Survival patient selection. Medical search. Frequent questions

Significant parameters used in the determination of the prognosis and survival of esophageal cancer include tumor stage, surgical margin, and metastatic lymph node status. (researchsquare.com)
Accumulating evidence shows that in addition to the characteristics of the tumor, the immune response of the patient is also highly important for determining the prognosis. (researchsquare.com)
The standard of care for patients with newly diagnosed GBM comprises maximum safe resection of the tumor followed by radiotherapy (RT) with concomitant and adjuvant temozolomide (TMZ) chemotherapy [ 3 , 4 ]. (springer.com)
Studies addressing the effect of timing of RT on survival suffer from considerable bias, such as inhomogeneous patient populations, inhomogenous treatment protocols or disregard for tumor location, EOR, and RTV. (springer.com)
The purpose of this study was to evaluate the timing of RT as a prognostic factor on a homogeneous patient population with only newly diagnosed primary GBM treated with the same treatment scheme, also taking important prognostic factors such as tumor location, MGMT methylation status, EOR and RTV into account. (springer.com)
We retrospectively analyzed all adult patients with a newly diagnosed primary GBM treated according to the EORTC 22981/26981 protocol [ 3 ] at the Brain Tumor Center of the University Hospital of Cologne, Germany between 2010 and 2015. (springer.com)
Even though developed for AML patients, our pan-cancer analyses demonstrate a wider application of the IPRP signature for prognostic prediction and analysis of tumor-immune interplay also in multiple solid tumors. (nature.com)
Compared with solid tumor sampling, the bone marrow or peripheral blood of leukemia patients is easier to access, and therefore an accurate and practical prognostic signature for leukemia patients has potential for more direct clinical application. (nature.com)
Furthermore, compared to the tumor, lymph node, metastasis (TNM) staging system, histone modifications can discriminate the survival difference more accurately, especially for patients with stage I or stage II tumors. (oncotarget.com)
This comparison study shows upfront thermal ablation results in better progression-free-survival compared to delayed ablation, for patients with low tumor burden. (arrs.org)
Particularly, these patients should have a single tumor of 5 cm or smaller in diameter. (medscape.com)
It's an investigator-led study, and it has multiple parallel, placebo-controlled, phase two studies that run in the maintenance setting after first-line chemotherapy for advanced urothelial carcinoma, and the selection for which of these studies you go into is determined by biomarker analyses that are done during the course of the chemotherapy on archival tumor samples. (urotoday.com)
Antiangiogenic therapy has shown clear activity and improved survival benefit for certain tumor types. (mit.edu)
In conclusion, tumor perfusion changes after antiangiogenic therapy may distinguish responders vs. nonresponders early in the course of this expensive and potentially toxic form of therapy, and these results may provide new insight into the selection of glioblastoma patients most likely to benefit from anti-VEGF treatments. (mit.edu)
In the clonal extinction patients, NAC eliminated the tumor cells, leaving only normal cell types post-treatment. (medindia.net)
Clonal persistent patients harbored a larger number of residual tumor cells with genotypes and phenotypes that were altered in response to NAC. (medindia.net)
This study examines the influence of the heterogeneity of tumor proliferation on disease-free survival of patients with a breast carcinoma. (biomedcentral.com)
MAIN OUTCOME MEASURES: Proportional hazards models incorporating geographical region, age, race, pathological stage, lymph node involvement, and tumor grade to identify independent correlates of disease-specific and overall survival and life table analyses to estimate 10-year survival distributions. (laprp.com)
In this context, there is a need for new predictive markers, beyond the tumor stage, to select what patients will benefit from an adjuvant treatment and to better tailor treatment schemes and schedules. (frontiersin.org)
The patient demographics, tumor characteristics, context of STZ chemotherapy, and patient outcome were collected and assessed. (cancerindex.org)
Prevalence of ARID1A Mutations in Cell-Free Circulating Tumor DNA in a Cohort of 71,301 Patients and Association with Driver Co-Alterations. (cdc.gov)
The main focus has been on tumor cell PD-L1 expression, but its assessment alone is insufficient for patient selection in most malignancies. (lu.se)
We mapped the presence of macrophages (CD68 and CD163) and lymphocytes (CD3) located within the tumor epithelium, the cell type-specific expression of PD-L1 and PD-1, and their impact on 5-year overall survival (OS) in a consecutive cohort of 130 women diagnosed with advanced HGSC between 2011 and 2015. (lu.se)
Thus, women with greater lymphocyte tumor infiltration had better outcome and PD-L1/PD-1 expression, regardless of PD-1/PD-L1 being markers for immune suppressive pathways, conferred a survival benefit in our cohort. (lu.se)

In patients with breast cancer receiving adjuvant 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel (FEC-D), we evaluated the impact of chemotherapy total cumulative dose (TCD), and early (FEC) versus late (D only) dose reductions, on survival outcomes. (jnccn.org)
Survival outcomes (disease-free survival [DFS] and overall survival [OS]) were estimated using Kaplan-Meier and multivariate analysis. (jnccn.org)
Conversely, early reductions (FEC±D) negatively affected patient outcomes. (jnccn.org)
We will put this into historical perspective, comparing outcomes across time to help understand the impact of advances in evidence-based treatment on average survival. (biomedcentral.com)
Although radical nephroureterectomy (RNU) with excision of the bladder cuff is the gold-standard treatment for upper tract urothelial carcinomas (UTUC) [ 1 ], the oncologic outcomes for patients with high-grade or non-organ-confined disease remain poor, with 5-year cancer-specific survival rates less than 60% [ 2 - 4 ]. (hindawi.com)
Eymen Ucisik, MD discusses a recently published AJR article aiming to explore the potential of the insular ribbon involvement on the initial MRI as a marker of tissue fate by analyzing serial follow up MRI findings and the affected patients' clinical outcomes. (arrs.org)
However, in patients with severe hemorrhagic shock at risk for cardiovascular collapse, emergency thoracotomy with aortic cross clamping may be performed though outcomes are typically poor. (wikipedia.org)
However, design improvements of the REBOA device and continuously evolving patient selection criteria have subsequently improved REBOA outcomes. (wikipedia.org)
The technical success and midterm outcomes are very satisfactory but require patient selection particularly regarding hemodynamic stability. (lu.se)
We conduct research to improve transplant outcomes provide support and resources for patients, and partner with a global network. (bethematch.org)
Their findings that TNBC patients fall into clonal extinction or clonal persistent groups may be applicable to patient outcomes or survival. (medindia.net)
Comparing Survival Outcomes for Advanced Cancer Patients Who Received Complex Genomic Profiling Using a Synthetic Control Arm. (cdc.gov)

