• Perioperative Cost Analysis of Minimally Invasive vs Open Resection of Intradural Extramedullary Spinal Cord Tumors. (rush.edu)
  • Minimally invasive resection of intradural-extramedullary spinal neoplasms. (backbonejournal.com)
  • Here, the authors describe a 50-year-old male with an aggressive ENB, initially treated with resection and chemotherapy/radiation, who developed multiple thoracic and lumbar spinal metastases. (thejns.org)
  • She underwent tumor resection eight times due to the recurrence of spinal tumor in the same region in nine years. (balkanmedicaljournal.org)
  • CONCLUSION: Surgical resection significantly improves overall survival in patients with spinal chondrosarcoma. (providence.org)
  • Complete en bloc radical resection with postoperative radiation therapy is currently considered the gold standard. (surgicalneurologyint.com)
  • OBJECTIVES: Spinal deformity is a common development after laminectomy and resection of pediatric intramedullary spinal cord tumors. (duke.edu)
  • Brown-Sequard syndrome (BSS) is most commonly seen in patients with spinal trauma and extramedullary spinal neoplasm. (easychair.org)
  • Intradural extramedullary spinal neoplasms: Radiologic-pathologic correlation. (msdmanuals.com)
  • Metastatic lesions are responsible for about 85% of neoplastic spinal cord compression cases, with the other 15% due to primary neoplastic lesions of the spine. (medscape.com)
  • Metastatic lesions that involve the spinal cord affect about 5-10% of patients with cancer. (medscape.com)
  • Metastatic lesions are featured in this discussion since they cause 85% of the cases of neoplastic spinal cord compression. (medscape.com)
  • [ 3 ] Approximately 15% of all primary CNS lesions arise from the spinal cord, with an estimated incidence rate of 0.5-2.5 cases per 100,000 population. (medscape.com)
  • Contrast-enhanced sagittal computed tomography (CT) scan images demonstrate an area of decreased attenuation within vertebrae, with destructive or lytic lesions in the bone and spinal cord compression at that level. (spinalsurgerynews.com)
  • She underwent disease reevaluation 4 weeks after the completion of radiation, which showed improvement in the spinal tumor and no new metastatic lesions. (surgicalneurologyint.com)
  • Extra-spinal myxopapillary ependymoma is very rare, but it must be considered in the differential diagnosis of pelvic mass lesions. (balkanmedicaljournal.org)
  • Doug gave me more details on the upcoming book in a recent email: "The book is divided into four parts: I Neoplasms, II Non-neoplastic Mass Lesions, III Biopsies for non-neoplastic diseases not presenting as a mass, and IV Epilepsy Pathology. (blogspot.com)
  • 8 ] Our review of 13 patients over the past 10 years, revealed 38.46% cranial, 46.15% spinal, and 15.38% sacral lesions. (surgicalneurologyint.com)
  • Neuropathologists diagnose brain and spinal cord lesions removed at surgery and at autopsy. (duke.edu)
  • 1) Background: Surgery for spinal metastases has gained a decisive role in modern oncological treatment. (scite.ai)
  • Preliminary clinical experience with CFR-PEEK implants for spinal metastases exists. (scite.ai)
  • 2) Methods: We retrospectively analyzed prospectively the collected data of consecutive patients being operated on from 1 August 2015 to 31 October 2021 using a CFR-PEEK pedicle screw system for posterior stabilization because of spinal metastases or primary bone tumors of the spine. (scite.ai)
  • BACKGROUND: Spinal metastases are being diagnosed more frequently because of increasing life expectancies and advances in the diagnosis and therapy of primary tumours. (iospress.com)
  • OBJECTIVE: This aim of this study was to assess the quality of life (QoL) and functional outcomes after surgical intervention for s pinal metastases in a large cohort. (iospress.com)
  • CONCLUSION: Short-term and long-term improvements in functional outcomes and QoL were observed after surgical treatment of spinal metastases. (iospress.com)
  • Although ENBs often recur and have an aggressive clinical course, spinal metastases are extremely rare and the underlying molecular mechanisms are poorly understood. (thejns.org)
