (cdc.gov)
  • Urine samples were examined for UTI microscopically and by culture, and sensitivity tests were done for the organisms isolated using a range of antibiotics. (who.int)
  • Mixed infections caused by ampicillin-susceptible organisms and β-lactamase-producing organisms which are susceptible to Amoxycillin/Clavulanic acid combination do not require the addition of another antibiotic. (pharmasynth.in)
  • These treatments often worked because many organisms, including many species of mould, naturally produce antibiotics. (wikipedia.org)
  • Gram negative rods (GNR) comprised 39.1% of all isolates with Klebsiella, E . coli and Salmonella being the most common organisms isolated. (biomedcentral.com)
  • Although the organisms are gram positive, many strains give a faint beaded appearance with alternating positive and negative areas. (antimicrobe.org)
  • The Brown-Brenn modification of Gram stain and the Gomori methenamine stain are useful in demonstrating the organisms in histopathologic preparations from tissue ( 20 ). (antimicrobe.org)
  • however, the pathogenic organisms that cause these conditions have shown increased resistance to antibiotics over the past decade. (biomedcentral.com)
  • Infections caused by piperacillin-susceptible organisms, for which piperacillin has been shown to be effective, are also amenable to Megacilin treatment due to its piperacillin content. (popular-pharma.com)
  • The tazobactam component of this combination product does not decrease the activity of the piperacillin component against piperacillin-susceptible organisms. (popular-pharma.com)
  • Therefore, the treatment of mixed infections caused by piperacillin-susceptible organisms and piperacillin-resistant, --lactamase producing organisms susceptible to piperacillin and tazobactam should not require the addition of another antibiotic. (popular-pharma.com)
  • Megacilin is useful as presumptive therapy in the indicated conditions prior to the identification of causative organisms because of its broad spectrum of bactericidal activity against gram-positive and gram-negative aerobic and anaerobic organisms. (popular-pharma.com)
  • Primary inhalation pneumonia develops when these organisms bypass normal respiratory defense mechanisms or when the patient inhales aerobic gram-negative organisms that colonize the upper respiratory tract or respiratory support equipment. (medscape.com)
  • Ceftizoxime is highly resistant to a broad spectrum of beta‐lactamases (penicillinase and cephalosporinase), including Richmond types I, II, III, TEM, and IV, produced by both aerobic and anaerobic gram‐positive and gram‐negative organisms. (nih.gov)
  • It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. (clickmypills.com)
  • Theseare active against both Gram-positive and Gram-negative organisms. (microbiologyinfo.com)
  • This increase poses several problems, including a) the lack of available antimicrobials for therapy of infections caused by VRE, because most VRE are also resistant to multiple other drugs (e.g., aminoglycosides and ampicillin) previously used for the treatment of infections due to these organisms, and b) the possibility that the vancomycin resistance genes present in VRE may be transferred to other gram-positive microorganisms such as Staphylococcus aureus. (cdc.gov)
  • Flagyl is a nitroimidazole antibiotic that exerts its antimicrobial effects by disrupting the DNA of susceptible organisms. (air2bhutan.com)
  • Aztreonam for Injection is indicated for adjunctive therapy to surgery in the management of infections caused by susceptible organisms, including abscesses, infections complicating hollow viscus perforations, cutaneous infections, and infections of serous surfaces. (pfizermedicalinformation.com)
  • In addition to bacterial organisms, oral microorganisms can include fungal, protozoal, and viral species. (medscape.com)
  • Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains. (com.bd)
Strains11
  • The following microorganisms are susceptible, in vitro to Ceflin 500 mg: Gram-positive: Staphylococci (both penicillin sensitive and resistant strains and penicillinase-producing species), Streptococci, Streptococci pyogenes (beta haemolytic), Streptococcus pneumonia. (medeasy.health)