Data sets profiled in various patient cohorts may also have been processed with different data processing methods, making the signatures extracted in one study suboptimal in the other cohorts. (nature.com)
In case of end-stage liver disease that is refractory to all methods of medical treatment, transferring the patient to a facility experienced in liver transplantation is preferable. (medscape.com)
MATERIAL AND METHODS: This is a multicenter retrospective review of all consecutive patients undergoing acute endovascular repair of ruptured aortoiliac aneurysm with an IBD at 8 aortic centers between December 2012 and June 2020. (lu.se)
The median overall survival (OS) and progression-free survival (PFS) were calculated using Kaplan-Meier and Cox regression methods, respectively. (cancerindex.org)
Methods Population-based age-standardised relative survival at 1 year is estimated for 1.4 million patients diagnosed with cancer of the oesophagus, stomach, colon, lung, breast (women) or cervix in England during 1991-2006 and followed up to 2007. (bmj.com)

Treatment patterns including receipt of surgery, radiation, chemotherapy, aromatase inhibitors (AI), and non-AI hormonal therapy were evaluated for study cohort patients with at least 2 months of follow-up. (biomedcentral.com)
In this retrospective multi-cohort study, we investigated whether combining pyroptosis- and immune-related genes improves prognostic classification of AML patients. (nature.com)
We selected all HIV patients included in the COMESEM cohort with TB diagnosis after 1996. (lww.com)
Among the 6934 HIV patients included in the cohort, 1217 patients had TB, 322 of them (26.5%) after 1996. (lww.com)
We have revised the effects on survival of simultaneous versus delayed HAART initiation in TB- and HIV-coinfected patients in a large cohort of HIV-coinfected patients in Spain. (lww.com)
Patients were randomly divided into a training ( n = 134) and validation cohort ( n = 94). (biomedcentral.com)
Therefore, in this large single-center cohort of patients, we sought to reveal the prevalence of CKD before and after RNU and to develop a nomogram to predict ineligibility for AC, which would help to accurately predict postoperative renal function and thus provide more optimal and personalized risk-based therapy options. (hindawi.com)
In a cohort study reported in JAMA Network Open , Wang et al found that overall survival in patients with non-small cell lung cancer (NSCLC) who stopped smoking prior to their cancer diagnosis was better than overall survival among those who were current smokers at the time of their diagnosis. (ascopost.com)
The study involved patients with NSCLC who were recruited to the Boston Lung Cancer Survival Cohort at Massachusetts General Hospital between 1992 and 2022. (ascopost.com)
The investigators concluded, "In this cohort study of patients with NSCLC, quitting smoking early was associated with lower mortality following a lung cancer diagnosis, and the association of smoking history with overall survival may have varied depending on clinical stage at diagnosis, potentially owing to the differing treatment regimens and efficacy associated with smoking exposure following diagnosis. (ascopost.com)
The final study cohort consisted of 16,852 patients, 51% of whom were managed by AS, 36% with initial treatment, and 13% with watchful waiting. (medpagetoday.com)

Approximately 57% of study patients with 2+ months of follow-up received chemotherapy and over 62% received an AI during follow-up. (biomedcentral.com)
Endocrine therapy is the preferred treatment for patients with stage III or IV hormone-receptor-positive (HR +, which includes ER and/or PR positive) breast cancer, but chemotherapy may also be recommended for cases with rapidly progressive disease [ 4 , 5 ]. (biomedcentral.com)
Treatment of early-stage breast cancer with adjuvant chemotherapy has improved survival. (jnccn.org)
The aim of this study was to determine pathologic variables associated with disease-specific survival of node-positive patients with endometrial carcinoma treated with combination of surgery including pelvic and para-aortic lymphadenectomy and adjuvant chemotherapy. (nih.gov)
Survival of 55 node-positive endometrial carcinoma patients prospectively treated with surgery and adjuvant chemotherapy between 1982 and 2002 at Hokkaido University Hospital was compared to various histopathologic variables. (nih.gov)
All patients underwent primary surgical treatment including pelvic and para-aortic lymphadenectomy followed by adjuvant chemotherapy consisting of intravenous cisplatin, doxorubicin, and cyclophosphamide. (nih.gov)
New chemotherapy regimen including taxane needs to be considered as an adjuvant therapy for patients with node-positive endometrial cancer. (nih.gov)
In the ACT IV study, we aimed to assess whether or not the addition of rindopepimut to standard chemotherapy is able to improve survival in patients with EGFRvIII-positive glioblastoma. (nih.gov)
To report the decline of renal function after radical nephroureterectomy (RNU) in upper tract urothelial carcinoma (UTUC) patients and to develop a nomogram to predict ineligibility for cisplatin-based adjuvant chemotherapy (AC). (hindawi.com)
The use of cisplatin-based chemotherapy has gained greater acceptance as evidenced by its use in neoadjuvant and adjuvant therapy, especially in patients with pT3-4 or pTxN+ [ 5 - 8 ]. (hindawi.com)
Several reports have evaluated changes in renal function following RNU and demonstrated that the decline in renal function may render a substantial number of patients ineligible to receive adjuvant chemotherapy (AC) [ 10 - 15 ]. (hindawi.com)
Neoadjuvant chemotherapy followed by interval cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) significantly improves progression-free survival (PFS) and overall survival compared with interval cytoreductive surgery alone in patients with advanced ovarian cancer , new research shows. (medscape.com)
The study, conducted at seven Korean Gynecologic Oncology Group institutions, included 196 patients (mean age, 58 years) with stage III or IV ovarian cancer who had received at least three cycles of neoadjuvant chemotherapy followed by interval cytoreductive surgery with HIPEC (n = 109) or without HIPEC (n = 87). (medscape.com)
This UK-based, investigator-led study focuses on the use of rucaparib in advanced urothelial carcinoma patients who have undergone first-line chemotherapy. (urotoday.com)
So we took patients that had this biomarker, and we randomized them, if they were eligible, to treatment within 10 weeks of completion of chemotherapy, assuming that they did not have progressive disease at the end of the chemotherapy. (urotoday.com)
It is a scary diagnosis, and even though chemotherapy can be effective as standard-of-care, many patients become resistant to treatment. (medindia.net)
Neo-adjuvant chemotherapy (NAC) is the standard of care for many TNBC patients, who lack estrogen and progesterone receptors as well as human epidermal growth factor 2 (HER2) receptor, making them ineligible for hormone or anti-HER2 therapy. (medindia.net)
While NAC is effective in some TNBC patients, approximately half will develop chemotherapy resistance, leading to poor overall survival. (medindia.net)
A major gap in knowledge is whether chemoresistance arises due to the selection and expansion of pre-existing subclones called adaptive resistance or through new mutations resulting from the chemotherapy, a phenomenon known as acquired resistance," said Navin. (medindia.net)
For more than two decades 5-FU-based adjuvant chemotherapy has been the standard of care for patients with stage III and selected stage II CRC. (frontiersin.org)
Streptozocin-Based Chemotherapy in Patients with Advanced Neuroendocrine Neoplasms--Predictive and Prognostic Markers for Treatment Stratification. (cancerindex.org)
Chemotherapy with streptozocin (STZ) in combination with 5-FU or doxorubicin (Dox) represents a standard of care for patients with metastatic pancreatic neuroendocrine neoplasms (pNEN). (cancerindex.org)
STZ-based chemotherapy is an effective and well-tolerated treatment option in patients with well differentiated neuroendocrine neoplasms. (cancerindex.org)
The aim of the present study was to determine the status of STZ usage in Japan and to evaluate the effectiveness and safety of STZ chemotherapy in Japanese NET patients. (cancerindex.org)
The main recipients of STZ chemotherapy were middle-aged patients with pancreatic NET and unresectable liver metastases. (cancerindex.org)

