Survival function age factors. Medical search. Frequent questions

Indeed, if there are many possible prognostic factors there will almost certainly be differences between the groups despite the use of random allocation. (bmj.com)
In a small clinical trial a large treatment effect is being sought, but a large difference in one or more of the prognostic factors can occur purely by chance. (bmj.com)
Survival analysis revealed that IL8, IL2Ra (CD25) and PF4 were independent determinants of a more negative prognosis in mesothelioma patients, independent of other known prognostic factors. (iospress.com)
General prognostic indicators that have been published include age, sex, histology, and performance status, with refinements accounting for weight loss, haemoglobin and albumin levels also being reported [ 6 ]. (iospress.com)
Prognostic factors for survival in the overall cohort (IPF and CTD-ILD) and in the CTD-ILD group were identified with univariate and multivariate Cox regression models. (jrheum.org)

After adjustment for age and left ventricular ejection fraction (LVEF), the hazard ratio for all-cause mortality was a significant 0.29 for those taking metformin compared with those not taking metformin. (medscape.com)

Survivorship curves can be constructed for a given cohort (a group of individuals of roughly the same age) based on a life table. (wikipedia.org)
Therefore, in this large single-center cohort of patients, we sought to reveal the prevalence of CKD before and after RNU and to develop a nomogram to predict ineligibility for AC, which would help to accurately predict postoperative renal function and thus provide more optimal and personalized risk-based therapy options. (hindawi.com)
In untreated, seropositive, Caucasian, college-educated men, with a mean age of 55, the prevalence of frailty, 3.4%, was similar to that of HIV seronegative males older than 65 from the same cohort [73]. (natap.org)
However, there is a wide range in survival time with 5 to 10% of the cohort surviving for 5 years [ 5 ]. (iospress.com)
The objectives of the present study were to assess survival and to identify predictors of mortality in COVID-19 patients at Kinshasa University Hospital.Methods: a retrospective cohort study was conducted, 141 COVID-19 patients admitted at the Kinshasa University Hospital from March 23 to June 15, 2020 were included in the study. (bvsalud.org)
ABSTRACT A retrospective cohort study was conducted to determine the 5-year survival and prog- nostic factors for survival for 407 oropharyngeal cancer cases registered in the 3 main hospitals in Alexandria, Egypt, from 1996-2000. (who.int)

Our regression analyses confirm that these factors play strong quantitative roles in the formation of subjective survival beliefs. (netspar.nl)
A Cox regression model was used to compare survival in patients with and without a fracture at MM diagnosis and another Cox model was used with fracture as a time-dependent variable to assess the effect of fracture on survival after MM diagnosis. (haematologica.org)
Associations with survival were evaluated by Cox proportional hazards regression methods. (iospress.com)
However, Cox proportional regression showed that tumour stage was the only factor that significantly influenced survival analysis after controlling for other factors. (who.int)
Survival analysis was conducted using Kaplan-Meier curves, and multivariate Cox regression analysis. (who.int)
Multivariable linear regression models were used to assess risk factors associated with arterial stiffness and HRV at follow-up. (cdc.gov)

Previous studies have identified many immune pathways which are consistently altered in humans and model organisms as they age. (biomedcentral.com)

