• Mutations that occur within the immunodominant epitopes of hepatitis B surface antigen (HBsAg) allow mutant virus to propagate in the presence of a neutralizing immune response, while wild-type virus is reduced to undetectable levels. (cdc.gov)
  • An understanding of immunoassay reactivity with HBsAg mutants is key to establishing an appropriate testing algorithm for hepatitis B virus detection programs. (cdc.gov)
  • This article addresses recent information concerning the emergence of hepatitis B surface antigen (HBsAg) mutants, their impact on viral antigen presentation, latest prevalence data, and discussion of the issues associated with detection of mutants in healthcare settings. (cdc.gov)
  • We determined the serum level of antibody to hepatitis B surface antigen (anti-HBsAg) in 273 randomly selected 7-9-year-old schoolchildren from Zanjan City, Islamic Republic of Iran, who had been fully vaccinated against hepatitis B starting at birth. (who.int)
  • The surface antigen, HBsAg is a good marker in the estimation of the number of hepatitis B virus (HBV) carriers among a population because its presence shows either an acute viral hepatitis B or a chronic carriage state of the HBV [ 1 - 3 ]. (omicsonline.org)
  • HBsAg adalah kepanjangan dari Hepatitis B surface Antigen, yang merupakan antigen permukaan virus hepatitis B. Pemeriksaan HBsAg dilakukan untuk memastikan diagnosis hepatitis B. Jika hasil pemeriksaan HBsAg positif, berarti Anda terinfeksi virus hepatitis B (VHB) dan berisiko menularkan penyakit ini ke orang lain melalui darah atau cairan tubuh Anda. (sinergimsas.net)
  • Virus hepatitis B memiliki antigen permukaan (disebut HBsAg) yang menyebabkan sistem kekebalan tubuh Anda membuat antibodi. (sinergimsas.net)
  • Apabila setelah pemeriksaan diketahui hasil HBsAg positif, artinya Anda terinfeksi virus hepatitis B dan berpotensi menyebarkan VHB ke orang lain. (sinergimsas.net)
  • Meski pemeriksaan HBsAg dapat membantu mendiagnosis hepatitis B, tes ini tidak dapat membedakan apakah infeksi yang dialami oleh penderita bersifat akut atau kronis. (sinergimsas.net)
  • Seseorang mungkin memerlukan pemeriksaan HBsAg jika dokter mencurigai adanya kemungkinan Anda mengalami infeksi hati yang disebabkan oleh virus hepatitis B. (sinergimsas.net)
  • Anda mungkin juga akan memerlukan pemeriksaan HBsAg jika Anda mengalami gejala khas hepatitis B seperti jaundice atau ikterus ( penyakit kuning ), air kencing berwarna pekat atau gelap, nyeri perut bagian bawah, serta nafsu makan yang menurun secara drastis selama beberapa waktu. (sinergimsas.net)
  • Selain digunakan untuk mendiagnosis penyakit hepatitis B, pemeriksaan HBsAg juga dilakukan untuk melihat seberapa baik pengobatan hepatitis B yang Anda jalani bekerja. (sinergimsas.net)
  • The main antigen of the shell is HBsAg - the surface antigen of the virus. (lab24.pl)
  • During 2017, the president of Uzbekistan have active infection, including those who had a positive test issued a decree calling for the elimination of HBV and HCV result for hepatitis B surface antigen (HBsAg) and those who infections to meet WHO's 2030 hepatitis elimination targets had a positive test result for HCV core antigen. (cdc.gov)
  • Artron One Step Hepatitis B Surface Antigen Test is an immunochromatographic assay for the qualitative detection of HBsAg in human serum or plasma at or above the concentration of 1 ng/ml. (artronlab.com)
  • Artron One Step HBsAg test is an antigen-capture immunochromatographic assay, that detects the presence of HBsAg in blood samples. (artronlab.com)
  • HBsAg is the serologic hallmark of Hepatitis B Virus (HBV) infection that appears after acute inflammation. (yashraj.com)
  • For more than two decades, our flagship products of CRP, Cancer Antigens and HBsAg-Ad, HBsAg-Ay, NGAL, rSLO and rProlactin have routinely passed quality audits of leading global diagnostic manufacturers. (yashraj.com)
  • We evaluated hepatitis B floor antigen (HBsAg) kinetics after NAs discontinuation and through retreatment resulting from off-treatment scientific relapse amongst non-cirrhotic HBeAg-positive CHB sufferers. (jointsjournal.eu)