Kaplan-Meier survival analysis was also conducted. (biomedcentral.com)
Survival analyses were performed by the Kaplan-Meier curves and the log-rank test. (nih.gov)
Kaplan-Meier and Cox regression analyses were used to compare progression free survival (PFS) and overall survival (OS) between the groups. (springer.com)
We used publicly available data on 97 patients, and the performance of metastasis prediction was represented by receiver operating char- acteristic (ROC) areas and Kaplan-Meier plots. (lu.se)

From a biological point of view, there are arguments to support an early as well as a late initiation of RT: οn the one hand, an early start of RT could have a negative impact on survival due to reduced radiosensitivity secondary to postoperative hypoxia or due to the "second-impact" effect leading to a further deterioration of the clinical condition of an already compromised patient [ 19 , 20 ]. (springer.com)
Since most hematological malignancies are very heterogeneous diseases, robust patient-specific prognostic signatures are required for clinical applications. (nature.com)
To explore survival-related ATIRE events in lung squamous cell carcinoma (LUSC), ATIRE profile, gene expression data, and corresponding clinical information of LUSC patients were downloaded from the TCGA database. (biomedcentral.com)
Detailed smoking history collection should be incorporated into future epidemiological and clinical studies to improve lung cancer prognosis and treatment selection. (ascopost.com)
Some of the approaches incorporating these targets have already translated to measurable clinical benefit: sipuleucel-T (Provenge) and cabazitaxel (Jevtana) have demonstrated improvements in median survival of 4.1 and 2.4 months, respectively, in different populations of men with castration-resistant disease. (cancernetwork.com)
However, while our knowledge of biology has enabled us to design more specific treatments, patients are still entered in phase III trials based on clinical rather than molecular parameters. (cancernetwork.com)
Clinical trial design, and eventually clinical practice, needs to focus on using biological phenotype rather than symptoms or number of prior chemotherapeutic regimens as the basis for selecting the proper treatment for a patient. (cancernetwork.com)
Appropriate patient selection using clinical and echocardiographic characteristics is of paramount importance for achieving acceptable final results. (intechopen.com)
Here, we shed light on mechanisms of nGBM response to cediranib, a pan-VEGF receptor tyrosine kinase inhibitor, using MRI techniques and blood biomarkers in prospective phase II clinical trials of cediranib with chemoradiation vs. chemoradiation alone in nGBM patients. (mit.edu)
In contrast, patients with self-reactive cells have significant autoimmune features in addition to their clinical and molecular immunodeficient state. (hindawi.com)
BioHope is a leading biomedical company specialized in the development of novel diagnostic tools and advanced therapies for clinical management of organ transplanted patients. (europa.eu)
Thanks to the wide experience in molecular biology and medicine of the company´s team and the extensive research performed by the company in the field of immunology, BioHope has developed and patented a disruptive tool for efficient global clinical management of patients undergoing a kidney transplant. (europa.eu)
However, all these solutions cannot be currently implemented in the clinical routine because of the lack of effective means for monitoring allograft function and rational based approaches towards selection of the optimal immunosuppressive therapy. (europa.eu)
This has driven the search for more patient-centric models for early, accurate selection of lead candidates for further clinical development. (moleculardevices.com)
The challenge - accurate selection of compounds from early screens, for further development and clinical testing. (moleculardevices.com)
This study aimed to describe the clinical, microbiological, molecular epidemiology and treatment of multidrug resistant tuberculosis (MDRTB) cases in the UK and to determine factors associated with survival. (bmj.com)
1, 2 Clinical drug resistance is becoming of increasing importance worldwide and is attributed to factors including patient non-adherence to treatment, inappropriate treatment regimens, drug malabsorption, and a poor health infrastructure needed for the effective delivery of treatment. (bmj.com)
There are clinical challenges related to adjuvant treatment in colorectal cancer (CRC) and novel molecular markers are needed for better risk stratification of patients. (frontiersin.org)
Our aim was to integrate our previously reported clinical-genetic prognostic score with new immunogenetic markers of 5-year disease-free survival (DFS) to evaluate the recurrence risk stratification before fluoropyrimidine (FL)-based adjuvant therapy. (frontiersin.org)
The integration of IFNG -rs1861494 in our previous clinical genetic multiparametric score of DFS improved the patients' risk stratification (Log-rank P = 0.0026 in the pooled population). (frontiersin.org)
Our survey showed the clinical benefit and safety of STZ therapy for Japanese patients with unresectable NET. (cancerindex.org)
We compared the power of gene expression measurements with that of conventional prognostic markers, i.e., clinical, histo- pathological, and cell biological parameters, for predicting distant metastases in breast cancer patients using both established prognostic indices (e.g., the Nottingham Prognostic Index (NPI)) and novel combinations of conventional markers. (lu.se)

Postoperative therapy and follow-up modality need to be individualized according to LVSI and the number of positive PAN for stage IIIc patients. (nih.gov)
Postoperative renal function was not associated with worse survival. (hindawi.com)
Besides, we evaluated the association between postoperative renal function and survival. (hindawi.com)
Patients underwent nephron-sparing surgery instead of RNU, with bilateral synchronous UTUC, and previous histories for UTUC, incomplete data on pre- or postoperative serum creatine (Scr), or no follow-up data were excluded. (hindawi.com)
We observed a significantly superior survival benefit associated with [interval cytoreductive surgery] with HIPEC, without higher rates of postoperative complications," the authors concluded, adding that "the survival benefit remained consistent, irrespective of maintenance therapy. (medscape.com)
The preoperative NLR-PLR score is a useful predictor of postoperative survival in the patients with stage I-II gastric cancer and may help identify high-risk patients for rational therapy and timely follow-up. (biomedcentral.com)
Therefore, a preoperative predictor of postoperative survival in the patients with stage I-II gastric cancer would be useful. (biomedcentral.com)
To test our hypothesis that an integrated indicator may better reflect the balance of host inflammation, we determined the prognostic value of NLR-PLR in predicting postoperative survival of the patients with stage I-II gastric cancer. (biomedcentral.com)