  • Gram-negative: Escherichia coli, Klebsiella spp, Proteus mirabilis, Haemophilus influenza, Shigella spp, Salmonella spp (including Salmonella typhi), Neisseria spp Many strains of E.coli and Staphylococcus aureus that produce the enzyme penicillinase and thus are ampicillin resistant, are susceptible to Ceflin 500 mg which is unaffected by this enzyme. (medeasy.health)
  • CEFTIN tablets are indicated for the treatment of adult patients and pediatric patients (13 years and older) with mild-to-moderate pharyngitis/tonsillitis caused by susceptible strains of Streptococcus pyogenes . (rxlist.com)
  • CEFTIN for oral suspension is indicated for the treatment of pediatric patients aged 3 months to 12 years with mild-to-moderate pharyngitis / tonsillitis caused by susceptible strains of Streptococcus pyogenes . (rxlist.com)
  • CEFTIN tablets are indicated for the treatment of pediatric patients (who can swallow tablets whole) with acute bacterial otitis media caused by susceptible strains of Streptococcus pneumoniae , Haemophilus influenzae (including β-lactamase-producing strains), Moraxella catarrhalis (including β-lactamase-producing strains), or Streptococcus pyogenes . (rxlist.com)
  • CEFTIN for oral suspension is indicated for the treatment of pediatric patients aged 3 months to 12 years with acute bacterial otitis media caused by susceptible strains of Streptococcus pneumoniae , Haemophilus influenzae (including β-lactamase-producing strains), Moraxella catarrhalis (including β-lactamase-producing strains), or Streptococcus pyogenes . (rxlist.com)
  • Nosocomial pneumonia (moderate to severe) caused by piperacillin-resistant, --lactamase producing strains of Staphylococcus aureus and by piperacillin/tazobactam-susceptible Acinetobacter baumanii, Haemophilus influenzae, Klebsiella pneumoniae, and Pseudomonas aeruginosa (Nosocomial pneumonia caused by P. aeruginosa should be treated in combination with an aminoglycoside). (popular-pharma.com)
  • Bacterial strains that are resistant to different antibiotics will multiply then spread so that they become more serious. (modernjmicrobiol.com)
  • Cefoxitin for injection, USP is indicated for the treatment of serious infections caused by susceptible strains of the designated microorganisms in the diseases listed below. (wikidoc.org)
  • It is active concerning a wide range of aerobic and anaerobic gram-positive and aerobic gramnegative microorganisms, including strains producing betalactamase. (clickmypills.com)
  • Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae (including ampicillin-resistant strains) & Klebsiella spp. (com.bd)
Susceptibility11
  • Acinetobacter showed 100.0% susceptibility to Ceftriaxone and Cefotaxime but was resistant (100.0%) to Ampicillin, Tetracycline and Cotrimoxazole. (biomedcentral.com)
  • Klebsiella species showed 8.3% susceptibility to Tetracycline but was resistant to Ampicillin and Cotrimoxazole. (biomedcentral.com)
  • 20.0% susceptibility to Tetracycline and 80.0% susceptible to Gentamicin and Cefuroxime. (biomedcentral.com)
  • Blood culture and antimicrobial susceptibility testing results are usually available between 48-72 hours after the specimen is obtained and therefore initial antimicrobial treatment has been usually empirical with the aim that the most likely pathogens would be susceptible to the chosen drugs [ 5 ]. (biomedcentral.com)
  • Overall, Streptococcus pneumoniae isolates showed reduced susceptibility to erythromycin, but were otherwise susceptible to the other antimicrobials tested. (biomedcentral.com)
  • This study was aimed at determining the urinary bacterial isolates and their susceptibility to selected antibiotics among pregnant women attending antenatal clinics of selected Hospitals in Ilorin, Nigeria. (who.int)
  • Antibiotic susceptibility testing to selected antibiotics was done using Kirby-Bauer disk diffusion technique. (who.int)