We retrospectively studied clinical signs and symptoms and risk factors for fatal outcome among 31 Ebola virus-positive patients admitted to the Ebola Treatment Center in Moyamba District, Sierra Leone. (cdc.gov)
These risk factors for death could be used to identify patients in need of more intensive medical support. (cdc.gov)
We calculated prevalence, standard errors (SEs), and 95% confidence intervals (CIs) and ranked states according to the prevalence of each risk factor indicator. (cdc.gov)
In general the age effect is larger, but for some conditions, for example knee disease in plumbers, work is the dominant risk factor. (cdc.gov)
300 mg/g were 1.41 (95% confidence interval [CI] 1.01-1.98), 2.10 (95% CI 1.48-2.99), and 2.70 (95% CI 1.58-4.61), respectively, in analyses adjusted for traditional stroke risk factors and eGFR. (nih.gov)
In contrast, the hazard ratios among white subjects were only modestly elevated and not statistically significant after adjustment for established stroke risk factors. (nih.gov)
60 mL/min/1.73 m(2) was not associated with incident stroke in black or white participants after adjustment for established stroke risk factors. (nih.gov)
Current research of risk factors potentially associated with successful aging faces the difficulty of taking into consideration two distinct outcome measures: survival and functioning. (bmj.com)
Brain-derived neurotrophic factor may work as a potential biomarker to predict the risk of PSD among stroke survivors. (frontiersin.org)
The aim of this study is to investigate the prevalence of musculoskeletal and cognitive diseases and their risk factors and also to assess their associations during future follow-ups. (bmj.com)
The study findings will show the prevalence of musculoskeletal disease, cognitive impairment and their risk factors in an elderly population. (bmj.com)
6-8 Tuberculosis and depressive disorder share many risk factors (eg, poverty and homelessness) 6 that could partially explain the high prevalence of comorbid depressive disorder in TB patients. (psychiatrist.com)
Here's a 5 second refresher course on the lifestyle factors that increase their risk: high Body Mass Index, poor diet, smoking, alcohol, sedentary lifestyle and stress. (nutritionvista.com)
Its really so simple guys -JUST 30 -40 minutes a day of regular physical activity contributes to health by reducing the heart rate, decreasing the risk for cardiovascular disease, and reducing the amount of bone loss that is associated with age and osteoporosis. (nutritionvista.com)
The study also included 52 age- and sex-matched, healthy controls with no history of cardiac disease or major risk factors. (medscape.com)
Modifiable risk factors for frailty including neurocognitive impairment, obesity, smoking, choice of initial cART (with NNRTI [non-nucleoside reverse transcriptase inhibitor]-based cART increasing risk of frailty), and level of education. (natap.org)
Risk factors included older age and non-Hispanic black ethnicity. (natap.org)
9 8 This imbalance, along with decreased bone mineral density and treatment-related factors such as treatment with glucocorticoids, can lead to fractures in MM. 11 10 5 In a population-based retrospective study, MM patients were found to have a 9-fold increase in risk of fractures after MM diagnosis, as compared to expected fracture rates in the population. (haematologica.org)
The tables in the Risk Factor Overview summarize the results from a number of studies of the association between diabetes mellitus and Alzheimer disease (AD). (alzrisk.org)
Hyperglycemia is also one part of the "metabolic syndrome," a cluster of co-occurring factors which increase the risk of cardiovascular disease and stroke. (alzrisk.org)
Given the established link between vascular disease and the pathogenesis and/or progression of dementia and AD [1, 2], the co-occurrence of diabetes with these factors likely contributes to a relationship between diabetes and dementia risk. (alzrisk.org)
However, these studies did not evaluate disease risk and survival in the same population and, therefore, were not able to examine the interplay between indicators of robustness and resilience, which is the focus of this study. (aging-us.com)
Background and objectivesWith expansion of the pool of kidney grafts, through the use of higher-risk donors, and increased attention to donor management strategies, the 1-year graft survival rate is subject to change. (ox.ac.uk)
It is, therefore, useful to elucidate 1-year graft survival rates by dissecting the characteristics of the low-risk and high-risk kidney transplant cases. (ox.ac.uk)
95% CI, 1.46 to 2.47) as risk factors for 1-year graft loss. (ox.ac.uk)
The effect of each risk factor is small. (ox.ac.uk)
However, it is established that Fontan patients have poor exercise capacity, associated with a greater risk of morbidity and mortality, in addition to decreased muscle mass, abnormal muscle function, and endothelial dysfunction contributing to disease progression. (stanford.edu)
Overhydration and low hemoglobin levels were independent risk factors for LVH. (homedialysis.org)
In data from 10 studies of 12,595 people, risk factors for EPS included younger age for starting PD, higher transport rates, longer PD duration, longer peritonitis duration, and history of glomerulonephritis. (homedialysis.org)
Although the cause of IPF is unknown, risk factors include a history of smoking, family history, and genetic predispositions. (medscape.com)
Methods: A systematic review to determine risk factors and interventions associated with mortality/survival in adult patients admitted to an intensive care unit (ICU) with confirmed COVID-19/SARS-CoV-2 infection. (bvsalud.org)
Introduction: since the 1st case of coronavirus disease 2019 (COVID-19) in Kinshasa on March 10th 2020, mortality risk factors have not yet been reported. (bvsalud.org)
Introduction: Several studies have shown an increased risk of cancer after non melanoma skin cancers (NMSC) but the individual risk factors underlying this risk have not been elucidated, especially in relation to sun exposure and skin sensitivity to sunlight. (cdc.gov)
Purpose: The aim of this study was to examine the individual risk factors associated with the development of subsequent cancers after non melanoma skin cancer. (cdc.gov)
Methods: Participants in the population-based New Hampshire Skin Cancer Study provided detailed risk factor data, and subsequent cancers were identified via linkage with the state cancer registry. (cdc.gov)
A Cox proportional hazard model was used to estimate risk of subsequent malignancies in NMSC patients versus controls and to assess the potential confounding effects of multiple risk factors on this risk. (cdc.gov)
Conclusions: Our population-based study indicates an increased cancer risk after NMSC that cannot be fully explained by known cancer risk factors. (cdc.gov)
The two major types of NMSC, basal cell (BCC) and squamous risk factor data [8,9,24,30]. (cdc.gov)
In addition, environmental factors such as smoking or exposure to radiation increase an individual's risk of developing acute myeloid leukemia. (medlineplus.gov)
OBJECTIVE: We compared arterial stiffness and heart rate variability (HRV) over time by diabetes type and determined the risk factors associated with worsening arterial stiffness and HRV in young adults with youth-onset diabetes. (cdc.gov)
Risk factors associated with worse arterial stiffness and HRV at follow-up in both types of diabetes included higher blood pressure, hemoglobin A1c, waist circumference and triglycerides overtime and longer diabetes duration. (cdc.gov)
The risk factor profile documents potentially modifiable pathways to prevent or limit cardiovascular complications in young adults with youth-onset diabetes. (cdc.gov)
Factors limiting the usefulness of anergy skin testing include problems with standardization and reproducibility, the low risk for TB associated with a diagnosis of anergy, and the lack of apparent benefit of preventive therapy for groups of anergic HIV-infected persons. (cdc.gov)

