Superior retinal and choroidal disease choroid diseases. Medical search. Frequent questions

Aim This study used swept-source optical coherence tomography (SS-OCT) to investigate subfoveal choroidal thickness (SFCT) in patients with thyroid-associated ophthalmopathy (TAO) who displayed different levels of disease activity and severity. (bmj.com)
The accuracy of activity prediction using subfoveal choroidal thickness is high. (bmj.com)
Thick-choroid CSC was defined as mean subfoveal choroidal thickness more than 300.0 μ m. (plos.org)
Mean subfoveal choroidal thickness was 396.71 ± 90.5 µm. (bvsalud.org)
Swept-source optical coherence tomography (SS-OCT) of 9 mm×9 mm scanning mode was used to measure the subfoveal choroidal thickness (SFCT) automatically in nine macular regions according to the Early Treatment Diabetic Retinopathy Study classification system using TOPCON Advanced Boundary Segmentation (TABS) software. (cjeo-journal.org)

Persistent serous retinal detachment in a patient with chronic CSC can lead to permanent visual impairment due to RPE decompensation and disruption of the photoreceptor ellipsoid zone [ 1 , 2 , 12 , 13 ]. (plos.org)
Optical coherence tomography (OCT) showed serous retinal detachment (SRD) and choroidal thickening in both eyes (OU). (bvsalud.org)
One study used OCT to examine 84 eyes with ME secondary to uveitis, which provided the added benefit of re-vealing or confirming the presence of epiretinal membranes and serous retinal detachment in 41 and 20 percent of their cases, respectively. (reviewofophthalmology.com)

While choroidal changes are associated with retinal diseases, such as age-related macular degeneration 3 and diabetic retinopathy, 4 , 5 the limited ability to characterize choroidal flow leaves its role in pathogenesis and progression unclear. (arvojournals.org)
According to the subdivision of the diabetic retinopathy treatment group, the choroid within the 6 mm of the macular fovea was divided into three concentric circles with the macular fovea as the center, namely, the central area with the diameter of 1 mm, the inner ring of 1-3 mm and the outer ring of 3-6 mm. (wanfangdata.com.cn)
There were 14 eyes with diabetic retinopathy, 11 eyes with age-related macular degeneration, 3 eyes with a branch retinal vein occlusion, and 3 eyes with an epiretinal membrane/macular hole. (biomedcentral.com)
Genentech is researching and developing new treatments for people living with a range of eye diseases that cause significant visual impairment and blindness, including wet age-related macular degeneration (AMD), diabetic macular edema (DME), diabetic retinopathy (DR), geographic atrophy (GA), and other retinal diseases. (ois.net)
These extracted markers or characterized fundus digital image features provide insights and relates quantitative retinal vascular topography abnormalities to various pathologies such as diabetic retinopathy, macular degeneration, hypertensive retinopathy, transient ischemic attack, neovascular glaucoma, and cardiovascular diseases. (hindawi.com)
All these features are useful for early detection of hypertensive and diabetic retinopathy, macular degeneration, acute stroke, neovascular glaucoma, and some other cardiovascular diseases [ 1 , 3 , 5 - 9 ]. (hindawi.com)
5 The study found a moderate correlation be-tween retinal thickness and decreasing visual ac-uity, although the degree of correlation has varied across studies with other investigators reported weak, 6 mo-de-rate, 7 and strong 8,9,10 cor-relations using varying statistical methods in di-verse pa-tient pop-ulations, including pa-tients with diabetic retinopathy, uveitis and CME. (reviewofophthalmology.com)

Among the baseline characteristics, serous pigment epithelial detachment (B = - 2.580, P = 0.032) and thick-choroid (B = 1.980, P = 0.019) were significantly associated with recurrence. (plos.org)
Thinner choroid and serous pigment epithelial detachment appear protective for recurrences. (plos.org)
Central serous chorioretinopathy (CSC) is characterized by serous neurosensory retinal detachment at the posterior pole due to leakage from the retinal pigment epithelium (RPE) [ 1 - 5 ]. (plos.org)
Patients with small visual field defects (eg, caused by a small retinal detachment) may describe their symptoms as blurred vision. (merckmanuals.com)

Abstract： Objective:To observe the characteristics of choroidal thickness in patients with macular edema secondary to superior temporal branch retinal vein occlusion (BRVO-ME).Methods:A retrospective control study. (wanfangdata.com.cn)
Intravitreal levels of vascular endothelial growth factor and interleukin-6 are correlated with macular edema in branch retinal vein occlusion [J].2006,244(3). (wanfangdata.com.cn)
Baseline choroidal thickness as a short-term predictor of visual acuity improvement following antivascular endothelial growth factor therapy in branch retinal vein occlusion [J].2019,103(1). (wanfangdata.com.cn)
Therapies for Macular Edema Associated with Central Retinal Vein Occlusion A Report by the American Academy of Ophthalmology [J].2015,122(4). (wanfangdata.com.cn)
Choroidal Volume in Branch Retinal Vein Occlusion before and after Intravitreal Anti-Vegf Injection [J].2015,35(6). (wanfangdata.com.cn)