  • Therefore, HBsAg quantification (qHBsAg), HB corerelated antigen (HBcrAg) and HBV RNA among others, have been suggested as additional markers that could predict more precisely, patients with active infection who are likely to have long term complications [12]. (jscimedcentral.com)
  • There is a renewed interest in the quantitative HBsAg (qHBsAg) assay as a marker of hepatitis B viral activities in the last ten years [13]. (jscimedcentral.com)
  • Hepatitis B surface antigen (HBsAg) is the first serologic marker appearing in the serum at 6 to 16 weeks following exposure to HBV. (bookmytest.co.in)
  • There is a dearth of consensus national prevalence data on Hepatitis B surface antigen (HBsAg) infection in Nigeria and in our institution, a tert iary hospital in southwest Nigeria, and no prevalen ce study is available. (interesjournals.org)
  • The LINEAR Hepatitis B Antigen ( HBsAg ) Cassette Test detects HBSAG concentration greater than 2 ng/ml ( including any subtypes ) in human serum by the development of a colored line in the test region of the test device. (frenovobio.com)
  • The LINEAR Hepatitis B Antigen ( HBsAg ) Cassette Test uses an antibody that is highly specific for Hepatitis B Antigen ( HBsAg ) in serum. (frenovobio.com)
  • The Hepatitis B surface antigen (HBsAg) test is done to confirm the presence or absence of the Hepatitis virus in the blood. (frenovobio.com)
  • HBsAg is also known as Australian Antigen. (frenovobio.com)
  • Background and objectives: Serum Hepatitis B surface Antigen (HBsAg) levels correlate with hepatitis B virus intrahepatic covalently closed circular DNA and may predict response to treatment. (eur.nl)
  • Study design: HBsAg levels were measured in 1427 serum samples from HBeAg-positive chronic hepatitis B patients who participated in a randomized trial of peginterferon alfa-2b +/- lamivudine. (eur.nl)
  • The hepatitis B surface antigen (HBsAg) test is used to detect the presence of hepatitis B surface antigens in your blood. (metropolisindia.com)
  • The HBsAg test is usually performed as part of a panel of tests, such as the hepatitis B panel, which also includes tests for other hepatitis viruses. (metropolisindia.com)
  • Your doctor may recommend the HBsAg test if you have symptoms of acute hepatitis B, such as fatigue, fever, abdominal pain, dark urine, or yellowing of your skin or eyes ( jaundice ). (metropolisindia.com)
  • If the HBsAg test is positive, it means that you have a chronic hepatitis B infection and require treatment. (metropolisindia.com)
  • The HBsAg test is used to screen for hepatitis B infection and to help diagnose acute or chronic hepatitis B. This test can also be used to monitor people who are at risk for hepatitis B infection, such as people with HIV or those who have been exposed to the virus. (metropolisindia.com)
  • The HBsAg test is used to diagnose hepatitis B, determine if you are a carrier of the virus, and monitor the effectiveness of treatment for hepatitis B. (metropolisindia.com)
  • The HBsAg test is usually done as part of a panel of tests for hepatitis B. Other tests in this panel may include the hepatitis B core antibody (HBcAb) and the hepatitis B surface antibody (HBsAb). (metropolisindia.com)
  • Here, we aimed to investigate the role of HBV DNA and hepatitis B surface antigen ( HBsAg ) monitoring to predict off- treatment sustained response. (bvsalud.org)
  • Monitoring of HBsAg level can guide the timing of stopping lamivudine in HBeAg -negative chronic hepatitis B . (bvsalud.org)
  • Hepatitis B surface antigen (HBsAg) was employed as a model protein biomarker to demonstrate the analytical performance of the sensor in this study. (cdc.gov)
  • Testing to identify pregnant women who are hepatitis B surface antigen (HBsAg)-positive and providing their infants with immunoprophylaxis effec- tively prevents HBV transmission during the perinatal period (4,5). (cdc.gov)
  • More than 90% of these infections can be prevented if HBsAg-positive mothers are identified so that their infants can receive hepatitis B vaccine and hepatitis B immune globulin (HBIG) soon after birth (4,5). (cdc.gov)
  • Monoclonal antibody 2F10 is an "internal-image" anti-idiotype (anti-id) antibody capable of mimicking the group-specific "a" determinant of human hepatitis B surface antigen (HBsAg). (uthscsa.edu)