  • The authors performed targeted exome sequencing on both the resected primary tumor and biopsied spinal metastases, which revealed 12 total variants of unknown clinical significance in genes associated with the PI3K/AKT/mTOR pathway, chromatin remodeling, DNA repair, and cell proliferation. (thejns.org)
  • OBJECTIVE: Spinal chondrosarcomas are rare primary malignant neoplasms composed of cartilage-producing cells. (providence.org)
  • The World Health Organization considers these to be malignant neoplasms. (surgicalneurologyint.com)
  • Heterotopic ossification has also been observed in non-traumatic conditions (e.g., infections of the central nervous system, peripheral neuropathy, tetanus, biliary cirrhosis, Peyronie's disease, as well as in association with a variety of benign and malignant neoplasms). (nih.gov)
  • Clinical Management of Swallowing Disorders, Fourth Edition examines the diagnosis and treatment of swallowing disorders in children and adults and emphasizes team management, swallowing safety, nutrition, behavioral treatments, and surgical options. (pluralpublishing.com)
  • Dr. Nael's clinical and research interests include advanced imaging, quantitative neuroimaging, and multiparametric imaging approach in diagnosis of variety of cerebrovascular disorders and brain and spinal neoplasms. (uclahealth.org)
  • You plan to perform a hemilaminectomy procedure and want to evaluate the evidence behind whether computed tomography (CT) is a reliable modality in comparison to magnetic resonance imaging (MRI) for the diagnosis and surgical planning of thoracolumbar disc extrusions in dogs. (veterinary-practice.com)
  • The first step towards diagnosis and therapy is recognizing that the patient has some sort of spinal cord pathology. (emcrit.org)
  • Imaging Diagnosis Management: Cervical spinal trauma & radiographic variants simulating disease Cervical spine Arthritis Neoplasms Infection Post-Surgical cervical spine Cranio-cervical and upper cervical stability is dependent on transverse, superior and inferior bands of the C1-C2 ligament, alar ligaments, along with a few other ligaments Cervical Trauma The C/S is vulnerable to injury. (elpasochiropractorblog.com)
  • Under the diagnosis of uterine neoplasm, we carried out radical hysterectomy, omentectomy and pelvic lymphadenectomy as the surgical procedure. (balkanmedicaljournal.org)
  • Apply a state-of-the-art, integrated approach to brain cancer diagnosis and staging with Advances in Surgical Pathology: Brain Cancer. (libreriacortinamilano.it)
  • Myelopathy is a clinical diagnosis with localization of the neurological findings to the spinal cord, rather than the brain or the peripheral nervous system, and then to a particular segment of the spinal cord. (bvsalud.org)
  • Compression, trauma or other damage to this region of the spinal canal can result in cauda equina syndrome. (wikipedia.org)
  • Most common causes include as a complication of lumbar punctures, burst fractures resulting in posterior migration of fragments of the vertebral body, severe disc herniations, spinal anaesthesia involving trauma from catheters and high local anaesthetic concentrations around the cauda equina, penetrating trauma such as knife wounds or ballistic trauma. (wikipedia.org)
  • Spinal cord and soft-tissue injuries are best evaluated by magnetic resonance imaging, or MRI, whereas computed tomography scanning, or CT scans, best evaluate spinal trauma or spine fracture. (elpasochiropractorblog.com)
  • Heterotopic ossification may occur for no known reason as in myositis ossificans progressiva or may follow a wide variety of surgical, occupational, and sports trauma (e.g., hip arthroplasty, spinal cord injury, head injury, burns, and severe thigh bruises). (nih.gov)
  • As the director of Spine Surgery for the Department of Neurosurgery at the University of Maryland, I see a large volume of patients with spinal deformity, degenerative disease, spinal oncology and spine trauma. (umaryland.edu)
  • Anterior stabilization of three-column thoracolumbar spinal trauma. (umaryland.edu)
