Surgically resected heterogeneous tumors adenocarcinoma. Medical search. Frequent questions

Heterogeneity in solid tumors is not limited to the differences between neoplastic cancer cells. (por-journal.com)

1,2 The true incidence of renal masses (including benign lesions) is unknown, but benign lesions comprise approximately 20% of surgically resected tumors. (ahrq.gov)
Like most gallbladder lesions, early-stage adenocarcinoma tends to present with symptoms similar to those of cholelithiasis or biliary dyskinesia. (medscape.com)
Comparison of surgically resected polypoid lesions of the gallbladder to their pre-operative ultrasound characteristics. (medscape.com)
In this cohort study of 94 patients with resected melanoma brain metastases that underwent targeted DNA sequencing, BRAF V600E variant lesions were associated with worse intracranial progression-free survival and overall survival. (cdc.gov)
Screening for the VISION trial using 177 Lu-PSMA-617 radioligand therapy (RLT) in metastatic castration-resistant prostate cancer excluded approximately 12% of patients due to missing or low PSMA expression of known tumor lesions in 68 Ga-PSMA11-PET [ 24 ]. (springeropen.com)

Overview of Lymphoma Lymphomas are a heterogeneous group of tumors arising in the reticuloendothelial and lymphatic systems. (msdmanuals.com)
Renal masses are a biologically heterogeneous group of tumors, ranging from benign masses, to indolent cancers that behave in a benign fashion, and finally, extremely aggressive and deadly cancers. (ahrq.gov)

No test is effective at screening for renal cell carcinoma, and most tumors are detected incidentally during an evaluation for unrelated or non-specific complaints. (ahrq.gov)

The 5 year disease-free survival (DFS) per tumor origin was: 94% for PMP-LG, 85% for PMP-HG, 100% for benign multicyst peritoneal mesothelioma (MPM), 37.4% for colonic origin, and 54%(at 3 years) for ovarian origin. (unav.edu)
Preoperative patient and tumor (imaging) characteristics are used to stratify the risk of benign versus malignant disease, and indolent versus aggressive cancers. (ahrq.gov)
Methods: Flow cytometric analysis of DNA pliody and S-Phase Fraction (SPF) was done in 50 fresh tumor tissue sections of SGTs which diagnosed as 15 benign and 35 malignant tumors. (researchgate.net)
Results: 93.3% of the benign SGTs tumors were diploid, while only 34% of malignant tumors were diploid and 66% were aneuploid. (researchgate.net)
The malignant SGTs had higher SPF than the benign tumors but with no significant difference. (researchgate.net)
Microcystic adenoma of the pancreas is a tumor that is benign in nature. (hindawi.com)

The purpose of this study was to measure the extent of hypoxia in microscopic melanoma xenografts and to search for possible mechanisms leading to the development of hypoxia in these tumors. (biomedcentral.com)
A-07, D-12, R-18, and U-25 human melanoma xenografts grown in dorsal window chambers or as flank tumors were used as preclinical tumor models. (biomedcentral.com)
Two of the four investigated melanoma models developed hypoxic regions in microscopic tumors, and the development of hypoxia was associated with poor vascular pericyte coverage and inadequate vascular function. (biomedcentral.com)
The hypoxic status of microscopic tumors was compared with the extent of hypoxia in macroscopic tumors of the same melanoma models. (biomedcentral.com)

Gastrointestinal stromal tumors (GISTs) account for less than 1% of GI tumors, but they are the most common mesenchymal neoplasms of the GI tract. (medscape.com)
Aim: The aim of this study is to investigate the DNA ploidy and S-Phase Fraction (SPF) of some Salivary Gland Tumors (SGTs) in Egyptian patients and to investigate the correlation between these two biological parameters and the presumptive behavior of these neoplasms. (researchgate.net)
Neuroendocrine neoplasms (NENs) include all tumors derived from the diffuse endocrine system. (springeropen.com)