  • The Gram-positive isolates showed high susceptibility rate of 100% while the Gram-negative isolates showed moderate susceptibility of 69.2% to nitrofurantoin. (who.int)
  • Five representative ESBL positive isolates, one from each specimen, were investigated for their susceptibility patterns to different gentamicin and floroquinolone combinations. (scialert.net)
  • Following identification and susceptibility testing of the causative organism(s), appropriate antibiotic therapy should be continued. (pfizermedicalinformation.com)
  • This study aims to evaluate the first-line antibiotic susceptibility pattern of toxigenic Corynebacterium diphtheriae isolates. (biomedcentral.com)
Resistant13
  • The antibiotic choice should focus on the most likely pathogens, ranging from anaerobic infections to community-acquired pathogens, to nosocomial or healthcare-associated pathogens, to resistant gram-positive pneumonias. (medscape.com)
  • Antimicrobial resistant microorganisms are found in people, animals and the environment and can spread globally. (who.int)
  • This increase poses important problems, including a) the lack of available antimicrobial therapy for VRE infections, because most VRE are also resistant to drugs previously used to treat such infections (e.g., aminoglycosides and ampicillin), and b) the possibility that the vancomycin-resistant genes present in VRE can be transferred to other gram-positive microorganisms (e.g. (cdc.gov)
  • Gram negative isolates showed high resistance rate of 73.1% to ampicillin and 65.4% to amoxicillin-clavulanic acid while Gram-positive isolates showed high resistant rate of 94.1% to penicillin. (who.int)
  • The isolation of bacterial pathogens resistant to the commonly prescribed antibiotics from pregnant women symptomatic and asymptomatic for UTI calls for early screening of all pregnant women for UTI during antenatal care service delivery. (who.int)
  • Cefizox ® (ceftizoxime for injection, USP) is a sterile, semisynthetic, broad‐spectrum, beta‐lactamase resistant cephalosporin antibiotic for parenteral (IV, IM) administration. (nih.gov)
  • Five P. multocida isolates (3.6%), all obtained from NSW in 2019, exhibited dual resistance to macrolides and tetracycline, and a further two Queensland isolates from 2019 (1.4%) exhibited a multidrug-resistant phenotype to ampicillin/penicillin, tetracycline, and tilmicosin. (edu.au)
  • Illumina whole genome sequencing identified the genes msr(E) and mph(E)encoding macrolide resistance, tet(R)-tet(H) or tet(Y) encoding tetracycline resistance, and blaROB-1 encoding ampicillin/penicillin resistance in all isolates exhibiting a corresponding resistant phenotype. (edu.au)
  • The exception was the tilmicosin-resistant, tulathromycin/gamithromycin-susceptible phenotype identified in two Queensland isolates, the genetic basis of which could not be determined. (edu.au)
  • Enterobacterales isolates that are concomitant ESBL producers and are carbapenem resistant have been increasingly reported and demonstrate alarmingly increased antibiotic resistance patterns compared with ESBL Enterobacterales . (frontiersin.org)
  • However, the HCAP classification and the scores proposed in literature to identify resistant pathogens in CAP are overly sensitive, leading to inappropriately broad-spectrum antibiotic use. (mdpi.com)
  • In the last two decades multi drug resistant microorganisms (both hospital- and community-acquired) challenged the scientific groups into developing new antimicrobial compounds that can provide safety in use according to the new regulation, good efficacy patterns, and low resistance profile. (biomedcentral.com)
  • Of these compounds some are already approved by official agencies, some are still in study, but the need of new antibiotics still does not cover the increasing prevalence of antibiotic-resistant bacterial infections. (biomedcentral.com)
Isolates4
  • Gram positive cocci (GPC) were the predominant isolates with Coagulase positive (32.2%) and Coagulase-negative (28.7%) Staphylococci accounting for 60.9% of the total isolates. (biomedcentral.com)
  • 182 (50.8%) isolates were Gram-positive. (biomedcentral.com)
