Cell DeathCell SurvivalSurvival RateApoptosisCause of DeathDisease-Free SurvivalCaspasesSurvivalSurvival AnalysisDeathGraft SurvivalTime FactorsCaspase 3Signal TransductionNecrosisCell Line, TumorTreatment OutcomeCells, CulturedDNA FragmentationAutophagyMitochondriaProto-Oncogene Proteins c-bcl-2In Situ Nick-End LabelingRetrospective StudiesKaplan-Meier Estimatebcl-2-Associated X ProteinCaspase InhibitorsDeath, Sudden, CardiacReactive Oxygen SpeciesAntineoplastic AgentsCell LineFollow-Up StudiesAntigens, CD95NeuronsEnzyme ActivationMice, Inbred C57BLBrain DeathApoptosis Regulatory ProteinsCell ProliferationBlotting, WesternImmunohistochemistryMutationbcl-X ProteinFetal DeathNeoplasm StagingAmino Acid Chloromethyl KetonesProto-Oncogene ProteinsPrognosisTumor Cells, CulturedTumor Suppressor Protein p53Mice, KnockoutCytochromes cCaspase 8Poly(ADP-ribose) PolymerasesDose-Response Relationship, DrugFas Ligand ProteinCaspase 9Risk FactorsNeoplasmsAntineoplastic Combined Chemotherapy ProtocolsCysteine Proteinase InhibitorsProportional Hazards ModelsRNA, Small InterferingEnzyme InhibitorsModels, BiologicalBreast NeoplasmsTransfectionCombined Modality TherapyLung NeoplasmsDisease Models, AnimalOxidative StressHydrogen PeroxideMembrane Potential, MitochondrialPhosphorylationRNA, MessengerCell DivisionAttitude to DeathDNA DamageCell CycleProspective StudiesMultivariate AnalysisMice, TransgenicReverse Transcriptase Polymerase Chain ReactionMolecular Sequence DataCytoprotectionCohort StudiesReceptors, Death DomainApoptosis Inducing FactorUp-RegulationGene Expression Regulation, NeoplasticMembrane ProteinsInhibitor of Apoptosis ProteinsCisplatinTumor Necrosis Factor-alphaProtein-Serine-Threonine KinasesAge FactorsDown-RegulationRNA InterferenceGene Expression RegulationNeoplasm Recurrence, Local