Tumor location is a strong predictor of tumor progression and survival in T2 gallbladder cancer: an international multicenter study. (medscape.com)
In a number of human malignancies, tumor-associated macrophages (TAMs) are closely involved in tumor progression. (biomedcentral.com)
Macrophages that infiltrate tumor tissues are referred to as tumor-associated macrophages (TAMs) and are closely involved in tumor progression by inducing angiogenesis, immunosuppression, and invasion [ 1 ]. (biomedcentral.com)
Their exact origin and functions are not fully understood, but it is hypothesized that they can enhance tumor growth and progression, invasion, and metastatic potential as well [ 12 ]. (por-journal.com)
They are more heterogeneous than normal fibroblasts and express various surface receptors and cytokines that facilitate tumor progression, angiogenesis, etc. [ 13 ]. (por-journal.com)
Some of these cells have antitumoral behavior (NK cells, CD8 + T cells, CD4 + Th1 cells, and APCs), while others can promote tumor progression (CD4 + Th2 cells, regulatory T cells, and tumor-associated macrophages) [ 13 ]. (por-journal.com)
In 50-55%, pancreatic cancer has already metastasized, but in the remaining patients the tumor cannot be removed surgically due to local disease progression [ 5 , 6 ]. (biomedcentral.com)
Metastasis-associated in colon cancer-1 (MACC1) was first identified as a transcriptional activator for proto-oncogene c-MET expression, and its overexpression is frequently associated with metastatic progression for multiply tumor types. (biomedcentral.com)

Combination Therapy with a Bispecific Antibody Targeting the hERG1/β1 Integrin Complex and Gemcitabine in Pancreatic Ductal Adenocarcinoma. (unifi.it)
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a very dense and highly organized tumor microenvironment (TME) consisting of extracellular matrix (ECM) proteins, cancer-associated fibroblasts (CAFs), pancreatic stellate cells (PSCs), and immune cells. (mdpi.com)

PJS is autosomal-dominant condition caused by mutations of STK11, characterized by gastrointestinal polyposis, mucocutaneous pigmentation, and predisposition to a range of epithelial cancers: including colorectal, gastric, pancreatic, breast, ovarian cancers and sex cord tumors with annular tubules). (cancerindex.org)
5 The greatest increase in incidence was noted in small, clinically-localized tumors (i.e. tumors within the kidney with no evidence of local spread, lymph node involvement or distant metastases), now upwards of 40% of all kidney cancers. (ahrq.gov)
9, 10 Importantly, approximately 40% of clinically localized tumors are determined to be locally-advanced cancers (stage T3, with invasion of perinephric fat or venous structures) at pathological examination. (ahrq.gov)
11 Locally advanced cancers have a significantly worse prognosis than localized tumors. (ahrq.gov)
It focuses on how precision oncology has shaped advances in the impact of non-coding RNAs in epigenetics and cancer, immunotherapy and tumor biology, and the clinical significance of various therapies in a range of cancers. (biomedcentral.com)
In this review article we aimed to emphasize the importance of single-cell analyses by presenting tumor heterogeneity and the limitations of conventional investigational approaches, followed by an overview of the whole single-cell analytic workflow from sample isolation to amplification, sequencing and bioinformatic analysis and a review of recent literature regarding the single-cell analysis of colorectal cancers. (por-journal.com)

The malignant tumours consisted of 18 adenoid cystic adenomas, 10 mucoepidermoid carcinomas, 5 acinic cell carcinomas, 5 carcinoma in pleomorphic adenoma as well as of 12 other malignancies belonging to 7 different tumour entities. (researchgate.net)
There was no significant correlation of ploidy status or SPF with the tumor grades of mucoepidermoid carcinomas. (researchgate.net)
We examined 69 samples of surgically resected thymic epithelial tumors, namely, 16 thymic carcinomas and 53 thymomas, in which we immunohistochemically evaluated the presence of TAMs using CD68 and CD163 as markers and DCs using S100 as the marker in tumor tissue samples in comparison with normal thymic tissues. (biomedcentral.com)