The prevalence of smoking among US adults aged 65 years or older was 9.6% ( Table 1 ). (cdc.gov)
the relationship between aging and increasing musculoskeletal symptom prevalence was persistent across all trades. (cdc.gov)
PANINI researchers have produced extensive reviews of the scientific literature on relevant topics such as the occurrence of frailty in hospital patients, sedentary behaviour prevalence, sedentary behaviour and physical function, dietary pattern impact on cognition and brain imaging measures, and the impact of interventions to reduce sedentary time. (europa.eu)

Finally, PANINI has developed and tested nutritional and physical activity interventions in a range of settings and older adult populations in terms of their impact on cognitive, psychological, social, and physical function measures, leading to conclusions regarding the feasibility of such interventions as well as the impact of intervention adherence. (europa.eu)
Besides PSD is often associated with symptoms of cognitive impairment such as agnosia and memory changes, which may be mistakenly regarded as the consequences of stroke or old age, so it was estimated that approximately 50-80% of PSD cases were underdiagnosed ( 2 , 17 ). (frontiersin.org)
Our estimates suggest that implied measures for cognitive weakness increase and relative optimism decrease with age. (netspar.nl)
Our main finding is that cognitive weakness rather than optimism is an increasingly important contributor to the well-documented overestimation of survival chances in old age. (netspar.nl)
Summary: Alzheimer's disease(AD) is a progressive, irreversible neurodegenerative disease that destroys memory and cognitive function. (atsbio.com)
The team recruited 65 older adults with normal cognitive function for the study. (naturalnews.com)

Previous studies either used successful aging measures restricted to survivors or presented more than one outcome measure to handle the dual outcome. (bmj.com)
The primary objective of randomisation is to ensure that all other factors that might influence the outcome will be equally represented in the two groups, leaving the treatment under test as the only dissimilarity. (bmj.com)
When published a randomised trial typically includes a table listing all the prior factors known actually or possibly to influence outcome. (bmj.com)
The average age and its distribution in each group and the proportion of men and women usually head the list, followed by other likely determinants of outcome. (bmj.com)
It would then be impossible to attribute a better outcome in the other group to the beneficial effects of treatment since poor left ventricular function and age at outset are major determinants of survival in any longitudinal study of heart disease, and women with diabetes, as a group, are likely to do worse. (bmj.com)
Are pain and function better measures of outcome than revision rates after TKR in the younger patient? (ox.ac.uk)
Revision is the gold standard outcome measurement for survival analyses of orthopaedic implants but reliance on revision as an endpoint has been recently questioned. (ox.ac.uk)
This study, that assesses long-term outcome in a specific group of patients who had undergone total knee replacement (TKR) for osteoarthritis, highlights the main problems facing modern survival analyses. (ox.ac.uk)
Minimum 12-year survival and outcome data were reviewed for a series of sixty patients under the age of 60 years (mean age 55.4 years) who underwent total knee replacement (TKR) for osteoarthritis. (ox.ac.uk)
Survival based on revision alone provides an acceptable but inaccurate impression of outcome in younger TKR patients (under 60 years). (ox.ac.uk)
We sought to determine the effect of juvenile plasma-derived factors on the outcome following hemorrhagic shock injury in aged mice. (elsevierpure.com)

Thirty-seven different tissues in the human body utilize vitamin D and need it for adequate functioning. (yahoo.com)
It's created in the skin, although 'the amount of sunlight needed to synthesize adequate amounts of vitamin D varies, depending upon the person's age, skin color, sun exposure and underlying medical problems,' says Shamim Shakibai, an internal medicine physician at Marina Del Rey Hospital in Marina del Rey, California. (yahoo.com)
A year later, both groups had adequate PD and similar peritoneal transport, residual kidney function, blood pressure control, anemia management, and correction of bone minerals. (homedialysis.org)

Cite this: Metformin Ups Myocardial Perfusion and Survival in T2D - Medscape - May 09, 2023. (medscape.com)

The results confirm previous reports that metformin treatment of adults with type 2 diabetes significantly associates with improved overall survival. (medscape.com)
5 To prevent skeletal-related events, treatment with bisphosphonates is recommended for most patients with MM, and treatment with zoledronic acid has been reported to improve overall survival in MM patients. (haematologica.org)
Outcomes included cumulative incidence of common health disorders from age 65 and overall survival. (aging-us.com)

Recent research has shown that pieces of fetal nigral tissue placed in the striatum of 6-OHDA lesioned rats offer greater cell survival and predictability of graft function (in comparison to dissociated nigral cells) in the animal model of Parkinson's disease [ 20 ]. (hindawi.com)