  • Socio-demographic parameters, circumstances and times of onset of trauma, mode of transport, state of consciousness, sensory and motor deficit, American Spinal Injury Association (ASIA) Score, hemodynamic and respiratory status were assessed. (bvsalud.org)
  • Extramedullary tumors may be intradural (meningiomas and schwannomas), which account for 60% of all primary spinal cord neoplasms, or extradural (metastatic tumors from breasts, lungs, prostate, leukemia, or lymphomas), which account for 25% of these neoplasms. (health-care-clinic.org)
  • OBJECTIVE: To investigate the feasibility and safety of minimally invasive surgery (MIS) for primary intradural spinal tumors. (neurosurgery-blog.com)
  • METHODS:Medical charts of 83 consecutive patients treated with MIS for intradural spinal tumors were reviewed. (neurosurgery-blog.com)
  • CONCLUSION: This study both demonstrates that it is feasible and safe to remove select, primary intradural spinal tumors using MIS, and augments the previous literature in favor of MIS for these tumors. (neurosurgery-blog.com)
  • Both intradural and extradural tumors exert their effects by compressing the spinal cord and its roots, rather than by invading the parenchyma. (msdmanuals.com)
  • Intradural extramedullary tumors may be painful when the nerve roots are compressed but can develop painlessly if the spinal cord is directly compressed without involving the root. (msdmanuals.com)
  • For the emergency physician, however, the cell origin of the tumor is less of a concern than the consequent syndromes of spinal cord dysfunction. (medscape.com)
  • The severity of spinal cord compromise secondary to a tumor spans a wide range. (medscape.com)
  • Some factors such as individual treatment strategy, according to the histology of the primary tumor, plan of treatment strategies carried out in a multidisciplinary manner, risk-benefit of radiotherapy, assessment of the degree of spinal instability, improvement in communication and referral between specialists in oncology showed an increase in the survival of these patients. (bvsalud.org)
  • En bloc spondylectomy with chemotherapy postoperatively constituted the treatment of choice for this tumor. (nel.edu)
  • Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive neoplasm of the central nervous system that generally arises intracranially in patients under 2 years of age. (surgicalneurologyint.com)
  • Atypical teratoid/rhabdoid tumor (AT/RT) is an aggressive neoplasm that constitutes approximately 6% of pediatric central nervous system (CNS) tumors. (surgicalneurologyint.com)
  • Is perioperative blood transfusion associated with postoperative thromboembolism or infection after metastatic spinal tumor surgery? (elsevierpure.com)
  • Part I is further divided into brain and spinal cord sections, and then of course individual chapters cover the gamut of tumor types. (blogspot.com)
  • Scholars@Duke publication: The role of concurrent fusion to prevent spinal deformity after intramedullary spinal cord tumor excision in children. (duke.edu)
  • Of these, 52 patients with a biopsy-proven intramedullary spinal cord tumor had complete clinical records and radiographic data. (duke.edu)
  • CONCLUSIONS: In the surgical treatment of patients with intramedullary spinal cord tumors, those that undergo instrumentation or in situ fusion at the time of spinal cord tumor excision are significantly less likely to develop postresection spinal deformity. (duke.edu)
  • Spinal cord tumors usually require decompression or radiation. (health-care-clinic.org)
  • If the patient has incomplete paraplegia of rapid onset, emergency surgical decompression may save cord function. (health-care-clinic.org)
  • Sudden onset is regarded as a medical emergency requiring prompt surgical decompression, with delay causing permanent loss of function. (wikipedia.org)
  • In cancer patients with clinical suspicion of spinal cord compression, dexamethasone should be initiated followed by surgical decompression, when possible, and radiation. (elsevierpure.com)
  • A 40-year-old woman with a C3-C4 spinal chordoma was optimally managed with a combined anterior/posterior surgical approach including decompression/fusion. (surgicalneurologyint.com)