  • We conclude that a 15-mer peptide derived from the anti-id sequence can duplicate the B- and T-cell stimulatory activity of the intact anti-id antibody and the antigen that is mimicked, HBsAg. (uthscsa.edu)
  • The objective of this study is to produce an IgY with activity against synthetic peptide analogs of known immunogenic epitopes of the Hepatitis B Surface Antigen (HBsAg) - a molecular marker of Hepatitis B infection. (edu.ph)
  • Chickens were immunized with synthetic peptide analogs of previously reported immunogenic epitopes of the S and the pre-S1 regions of the Hepatitis B surface antigen (HBsAg). (edu.ph)
  • Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. (scielo.br)
  • HBsAg was the first viral antigen chosen to be produced in transgenic plants, firstly in tobacco [3] and subsequently in lupin callus and lettuce adapted to colder climates [4]. (scielo.br)
  • Thus, striking improvements in recombinant antigen were achieved by alternative polyadenylation signals and fusion proteins containing targeting signals designed to enhance integration or retention of HBsAg in the endoplasmic reticulum (ER) of plant cells [6]. (scielo.br)
  • A screening law was identified if the state requires screening of pregnant woman for hepatitis B infection or hepatitis B surface antigen (HBsAg). (cdc.gov)
  • Horseradish peroxidase (HRP)-labeled antibody conjugate (mouse monoclonal anti-HBc) is then allowed to react with the remaining exposed HBcAg on the well surface. (cdc.gov)
  • The prevalence of infection for at least 15 years, that antibody hepatitis B carriers varies in different parts levels decrease the most among persons of the world, ranging from less than 1% to immunized at 4 years of age or younger, and 15% [ 2 ]. (who.int)
  • Murine monoclonal IgG1 antibody to Hepatitis B Surface Antigen (HBs). (arxsciences.com)
  • A Hepatitis B core antibody is a blood test that looks for antibodies to the core of the hepatitis B virus. (metropolisindia.com)
  • The hepatitis B surface antibody (HBsAb) test is used to detect the presence of antibodies against the hepatitis B virus (HBV). (metropolisindia.com)
  • ACIP also recommends that vaccinated HCP receive postvaccination serologic testing (antibody to hepatitis B surface antigen [anti-HBs]) 1-2 months after the final dose of vaccine is administered (CDC. (cdc.gov)
  • Result(s): The CVA6-specific antibody demonstrated appropriate antigen distribution and staining intensity in keratinocytes in all cases. (cdc.gov)
  • In 1991, the World at least 6-8 years before with 3 doses of Health Organization (WHO) recommended hepatitis B vaccine starting at birth to that hepatitis B vaccination be included provide information on the effect of the in national immunization programmes in immunization strategy for hepatitis B and countries with a hepatitis B surface antigen the need for booster doses. (who.int)
  • To demonstrate manufacturing equivalence of a 3-antigen (3A) HBV vaccine, evaluate noninferiority of seroprotection rate (SPR) of 3A-HBV vs single-antigen (1A) HBV after 2 and 3 vaccine doses, and compare safety and reactogenicity between 3A-HBV and 1A-HBV vaccines. (nih.gov)
  • If the test results show a negative reaction and noantibodies, you may consider taking hepatitis B vaccine to prevent viralinfection. (kinetics-eshop.hk)
  • Although a high proportion of healthy vaccine recipients in clinical trials respond to hepatitis B (HepB) vaccination, the proportion of responders can be lower among the general population, particularly among persons with chronic medical conditions ( 6 , 7 ). (cdc.gov)
  • Breakthrough cases of Hepatitis B are primarily attributed to mutations in the Hepatitis B virus (HBV) that make HBV surface proteins unrecognizable to antibodies produced from the HBV vaccine. (wikipedia.org)
  • This prevention strategy includes making hepatitis B vaccine a part of routine vaccination schedules for all infants. (cdc.gov)
  • Immunization with hepatitis B vaccine is the most effective means of preventing HBV infection and its consequences. (cdc.gov)
  • Integrating hepatitis B vaccine into childhood vaccination schedules in populations with high rates of childhood infection (e.g. (cdc.gov)