A Swedish construction worker 55-59 years old was more than twice as likely to have shoulder problems as a similarly aged office worker, but 25% less likely to be symptomatic when both were 25-29 years old. (cdc.gov)
In the Finnish studies, a clearly identifiable middle-aged subgroup declined rapidly in subsequent years, whereas a group maintaining high function through the sixth decade was also recognizable. (cdc.gov)
Associations of urinary albumin to creatinine ratio (ACR) and eGFR with incident stroke were examined in 25,310 participants of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, a prospective study of black and white US adults ≥45 years of age. (nih.gov)
The ageing of the population is a global challenge: current data suggests that by the year 2020 about one fifth of the population of Europe will be aged 65+ years and there will be a tripling of the number of individuals aged 85+ years by 2050. (europa.eu)
It is shown that three hypothetical successful aging strategies, considered equally successful according to the traditional measures restricted to survivors, are associated with vastly different changes in the years lived with and without disability. (bmj.com)
A total of 3000 older people aged ≥60 years participated in the first stage from which 2772 were eligible to participate in the second stage, which started after 2.5 years. (bmj.com)
The findings were that modifiable healthy behaviours during early elderly years, including smoking abstinence, weight management, blood pressure control, and regular exercise, are associated not only with enhanced life span in men but also with good health and function during older age. (nutritionvista.com)
The adults were an average of 60 years of age, the majority were white and 40% were female. (heart.org)
median age was 51 (Q1, Q3: 46, 55) years. (natap.org)
Older age, Black race, 10 years on ART, history of thymidine analog (TA), greater BMI, high waist circumference, hypertension and physical inactivity were associated with physical function impairment in univariate analyses (figure). (natap.org)
The aim of this study was to evaluate the effect of fractures on survival in MM using data from MM patients diagnosed in Sweden in the years 1990-2013, identified from the Swedish Cancer Registry. (haematologica.org)
all patients had Durie-Salmon stage III, bone lesions, and a median age of 62 years. (haematologica.org)
However survival can range from a few months to a number of years. (iospress.com)
Of 838 women included, half were diagnosed between the ages 40 and 59 years. (who.int)
IPF carries a poor prognosis, with a 5-year survival of nearly 50% and mean survival time estimated at 3.2 to 5 years after diagnosis 5 . (jrheum.org)
It means that the average age of mothers when they give birth to an eve lamb is 5.1 years. (nfshost.com)
If survival and reproduction are continuous processes without any cyclic change, then any time units may be suitable: days, weeks, months, years. (nfshost.com)
Patients are primarily older than age 60 years. (medscape.com)
The prognosis is poor and no cure has been found, with a reported median survival of 3-5 years from diagnosis . (medscape.com)
their average age was 49.6±16.5 years. (bvsalud.org)
RESULTS: Of 1,159 participants studied, 949 had type 1 diabetes (mean age 17.1 4.7 years, 60.3% non-Hispanic White, 55% female) and 210 had type 2 diabetes (mean age 22.1 3.5 years, 23.8% non-Hispanic White, 71% female) at initial assessment when diabetes duration was 7.9 years (both groups). (cdc.gov)
Sleep Problems in Children Most children sleep for a stretch of at least 5 hours by age 3 months but then have periods of night waking later in the first years of life, often when they have an illness. (msdmanuals.com)

The United States is in the midst of an age shift in its working population unparalleled since the end of the World War II. (cdc.gov)
It is recommended that research on successful aging should be based on summary measures of population health that reflect both survival and functioning throughout life. (bmj.com)
With an [aging] population which is looking to live healthier for longer, these studies are critical to people enjoying a productive and satisfying quality of life," Wheeler added. (naturalnews.com)
We considered the population of the two-age classes by the beginning of the next season: the younger, one including not reproductive individuals, and the senior class, consisting of the individuals participating in reproduction. (sgu.ru)
According to this supposition the density-dependent factors restrict the development of population. (sgu.ru)
In nature, mortality and reproduction rate may depend on numerous factors: temperature, population density, etc. (nfshost.com)
Age-dependent life-tables can be built for the entire population only if the breeding period is short and therefore organisms' development is synchronized. (nfshost.com)
Annual incidence rates were age or age/sex adjusted to the 2000 US population. (cdc.gov)
RESULTS: Of 139 incident cases there were 126 cases by the EULAR/ACR criteria, corresponding to an age/sex-adjusted incidence of 4.5 per 100000 population (95% CI: 3.7, 5.2). (cdc.gov)
Access to rehabilitation and assistive products is vital for achieving Universal Health Coverage (UHC), especially considering the growing need for rehabilitation in the Africa Region due to factors such as the increasing incidence of injuries, stroke, the survival of people living with the consequences of injuries, and the aging population. (who.int)

This study demonstrates that pleural effusions rich in a range of soluble factors are associated with poor prognosis. (iospress.com)
These patients have a poor prognosis, with unselected large series revealing median survivals between 7 and 11 months [ 3 , 4 ]. (iospress.com)
However, other studies showed that CTD-ILD was associated with a worse prognosis than IPF when adjusted for age 9 , 10 . (jrheum.org)
The age at which the condition begins and the prognosis are affected by the specific genetic factors involved in the condition. (medlineplus.gov)

Brain-derived neurotrophic factor (BDNF) promotes the survival of neurons by regulating nerve function, promoting nerve growth, increasing synaptic plasticity, and delivering efficiency ( 18 ). (frontiersin.org)
It could prevent the pathological changes of stroke, inhibit the apoptosis of neurons and effectively improve the neural function of stroke patients ( 6 ). (frontiersin.org)
Vitamin D deficiency causes neuronal apoptosis and hinders the growth and survival of neurons, leading to the impairment of neurological function. (yahoo.com)
BDNF is a protein involved in many important processes in the brain , such as the growth and survival of information-transmitting neurons. (naturalnews.com)