Among 303 consecutive endometrial cancer patients treated during the period of this study, 55 patients (18.2%), including 44 without peritoneal metastasis (FIGO stage IIIc) and 11 with peritoneal metastasis (FIGO stage IV), were found to have retroperitoneal lymph node metastasis. (nih.gov)
Multivariate Cox regression analysis revealed that peritoneal metastasis and lymph-vascular space invasion (LVSI) were independently related to poor survival in node-positive endometrial carcinoma. (nih.gov)
The patients with stage I-II gastric cancer have a relatively good prognosis, but recurrence or metastasis is often difficult to predict in such patients. (biomedcentral.com)
Patients with solitary colorectal metastasis to the liver have up to a 40% 5-year survival, and patients with multiple metastases (up to four lesions) have been reported to have survival rates of 22% if all visible disease can be resected. (bcmj.org)
However, liver metastases are common in NET patients and the outcome of NET liver metastasis is poor. (cancerindex.org)
About 20%-40% of patients have metastasis at the initial laparotomy. (medscape.com)

Prediction of overall survival in patients with Stage I esophageal cancer: A novel web-based calculator. (bvsalud.org)

At the time of TB diagnosis, 45% of them started HAART (ST). There were no differences between groups regarding basal characteristics, except for a lower viral load in ST patients. (lww.com)
The selection and randomisation processes were well outlined and baseline characteristics of the patients were similar in the two treatment groups. (bmj.com)
Across regions, overall survival varied by patient and prostate cancer characteristics while disease-specific survival varied substantially by prostate cancer but not patient characteristics. (laprp.com)
The aim of this study was a retrospective evaluation of the clinicopathological characteristics of pNEN patients receiving STZ-based chemotherapies and to identify predictive and prognostic markers. (cancerindex.org)

https://zhangzhiqiao8.shinyapps.io/Artificial_Intelligence_Survival_Prediction_for_CRC_B1005_1/ , which was valuable for individualized treatment decision before surgery. (biomedcentral.com)
Using 5 AML cohorts ( n = 1327 patients total), we demonstrate that the IPRP score leads to more consistent and accurate survival prediction performance, compared with 10 existing signatures, and that IPRP scoring is widely applicable to various patient cohorts, treatment procedures and transcriptomic technologies. (nature.com)
Compared to current standards for AML patient stratification, such as age or ELN2017 risk classification, we demonstrate an added prognostic value of the IPRP risk score for providing improved prediction of AML patients. (nature.com)
The AITRE-based model might serve as a novel tool for LUSC survival prediction. (biomedcentral.com)
However, there are still a substantial portion of patients who undergo non-response, side effects and adverse reactions after targeted therapy, underscoring the critical need for accurate prediction models for cancer prognosis and new therapeutic targets. (biomedcentral.com)
Here, we aimed to develop a prediction model using ATIRE to predict overall survival (OS) of individuals affected by lung squamous cell carcinoma (LUSC). (biomedcentral.com)
The prediction model we developed showed a good performance in calculating the OS rates in patients with Stage I EC. (bvsalud.org)

Cox proportional hazards regression followed by least absolute shrinkage and selection operator algorithm were performed to identify survival-related ATIRE sites and to generate ATIRE risk score. (biomedcentral.com)

Our research found that a greater extent of resection could significantly increase the OS of patients with low-grade gliomas. (biomedcentral.com)
In a longitudinal study of 572 adults with type 2 diabetes , after adjustment for potential confounders metformin use was significantly associated with improved myocardial perfusion reserve (MPR), a measure of coronary microvascular function, and longer survival. (medscape.com)
The results confirm previous reports that metformin treatment of adults with type 2 diabetes significantly associates with improved overall survival. (medscape.com)
I were identified to generate the risk score, of which high levers were significantly associated with worse OS and progression-free survival in both the training and validation sets. (biomedcentral.com)
Among ever-smokers, doubling the years of smoking cessation was associated with significantly prolonged survival (HR = 0.96, 95% CI = 0.93-0.99, P = .003), whereas doubling of smoking pack-years was associated with nonsignificantly poorer survival (HR = 1.03, 95% CI = 0.98-1.07, P = .21). (ascopost.com)
However, Cox proportional regression showed that tumour stage was the only factor that significantly influenced survival analysis after controlling for other factors. (who.int)

Rindopepimut did not increase survival in patients with newly diagnosed glioblastoma. (nih.gov)
To increase survival among these patients the concept of the chain of survival has emerged. (bmj.com)
Because nearly half of cardiac arrest events are witnessed, efforts to increase survival rates should focus on timely and effective delivery of interventions by bystanders and emergency medical services (EMS) personnel. (cdc.gov)
This could increase survival rates and lead to opportunities to bring back elderly and clinically unfit patients into a selection criteria for intensive therapy. (york.ac.uk)

The trial employs biomarker analyses to determine patient eligibility, specifically looking at DNA repair efficiency. (urotoday.com)
The present analyses provide the most generalizable current estimates of survival after radical prostatectomy. (laprp.com)

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest human malignancies, with a 5-year survival rate of only 5% and a median survival of less than 6 months[ 1 ]. (oncotarget.com)
Median survival in patients treated with three drugs to which the bacterium was susceptible on in vitro testing (n=62) was 2066 days (95% CI 1336 to 2515) or 5.66 years, whereas in those not so treated (n=13) survival was 599 days (95% CI 190 to 969) or 1.64 years. (bmj.com)

Eligible patients had newly diagnosed glioblastoma confirmed to express EGFRvIII by central analysis, and had undergone maximal surgical resection and completion of standard chemoradiation without progression. (nih.gov)
2 In contrast, a delay in the antiretroviral treatment, especially in highly immunosuppressed patients, may be dangerous because of progression of AIDS and development of new opportunistic diseases. (lww.com)
Additionally, some centers have promoted REBOA deployment in patients with hypotension at risk for progression to severe hemorrhagic shock but who do not yet meet criteria for emergency thoracotomy with aortic cross clamping. (wikipedia.org)
The primary endpoint, progression-free survival, showed a significant improvement in patients receiving rucaparib compared to those on placebo, with a hazard ratio of 0.53. (urotoday.com)
The majority of patients transitioning to definitive treatment did so for pathological reasons -- grade progression in 51.5% and volume progression in 8.5% -- while 11.1% went on to definitive treatment without progression. (medpagetoday.com)
While 51.5% of patients underwent treatment following grade progression, the reason for treatment was unknown in nearly 30%, making it difficult to know with certainty the root of these differences," wrote Sessine and Tosoian. (medpagetoday.com)
Patients were followed from the date of their diagnosis until the start of definitive treatment, loss to follow-up, death, metastatic progression, or data lock (Dec. 31, 2017). (medpagetoday.com)
The median progression-free and overall survival periods were 11.8 and 38.7 months, respectively, and sustained stable disease was obtained in some selected patients. (cancerindex.org)