  • The recommendations for implementing this strategy include making hepatitis B vaccine a part of routine vaccination schedules for infants. (cdc.gov)
  • The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. (scielo.br)
  • Their respective clinical diagnoses are asymptomatic carrier, hepatitis B e antigen- (HBeAg-) positive hepatitis, inactive carrier, and HBeAg-negative hepatitis. (hindawi.com)
  • The timing of antiviral therapy cessation in hepatitis B e antigen ( HBeAg )-negative patients is controversial. (bvsalud.org)
  • A total of 53 HBeAg -negative chronic hepatitis B patients who received lamivudine for 34 ±23 (range 12-76) months and had lamivudine stopped for 47 ±35 months were studied. (bvsalud.org)
  • The risk of perinatal HBV infection among infants born to HBV-infected mothers ranges from 10% to 85%, depending on each mother's hepatitis B e antigen (HBeAg) status (3,7,8). (cdc.gov)
  • ABSTRACTHBsAg and HBeAg have gained traction as biomarkers of control and clearance during monitoring of chronic hepatitis B virus infection (CHB). (ox.ac.uk)
  • ABSTRACT The duration of protection after hepatitis B vaccination in children is unknown. (who.int)
  • It has been reported that when hepatitis services is good throughout the territory, B vaccination is initiated at birth, there and vaccinations are delivered through local is an increased likelihood that the child health districts which are able to reach the will complete the series [ 8,9 ] hence an whole population. (who.int)
  • When deciding on the need for vaccination against viral hepatitis B. (lab24.pl)
  • The hepatitis B virus (HBV) vaccination schedule in Libya follows international recommendations (1st dose at birth, 2nd after 1 month and 3rd after 6 months). (hud.ac.uk)
  • Madour, A, Alkout, A & Vanin, S 2013, ' Première évaluation de la concentration sérique de l'antigène de surface du virus de l'hépatite b après la vaccination en Libye ', Eastern Mediterranean Health Journal , vol. 19, no. 12, pp. 990-994. (hud.ac.uk)
  • Explicit guidance is provided for persons working, training, or volunteering in health-care settings who have documented hepatitis B (HepB) vaccination years before hire or matriculation (e.g., when HepB vaccination was received as part of routine infant [recommended since 1991] or catch-up adolescent [recommended since 1995] vaccination). (cdc.gov)
  • This report emphasizes the importance of administering HepB vaccination for all HCP, provides explicit guidance for evaluating hepatitis B protection among previously vaccinated HCP (particularly those who were vaccinated in infancy or adolescence), and clarifies recommendations for postexposure management of HCP exposed to blood or body fluids. (cdc.gov)
  • Introduction: Antibodies to Hepatitis B surface Antigen (Anti-HBs) levels are measured as markers for immune response to vaccination and in decision making for post-exposure prophylaxis against Hepatitis-B. Several immunoassay formats are used to measure Anti-HBs, thus carrying the possibility of variation in measured levels between different assays. (manipal.edu)
  • There is a need for improved immunogenicity of hepatitis B virus (HBV) vaccines among young adults with risk of infection. (nih.gov)
  • Despite the availability of hepatitis B vaccines and Hepatitis B virus (HBV) and hepatitis C virus (HCV) infec- treatment for hepatitis B and C, few low- and middle-income tion prevalences are high in Uzbekistan, which lacks funding countries have sustainable and scalable elimination programs. (cdc.gov)
  • For pregnancy, those include hepatitis A and meningococcal vaccines, which I'll not go into today. (cdc.gov)
  • Vaccines recommended during pregnancy that are in yellow across these two slides include hepatitis B, COVID-19, influenza, and Tdap. (cdc.gov)
  • The aim of this study was to describe the pattern of Hepatitis B surface antigen and DNA quantification among patients with e negative chronic hepatitis B virus infection attending two hospitals in south west Nigeria and determine if any, correlation between the two. (jscimedcentral.com)