  • Resistance to ampicillin and TMP/SMZ was observed in several of the H. influenzae isolates. (biomedcentral.com)
  • The present study evaluated the antimicrobial effect of different combinations of gentamicin and floroquinolones (ciprofloxacin, ofloxacin, perfloxacin and gatifloxacin) against extended spectrum beta lactamase (ESBL) positive E. coli isolates using checkerboard method. (scialert.net)
Bactericidal activity4
  • A broad-spectrum carbapenem antibiotic, meropenem inhibits cell wall synthesis and has bactericidal activity. (medscape.com)
  • Penicillin G interferes with the synthesis of cell wall mucopeptide during active multiplication, resulting in bactericidal activity against susceptible microorganisms. (medscape.com)
  • Formulations of amoxicillin contain amoxicillin, a semisynthetic antibiotic, an analog of ampicillin, with a broad spectrum of bactericidal activity against many gram-positive and gram-negative microorganisms. (prescriptiondrugs.com)
  • Ceftiofur has bactericidal activity against both Gram-negative and Gram-positive bacterial populations, low toxicity potential, and efficient penetration of most body fluids. (biomedcentral.com)
Pathogens7
  • 20140020001824), and the Project "Multiomic approaches to the study of antibiotic resistance in Gram-positive pathogens ", within the XXII Own Program for the of Research Promotion, Modality 4.2. (uco.es)
  • Because aerobic gram-negative bacilli (eg, Pseudomonas aeruginosa) are the major pathogens associated with HAP, the pathophysiology of nosocomial pneumonia relates to the destructive effect on lung tissue. (medscape.com)
  • Aerobic gram-negative pathogens may be divided into 2 categories. (medscape.com)
  • Aztreonam for Injection is effective against most of the commonly encountered Gram-negative aerobic pathogens seen in general surgery. (pfizermedicalinformation.com)
  • Concurrent initial therapy with other antimicrobial agents and aztreonam for injection is recommended before the causative organism(s) is known in seriously ill patients who are also at risk of having an infection due to Gram-positive aerobic pathogens. (pfizermedicalinformation.com)
  • The microorganisms mainly involved in the resistance process, so called the ESKAPE pathogens ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, and enterobacteriaceae ) were the main targets. (biomedcentral.com)
  • Numerous agencies and professional societies have tried to draw attention to the lack of new antibiotics, especially for MDR Gram-negative pathogens. (biomedcentral.com)
Staphylococcus2
Klebsiella2
  • Escherichia coli and Klebsiella were 80.0% and 91.0% susceptible to Ceftriaxone and Cefotaxime respectively. (biomedcentral.com)
  • Coagulase Negative, Coagulase Positive Staphylococci, Salmonella and Klebsiella were the aetiological agents of bloodstream infection among children at TTH. (biomedcentral.com)
Escherichia1
  • Escherichia coli was the most frequently isolated organism (41.5%), and it was highly susceptible to chloram- phenicol, ciprofloxacin, ceftizoxime and amikacin. (who.int)
Infections caused6
  • Infections caused by Amoxycillin sensitive microorganisms. (pharmasynth.in)
  • However, recent reports of outbreaks and endemic infections caused by enterococci, including VRE, have indicated that patient-to-patient transmission of the microorganisms can occur either through direct contact or through indirect contact via a) the hands of personnel or b) contaminated patient-care equipment or environmental surfaces. (cdc.gov)
  • Vancomycin resistance in enterococci has coincided with the increasing incidence of high-level enterococcal resistance to penicillin and aminoglycosides, thus presenting a challenge for physicians who treat patients who have infections caused by these microorganisms (1,4). (cdc.gov)
  • In randomized comparative studies, Cefoxitin for injection, USP and cephalothin were comparably safe and effective in the management of infections caused by gram-positive cocci and gram-negative rods susceptible to the cephalosporins. (wikidoc.org)