During a median follow-up of 28.2 months, 128 patients (65%) had a recurrence and 30 died (15.3%) - 8.3% in the HIPEC group and 24.1% in the non-HIPEC group. (medscape.com)
As many as 55% of patients with recurrence have metastatic lesions to the liver at the time that their recurrence is discovered. (medscape.com)
High recurrence rates, poor survival, and significant alterations in speech and swallowing function are common experiences for patients with malignancies in these anatomic sites. (medscape.com)

This study demonstrates improved rates of complete pathologic necrosis for patients with HCC who underwent thermal ablation and TARE therapies, when compared to those who received TACE. (arrs.org)
Patients underwent 18 F-FLT PET/CT before treatment (PET1) and after NAT (PET2). (escholarship.org)
PATIENTS: Patients who were diagnosed with prostate cancer between 1983 and 1987 and underwent radical prostatectomy and lymph node dissection. (laprp.com)

This result supported that FLs monotherapy is the preferred treatment for a patient with stage II disease, even if the routine administration of adjuvant therapy is not recommended in these patients. (frontiersin.org)

Historically, patients presenting with colorectal cancer metastases to the liver are deemed suitable for curative resection only 30% of the time. (bcmj.org)
As a result, there has been significant interest and research in the field of minimally invasive treatment for patients with colorectal cancer metastases to the liver. (bcmj.org)
In addition, 25% of patients with colorectal cancer die of hepatic failure secondary to the metastatic disease. (bcmj.org)

18F-FLT PET/CT as a Prognostic Imaging Biomarker of Disease-Specific Survival in Patients with Primary Soft-Tissue Sarcoma. (escholarship.org)
18 F-FLT PET/CT as a Prognostic Imaging Biomarker of Disease-Specific Survival in Patients with Primary Soft-Tissue Sarcoma. (escholarship.org)
The purpose of this study was to evaluate 18 F-FLT PET/CT as an early prognostic imaging biomarker of long-term overall survival and disease-specific survival (DSS) in soft-tissue sarcoma (STS) patients treated with neoadjuvant therapy (NAT) and surgical resection. (escholarship.org)
Older age and black race were independently associated with worse overall but not disease-specific survival. (laprp.com)
Estimates of 10-year disease-specific survival ranged from 75% to 97% for patients with well-differentiated and moderately differentiated cancers and from 60% to 86% for patients with poorly differentiated cancers. (laprp.com)

Adult patients had similar levels of these analytes regardless of outcome. (cdc.gov)
Although this technique has been successfully deployed in adult patients, it has not yet been studied in children. (wikipedia.org)
We have several programs and features unique to our center, including the Adolescent and Young Adult Program (AYA), Transplant Optimization Program (TOP) for our older adult patients, and an outpatient stem cell transplant unit which allows us to offer outpatient transplant to eligible patients. (bethematch.org)
In this paper we present estimates of 1-year age-standardised relative survival among adult patients (aged 15-99 years) diagnosed with a cancer of the oesophagus, stomach, colon, lung, breast (women) or cervix in the 28 cancer networks (as geographically defined in 2009) in England during 1991-2006 and followed up to 31 December 2007. (bmj.com)
In addition to the samples from the 55 pediatric patients, people less than 21 years of age, who had laboratory-confirmed Ebola virus disease, we selected samples from 50 adult patients, more than 21 years of age, who had laboratory-confirmed infection. (cdc.gov)
A total of 45 of the 55 pediatric patients and 49 of the 50 selected adult patients had sufficient serum available for the proposed studies. (cdc.gov)
We found that a higher percentage of pediatric than adult patients exhibited hemorrhage, but overall case-fatality rates remained lower for children than for adults. (cdc.gov)

The primary outcome will be survival time from diagnosis. (biomedcentral.com)
This article describes experiences in the community of Göteborg over 20 years with regard to treatment, outcome, and predictors of outcome among patients hospitalised alive after out of hospital cardiac arrest. (bmj.com)
A successful BMV procedure results in reducing the symptoms and improving the long-term outcome of the patients. (intechopen.com)
For the 50% of patients, whose outcome is chronic rejection, this could be prevented by the early identification of this phenomenon and adjustment (increase/change) of immunosuppressive therapy. (europa.eu)
Risk Stratification for Breast Cancer Patient by Simultaneous Learning of Molecular Subtype and Survival Outcome Using Genetic Algorithm-Based Gene Set Selection. (cdc.gov)
The potential for improved outcome in patients with hepatic metastases from colon cancer: A population-based study. (cancercentrum.se)
A population-based study on the management and outcome in patients with locally recurrent rectal cancer. (cancercentrum.se)
Despite these frustrations, patients are potentially curable and should be offered regimens that carefully consider morbidity and outcome within the context of the patient's overall medical condition. (medscape.com)

To evaluate the effect of timing of radiotherapy (RT) on survival in patients with newly diagnosed primary glioblastoma (GBM) treated with the same therapeutical protocol. (springer.com)

0.001), shorter survival (survival at 36 months 28% vs. 62%) and higher resource utilization across all settings except for oral prescription drugs. (biomedcentral.com)

We used a series of multiplex assays to measure the concentrations of 55 serum analytes in specimens from patients from that outbreak to identify biomarkers specific to pediatric disease. (cdc.gov)
Pediatric patients who survived had higher levels of the chemokine regulated on activation, normal T-cell expressed and secreted marker and lower levels of plasminogen activator inhibitor 1, soluble intracellular adhesion molecule, and soluble vascular cell adhesion molecule than did pediatric patients who died. (cdc.gov)
Pediatric patients have been underrepresented in EVD studies because total numbers of affected children in any given EVD outbreak, whether associated with EBOV, SUDV, or Bundibugyo virus, are usually low because of outbreak dynamics and societal structure. (cdc.gov)
The CFR for pediatric patients in this outbreak was lower than for adults ( 6 ), but the reasons for this increased survival were unknown. (cdc.gov)
The relatively large number of pediatric cases in this outbreak enabled closer investigation of factors associated with increased survival of pediatric patients with EVD. (cdc.gov)
The shortage of available organs was previously most acute for pediatric patients. (medscape.com)
Because of the small number of pediatric donors, the mortality rate among patients on the wait list was commonly high when only whole-organ transplantation was performed. (medscape.com)
Over the following 30 years, the risk of death among patients on the pediatric wait list substantially declined because of the ability to use these reduced-size grafts and because of the subsequent introduction of live-donor transplantation. (medscape.com)
Given the high wait-list mortality rate among pediatric patients with end-stage liver disease and improved understanding of segmental liver anatomy, various techniques were developed to provide reduced-size allografts with complete arterial, portal, biliary, and venous drainage. (medscape.com)
No statistically significant differences were found between viral loads in adults and pediatric patients. (cdc.gov)
however, in the pediatric population, this difference did not reach statistical significance, likely because of the small sample size and the wide range of observed values in the pediatric patients with nonfatal cases. (cdc.gov)