  • Our objective is to compare the occurrence of postlaminectomy spinal deformity in children with intramedullary spinal cord tumors that underwent decompression with fusion at the time of surgery to those that did not undergo fusion. (duke.edu)
  • Altogether, in 8 patients, imaging findings influenced or changed clinical decisions and surgical planning. (ajnr.org)
  • Imagine this clinical scenario: you are presented with a Dachshund with acute onset paraplegia that you suspect has an intervertebral disc extrusion between the T3 and L3 spinal cord segments. (veterinary-practice.com)
  • The aim of this study was to characterize the radiologic presentation of patients with neurofibromatosis type 1 with widespread spinal disease and to correlate it to clinical presentation and outcome. (ajnr.org)
  • Here we report a case of 4th cervical spine involvement, and discuss the clinical picture, radiological findings and surgical procedure. (spinalsurgerynews.com)
  • The first five chapters deal with spinal tumors, either primary or metastatic, giving the reader a clear clinical review of the disease and its pathophysiology, as well as therapeutic options. (novapublishers.com)
  • His clinical practice includes surgical neuropathology, muscle biopsies, and autopsy pathology. (duke.edu)
  • Clinical trials have demonstrated the efficacy of etidronate disodium in heterotopic ossification following total hip replacement or due to spinal cord injury. (nih.gov)
  • He is currently working on understanding the extreme responders and extreme clinical phenotypes of brain and spinal cord tumors to identify factors that may modulate responses to therapy. (hopkinsmedicine.org)
  • Intramuscular diaphragm stimulation for ventilator-dependent chronic respiratory failure from high spinal cord injuries should only be used with special arrangements for clinical governance, consent, and audit or research. (bvsalud.org)
  • Neoplastic disease that involves the spine and results in spinal cord or cauda equina compression may have devastating neurologic and functional consequences. (medscape.com)
  • Neoplastic disease can cause neurologic symptoms by compression of the thecal sac, spinal cord, or cauda equina, as well as compression of the attendant vascular supply, which results in cord edema and ischemia. (medscape.com)
  • Cauda equina syndrome (CES) is a condition that occurs when the bundle of nerves below the end of the spinal cord known as the cauda equina is damaged. (wikipedia.org)
  • After the conus medullaris (near lumbar vertebral levels 1 (L1) and 2 (L2), occasionally lower), the spinal canal contains a bundle of nerve fibers (the cauda equina or "horse-tail") that branches off the lower end of the spinal cord and contains the nerve roots from L1-L5 and S1-S5. (wikipedia.org)
  • Metastatic disease can promote end-organ dysfunction and even failure through mass effect compression of various vital organs including the spinal cord. (elsevierpure.com)
  • In 1 patient who underwent surgery for spinal cord neoplasm, the procedure excluded arachnoiditis. (ajnr.org)
  • The neural tracts most vulnerable to mechanical pressure include the corticospinal and spinocerebellar tracts and the posterior spinal columns. (medscape.com)
  • Lhermitte's sign (an electric-shock sensation elicited by neck flexion that runs down the spine and sometimes into the limbs) suggests involvement of the posterior columns of the cervical spinal cord. (emcrit.org)
  • Morbidity and Mortality in the surgical treatment of 10,242 adults with spondylolistheis. (umaryland.edu)
  • T2-weighted MR presented an isointense, homogeneous, well-defined lesion localized in the right side of the vertebral body of C3 and C4 invading the ipsilateral VA, myelo-scan presented compression of the spinal cord. (surgicalneurologyint.com)
  • Myelopathy can be the result of primary intrinsic disorders of the spinal cord or from secondary conditions, which result in extrinsic compression of the spinal cord. (bvsalud.org)
  • Chordomas generally occur in 3 locations, which are, in descending order of frequency, the sacrum, intracranially at the clivus, and along the spinal axis. (spinalsurgerynews.com)