Gastric neuroendocrine tumors, unlike those of the small intestine, can be managed with endoscopic resection if they are small and associated with chronic atrophic gastritis (eg, type 1 disease). (msdmanuals.com)
Shown here is a gastric gastrointestinal stromal tumor (GIST). (medscape.com)

Nowadays, with single-cell approaches, tumor heterogeneity, the tumor microenvironment, and the interplay between tumor cells and their surroundings can be described in unprecedented detail. (por-journal.com)

The prognostic implication of histopathologic subtyping of pulmonary adenocarcinoma according to the classification of the World Health Organization. (wikipedia.org)
Prognostic significance of the tumor-stroma ratio in gallbladder cancer. (medscape.com)
Although it has been shown that histologic subtypes can be used to stratify surgically resected patients into prognostic groups, its value in determining the survival benefit of chemotherapy has yet to be established. (amegroups.org)

It is possible to cure gallbladder cancer when tumors are treated surgically at an early stage. (medscape.com)

Overview of Carcinoid Tumors Carcinoid tumors develop from neuroendocrine cells in the gastrointestinal tract (90%), pancreas, pulmonary bronchi, and rarely the genitourinary tract. (msdmanuals.com)
Carcinoid Syndrome Carcinoid syndrome develops in some people with carcinoid tumors and is characterized by cutaneous flushing, abdominal cramps, and diarrhea. (msdmanuals.com)
Several molecular alterations found in carcinoid tumors might act as molecular targets leading to development of new therapeutic options. (springeropen.com)

Studies of macroscopic experimental tumors have shown that the severity of the vascular abnormalities increases during tumor growth, resulting in reduced blood supply and increased extent of hypoxia [ 8 ]. (biomedcentral.com)

Acinar adenocarcinomas are the most common form of prostate gland malignancy. (wikipedia.org)
3, 16-18 The best predictors of malignancy are male sex and tumor size, although computed tomography (CT) enhancement patterns have also been able to predict histology in up to 85% of cases. (ahrq.gov)
Conclusion: DNA aneuploidy may be a key indicator for tumors activity and malignancy in SGTs, while the SPF has a minor role in the evaluation of SGTs activity. (researchgate.net)
Such tumor profiles can subsequently be applied to exclusively tailor cancer therapies to directly target a causative mutation for a malignancy, ultimately achieving a personalized and precise approach to cancer treatment. (biomedcentral.com)

Adenocarcinoma ("adeno" = "gland", "carcinoma" = cancer of epithelium) is the most common type of lung cancer in the U.S., Japan, and most of Western Europe, although it is the second most common form in Eastern parts of Europe (after squamous cell carcinoma). (wikipedia.org)
Another change is the subclassification of adenocarcinoma: the definition of bronchioalveolar carcinoma has been restricted to noninvasive tumours. (ersjournals.com)
As compared to the previous edition, changes include a better definition of pre-invasive lesion, a reclassification of adenocarcinoma, the description of two new tumour types as variants of large cell carcinoma, large cell neuroendocrine carcinoma (LCNEC) and basaloid carcinoma, and a new class called pleomorphic carcinoma. (ersjournals.com)
[ 3 , 4 ] The term "pseudomesotheliomatous carcinoma" was first applied by Harwood and colleagues in 1976 to 6 cases of peripheral lung adenocarcinoma that closely mimicked mesothelioma. (medscape.com)
Non-small-cell lung cancer (NSCLC), which primarily comprises lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC), is the major type of primary lung cancer [ 2 ]. (biomedcentral.com)
Hepatocellular carcinoma (HCC) one of the most common digestive system tumors, threatens the tens of thousands of people with high morbidity and mortality world widely. (biomedcentral.com)
revealed for the first time carcinoma ex microcystic adenoma in which the tumor, without metastases, showed inherent malignant changes [ 7 ]. (hindawi.com)
Thymic epithelial tumors are rare mediastinal tumors and can be classified into thymoma and thymic carcinoma. (biomedcentral.com)
Here, we immunohistochemically examined tumor tissue samples to characterize TAMs and DCs in thymoma and thymic carcinoma by comparing them with those in normal thymic tissues. (biomedcentral.com)
Primary tumor material (P) derived from patients undergoing surgery for head and neck squamous cell carcinoma (HNSCC) or glioblastoma multiforme (GBM) was transplanted subcutaneously into NMRI Foxn1 nu/nu mice. (europdxworkshop.eu)