In this randomised, double-blind, phase 3 trial, we recruited patients aged 18 years and older with glioblastoma from 165 hospitals in 22 countries. (nih.gov)
This controversy has become critical as multiple phase III trials of anti-VEGF agents combined with cytotoxics failed to show overall survival benefit in newly diagnosed glioblastoma (nGBM) patients and several other cancers. (mit.edu)

CONCLUSIONS: Neither disease-specific nor overall survival varied by region, suggesting geographically uniform assessments of risk in patient selection for radical prostatectomy. (laprp.com)

Although great progress has been made in diagnosis and treatment of CRC, global data demonstrated that the mortality was still unsatisfactory for CRC patients [ 2 ]. (biomedcentral.com)
Within 4 months of cancer diagnosis, surgery and radiation were received by 39% and 32% of study patients, respectively. (biomedcentral.com)
Reliable estimates of survival following a diagnosis of HF are important to guide management and facilitate advanced care planning. (biomedcentral.com)
Patients will often spend long periods of time in this chronic, stable phase of their illness, especially in the early stages following diagnosis and initial treatment. (biomedcentral.com)
The aim of this study was to evaluate the relationship between the monocyte count assessed at diagnosis and disease-free survival and prognosis in patients with esophageal cancer. (researchsquare.com)
The effect of monocyte count assessed in the blood samples taken at the time of diagnosis prior to the initiation of the treatment on disease-free survival was investigated. (researchsquare.com)
Given that the monocyte count at the time of diagnosis dynamically reflects the systemic inflammatory response to cancer, studies often measure monocyte count at the time of diagnosis in their patients. (researchsquare.com)
In the present study, we aimed to investigate whether the monocyte count measured at the time of diagnosis can be used as a new prognostic biomarker in predicting disease-free survival in patients with esophageal cancer. (researchsquare.com)
Neuropathological diagnosis was performed in accordance with the 2016 WHO classification and patients with a mutation encoding for the isocitrate dehydrogenase (IDH) were not included, since they most probably represented secondary GBM with a completely different prognosis [ 23 , 24 ]. (springer.com)
We compared patients who started HAART at the diagnosis of TB [simultaneous therapy (ST)] or not. (lww.com)
By univariate analysis, survival was also associated with no endovenous drug use and a later year of TB diagnosis. (lww.com)
When the diagnosis of hepatocellular carcinoma is being considered or if the diagnosis is confirmed, transfer the patient to a cancer institution. (medscape.com)
Among the total of 5,594 patients with NSCLC included in the analysis, 795 (14.2%) were never-smokers, 3,308 (59.1%) were former smokers, and 1,491 (26.7%) were current smokers at time of diagnosis. (ascopost.com)
Moreover, while the mainstay of the diagnosis of MHC-II deficiency is the absence of constitutive and inducible expression of MHC-II molecules on all cell types, other tests for T-cell function are less informative in such patients. (hindawi.com)

From the patient's point of view, mortality risk predicted percentage for an individual patient is more valuable and important than that for a special group. (biomedcentral.com)
2 ] The liver is the primary site for metastases for most malignancies of the gastrointestinal tract, accounting for a large proportion of the morbidity and mortality in those patients. (bcmj.org)
Regional and deprivation-specific life tables are built to adjust survival estimates for differences in background mortality. (bmj.com)

Table 1 Univariate Analysis of Disease Free Survival - 368 Eligible Patients. (biomedcentral.com)

The retrospective study included 145 patients with esophageal cancer who presented to Van Training and Research Hospital Medical Oncology outpatient clinic between January 2015 and September 2020. (researchsquare.com)

Patients with newly diagnosed primary GBM treated with the same therapeutical scheme between 2010 and 2015 in our institution were retrospectively reviewed. (springer.com)
We retrospectively analyzed 606 consecutive Chinese UTUC patients treated by RNU from 2000 to 2010. (hindawi.com)
We retrospectively analyzed 77 patients treated at our center between 1995 and 2013. (cancerindex.org)