  • It is prescribed at diagnosing of bacterial infections caused by microorganisms, sensitive to drug: infections of upper respiratory tracts, bacterial infections of skin and soft tissues, infections of urogenital tract, sepsis, infection pelvic organs. (clickmypills.com)
  • Used in the treatment of infections caused by microorganisms susceptible to cefalexin: ENT organs and respiratory tract, genitourinary system, skin and soft tissues, bone tissue and joints. (clickmypills.com)
Cephalosporins5
  • Medaclor (Cefaclor,) is a semisynthetic cephalosporin antibiotic for oral administration In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. (medico-labs.com)
  • 5-Antibiotics, including cephalosporins, should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis. (medico-labs.com)
  • In the mid 1960s, the penicillin antibiotics was joined by the cephalosporins, and towards the end of the 20th century by carbapenems and monobactams. (microbiologyinfo.com)
  • ESBL-producing Enterobacterales from the GCC region show high levels of resistance to ampicillin, aztreonam, third-/fourth-generation cephalosporins, fluoroquinolones, and trimethoprim-sulfamethoxazole. (frontiersin.org)
  • In the U.S, less than 1% of all antibiotics used in livestock correspond to cephalosporins, with most use (80%) occurring in cattle [ 3 ]. (biomedcentral.com)
Pseudomonas1
  • Certain antibiotics (eg, cefoxitin, imipenem) may induce high levels of beta-lactamase in vitro in some Gram-negative aerobes such as Enterobacter and Pseudomonas species, resulting in antagonism to many beta-lactam antibiotics including aztreonam. (pfizermedicalinformation.com)
Cephalosporin antibiotic1
  • Ceftin ( cefuroxime ) is a cephalosporin antibiotic . (rxlist.com)
Antimicrobial resistance2
  • Thus, the main global objectives of SATURN were to study the impact of antibiotic exposure on antimicrobial resistance (AMR) and to define strategies to improve knowledge on antibiotic selection pressure and judicious antibiotic use. (europa.eu)
  • In Enterobacterales , the prime antimicrobial resistance mechanism against β-lactam antibiotics is mainly the production of β-lactamases, particularly extended-spectrum β-lactamases (ESBLs). (frontiersin.org)
Resistance to antibiotics5
  • Many of them aimed medical practice, emphasizing issues regarding adverse side effects, increasing and dissemination of bacterial resistance to antibiotics, pattern of medicine prescription and influence of medicine advertising on prescription 3 . (bvsalud.org)
  • Bacterial resistance to antibiotics is growing up day by day in both community and hospital setting, with a significant impact on the mortality and morbidity rates and the financial burden that is associated. (biomedcentral.com)
  • Bacterial resistance to antibiotics is growing up day by day in both community and hospital setting, increasing mortality and morbidity [ 1 ]. (biomedcentral.com)
  • The search for new antimicrobial compounds able to overcome the global issue of microbial resistance to antibiotics is a priority worldwide. (springeropen.com)
  • Microbial resistance to antibiotics is recognized as a major public health issue that urges rapid and effective resolution (Alanis 2005 ). (springeropen.com)
Bacterial infections2
Vitro4
  • Microbiological tests have reported greater in-vitro activity of amoxycillin against S. pneumoniae than does ampicillin or penicillin. (pharmasynth.in)
  • Por otra parte, la información que se dispone actualmente sobre el comportamiento de T. pyogenes frente a los antimicrobianos utilizados en ganadería es limitada, y hasta hace tres años, no existían normas publicadas para la realización de las pruebas de sensibilidad in vitro para esta especie, que permitieran comparar los resultados entre estudios. (uco.es)
  • The vanA gene, which is frequently plasmid-borne and confers high-level resistance to vancomycin, can be transferred in vitro from enterococci to a variety of gram-positive microorganisms,[18,19] including S. aureus[20]. (cdc.gov)
  • These in vitro findings suggest that such beta-lactamase inducing antibiotics not be used concurrently with aztreonam. (pfizermedicalinformation.com)