Similarly, small rectal neuroendocrine tumors sometimes can be removed endoscopically. (msdmanuals.com)
For metastatic neuroendocrine tumors, long-acting somatostatin analog therapy with dose escalation, peptide receptor radioligand therapy (PRRT) using a radiolabeled somatostatin analog, or everolimus can be used to effectively control the disease. (msdmanuals.com)
There has been substantial evolution of concepts in neuroendocrine lung tumour classification. (ersjournals.com)

OBJECTIVES: To evaluate the expression of COX-2 and HER2 and determine their correlation with clinicopathologic parameters in surgically resected histologically diagnosed cases of colorectal cancer. (bvsalud.org)

Survival is significantly better in patients whose tumors are well differentiated (i.e. the glands and/or tubules are more completely developed) than when poorly differentiated (i.e. with rudimentary glands). (wikipedia.org)
Recent research has classified lung adenocarcinoma patients with KRAS mutation into three subtypes by co-occurring genetic events in TP53 (KP subgroup), STK11/LKB1 (KL subgroup) and CDKN2A/B inactivation plus TTF-1 low expression (KC subgroup). (cancerindex.org)
In patients with Crohn disease involving the small-bowel, the tumors tend to occur distally and in bypassed or inflamed loops of bowel. (msdmanuals.com)
Tumour-associated activating mutations in EGFR can identify patients with NSCLC who are likely to have a good response to TKIs. (bmj.com)
Recent developments in technology may make the monitoring of changes in patients' tumour genotypes easier in clinical practice, which may enable patients' treatment regimens to be tailored during the course of their disease, potentially leading to improved patient outcomes. (bmj.com)
Demographic, clinical and imaging characteristics are used to risk-stratify patients, and nomograms exist that combine these characteristics into composite models to classify tumors preoperatively. (ahrq.gov)
Wall-invasion pattern correlates with survival of patients with gallbladder adenocarcinoma. (medscape.com)
To define the incidence and characteristics of Lynch syndrome-related small-intestinal adenocarcinomas, meticulous familial and clinical histories were obtained from 195 patients with small-intestinal adenocarcinoma, and MMR protein immunohistochemistry, microsatellite instability, MLH1 methylation, and germline mutational analyses were performed. (oncotarget.com)
Small-intestinal adenocarcinomas were the first clinical manifestation in 37% (3/8) of Lynch syndrome patients, and second malignancies developed within 5 years in 63% (5/8). (oncotarget.com)
Clinical studies have shown that patients with highly hypoxic tumors have increased frequency of locoregional treatment failure, increased incidence of distant metastases and poor disease-free and overall survival rates following radiation therapy alone or radiation therapy combined with surgery and/or chemotherapy [ 1 ]. (biomedcentral.com)
This may be due to late diagnosis of these tumors in our patients as most cases diagnosed at advanced stage and the sections were taken from deep tumor tissue to increase the number of tumor cells in our samples. (researchgate.net)
Despite recent progress and development of surgical techniques and minimally invasive approaches, approximately 40% of lung ADC patients experience tumor recurrence and death following complete resection ( 3 , 4 ). (amegroups.org)
Solid predominant tumors are associated with higher incidence of early recurrence at distant sites in addition to having worse prognosis among stage I lung ADC patients ( 10 ). (amegroups.org)
In this study, we examined samples from 69 patients diagnosed and treated for primary thymic epithelial tumors at Showa University Northern Yokohama Hospital, Showa University Hospital, and Showa University Fujigaoka Hospital from August 2003 to June 2014. (biomedcentral.com)
Salivary Gland Polymorphous Adenocarcinoma: Clinicopathological Features and Gene Alterations in 36 Japanese Patients. (nagoya-u.ac.jp)
Typically, in patients older than 40 years, the ribs at the incision site are resected at the costovertebral angle to prevent rib fractures. (radiologykey.com)
Despite the fact that previous reports have already indicated variability in the judgement of tumor contact to defined anatomic structures, the consensus in judging resectability by pancreatic surgeons has not been evaluated in a large cohort of locally advanced or borderline resectable patients [ 14 ]. (biomedcentral.com)
Statistical analysis showed a significant correlation of MACC1 expression with the primary tumor, lymph node metastasis, distant metastasis classifications as well as the clinical staging in breast cancer patients. (biomedcentral.com)
Metastasis-associated in colon cancer-1 (MACC1) was first identified to be overexpressed in primary and metastatic tumor specimens of colon cancer as compared to normal colon mucosa and was found to be indicative of metastasis as well as poor survival of the patients. (biomedcentral.com)
Over the past decade, the oncology community has witnessed a revolution in our understanding of the biology of lung cancer with the identification of a significant proportion of patients whose tumors harbor targetable molecular changes. (gotoper.com)
To identify specific markers of CRT response, we compared pretreatment biopsies from LACC patients with pathological complete response (sensitive) with those from patients showing macroscopic residual tumor (resistant) after neoadjuvant CRT, using a proteomic approach integrated with gene expression profiling. (biomedcentral.com)
We recruited 889 surgically treated patients from two medical centers. (e-crt.org)
Current staging systems such as Barcelona Clinic Liver Cancer (BCLC) and 7th American Joint Committee on Cancer (AJCC) cannot accurately predict recurrence and survival, because the individual prognosis is affected by various risk factors including patients' general condition and their tumor characteristics whereas these systems only considered limited variables. (e-crt.org)