Few studies have evaluated survival, treatment, resource use, and costs among women with stage IV ER + breast cancer (BC) who did not receive HER2 targeted therapy. (biomedcentral.com)
Systemic therapies are the recommended primary treatment option for patients with metastatic breast cancer, while surgery is generally considered, if appropriate, after initial systemic therapy [ 4 ]. (biomedcentral.com)
New molecular markers to predict the prognosis of endometrial cancer patients preoperatively should be found for individualization of treatment. (nih.gov)
Patients, investigators, and the trial funder were masked to treatment allocation. (nih.gov)
16 deaths in the study were caused by adverse events (nine [4%] in the rindopepimut group and seven [3%] in the control group), of which one-a pulmonary embolism in a 64-year-old male patient after 11 months of treatment-was assessed as potentially related to rindopepimut. (nih.gov)
Treatment of a fraction of the enrolled subjects with metformin may have introduced various selection biases. (medscape.com)
Treatment responses of patients with acute myeloid leukemia (AML) are known to be heterogeneous, posing challenges for risk scoring and treatment stratification. (nature.com)
Simultaneous HAART and TB treatment in HIV patients with TB is associated with improved survival. (lww.com)
The best time to begin antiretroviral treatment in patients with tuberculosis (TB) and HIV is controversial. (lww.com)
Following institutional review board approval and written informed consent from patients, we initially collected the clinicopathological data of 912 consecutive UTUC patients who received treatment in the Department of Urology, Peking University First Hospital, from 2000 to 2012. (hindawi.com)
The researchers reported PFS as well as overall survival and treatment-related toxic effects. (medscape.com)
The patients were not randomly assigned and the decision to give HIPEC was at the clinician's discretion, introducing the possibility of selection and treatment bias. (medscape.com)
A Cochrane database review of interventions for hereditary hemochromatosis found that phlebotomy remained the treatment of choice in those with hereditary hemochromatosis who required blood letting, but no data from randomized trials provided evidence of benefit from any form of blood letting in these patients. (medscape.com)
however, over this study period, 50.8% of patients discontinued AS and proceeded to definitive treatment, reported Antonio Finelli, MD, MSc, of the University of Toronto, and colleagues in the Journal of Urology . (medpagetoday.com)
Treatment-free survival with AS was 85% at 1 year, 63% at 2 years, 58% at 3 years, 55% at 4 years, and 52% at 5 years. (medpagetoday.com)
In an editorial comment accompanying the study, Michael S. Sessine, MD, and Jeffrey J. Tosoian, MD, MPH, both of the University of Michigan in Ann Arbor, noted that the 5-year treatment-free survival rate in the current study population was below the rates reported by prospective AS programs at Sunnybrook Health in Toronto and Johns Hopkins Medicine in Baltimore. (medpagetoday.com)
They suggested that the lower treatment-free survival rate in the current study could be attributed to initial undersampling. (medpagetoday.com)
Regardless, the new findings "have added to the growing body of AS literature and provided potential risk factors for treatment that can be used to better educate and counsel patients initiating AS. (medpagetoday.com)
During treatment at UCM, patients and their families may receive a discount at many Chicago hotels. (bethematch.org)
By using immune system, researchers are finding ways to improve treatment for patients with breast cancer brain metastases. (medindia.net)
End-stage kidney disease (ESKD) is the last stage of a chronic kidney disease, which if not addressed leads to premature death and, although it can be addressed by dialysis, kidney transplantation is the preferred treatment due to better survival rates, improved quality of life and cost efficiency. (europa.eu)
For the 40% of patients with a classical response, immunosuppressive side effects could be reduced by adjusting the treatment to the actual patient needs. (europa.eu)
Dr Grey's promising discovery during his Leukaemia UK John Goldman Fellowship, demonstrates the importance of continued research in this area and could go on to provide a vital new treatment option for leukaemia patients. (york.ac.uk)
Identifying prognostic factors of OS may help identify patients at high risk for close follow-up and guide treatment for selected patients. (biomedcentral.com)
An immunocompromised patient was nearly nine times more likely to die, while application of appropriate treatment reduced the risk (risk ratio 0.06). (bmj.com)
These drugs constitute the mainstay of treatment and knowledge of resistance is likely to be of direct benefit to the individual patient and to public health TB programmes. (bmj.com)
Surgical resection is the only known potentially curative treatment for patients with primary or metastatic liver tumors. (bcmj.org)
These findings could improve the discrimination of patients who would benefit from adjuvant treatment. (frontiersin.org)
Here we report a severe life-threatening complication of treatment with streptozotocin in a patient with pancreatic island-cell carcinoma. (cancerindex.org)
Segelman J, Singnomklao T, Hellborg H, Martling A. Differences in MDT assessment and treatment between patients with stage IV colon and rectal cancer. (cancercentrum.se)
Careful multidisciplinary assessment and treatment selection based on the probability of cure and preservation of function are of paramount importance in the treatment of these patients. (medscape.com)

3 ] found that a pyroptosis-related signature can effectively predict the prognosis of patients with ovarian cancer. (nature.com)

Results One-year relative survival improved for all cancers except cervical cancer. (bmj.com)
The reduction in geographical inequality in breast cancer survival may be followed by a similar trend for other cancers, provided government recommendations are implemented similarly. (bmj.com)

These results are not directly generalisable to patients in the stable, chronic phase of their condition. (biomedcentral.com)
These results may help guide policy making, developing quality indicators, and developing targeted continued education for physicians and patients embarking on AS to establish realistic expectations," Finelli and team wrote. (medpagetoday.com)
RESULTS: Forty-eight patients were included in the study: 24 with IBD and 24 with IIA occlusion. (lu.se)
Iliac branch devices are shown to be a valid alternative in highly selected cases, with good midterm results, even if reinterventions are required in a significant proportion of patients. (lu.se)
This center's actual 1-year survival results are similar to the expected rate for this center. (bethematch.org)
However, the results from the QUASAR and MOSAIC trials demonstrated no further benefit when adding OXA to 5-FU in stage II patients, even those at high risk. (frontiersin.org)
Data of 1664 patients , between 2004 and 2015, were extracted from the Surveillance , Epidemiology , and End Results database. (bvsalud.org)

Targets that have been identified as having the potential to improve survival in patients with castration-resistant prostate cancer stem from research in angiogenesis, bone metabolism, immunotherapy, androgen metabolism and receptor regulation, and apoptosis. (cancernetwork.com)

The objective of the current research was to develop and verify a Machine learning survival predictive system for CRC based on immune gene expression data and machine learning algorithms. (biomedcentral.com)
Three machine learning algorithms were used to create an Machine learning survival predictive system for CRC. (biomedcentral.com)
Adenosine-to-inosine RNA editing (ATIRE) is characterized as non-mutational epigenetic reprogramming hallmark of cancer, while little is known about its predictive role in cancer survival. (biomedcentral.com)
However, predictive markers for patient selection are still missing. (cancerindex.org)

3 ] Unfortunately, fewer than 30% of patients are candidates for curative surgical resection at the time of presentation because of disease burden or anatomical location of the metastases. (bcmj.org)
Patients may have bilateral palpable adenopathy because of the midline location and the high propensity for regional lymph node metastases. (medscape.com)

Surgical resection is necessary to conduct a pathological biopsy and to achieve a reduction of intracranial pressure in low-grade gliomas patients. (biomedcentral.com)
Immediately following successful REBOA deployment, patients must be considered for emergent surgical intervention. (wikipedia.org)
With only 30% of all CRC patients eligible for curative surgical resection, the six minimally invasive treatments discussed here bear close examination. (bcmj.org)
[ 9 ] The use of TAC as the primary immunosuppressant in small bowel transplantation as well as improved surgical techniques, the availability of an increased array of potent immunosuppressive medications, infection prophylaxis, and suitable patient selection have contributed to the reality of this procedure for a growing number of patients who are total parenteral nutrition (TPN)-dependent and have permanent intestinal failure. (medscape.com)

Our findings showed that monocyte count is a prognostic factor affecting disease-free survival in patients with esophageal cancer, regardless of histological subtype. (researchsquare.com)
In this study, we aimed to develop a convenient web-based calculator to predict the overall survival (OS) of patients with Stage I esophageal cancer (EC). (bvsalud.org)

Careful patient selection is advised for liver transplantation to treat patients with hepatocellular carcinoma. (medscape.com)
The study involved a series of 368 patients from the François Baclesse Cancer Centre (Caen) treated for a breast carcinoma between 1991 and 1995, whitout neoadjuvant therapy and with a follow-up of more than 15 years. (biomedcentral.com)
Streptozotocin-induced diabetic ketoacidosis in a patient with metastatic islet-cell carcinoma. (cancerindex.org)

Independent prognostic factors were determined by multivariate Cox regression analysis using a forward stepwise selection. (nih.gov)