Species2
  • Using KEGG database it was discovered that sequenced species have potential to produce antibiotics such as fosfomycin and streptomycin. (actascientific.com)
  • They have limited activity and are primarily only useful against particular species of microorganisms either Gram positive or Gram negative. (microbiologyinfo.com)
Beta-lactamase3
  • This is a drug combination of a beta-lactamase inhibitor with ampicillin. (medscape.com)
  • This protects the activity of the beta-lactam antibiotics given in conjunction with clavulanic acid from beta-lactamase catalysis. (pharmasynth.in)
  • It has similar structure to beta lactam antibiotics which binds irreversibly to beta-lactamase enzymes and inactivates them. (com.bd)
Semisynthetic antibiotic1
  • Clindamycin is a semisynthetic antibiotic produced by 7(S)-chloro-substitution of 7(R)-hydroxyl group of the parent compound lincomycin. (medscape.com)
Empiric antibiotic2
  • Begin empiric antibiotic coverage according to age and presence of overriding physical conditions. (medscape.com)
  • [2] The empiric antibiotic for Gram-negative sepsis is either carbapenems or Piperacillin-Tazobactam. (jacmjournal.org)
Erythromycin1
  • The sensitivity test by E-test®of the five antibiotics (penicillin, oxacillin, erythromycin, azithromycin, and clarithromycin) was done to determine the minimum inhibitory concentration (MIC). (biomedcentral.com)
Pneumoniae1
Tetracyclines1
  • Doxycycline is a semi-synthetic antibiotic of a broad spectrum of tetracyclines. (clickmypills.com)
Acinetobacter1
  • The most common microorganisms were Acinetobacter spp. (who.int)
Infection5
  • Additionally to analgesics, anti-inflammatories and antibiotics, used to combat pain, inflammation and infection, respectively, dentists can still make use of anxiolytics, in cases of patients very fearful to endodontic treatment. (bvsalud.org)
  • According to Siqueira Júnior (1997) 20 , in approximately 60% of infection human cases, the host defenses themselves account for the process cure, without antibiotics. (bvsalud.org)
  • Des prélèvements d'urine ont fait l'objet d'un examen microbi- ologique (examen au microscope et mise en culture) à la recherche d'une infection urinaire, et des tests de sensibilité ont été réalisés avec divers antibiotiques pour les germes isolés. (who.int)
  • Furthermore, antibiotics do very little to prevent the infection from happening in the first place. (chriskresser.com)
  • Infective endocarditis is an infection of the endocardial surface of the heart including infections of the large thoracic vessels and intracardiac foreign bodies characterized by the presence of vegetation which is a nidus for microorganism invasion. (mims.com)
Bacillus1
  • Clostridium butyricum is a strictly anaerobic, gram-positive, spore-forming bacillus named for its capacity to produce high amounts of butyric acid. (cdc.gov)
Aztreonam1
  • and B. licheniformis recorded high sensitivity (71%) against most antibiotics, in addition, B. subtilis showed resistance to Aztreonam only. (modernjmicrobiol.com)
Serratia1
  • [ 9 ] Alternatively, other non-necrotizing gram-negative bacilli (eg, Serratia marcescens) may be responsible for nosocomial pneumonia. (medscape.com)
Macrolide3
  • It is a good alternative antibiotic for patients allergic to or intolerant of the macrolide class. (medscape.com)
  • Antibiotic-azalide, a representative of a new subgroup of macrolide antibiotics. (clickmypills.com)
  • Penicillin and macrolide are groups of empirical antibiotics used to eradicate toxigenic C. diphtheriae based on the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC) guidelines for the treatment of diphtheria [ 9 , 10 ]. (biomedcentral.com)
Trimethoprim1
  • El documento VET06 establece puntos de corte para la categoría susceptible para la penicilina, ampicilina, eritromicina y trimethoprim/sulfametoxazol, pero no para otros antimicrobianos de uso frecuente en ganadería. (uco.es)
Rods1
  • Nocardia microorganisms are filamentous rods that show right-angled branching both in culture and in tissues. (antimicrobe.org)