In China, which has the largest number of smokers and lung cancer cases in the world, the acinar tissue architectural pattern is by far the most common histological subtype of adenocarcinoma, comprising about 40% of all adenocarcinomas, and its incidence has increased significantly in recent decades. (wikipedia.org)

Acinar adenocarcinoma is a histological subtype of gland-forming cancer that is diagnosed when cuboidal and/or columnar shaped malignant cells in the neoplastic tissue form acini and tubules. (wikipedia.org)
The aim of this study was to identify valuable biomarkers by searching the candidate molecules that contribute to lung adenocarcinoma pathogenesis, especially KC subtype. (cancerindex.org)
REG4, an important regulator of gastro-intestinal carcinogenesis, was highly expressed in KRAS mutant lung adenocarcinoma with low expression of TTF-1 (KC subtype). (cancerindex.org)
The most common histologic subtype is adenocarcinoma (ADC), which accounts for approximately 50% of NSCLCs ( 3 , 4 ). (amegroups.org)

Malignant transformation in the tumor with metastases is rare and only about 26 cases have been reported so far. (hindawi.com)

Tumor hypoxia is a consequence of inadequate oxygen supply caused by extensive abnormalities in the vascular network [ 2 ]. (biomedcentral.com)
To search for mechanisms for the development of hypoxia, the morphology and function of the tumor vascular networks were studied with intravital microscopy and immunohistochemistry, and the expression of several angiogenesis-related genes was measured with quantitative PCR. (biomedcentral.com)

