• 4. Nakamura S, Shibuya M, Nakashima H, Hisamura R, Masuda N, Imagawa T, Uehara M, Tsubota K. Involvement of oxidative stress on corneal epithelial alterations in a blink-suppressed dry eye. (koreamed.org)
  • These dietary supplements may be used to prevent or suppress oxidative stress. (biomedcentral.com)
  • Manuka honey serves as an excellent source of antioxidants, which help eliminate free radicals, prevent cellular damage, protect against chronic diseases, combat premature aging of cells, suppress lipid peroxidation, and reduce oxidative stress. (aboutmanukahoney.com)
  • Here we report that exposure to partially purified SWCNTs (HiPco technique, Carbon Nanotech nologies, Inc., Houston, TX, USA) resulted in the augmentation of oxidative stress as evidenced by ESR detection of a-(4-pyridyl-1-oxide)-N-tert-butylnitrone spin-trapped carbon-centered lipid-derived radicals recorded shortly after the treatment. (cdc.gov)
  • Also oxidative stress suppresses the immune system's ability to protect and restore affected cells 10,12 . (bvsalud.org)
  • The chemical products of this oxidation are known as lipid peroxides or lipid oxidation products (LOPs). (wikipedia.org)
  • Bilirubin may act as an antioxidant that suppresses lipid oxidation. (ajol.info)
  • It contains Ellagic Acid found naturally in many fruits and known to suppress lipid per-oxidation, helping to inhibit the development of age spots. (skin-etc.com)
  • Lipid oxidation is a major cause of deterioration of shelf life of meat products which may produce changes in meat quality parameters such as colour, flavour, odour, texture and even nutritional value (Masniyom, 2011). (ijlr.org)
  • 2004). Hence, different strategies have been attempted to counteract the lipid oxidation of meat products such as using approved synthetic phenolic antioxidants (Shahidi and Zhong, 2010). (ijlr.org)
  • The active anti-oxidant compounds of onion extracts promote health by preventing lipid oxidation and providing antibacterial, anti-carcinogenic and antiviral ability (Procházková et al . (ijlr.org)
  • The extent of lipid oxidation was evaluated by 2-thiobarbituric acid-reactive substances (TBARS) method described by Raharjo et al . (ijlr.org)
  • It is the process in which free radicals "steal" electrons from the lipids in cell membranes, resulting in cell damage. (wikipedia.org)
  • The end products of lipid peroxidation are reactive aldehydes, such as malondialdehyde (MDA) and 4-hydroxynonenal (HNE), the second one being known also as "second messenger of free radicals" and major bioactive marker of lipid peroxidation, due to its numerous biological activities resembling activities of reactive oxygen h species. (wikipedia.org)
  • By using pro-inflammatory transcription factor NF-kappaB, COX-1 and -2 enzymes (responsible for producing substances that fight inflammation), human tumor cell proliferation and "lipid peroxidation" (the process in which free radicals "steal" electrons from lipids in our cell membranes, causing cell damage and increased production of free radicals), the researchers were able to determine the health-boosting properties of pepper. (doctorshealthpress.com)
  • Overall, we provide direct evidence that lipid-derived free radicals are a critical contributor to tissue damage induced by SWCNTs not only in the lungs, but also in distant organs. (cdc.gov)
  • An alternative, pharmaceutical method employs the isotope effect on lipid peroxidation of deuterated polyunsaturated fatty acids (PUFAs) at the methylene bridges (bis-allylic sites) between double bonds, which leads to the inhibition of the chain reaction. (wikipedia.org)
  • Other mechanisms may include inhibition of free-radical-mediated lipid peroxidation and amelioration of glutamate release. (anesthesiageneral.com)
  • This beneficial effect of propofol may be caused, in part, by inhibition of lipid peroxidation in the diaphragm caused by the powerful oxidant. (asahq.org)
  • In recent years, development of immunochemical detection of HNE-histidine adducts opened more advanced methodological possibilities for qualitative and quantitative detection of lipid peroxidation in various human and animal tissues[full citation needed] as well as in body fluids, including human serum and plasma samples. (wikipedia.org)
  • Increased serum MDA concentration, as a biomarker of lipid peroxidation, low serum bilirubin and antioxidant capacity were observed in patients with angiographically defined CAD. (ajol.info)
  • Following hepatic I/R, the levels of hepatic lipid peroxidation and serum alanine aminotransferase increased, while the ratio of hepatic glutathione (GSH):oxidized GSH was reduced, which was effectively attenuated by pretreatment with GP. (spandidos-publications.com)
  • Omega-3 fatty acids had no significant effect on serum lipid levels, ApoA-I, glucose, insulin and HbA1c. (who.int)
  • This study aimed to determine whether aerobic training could reduce lipid peroxidation and inflammation at rest and after maximal exhaustive exercise in overweight/obese adolescent girls. (humankinetics.com)
  • Training also prevented exercise-induced lipid peroxidation and/or inflammation in overweight/obese girls (F 2 -Isop, ROOH, ox-LDL, MPO). (humankinetics.com)
  • The researchers found that all compounds derived from black pepper suppressed the inflammation-producing transcription factor NF-kappaB. (doctorshealthpress.com)
  • This was accompanied by a significant depletion of antioxidants and elevated biomarkers of inflammation presented by recruitment of inflammatory cells and an increase in proinflammatory cytokines in the lungs, as well as development of multifocal granulomatous pneumonia, interstitial fibrosis, and suppressed pulmonary function. (cdc.gov)
