• molecules
  • Binding of pathogens, allergens, and other molecules Increasing phagocytosis and chemotaxis of alveolar macrophages Induction of proliferation of immune cells Stimulation of proinflammatory cytokine production Modulation of the generation of reactive oxygen species Serving as a hormone in parturition Maintaining the structure of tubular myelin (an extracellular form of surfactant) The role of SFTPA2 in innate immunity has been extensively studied. (wikipedia.org)
  • receptors
  • They can also be seen as secreted forms of pattern recognition receptors (PRRs).7 These include collectins, components of complement pathways (e.g. (wikipedia.org)
  • There is a specific interaction between collectins and receptors on phagocytic cells which can lead to increased clearance of microorganisms. (wikipedia.org)
  • phagocytosis
  • Binding of collectins to microorganisms may trigger elimination of microorganisms by aggregation, complement activation, opsonization, activation of phagocytosis, or inhibition of microbial growth. (wikipedia.org)
  • Genetic
  • citation needed] Post-doctoral research on "Role of lung collectins in genetic predisposition to aspergillosis" as Senior Research Associate at Institute of Genomics and Integrative Biology (IGIB) (Council of Scientific and Industrial Research, CSIR), Delhi, India. (wikipedia.org)
  • function
  • Quantitative and/or qualitative alterations in surfactant composition and/or function are associated with respiratory diseases. (wikipedia.org)
  • Changes in the amount or composition of surfactant can alter its function and are associated with respiratory diseases. (wikipedia.org)