Malignant transformation of cystic adenomas of the pancreas was first described in 1989 wherein the tumor showed invasion into surrounding structures and into the liver [ 4 ]. (hindawi.com)
This is due to invasion or contact of the tumor to peripancreatic vessels [ 7 ]. (biomedcentral.com)
According to ISGPS definitions, the tumor contact to the celiac trunk, more than 180° abutment to the superior mesenteric artery, infiltration of the inferior vena cava, unreconstructable superior mesenteric vein or occlusion of the portal vein, or aortic invasion or encasement are considered signs of locally advanced pancreatic cancer [ 12 ]. (biomedcentral.com)
However, tumor cells can evade host's immune surveillance using a number of protective mechanisms, including downregulation of MHC-I molecules, secretion of anti-inflammatory cytokines, in other words, TGF-β and IL-10, secretion of immunosuppressive factors, VEGF, upregulation of PD-L1 and downregulation of co-stimulatory molecules thereby preventing activation of T cells, resulting in cancer invasion. (studylib.net)

A number of techniques have been employed for genotypic assessment of tumour-associated DNA to identify EGFR mutations, each of which has advantages and disadvantages. (bmj.com)
While current testing in most centers is charac-terized by a combination of several different single-gene or multiplex diagnostic assays, the advent of next-generation sequencing has provided a means of interrogating mutations, rearrangements, and copy number changes across a variety of therapeutically relevant oncogenes and tumor suppressor genes in a single test. (gotoper.com)

Tumour classification systems provide the foundation for tumour diagnosis and patient therapy and a critical basis for epidemiological and clinical studies. (ersjournals.com)
A meticulous patient history taking, MMR protein immunolabeling, and germline MMR gene mutational analysis are important for the diagnosis of Lynch syndrome-related small-intestinal adenocarcinomas. (oncotarget.com)

Microvessels, pericytes, and the extent of hypoxia were assessed by immunohistochemistry in microscopic tumors by using CD31, αSMA, and pimonidazole as markers, and the extent of radiobiological hypoxia was assessed in macroscopic flank tumors. (biomedcentral.com)
Macroscopic R-18 and U-25 tumors showed extensive hypoxia, whereas macroscopic A-07 and D-12 tumors were less hypoxic. (biomedcentral.com)

Mechanistic investigations demonstrated the key role of the identified genes in the balance between death and survival of tumor cells. (biomedcentral.com)
Notably, surgical treatment has also the potential advantage of removing chemoradioresistant residual tumor foci, with a higher local control and possibly better survival, since resistance of cancer cells to CRT remains a major therapeutic drawback. (biomedcentral.com)

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. (cancerindex.org)

The 5-year DFS per tumor origin was: 96% for perforated low grade appendiceal mucinous neoplasm (LAMN II) and 68.1% for colon origin. (unav.edu)
Tumors of the pancreas that contain substantial cystic components include mainly mucinous cystic neoplasm, intraductal papillary mucinous neoplasm, solid pseudopapillary tumor, and cystadenomas (which encompass microcystic, macrocystic/oligocystic, and rare solid serous adenomas). (hindawi.com)

Due to the heterogeneous nature of tumors, molecular profiling is crucial to our understanding of how genomics plays a role in the cause or development of an individual cancer. (biomedcentral.com)
In recent years, the evolution of the molecular biological technical background led to the widespread application of single-cell sequencing, a versatile tool particularly useful in the investigation of tumor heterogeneity. (por-journal.com)
Breast cancer is a heterogeneous disease with a variety of different molecular subtypes and varied clinical outcomes. (biomedcentral.com)

Studies investigating the oxygenation status and the development of hypoxia in microscopic tumors are sparse. (biomedcentral.com)
Studies investigating the development of hypoxia in microscopic tumors are sparse, but the extent of hypoxia has been measured in microscopic HT29 and HCT-8 colorectal adenocarcinoma xenografts [ 9 ]. (biomedcentral.com)
Afterwards, tumors at a volume of 0,12 cm³ were randomly allocated in the treatment groups of graded single doses under clamp blood flow conditions inducing homogenous hypoxia. (europdxworkshop.eu)