  • Nerves to the cervical cord are located closest to the middle of the cord, whereas nerves to the sacrum are located farthest towards the edges of the spinal cord. (emcrit.org)
  • A novel minimally invasive technique for spinal cord untethering. (backbonejournal.com)
  • 9] Sandhu FA, Santiago P, Fessler RG, Palmer S. Minimally invasive surgical treatment of lumbar synovial cysts. (backbonejournal.com)
  • Today, with the advancement in technology, many of the procedures may be performed through a small opening using an endoscope or microscope called as minimally invasive spinal surgery (MISS ). Lesser damage to muscles around the spine, faster recovery and lesser pain are the advantages of MISS. Other newer methods include artificial disc replacement procedures which completely preserve the mobility of the spine yet confer admirable stability as well. (sakraworldhospital.com)
  • Specialist medical or surgical review is indicated for severe or progressive back or leg pain that is unresponsive to other therapy, progressive neurological deficits, or other signs of specific and/or serious pathology. (safetyandquality.gov.au)
  • Surgical intervention in HCS is challenging due to severe osteoporosis, ligamentous laxity, POCSs, and extreme skeletal deformities. (thejns.org)
  • Overview of Spinal Cord Disorders Spinal cord disorders can cause permanent severe neurologic disability. (msdmanuals.com)
  • Past two decades have seen many advancements in treatment of spine deformities right from initial radiographic assessment, surgical planning to postoperative care. (backbonejournal.com)
  • Spinal manifestations of NF1 include bone changes such as acute kyphoscoliosis at the cervical-thoracic junction and vertebral body anomalies, soft-tissue abnormalities such as dural ectasia and lateral meningocele, and various spinal tumors. (ajnr.org)
  • however, they constitute 2-4% of all primary bone neoplasms. (spinalsurgerynews.com)
  • Most extradural tumors invade and destroy bone before compressing the spinal cord. (msdmanuals.com)
  • This comprehensive book is the result of the contribution of different internationally renowned expert teams in the management of bone tumors and particularly spinal neoplasms. (novapublishers.com)
  • Etidronate disodium tablets, USP are indicated for the treatment of symptomatic Paget's disease of bone and in the prevention and treatment of heterotopic ossification following total hip replacement or due to spinal cord injury. (nih.gov)
  • The following article describes various imaging modalities and their application in the evaluation of common spinal disorders described. (elpasochiropractorblog.com)
  • The tissue is examined grossly and microscopically for signs of neoplasms, vascular disease, inflammatory processes, neurodegenerative disorders, developmental abnormalities, and other pathological processes. (duke.edu)
  • Cushing, whose surgical and scientific interests had begun centering on disorders of the nervous system - and who became the first to declare neurosurgery a separate specialty - refocused the Hunterian's mission on neurosurgical research and techniques. (hopkinsmedicine.org)
  • Surgical Management of Global Sagittal Deformity in Ankylosing Spondylitis. (umaryland.edu)
  • Preoperative spinal alignment, surgical treatment, postoperative deformity, and risk factors for deformity were evaluated. (duke.edu)
  • Treatment may include corticosteroids, surgical excision, and radiation therapy. (msdmanuals.com)
  • The aim of this monocentric study is to report on the safety and efficacy of CFR-PEEK pedicle screw systems for spinal neoplasms in a large cohort of consecutive patients. (scite.ai)
  • Surgical removal of ribs , allowing the chest wall to move inward and collapse a diseased lung . (lookformedical.com)
  • Spinal tumors may develop within the spinal cord parenchyma, directly destroying tissue, or outside the cord parenchyma, often compressing the cord or nerve roots. (msdmanuals.com)
  • Leptomeningeal metastasis presents as multifocal neurological deficits referable to the spinal cord. (medscape.com)