Both age and type of work are important predictors of musculoskeletal disorders. (cdc.gov)
PANINI researchers have studied in detail the predictors of different measures of health and wellbeing among middle-aged and older people including hormones, muscle strength and function, genetics, and stress. (europa.eu)
Older age, lower preoperative eGFR, smaller tumor size, tumor located in renal pelvis, and absence of hydronephrosis or multifocality were predictors of postoperative renal insufficiency. (hindawi.com)

By 2020, 41% of all men and 32% of all women between the ages of 65-69 will be working, a 22% proportional increase in men and 35% proportional increase in women compared with average participation rates from the last decade. (cdc.gov)

Black race, greater BMI and physical inactivity remained associated with physical function impairment in the multivariate model. (natap.org)

Survival at last followup from time of ILD diagnosis was calculated using the Kaplan-Meier estimator. (jrheum.org)

Juvenile Plasma Factors Improve Organ Function and Survival following Injury by Promoting Antioxidant Response. (augusta.edu)

IPF is the most common interstitial lung disease among middle-aged and older adults . (medscape.com)

We previously showed that the toxicity is both linked to a loss and a gain of function of the mutant protein but the neuronal role of the TG6 is still not known. (ataxia.org)
2-4 Proinflammatory cytokines such as interferon-γ and tumor necrosis factor-α might affect development of depressive disorder by regulating neuronal excitability, synaptic transmission, synaptic plasticity, and neuronal survival. (psychiatrist.com)

In a longitudinal study of 572 adults with type 2 diabetes , after adjustment for potential confounders metformin use was significantly associated with improved myocardial perfusion reserve (MPR), a measure of coronary microvascular function, and longer survival. (medscape.com)
One Dutch longitudinal study found better survival in long-lived siblings compared to sporadic long-livers [ 10 ]. (aging-us.com)

Although radical nephroureterectomy (RNU) with excision of the bladder cuff is the gold-standard treatment for upper tract urothelial carcinomas (UTUC) [ 1 ], the oncologic outcomes for patients with high-grade or non-organ-confined disease remain poor, with 5-year cancer-specific survival rates less than 60% [ 2 - 4 ]. (hindawi.com)
Additionally, nNIF still improved stroke outcomes when administered after stroke onset and blocked NET formation after stroke without affecting other critical neutrophil functions. (heart.org)
Several studies comparing IPF with CTD-ILD indicate that patients with IPF experience poorer outcomes and survival 6 , 7 , 8 . (jrheum.org)

Whyte and Mulsant ( 7 ) put forward that PSD is under the bio-psycho-social medical model, and both biological factors and psychological factors could cause the onset of PSD. (frontiersin.org)
As sarcopenia is a complex condition brought on with the onset of multiple factors, it is often undiagnosed and undertreated in day-to-day clinical practice. (medscape.com)
Factors that contribute to onset and progression of heart failure in Fontan patients remain incompletely understood. (stanford.edu)

Age-related changes in musculoskeletal function do not necessarily translate into disability. (cdc.gov)
Furthermore, the intervention considered most successful when considering multiple successful aging measures, was associated with the largest increase in the time lived with disability. (bmj.com)
The model of disability that continues to be systematically developed by The World Health Organization (WHO) considers the ongoing interaction between one's health and contextual factors. (physio-pedia.com)
[1] This page introduces the International Classification of Functioning, Disability, and Health (ICF) and reviews the changes and progress made in conceptualising and measuring disability. (physio-pedia.com)
The biggest changes in ICIDH-2 compared to the original ICIDH included the addition of two new dimensions: participation in social activities and listing environmental factors, which is important for understanding the complexity of disability. (physio-pedia.com)
Rehabilitation plays a crucial role in enhancing everyday functioning and reducing disability by providing rehabilitation services and assistive products that improve independence and well-being. (who.int)

If you have stage III multiple myeloma and you're unsure about what staging means or what your survival rate looks like, ask your doctor to explain it to you. (webmd.com)
The effects of multiple myeloma on your bone health, kidney function, and blood count can take a toll on your overall quality of life. (webmd.com)
The impact of fractures on multiple myeloma (MM) survival is unclear. (haematologica.org)

There were conflicting results on the comparison of brain-derived neurotrophic factor (BDNF) levels between poststroke depression (PSD) patients and stroke patients without PSD among previous studies. (frontiersin.org)
BDNF is a secretory growth factor that mainly contributes to the regeneration of nerve and the development and plasticity of the nervous system via tyrosine kinase receptor B (TrkB) ( 19 ). (frontiersin.org)
The researchers also measured serum levels of brain-derived neurotrophic factor (BDNF). (naturalnews.com)

