HomozygoteGenes, Tumor SuppressorGenes, SuppressorTumor Suppressor ProteinsSuppressor of Cytokine Signaling ProteinsTumor Suppressor Protein p53HeterozygoteSuppression, GeneticGenotypeAllelesMutationPolymorphism, GeneticSuppressor Factors, ImmunologicPhenotypeGene FrequencyMolecular Sequence DataGenetic Predisposition to DiseaseBase SequencePolymorphism, Single NucleotideTumor Suppressor Protein p14ARFHemochromatosisT-Lymphocytes, RegulatoryVon Hippel-Lindau Tumor Suppressor ProteinGenes, LethalCell Line, TumorPromoter Regions, GeneticChromosome MappingGene Expression Regulation, NeoplasticPolymerase Chain ReactionAmino Acid SequenceGenes, p53Transcription FactorsGene DeletionDNA-Binding ProteinsSignal TransductionNuclear ProteinsMice, Mutant StrainsRepressor ProteinsHaplotypesCase-Control StudiesGenetic VariationHeterozygote DetectionCrosses, GeneticMembrane ProteinsPoint MutationRNA, MessengerPTEN PhosphohydrolaseGene SilencingDNA MethylationApoptosisGenes, RecessiveLoss of HeterozygosityMice, Inbred C57BLCarrier ProteinsRetinoblastoma ProteinCyclin-Dependent Kinase Inhibitor p16DNA Mutational AnalysisDNA PrimersNeoplasmsProteinsExonsCell Transformation, NeoplasticMice, KnockoutGenes, DominantProtein BindingTranscription, GeneticCells, CulturedCell ProliferationCell LineTumor Cells, CulturedTransfectionReverse Transcriptase Polymerase Chain ReactionApolipoprotein E2Cell Cycle ProteinsPolymorphism, Restriction Fragment LengthProto-Oncogene Proteins c-mdm2PedigreeDown-RegulationGene Expression RegulationDNAMutation, MissenseMyeloid CellsCell CycleT-LymphocytesRNA InterferenceGenetic MarkersCatechol O-MethyltransferaseCell DivisionAlbinismSpleenHyperlipoproteinemia Type IIDrosophila ProteinsProto-Oncogene ProteinsMice, TransgenicModels, GeneticImmunosuppressionMethylenetetrahydrofolate Reductase (NADPH2)CodonDrosophila melanogasterAmino Acid Substitution