  • This study aimed to describe the pattern of quantitative hepatitis B surface antigen and DNA quantification among patients with e negative chronic hepatitis B. (jscimedcentral.com)
  • Major international and local guidelines suggested the use of serum HBV DNA quantification and serum alanine transferase (ALT) as markers to select patients with active chronic hepatitis B infection [7-10]. (jscimedcentral.com)
  • European Association for the Study of the Liver (EASL) and Asian Pacific Association for the study of the liver (APASL) guidelines recommended HBVDNA quantification greater than or equal to 2000IU/ml and raised serum alanine transaminase as criteria for active chronic hepatitis B infection which should be treated. (jscimedcentral.com)
  • Established in 1999 as a research focused Biotech Company with ISO certifications ISO 13485:2016 and ISO 9001:2015, YBL manufactures a wide range of high pure biomarkers in the form of native and recombinant antigens that are used by the diagnostic industry as controls, calibrators and immunogens. (yashraj.com)
  • abstract = "To assess the hepatitis risk to patients exposed to HB(s) AG positive health care workers, 228 contacts were followed prospectively, for 6 to 9 mth. (johnshopkins.edu)
  • Serum specimens are processed, stored, and shipped to the Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention. (cdc.gov)
  • Title : Prevention of perinatal transmission of hepatitis B virus : prenatal screening of all pregnant women for hepatitis B surface antigen Corporate Authors(s) : National Center for Infectious Diseases (U.S.). Division of Viral Hepatitis. (cdc.gov)
  • There is however paucity of data on the pattern of quantitative hepatitis B surface antigenaemia and its correlation with the viral loadin sub-Sahara Africa. (jscimedcentral.com)
  • Health workers included 2 physicians with chronic hepatitis, a chronic asymptomatic carrier nurse, a food handler with acute HB(s) Ag positive hepatitis and a physician who was HB(s) Ag positive for 25 days before the onset of acute hepatitis. (johnshopkins.edu)
  • It has two determinants Ad and Ay and helps in detection of Hepatitis infection or any other liver ailments. (yashraj.com)
  • Prior informed consent, antigen detection of hepatitis B surface was performed by ELISA in women between 15 and 44 years with a mean age of 26.6 (±6.8) years. (una.py)
  • Surface antigen can be detectable as early as 2 weeks, waiting 4 to 6 weeks is encouraged, but detection can sometimes take longer. (aboutmyhealth.us)
  • Hepatitis viruses constitute a major public health problem because of the morbidity and mortality associated with the acute and chronic consequences of these infections. (cdc.gov)
  • NHANES testing for markers of infection with hepatitis viruses will be used to determine secular trends in infection rates across most age and racial/ethnic groups, and will provide a national picture of the epidemiologic determinants of these infections. (cdc.gov)
  • This study was undertaken to determine the seroprevalence of HBsAgs and anti-HCV antibodies and what socio-demographic factors are associated with sero-positivity of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) infections among pregnant women attending maternity ward of Felege Hiwot Referral Hospital, northwest, Ethiopia. (biomedcentral.com)
  • Seroprevalnce of hepatitis B and C virus infections were found to be 4.4 and 0.26 %, respectively. (biomedcentral.com)
  • Hepatitis is the inflammation of liver, most commonly caused by viral infections. (biomedcentral.com)
  • Of these, hepatitis B virus (HBV) and hepatitis C virus (HCV) are of greater importance and among the most frequent viral infections in humans [ 1 , 2 ]. (biomedcentral.com)
  • Although the rate of acute hepatitis B virus (HBV) infections have declined approximately 89% during 1990-2011, from 8.5 to 0.9 cases per 100,000 population in the United States, the risk for occupationally acquired HBV among HCP persists, largely from exposures to patients with chronic HBV infection. (cdc.gov)
  • The reported incidence of acute hepatitis B increased by 37% from 1979 to 1989, and an estimated 200,000-300,000 new infections occurred annually during the period 1980- 1991. (cdc.gov)