To report the decline of renal function after radical nephroureterectomy (RNU) in upper tract urothelial carcinoma (UTUC) patients and to develop a nomogram to predict ineligibility for cisplatin-based adjuvant chemotherapy (AC). (hindawi.com)
Several reports have evaluated changes in renal function following RNU and demonstrated that the decline in renal function may render a substantial number of patients ineligible to receive adjuvant chemotherapy (AC) [ 10 - 15 ]. (hindawi.com)
Metformin associates with improved myocardial perfusion reserve and survival in patients with Type 2 Diabetes Mellitus," by researchers primarily affiliated with the University of Leeds, Leeds, UK, on medRxiv and provided to you by Medscape. (medscape.com)
The separation of UBX1325-treated patients from sham-treated patients at 18 weeks in measures of both visual function and retinal structure following a single UBX1325 injection suggests that one dose could have a durable therapeutic effect. (marketscreener.com)
No significant difference in survival was observed between MM patients who developed a fracture during follow up as compared to patients that did not develop a fracture. (haematologica.org)
Accurate prediction of survival is important for patients to plan for their remaining life, and for clinicians to determine appropriate therapy. (iospress.com)
We profiled the cellular constituents and concentrations of 40 cytokines, chemokines and cellular factors (collectively "soluble factors") involved in inflammatory and immune signalling pathways in pleural effusion samples from 50 mesothelioma patients. (iospress.com)
An accurate prediction of survival is needed to enable patients and clinicians to decide on treatment, and to plan and prioritise in the setting of an incurable cancer. (iospress.com)
To compare survival of patients with connective tissue disease-associated interstitial lung disease (CTD-ILD) versus idiopathic pulmonary fibrosis (IPF) and patients with systemic sclerosis-associated ILD (SSc-ILD) versus other CTD-ILD followed at our center. (jrheum.org)
Patients with SSc-ILD (n = 24) experienced better survival than those with other CTD-ILD (n = 38), with 1-year, 3-year, and 5-year survival rates of 100%, 90%, and 77%, respectively, versus 78%, 42%, and 38% (p = 0.01). (jrheum.org)
Survival in patients with SSc-ILD was better than in patients with other CTD-ILD, potentially related to routine screening for and early detection of ILD in patients with SSc at our center. (jrheum.org)
Therefore, guidelines have been published recommending that all patients with SSc undergo baseline and annual screening for ILD with pulmonary function testing and chest imaging 13 , 14 . (jrheum.org)
A recent double-blind placebo-controlled study showed that patients with SSc-ILD treated with 1 year of oral cyclophosphamide experienced a statistically significant improvement in lung function, dyspnea, and health-related quality of life compared with those treated with placebo 15 , 16 . (jrheum.org)
The effect of cyclophosphamide therapy on longterm survival in patients with SSc-ILD is still unclear. (jrheum.org)
We compared the clinical features and survival of patients with SSc-ILD to those with ILD associated with other CTD (non-SSc CTD-ILD), including RA, SLE, PM/DM, Sjögren's syndrome, and MCTD. (jrheum.org)
We also identified factors predictive of mortality in patients with CTD-ILD. (jrheum.org)
By the age of 40, 50% of Fontan patients will have died or undergone heart transplantation. (stanford.edu)
Patients with confirmed COVID-19 admitted to intensive care units have a high mortality rate, which appears to be associated with increasing age, male sex, smoking history, hypertension and diabetes mellitus. (bvsalud.org)

ABSTRACT The 5-year survival rate of female breast cancer cases in Jordan and some of the factors that affected survival were measured. (who.int)

Dairy cows are often culled at quite young ages due to an inability to cope adequately with metabolic and infectious diseases, resulting in reduced milk production and infertility. (biomedcentral.com)
The supplement uses ingredients such as green tea extract to improve thermogenesis and boost metabolic function. (mi-reporter.com)
Most human age-related metabolic diseases and disorders are due to oxidative damage, which plays a fundamental role in age-related metabolic changes such as cataract. (molvis.org)

Higher ACR values were associated with lower stroke-free survival in both black and white participants. (nih.gov)
Studies reported that educational level ( 10 ), age ( 11 ), gender ( 12 ), preexisting personality characteristics of the patient ( 13 ), the marital status of the patient, the severity of stroke ( 14 ), chronic diseases ( 15 ), and social support ( 16 ) are correlated with the occurrence of PSD. (frontiersin.org)
A naturally occurring protein that blocks this inflammatory immune response, known as neonatal NET-inhibitory factor, or nNIF, was associated with better stroke recovery in a study conducted in mice. (heart.org)
The mice that were pretreated with nNIF had reduced brain injury, improved neurological and motor function and enhanced survival after stroke. (heart.org)

The generation of an in vivo model of SCA35 can be of use to better understand the molecular mechanisms induced by TG6 loss of function and find new therapeutic avenues for this disease. (ataxia.org)
In many forms of human retinal disease, including age-related macular degeneration (AMD), the underlying pathogenesis resides within the support cells of the retina, the retinal pigment epithelium (RPE). (ca.gov)
Long-term visual function is maintained in this model of retinal disease even though the xenografted cells are eventually lost, suggesting a secondary protective host cellular response. (ca.gov)
It can occur as a consequence of disease (cancers, chronic disorders), malnutrition, inactivity, or a combination of these factors. (medscape.com)
7 6 In MM bone disease, the interaction between malignant plasma cells and the bone microenvironment leads to osteoclastic bone destruction, reduced osteoblast function, and blocking of bone repair. (haematologica.org)
Regulation of NAD(+) metabolism in aging and disease. (augusta.edu)
Aging and Disease , 13 (2), 568-582. (elsevierpure.com)
Survival was decreased with the presence of hypertension, diabetes mellitus, low blood oxygen saturation (BOS), severe or critical stage disease. (bvsalud.org)