Ultrasonographic image of a heterogenous soft tissue mass (arrows) with a pocket of anechoic fluid (arrowheads) in the caudal abdomen of a doe, bordered cranially by peritoneal fluid (asterisk). (avma.org)
Pre-treatment tumor tissue biopsies were obtained during staging procedures, the joint assessment by surgeon and pathologist allowing an unequivocal identification of tumor area to be sampled. (biomedcentral.com)

Low-grade tumors may recur and infiltrate adjacent structures. (medscape.com)
On the other hand, dendritic cells (DCs) that infiltrate tumor tissues are involved in tumor suppression. (biomedcentral.com)

PDX models are an important tool to develop novel strategies against drug-and/or radio-resistant tumors in preclinical trials. (europdxworkshop.eu)

Treatment of rectal cancer often consists of surgical resection of the tumor. (stanford.edu)

However, there have been very few reports on the distribution profiles of TAMs and DCs in thymic epithelial tumors. (biomedcentral.com)

These tumors are managed expectantly and surgical management is considered only when the patient becomes symptomatic [ 2 ]. (hindawi.com)
Pedicle flaps are more commonly used in thoracic tumor resections because the surgical procedure is less complex and postoperative perfusion is more reliable. (radiologykey.com)

An international system of tumour classification is important for consistency in patient treatments and to provide the basis of epidemiological and biological studies. (ersjournals.com)

The distinction among these various tumors is important both clinically and epidemiologically. (medscape.com)

The majority of invasive ADCs are heterogenous with several histologic subtypes presenting simultaneously ( 7 ). (amegroups.org)

In Europe, acinar adenocarcinoma may comprise the dominant architectural pattern in as many as 50-60% of all adenocarcinomas. (wikipedia.org)

Chest wall surgery aims to resect the lesion with margins wide enough to eradicate the disease, while at the same time leaving a defect that can be closed effectively. (radiologykey.com)

An in-depth understanding of immune evasion mechanisms in tumors is crucial to overcome resistance and enable innovative advances in immunotherapy. (biomedcentral.com)

Microcystic adenoma of the pancreas is a rare tumor that presents indolently with features of slow growth and abdominal pain secondary to mass effect. (hindawi.com)
Gross section of an adenocarcinoma of the pancreas measuring 5 X 6 cm resected from the pancreatic body and tail. (medscape.com)
Resectability and the degree of abutment of the tumor to the venous and arterial structures adjacent to the pancreas were reported. (biomedcentral.com)

Heterogeneous intra-patient PSMA-ligand uptake was observed, and no significant correlation was present between the degree of heterogeneity of PSMA expression and PSMA-ligand uptake. (springeropen.com)

Many tumors have been described to have marked immune cell infiltration. (por-journal.com)

In each case, the clinical presentation, location of the tumour, and the outcome for the patient were studied. (bmj.com)

Larger or central tumors are more likely to be invasive, but small peripheral tumors may also be invasive. (ahrq.gov)

Anatomy19

Organisms6

Diseases103

Chemicals and Drugs42

Analytical, Diagnostic and Therapeutic Techniques and Equipment58

Phenomena and Processes30

Disciplines and Occupations1

Information Science4

Health Care15

Solid Tumors1

Lesions5

Group of tumors2

Renal cell carc1

Benign6

Melanoma4

Neoplasms3

Progression8

Ductal Adenocarcinoma2

Cancers6

Carcinomas3

Gastric2

Microenvironment1

Prognostic3

Gallbladder cancer1

Carcinoid3

Increases durin1

Malignancy4

Carcinoma10

Neuroendocrine3

Colorectal cancer1

Patients23

Incidence1

Subtype4

Metastases1

Vascular2

Invasion4

Mutations2

Diagnosis2

Macroscopic2

Survival2

Suppressor1

Mucinous neoplasm2

Molecular3

Hypoxia3

Tissue2

Infiltrate2

Preclinical1

Resection1

Epithelial1

Surgical2

Classification1

Clinically1

Histologic1

Comprise1

Lesion1

Immunotherapy1

Pancreas3

Correlation1

Infiltration1

Clinical presentation1

Peripheral1