Intravenous antibiotics2
  • Initiate therapy with intravenous antibiotics and transition to oral agents or equivalent agents based on clinical response. (medscape.com)
  • Management includes intravenous antibiotics for infectious cases, addressing the underlying etiology for noninfectious cases, and surgical repair when necessary. (lecturio.com)
Carbapenems2
  • Increasing antibiotic resistance, particularly among carbapenems, has made the management of sepsis very challenging. (jacmjournal.org)
  • With increasing antibiotic resistance, particularly the carbapenems, the management of sepsis is challenging. (jacmjournal.org)
Commensal1
  • Moreover, several commensal microorganisms have been increasingly associated to opportunistic microbial infections. (springeropen.com)
Bacterium1
  • Doctors typically use antibiotics to treat UTIs, and the type and duration depend on your health condition and the type of bacterium found in your urine. (chriskresser.com)
Penicillins2
  • The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. (wikipedia.org)
  • For 20 years after their introduction, the penicillins were the only category of β - lactam antibiotics. (microbiologyinfo.com)
Cell wall synthesis1
  • Amoxycillin, a beta-lactam antibiotic, inhibits bacterial cell wall synthesis by binding to one or more penicillin-binding proteins (PBPs). (pharmasynth.in)
Host defenses2
  • If fever, swelling, prostration, lymphadenitis, and acute dentoalveolar abscess is present, indicating that the infectious process is not properly controlled by the host defenses, antibiotics are required. (bvsalud.org)
  • The development of hospital-acquired pneumonia (HAP) represents an imbalance between normal host defenses and the ability of microorganisms to colonize and then invade the lower respiratory tract. (medscape.com)
Enterococci1
  • Because enterococci are part of the normal flora of the gastrointestinal and female genital tracts, most infections with these microorganisms have been attributed to the patient's endogenous flora (15). (cdc.gov)
Oral3
  • Amoxil - is a semi-synthetic aminopenicillin antibiotic of broad spectrum effects for oral administration. (clickmypills.com)
  • Methods The INTENSE study is a multicentre, open-label, randomised, pragmatic, phase-IV clinical trial to demonstrate the non-inferiority of a 7-day vs 14-day course for the treatment of uncomplicated enterococcal bacteraemia and incorporating the early switching to oral antibiotics when feasible. (bmj.com)
  • Oral microorganisms may also enter the deeper tissue after trauma or surgery, which contributes to the disease process, particularly when they cause BE. (medscape.com)
Sepsis2
  • The significant risk factors for sepsis with CRO in the present study were chronic liver disease, increased duration of hospital stay and exposure to antibiotics. (jacmjournal.org)
  • Being a reserve drug, we recommend Colistin to be restrictively used as an empiric therapy only in those patients who developed sepsis after hospital stay, who had prolonged antibiotic exposure as well as in patients with chronic liver disease. (jacmjournal.org)
Broad-spectrum an1
Group of antibiotics1
  • Medaclor is contraindicated in patients with known allergy to the cephalosporin group of antibiotics. (medico-labs.com)
Classes of antibiotics4
  • Investigations have shown that ESBL enzymes also confer resistance to other classes of antibiotics (Fashae et al . (scialert.net)
  • In this review we made an evaluation of present data regarding the new classes and the new molecules from already existing classes of antibiotics and the ongoing trends in antimicrobial development. (biomedcentral.com)
  • Recently, IDSA supported a proGram, called " the ′10 × ′20′ initiative ", to develop ten new systemic antibacterial drugs within 2020 through the discovery of new drug classes, as well as to find possible new molecules from already existing classes of antibiotics [ 7 ]. (biomedcentral.com)
  • In this review the new drugs belonging to both old and new classes of antibiotics will be analysed and discussed (Table 1 ). (biomedcentral.com)