Sarcopenia has been widely studied in individuals with cancer and is considered an independent predictor of poor physical function, lower quality of life, surgical complications, cancer progression, and reduced survival. (medscape.com)

These cells might be a potential source for therapies to treat age-related macular degeneration. (ca.gov)
Warburg Effect as a Novel Mechanism for Homocysteine-Induced Features of Age-Related Macular Degeneration. (augusta.edu)

The number or proportion of organisms surviving to any age is plotted on the y-axis (generally with a logarithmic scale starting with 1000 individuals), while their age (often as a proportion of maximum life span) is plotted on the x-axis. (wikipedia.org)
Finally, if an outside element only reduces the survival of organisms later in life, this is likely to yield a Type I curve. (wikipedia.org)
Studies have shown that factors in the blood of young organisms can rejuvenate the old ones. (elsevierpure.com)
Age-dependent life table shows organisms' mortality (or survival) and reproduction rate (maternal frequency) as a function of age. (nfshost.com)
If organisms breed continuously, then generation time will be overestimated using this equation because all births are summed over the period between census dates which is equal to one age step. (nfshost.com)
However, it may be not very dangerous if reproduction is limited to a short period within the year because there will be little age difference between organisms born in the same year. (nfshost.com)
Bioconcentration Factor (BCF)--The quotient of the concentration of a chemical in aquatic organisms at a specific time or during a discrete time period of exposure divided by the concentration in the surrounding water at the same time or during the same period. (cdc.gov)

This paper investigates the roles psychological biases play in deviations between subjective survival beliefs (SSBs) and objective survival probabilities (OSPs). (netspar.nl)
Survival probabilities l x are often plotted against age x. (nfshost.com)

Postoperative renal function was not associated with worse survival. (hindawi.com)
If you have other chronic conditions like diabetes or high blood pressure , especially if they're not well-controlled, it may mean a worse survival outlook. (webmd.com)

These studies showed that lifespan is partly heritable, and that the heritability increases with age. (aging-us.com)
Researchers concluded "alkaline water provides higher longevity in terms of 'deceleration aging factor,' as it increases the survival functions. (flowhydration.com)

[1] The contextual factors affecting a person's health include the real-life environment, social interactions, and social participation. (physio-pedia.com)

Netspar, Network for Studies on Pensions, Aging and Retirement, is een denktank en kennisnetwerk. (netspar.nl)
Previous studies have shown that skeletal-related events (radiation to the bone, a pathologic or osteoporotic fracture, hypercalcemia, spinal cord compression, or surgery to the bone) are associated with reduced survival in both breast cancer and prostate cancer. (haematologica.org)
Studies using heterochronic parabiosis models further reinforced the hypothesis that juvenile factors can rejuvenate aged systems. (elsevierpure.com)
A total of 1,156 long-lived female siblings were selected from three nationwide Danish studies and age-matched with sporadic long-lived female controls. (aging-us.com)
As highlighted in several Scandinavian twin studies, longevity clusters in families, which suggests the existence of genetic variants for survival [ 5 - 7 ]. (aging-us.com)
Further studies are needed to confirm the results and to ensure the inclusion of other factors. (who.int)
Inoculation with a low dose of increased considerably with age: af- studies provide important mechanis- EBV resulted in apparently asymp- ter 18 months, 42% of the transgen- tic evidence. (who.int)

Information about longer survival, better quality of life, and fewer fluid limits and access complications were all significantly linked with choosing longer and/or more frequent treatments. (homedialysis.org)
Infections, complications, and technique survival were similar as well. (homedialysis.org)

Results for the two soluble factors most significantly and independently associated with survival were validated in an independent set of samples ( n = 51) using a separate assay system. (iospress.com)

Across PANINI it was possible to combine and share datasets and test key markers of ageing, and model the contribution of factors such as genetics and muscle metabolomics to muscle function, frailty and survival. (europa.eu)
Age was not related to MoCA score (=-0.1, p=0.19), but was associated with frailty status by Jonckheere-Terpstra (JT) test (p=0.008). (natap.org)

There are three generalized types of survivorship curves: Type I or convex curves are characterized by high age-specific survival probability in early and middle life, followed by a rapid decline in survival in later life. (wikipedia.org)
Type II or diagonal curves are an intermediate between Types I and III, where roughly constant mortality rate/survival probability is experienced regardless of age. (wikipedia.org)
Type III or concave curves have the greatest mortality (lowest age-specific survival) early in life, with relatively low rates of death (high probability of survival) for those surviving this bottleneck. (wikipedia.org)
We model deviations between SSBs and OSPs through age-dependent inverse S-shaped probability weighting functions. (netspar.nl)

greater BMI and physical inactivity are important modifiable factors that may prevent further decline in physical function with aging. (natap.org)