  • Plus it protects neurons from damage, re-myelinates nerves, increases BDNF (brain derived neurotropic factor) and GDNF (glial derived neurotropic factor) which are low in PD, is converted into allopregnanolone and 5alpha-dihydroprogesterone which are low in PD, is involved in the dopamine pathway, prevents lipid peroxidation, stimulates the GABA receptors and more. (progesteronetherapy.com)
  • The toxicity of lipid hydroperoxides to animals is best illustrated by the lethal phenotype of glutathione peroxidase 4 (GPX4) knockout mice. (wikipedia.org)
  • These animals do not survive past embryonic day 8, indicating that the removal of lipid hydroperoxides is essential for mammalian life. (wikipedia.org)
  • Its unique signature that distinguishes it from other forms of cell death is the formation and accumulation of lipid hydroperoxides, particularly oxidized forms of polyunsaturated phosphatidylethanolamines (PEs), which drives cell death. (cdc.gov)
  • The results showed that ZnO NPs treatment stablized concentration-dependent toxicity, increased lipid peroxidation (LPO), reduced activity of antioxidants, augmented ROS production, and reduced MMP. (mendeley.com)
  • Kato S, Saitoh Y , Miwa N. Hydrogen-bubbled platinum-colloid suppresses human esophagus- or tongue-carcinoma cells with intracellular platinum-uptake and the diminished normal-cell mortality. (pu-hiroshima.ac.jp)
  • This radical is also an unstable species that reacts with another free fatty acid, producing a different fatty acid radical and a lipid peroxide, or a cyclic peroxide if it had reacted with itself. (wikipedia.org)
  • Sperm cell membranes are high in polyunsaturated fatty acids and are sensitive to oxygen free radical induced damage mediated by lipid peroxidation. (scialert.net)
  • Some previous data do not support the liter- process in the determination of morbidity ature suggesting adverse effects of omega-3 and mortality from coronary heart disease fatty acids on lipid peroxidation [ 2,21,35 ]. (who.int)
  • When compared to fish oil, krill oil research has been found to: enhance glucose metabolism in your liver, promote lipid metabolism, help to regulate the mitochondrial respiratory chain, and decrease cholesterol synthesis, whereas fish oil does not. (transparentlabs.com)
  • Moreover, pulmonary exposure to SWCNTs also caused the formation of carbon-centered lipid-derived radicals in the heart and liver at later time points (day 7 postexposure). (cdc.gov)
  • Additionally, SWCNTs induced a significant accumulation of oxidatively modified proteins, increase in lipid peroxidation products, depletion of antioxidants, and inflammatory response in both the heart and the liver. (cdc.gov)
  • In addition, the present study indicated that treatment with GP suppressed the I/R-induced increase in the pro-apoptotic protein levels of Bax and cytochrome c and the activity of caspase-3/8, as well as the I/R-induced decrease in the levels of anti-apoptotic protein Bcl‑2. (spandidos-publications.com)
  • Giving you plenty of protein to maintain & build lean mass, but not too much so that it would suppress hormone production. (beardresource.com)
  • Moreover, the beneficial effects of dR ameliorated the α-synuclein accumulation, DA neuron loss and elevated brain lipid peroxidation caused by dCHCHD2 loss. (nature.com)
  • She has a particular interest in examining the role of intramyocellular lipids (fat droplets stored in muscle cells) on insulin sensitivity and their presence in obese and athletic populations. (brocku.ca)
  • For years, moderate-intensity continuous training (MICT) has been the most popular exercise modality for improving body composition, cardiorespiratory fitness, insulin resistance, and lipid profile [ 2 , 5 ]. (hindawi.com)
  • FRC markedly suppressed the TBARS production in a concentration-dependent manner, leading to 50% (IC50) and 100% (IC100) inhibitory concentrations of 20 and 95 microg/mL, respectively, which was similar to the effect of butylated hydroxyanisole. (koreamed.org)
  • Light-dependent activation of mitochondrion-targeted dR (mito-dR) but not a mito-dR inactive mutant successfully transformed mitochondria from an OXPHOS-dependent powerhouse to a photoenergetic powerhouse, which accordingly reinforced the mitochondrial functions of the nerve terminals in terms of ATP production and Ca 2+ -buffering activity, suppressing ROS generation 10 , 11 . (nature.com)
  • On the other hand, it's unclear whether dietary lipid peroxides are bioavailable and play a role in disease, as a healthy human body has protective mechanisms in place against such hazards. (wikipedia.org)
  • Such D-PUFAs, for example, 11,11-D2-ethyl linoleate, suppress lipid peroxidation even at relatively low levels of incorporation into membranes. (wikipedia.org)
  • It also suppresses any excess oestrogen, which is an excitatory, inflammatory hormone, have they checked his levels? (progesteronetherapy.com)
  • 1) Saitoh Y* , Yonekura N, Matsuoka D, Matsumoto A. Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells. (pu-hiroshima.ac.jp)
  • 0.0001)) after adjustment for lipid status parameters and traditional risk factors in this study population. (ajol.info)
  • Lipid-based preparations of amphotericin B decrease but do not eliminate the nephrotoxicity compared with traditional amphotericin B. (medscape.com)
  • Overexpression of Bcl-2 functioned to suppress lipid peroxidation completely. (umn.edu)