A large proportion of patients who die from ischaemic heart disease die outside hospital in sudden death. (bmj.com)
They pointed out that these programs showed an increase in the proportion of patients remaining on AS over time, which was "likely the result of better initial patient selection (i.e., less undersampling), with more patients exposed to MRI and targeted biopsies during diagnostic and confirmatory testing. (medpagetoday.com)

Metformin associates with improved myocardial perfusion reserve and survival in patients with Type 2 Diabetes Mellitus," by researchers primarily affiliated with the University of Leeds, Leeds, UK, on medRxiv and provided to you by Medscape. (medscape.com)
Cite this: Metformin Ups Myocardial Perfusion and Survival in T2D - Medscape - May 09, 2023. (medscape.com)
We demonstrate that improved perfusion occurs only in a subset of patients in cediranib-containing regimens, and is associated with improved overall survival in these nGBM patients. (mit.edu)

Studies of acute HF or specific subgroups of patients will be excluded. (biomedcentral.com)
Special subgroups of patients might also benefit from BMV, including pregnant women, older patients with rigid valves, and those with mitral valve restenosis. (intechopen.com)

Multivariate analysis including number of positive PAN groups showed that LVSI, number of positive PAN groups were independent prognostic factors for survival. (nih.gov)
The influence of various extensively studied prognostic factors on survival was assessed by multivariate analysis. (springer.com)

As of October 24, 2023, according to the Organ Procurement and Transplantation Network , 10,227 patients were awaiting a liver transplant. (medscape.com)
Despite a steady increase of more than 30% in liver transplants per year since 2012, many patients continue to die while awaiting a life-saving transplant. (medscape.com)
For patient education information, see the Liver Transplant Directory . (medscape.com)
The use of liver biopsy in hereditary hemochromatosis can be restricted to those patients with a high probability of severe fibrosis or cirrhosis. (medscape.com)
[ 2 ] Nevertheless, extended survival was seen in a few patients and included a 3-year-old girl who received a multivisceral transplant (stomach, duodenum, pancreas, small bowel, colon and liver). (medscape.com)

Higher polygenic risk for melanoma is associated with improved survival in a high ultraviolet radiation setting. (cdc.gov)

Most existing research has focused on survival rates for patients admitted to hospital with acute HF. (biomedcentral.com)
Most previous studies of HF prognosis have focused on 'acute' HF and recruited patients who have been admitted to hospital following a recent deterioration in symptoms. (biomedcentral.com)
Recently, we analyzed serum biomarkers by using samples from the Gulu outbreak and identified associations between cytokines/chemokines, acute-phase reactants, makers of coagulopathy, and markers of endothelial function and patient death, hemorrhage, and viremia ( 10 ). (cdc.gov)

The term hemorrhagic fever has been used to describe this disease process because hemorrhagic manifestations develop in many patients during the course of illness. (cdc.gov)
In this study, we used a series of multiplex assays to measure the concentrations of 55 serum analytes in specimens from patients from the Gulu outbreak to identify biomarkers that had age-specific associations with survival, hemorrhagic manifestations, or both. (cdc.gov)
Current literature demonstrates a survival benefit of REBOA deployment in patients with severe hemorrhagic shock who do not require cardiopulmonary resuscitation (CPR). (wikipedia.org)
This selection was designed to be representative of overall sex ratios, hemorrhagic manifestations, and death rates observed during the outbreak. (cdc.gov)

Taking into account the vast variations in reported hospital survival, 5, 6 we believe that more attention must be paid to the "fifth link" to view a complete chain from early access to hospital discharge. (bmj.com)
The majority of persons who experience an OHCA event, irrespective of etiology, do not receive bystander-assisted cardiopulmonary resuscitation (CPR) or other timely interventions that are known to improve the likelihood of survival to hospital discharge (e.g., defibrillation). (cdc.gov)

Major indicators for an increased chance of survival were initial ventricular fibrillation/tachycardia, bystander cardiopulmonary resuscitation, arrest being witnessed, and the patient being conscious on admission. (bmj.com)

ABSTRACT The 5-year survival rate of female breast cancer cases in Jordan and some of the factors that affected survival were measured. (who.int)

The AASLD guidelines state hereditary hemochromatosis patients who have evidence of iron overload are "strongly encouraged" to receive phlebotomy regularly until iron stores are depleted. (medscape.com)
Patients with hereditary hemochromatosis may be asymptomatic (75%) or may present with general and organ-related signs and symptoms. (medscape.com)
C282Y homozygosity or compound heterozygosity C282Y/H63D is found in most patients with hereditary hemochromatosis. (medscape.com)

The National Comprehensive Cancer Network (NCCN) guidelines recommend all patients newly diagnosed with breast cancer be tested for hormone receptor status via expression of estrogen and/or progesterone receptors (ER/PR) and human epidermal growth factor receptor-2 (HER2) [ 4 ]. (biomedcentral.com)

The current study identified twenty prognostic immune genes for CRC patients and constructed an immune-related regulatory network. (biomedcentral.com)
As such, the immune system is prepared to reject a "foreign organ", something that is nowadays prevented by prescribing immunosuppressive therapies (drugs that suppress/reduce the effectiveness of the immune system) to the patients for their whole life. (europa.eu)
Patients were genotyped for a panel of 192 tagging polymorphisms in 34 immune-related genes. (frontiersin.org)

Variables associated with survival were included in a Cox proportional hazards model. (bmj.com)

Anatomy5

Organisms4

Diseases41

Chemicals and Drugs23

Analytical, Diagnostic and Therapeutic Techniques and Equipment126

Psychiatry and Psychology3

Phenomena and Processes44

Disciplines and Occupations6

Anthropology, Education, Sociology and Social Phenomena4

Humanities1

Information Science10

Health Care49

Geographicals2

Tumor24

Outcomes12

Methods5

Cohort11

Chemotherapy25

Kaplan-Meier4

Clinical22

Postoperative8

Metastasis6

Overall survival in patients1

Characteristics4

Prediction7

Absolute shrinkage and selection operator1

Significantly6

Increase survival4

Analyses2

Median survival2

Progression8

Recurrence3

Underwent3

Adjuvant therapy1

Colorectal cancer3

Disease-specific survival5

Adult7

Outcome8

Radiotherapy1

0.0011

Pediatric11

Glioblastoma2

Conclusions1

Diagnosis14

Mortality3

Univariate analysis1

Retrospective1

Retrospectively3

Treatment31

Predict the prognosis1

Cancers2

Results7

Improve survival in patients1

Predictive4

Metastases2

Surgical4

Esophageal cancer2

Carcinoma3

Regression1

Proportion of patients2

Perfusion3

Subgroups of patients2

Multivariate2

Liver5

Associated with improved survival1

Acute3

Hemorrhagic4

Hospital discharge2

Ventricular fibrillation1

Abstract1

Hereditary hemochromatosis3

Newly diagnosed with breast cancer1

Immune3

Proportional1