• arrays
  • With the emergence of surface plasmon resonance (SPR) arrays, investigators now have high-throughput capabilities to accelerate their biotherapeutic mAb-screening campaigns, while using minimal volumes of samples that are often available only at low concentration and in limiting quantities. (genengnews.com)
  • interaction
  • The different approaches towards SPL can be classified by their goal to either add or remove material, by the general nature of the process either chemical or physical, or according to the driving mechanisms of the probe-surface interaction used in the patterning process: mechanical, thermal, diffusive and electrical. (wikipedia.org)
  • The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. (wikipedia.org)
  • occurs
  • When the energy as well as the momentum of both, the incident light and SPW, match, a resonance occurs which results in a sharp dip in the reflected light intensity. (hindawi.com)
  • parameter
  • A film that is either too thick or too thin will adsorb particles onto the surface, therefore film thickness becomes an important parameter in the synthesis of ultra-low fouling surfaces. (wikipedia.org)
  • Phase
  • A net charge difference is created in the surface of the metal film, creating a collective dipolar oscillation of electrons with the same phase. (wikipedia.org)
  • Thermochemical scanning probe lithography (tc-SPL) or thermochemical nanolithography (TCNL) employs the scanning probe tips to induce thermally activated chemical reactions to change the chemical functionality or the phase of surfaces. (wikipedia.org)
  • reactions
  • Bias-induced scanning probe lithography (b-SPL) uses the high electrical fields created at the apex of a probe tip when voltages are applied between tip and sample to facilitate and confining a variety of chemical reactions to decompose gases or liquids in order to locally deposit and grow materials on surfaces. (wikipedia.org)
  • hence
  • Moreover, simple isolated surface defects such as a groove, a slit or a corrugation on an otherwise planar surface provides a mechanism by which free-space radiation and SPs can exchange energy and hence couple. (wikipedia.org)
  • polymer
  • One solution would be to layer the surface with a low surface energy polymer such as polydimethylsiloxane (PDMS). (wikipedia.org)
  • the first being physisorption of an amphiphilic diblock co-polymer where the hydrophobic block adsorbs to the surface, leaving the hydrophilic block available for anti-fouling purposes. (wikipedia.org)
  • The physisorption results in mushroom regimes leaving much of the surface area of the hydrophilic polymer coiled up on itself while the grafting from approach results in highly ordered, tailorable, brush polymers. (wikipedia.org)
  • properties
  • Unwanted adsorbates caused by fouling change the properties of a surface, which is often counter-productive to the function of that surface. (wikipedia.org)
  • Although chemical fouling inhibitors, metallic coatings, and cleaning processes can be used to reduce fouling, non-toxic surfaces with anti-fouling properties are ideal for fouling prevention. (wikipedia.org)
  • Oxidizing the PDMS surface does generate hydrophilic anti-fouling properties, but the low glass transition temperature allows for surface reconstruction via internal rearrangement: destroying hydrophilicity. (wikipedia.org)
  • ligands
  • After enzymatic C3b coupling or standard amine C3b coupling, we analyzed and compared the binding of four C3b ligands to the surface: factor B, factor H, C5 and the soluble complement receptor 1 (sCR1, CD35). (diva-portal.org)
  • present
  • The present invention relates to a fluorescence microscope using Surface plasmon resonance (SPR), for maximizing a fluorescence signal of a bio-sample to which a flu- orophore is labeled, using SPR to enable monitoring of the bio-sample. (google.com)
  • The more active conformation is thought to be induced when Factor H binds to glycosaminoglycans (GAGs) and or sialic acids that are generally present on host cells but not, normally, on pathogen surfaces ensuring that self surfaces are protected whilst complement proceeds unabated on foreign surfaces. (wikipedia.org)
  • allows
  • Once C3 is activated to C3b, it exposes a reactive thioester that allows the peptide to covalently attach to any surface that can provide a nucleophile such as a primary amine or a hydroxyl group. (wikipedia.org)
  • This allows for a cheap, readily available substrate (PDMS) to be easily converted into an anti-fouling surface. (wikipedia.org)
  • eventual
  • Due to the eventual degradation of the polyethylene glycol (PEG) anti-fouling surfaces, new techniques employ zwitterionic polymers containing carboxybetaine or sulfobetaine due to their comparable hydration by water. (wikipedia.org)
  • development
  • The second way is via surface initiated polymerization techniques which has been greatly influence by the development of controlled radical polymerization techniques such as Atom Transfer Radical Polymerization (ATRP). (wikipedia.org)