  • Hepatitis B Core antigen test is used to detect hepatitis B virus (HBV) infection in an individual. (thyrocare.com)
  • There are several tests for the diagnosis of current or transferred viral hepatitis B. The determination of viral antigens and antibodies is performed to detect carriage, acute or chronic infection in the presence or absence of symptoms, in the monitoring of chronic infection. (lab24.pl)
  • Detect hepatitis B surface antigen, earliest indicator of acute hepatitis B infection, and also indicative of a chronic infection. (aboutmyhealth.us)
  • Hepatitis B surface antigen assays : operational characteristics (phase 1) : report 2. (who.int)
  • To decide on the expediency of prescribing immunoglobulin to patients with viral hepatitis and a high risk of infection. (lab24.pl)
  • Isolated elevations in serum glutamic pyruvic transaminase occurred equally in both groups and did not correlate with serologic evidence for hepatitis B infection. (johnshopkins.edu)
  • To determine transferred viral hepatitis B and the development of post-infectious immunity. (lab24.pl)
  • It can also help to determine if someone who has already been infected with hepatitis B has developed immunity to the virus. (metropolisindia.com)
  • Thus genes and haplotypes encoding these receptors may be important in determining both outcome of initial hepatitis infection and subsequent chronic liver disease and tumour formation. (edgehill.ac.uk)
  • This document provides the rationale for a comprehensive strategy to eliminate transmission of HBV and ultimately reduce the incidence of hepatitis B and hepatitis B-associated chronic liver disease in the United States. (cdc.gov)
  • However, not all patients with chronic hepatitis B will develop these complications. (jscimedcentral.com)
  • Patients with chronic hepatitis B infection can be immune tolerant or have an inactive chronic infection without any evidence of active disease, and they are also asymptomatic. (medscape.com)
  • Patients with chronic active hepatitis, especially during the replicative state, may have symptoms similar to those of acute hepatitis. (medscape.com)
  • In the United States, 2,890 cases of acute hepatitis B were reported to CDC in 2011, and an estimated 18,800 new cases of hepatitis B occurred after accounting for underreporting of cases and asymptomatic infection. (cdc.gov)
  • However, in 2006 were confirmed 14,761 cases of hepatitis B in the country. (scielo.br)
  • This document provides the rationale for a comprehensive strategy to eliminate transmission of hepatitis B virus in the United States. (cdc.gov)
  • Although there has been some conflict regarding the transmission of hepatitis B, the most likely modes of transmission include exposure to infected blood, semen, and/or vaginal secretions. (aboutmyhealth.us)
  • Hepatitis B viral mutants can emerge in patients as a result of selection pressure from either immune response or treatment options. (cdc.gov)
  • The foremost histocompatibility complicated (MHC) class II characterised by monocytes CD14+ expression of human leukocyte antigen receptors (HLA-DR), is important for the synapse between innate and adaptive immune response in infectious illness. (jointsjournal.eu)
  • Autoimmune Hepatitis is a disorder in which the body's own immune system mistakenly targets cells in the liver. (requestatest.com)
  • The pathogenesis and clinical manifestations of hepatitis B are due to the interaction of the virus and the host immune system, which lead to liver injury and, potentially, cirrhosis and hepatocellular carcinoma. (medscape.com)
  • Recommendations have also been developed for the prevention and control of hepatitis C virus (HCV) infection. (cdc.gov)
  • The safety and efficacy of 3A-HBV shows its usefulness for the prevention of hepatitis B in young healthy adults. (nih.gov)
  • Centers for Disease Control and Prevention (CDC) mengatakan bahwa penyakit hepatitis B kronis tidak dapat disembuhkan. (sinergimsas.net)
  • Recommendations concerning the prevention of other types of viral hepatitis are found in MMWR 1990;39(No. RR-2): 1-8, 22-26. (cdc.gov)
  • This involves the reaction of anti-HBc in the sample with hepatitis B core antigen (HBcAg) coated wells. (cdc.gov)