Age and Health-Chronic diseases affecting the cardiovascular and musculoskeletal systems inevitably rise as the workforce ages. (cdc.gov)
Here we examined whether long-lived female siblings have a better ability to avoid diseases at ages 65+ (proxy for "robustness") and/or survive to extreme ages (proxy for "resilience") compared to sporadic long-livers. (aging-us.com)

median age 51. (natap.org)

There are various reasons that a species exhibits their particular survivorship curve, but one contributor can be environmental factors that decrease survival. (wikipedia.org)
The results reveal that the loss of BFCNs in pre-symptomatic pR5 tau transgenic mice results in a decrease in hippocampal brain-derived neurotrophic factor levels and reduced TrkB receptor activation. (atsbio.com)

Older age (OR = 1.007), preoperative eGFR (OR = 0.993), absence of hydronephrosis (OR = 0.801), smaller tumor size (OR = 0.962), and tumor without multifocality (OR = 0.876) were predictive for ineligibility for full-dose AC. (hindawi.com)

EFFECTS OF HIV, AGE, AND SEX ON SKELETAL MUSCLE MASS AND DENSITY (04/01/20) "Older age and being a woman was associated with smaller and fattier muscle, while obesity was associated with larger and fattier muscle. (natap.org)

One study indicated a genetic influence on human longevity, underscoring minimal genetic effects on lifespan for people under age 60 and then moderate genetic effects for people aged 60 and over [ 6 ]. (aging-us.com)

Age-related decreases in physical capacity, particularly in peak performance, vary greatly. (cdc.gov)
The production of vitamin D from the skin decreases with age. (yahoo.com)

80% even after correcting for age at ILD diagnosis, sex, and ethnicity (HR = 0.17, 95% CI 0.04-0.83). (jrheum.org)

This is because Drosophila genes controlling fundamental cellular functions, such as cell growth and death, are quite identical to those found in human cells. (ataxia.org)
As a monolayer of cells critical to photoreceptor function and survival, the RPE is an ideally accessible target for cellular therapy. (ca.gov)
Research interests include investigating cellular response to injury and influence of aging using experimental models of trauma and sepsis. (augusta.edu)
BACH1-Hemoxygenase-1 axis regulates cellular energetics and survival following sepsis. (augusta.edu)

At this point the primary objective of randomisation‐exclusion of confounding factors‐has failed. (bmj.com)

Technique and patient survival were comparable, though hospitalizations and temporary in-center HD were common. (homedialysis.org)

The participants were males and females aged 55 to 80 who were either overweight or obese at the time of the study and had sedentary lifestyles. (naturalnews.com)
Then, survival rates should be specified separately for males and females, and the sex ratio of offspring should be taken into account. (nfshost.com)

The genetic alteration causative of SCAN-1 is a mutation altering the function of a gene called tdp1 (tyrosyl- DNA phosphodiesterase 1). (ataxia.org)
Is sarcopenia largely driven by nutrition, lifestyle, or genetic factors? (medscape.com)
Both genetic and environmental factors contribute to longevity, and research is increasingly more focused on the genetic part [ 1 - 4 ]. (aging-us.com)
However, few genetic or other pro-longevity factors have been identified, possibly due to "phenocopies" - those individuals that live long by chance. (aging-us.com)
CN-AML is a complex condition influenced by several genetic and environmental factors. (medlineplus.gov)

We hypothesized that changes in physiologic and radiographic parameters would predict survival. (nih.gov)

Results indicated that a combination of the five protective health factors (Body Mass Index, smoking status, alcohol intake, physical activity and cardio respiratory fitness). (nutritionvista.com)
However, the factors that initiate the toxic cascade that results in tau hyperphosphorylation in AD are unknown. (atsbio.com)
Chronic hyperglycemia results in increased oxidative stress and increased generation of advanced glycation end-products, two factors that appear to contribute to generalized atrophy and microvascular changes in the brain [3]. (alzrisk.org)
Progressive deterioration in lung function results in increasing dyspnea, chronic cough, and frequent hospitalizations. (medscape.com)

Anatomy8

Organisms8

Diseases53

Chemicals and Drugs59

Analytical, Diagnostic and Therapeutic Techniques and Equipment84

Phenomena and Processes37

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena2

Humanities1

Information Science8

Named Groups3

Health Care38

Geographicals1

Prognostic5

Hazard ratio1

Cohort6

Regression6

Humans1

Risk43

Prevalence3

Cognitive6

Outcome11

Adequate3

20231

Overall survival3

Graft function1

Years22

Population10

Prognosis4

Neurons4

Predictors3

20201

Multivariate1

Kaplan-Meier1

Organ Function1

Middle-aged and older1

Neuronal2

Longitudinal2

Outcomes3

Onset3

Disability6

Multiple myeloma3

BDNF3

Patients18

Abstract1

Metabolic3

Stroke4

Disease8

Progression1

Macular degeneration2

Organisms7

Probabilities2

Worse2

Increases2

Person's1

Studies7

Complications2

Significantly1

Frailty2

Probability4

Decline1

Diseases2

Median age1

Decrease2

EGFR1

Older1

People aged1

Decreases2

Diagnosis1

Cellular4

Objective1

Patient survival1

Males and females2

Genetic5

Predict1

Results4