Subretinal pigment epithelium choroidal neovascularization was noted in four (3.96%) eyes. (bvsalud.org)
Such eyes had thickened choroid and fewer cases had associated choroidal neovascularization. (bvsalud.org)
Regression analysis of the change in VA as a function of choroidal neovascularization (CNV) type did not show any linear trend. (jamanetwork.com)
A, B, and C, Preoperative fluorescein angiograms (early, middle, and late phases, respectively) of the left eye of a 63-year-old male patient demonstrating classic subfoveal choroidal neovascularization (visual acuity, 20/80). (jamanetwork.com)
Patient had had surgical excision of recurrent choroidal neovascularization 6 months after full macular translocation. (jamanetwork.com)
Macular Photocoagulation Study Group, Visual outcome after laser photocoagulation for subfoveal choroidal neovascularization secondary to age-related macular degeneration. (jamanetwork.com)
Treatment of Age-Related Macular Degeneration With Photodynamic Therapy (TAP) Study Group, Photodynamic therapy of subfoveal choroidal neovascularization in age-related macular degeneration with verteporfin: one-year results of 2 randomized clinical trials, TAP report 1. (jamanetwork.com)
It oc-curs less frequently in the set-ting of vitreoretinal traction, choroidal neovascularization and a number of other con--ditions. (reviewofophthalmology.com)

The choroid is a vascular network providing the bulk of the oxygen and nutrient supply to the retina and may play a pivotal role in retinal disease pathogenesis. (arvojournals.org)
On ICGA, the intense choroidal vascular hyperpermeability (CVH) group displayed a greater BPD than the nonintense CVH group. (bvsalud.org)
The macula lutea, which derives its name from the deposition of yellow xanthophyll pigments (see chapter on Simple Anatomy), is located temporal to the optic disc and is bounded by the temporal superior and inferior vascular arcades (Fig. 1). (org.es)
Some distinct changes in the retinal microvasculature are recognized as the preindicator of subsequent vascular incidents like ischemic stroke or acute stroke [ 10 ]. (hindawi.com)
Angiogenesis is a contributing factor in some retinal diseases, hence the role of vascular endothelial growth factor (VEGF) as a common pathway in proliferative retinopathies. (openophthalmologyjournal.com)

UWF retinal photo of the top (A) and bottom (B) eye showing a tessellated fundus, tilted nerve with temporal crescent. (reviewofoptometry.com)
however, the patient's best corrected visual acuity (BCVA) recovered only to 0.7 OD and 0.6 OS, and the impairment of the outer retinal layer was broadly detected as hyperautofluorescent lesions on fundus autofluorescence (FAF) examination and as irregularity in or disappearance of the ellipsoid and interdigitation zones on OCT, which were quite atypical for the findings of APMPPE. (bvsalud.org)
The merging of the images obtained by these three wavelengths should be able to detect findings from the different retinal layers much more clearly than conventional color fundus images. (biomedcentral.com)
One of the most important subfields of biomedical engineering is the analysis of fundus retinal images. (hindawi.com)
Analysis of the human fundus eye images has become the key point for diagnosing the various pathologies of retinal vasculature. (hindawi.com)
The fundus retinal images are directly captured from human eye that includes some other landmarks like microcirculation system of the retina, macula, optic disc, fovea, microaneurysm, and exudates [ 4 ]. (hindawi.com)

Approximately 40-50% of patients with GCA have ophthalmologic complications, including visual loss secondary to A-AION, central retinal artery occlusion, homonymous hemianopsia or cortical blindness (uni- or bilateral occipital infarction) [ 6 ]. (intechopen.com)

Characteristic to the disease is the profound atrophy of the brain accompanied by amyloid-beta (Aβ) plaques and the presence of tau neurofibrillary tangles (NFTs). (frontiersin.org)
H and I, Fluorescein angiogram at 75 months (visual acuity, 20/320) (note the retinal pigment epithelium atrophy extending toward the new fovea). (jamanetwork.com)

While optical coherence tomography angiography provides an en face depiction of the choroidal vasculature, it does not reveal flow dynamics. (arvojournals.org)
Pachychoroid spectrum disorder (PCD) is a group of disorders characterized by chronic choroid thickening and dysfunction of choroidal vasculature. (cjeo-journal.org)

The investigative team from Turkey found chronic rhinosinusitis appears to cause thinning of the choroid and retinal nerve fiber layer (RNFL), especially in the superior and inferior quadrants and ganglion cell-inner plexiform layer (GCIPL). (reviewofoptometry.com)
The optic nerve contains the ganglion cell axons running to the brain and, additionally, incoming blood vessels that open into the retina to vascularize the retinal layers and neurons (Fig. 1.1). (org.es)
A radial section of a portion of the retina reveals that the ganglion cells (the output neurons of the retina) lie innermost in the retina closest to the lens and front of the eye, and the photosensors (the rods and cones) lie outermost in the retina against the pigment epithelium and choroid. (org.es)
The retinal message concerning the photic input and some preliminary organization of the visual image into several forms of sensation are transmitted to the brain from the spiking discharge pattern of the ganglion cells. (org.es)
The retinal nerve fiber layer (RNFL) is the innermost layer of the retina and consists of the axons of the retinal ganglion cells (RGCs). (biomedcentral.com)
Neural signals from the rods and cones undergo processing by other neurons, whose output takes the form of action potentials in retinal ganglion cells whose axons form the optic nerve. (wikipedia.org)

314 eyes of 274 patients with PCD including 149 eyes of 113 patients with central serous chorioretinopathy (CSC), 95 eyes of 81 patients with polypoid choroidal vasculopathy (PCV), 70 eyes of 60 patients with neovascular age-related macular degeneration (nAMD), along with 382 eyes of 199 normal subjects matched diopter, age and gender with PCD were selected for likelihood ratio analysis. (cjeo-journal.org)

Ocular manifestations of chronic rhinosinusitis should be taken in consideration during the management of this disease, the researchers noted. (reviewofoptometry.com)
Karakahya RH, Korkmaz M, Korkmaz H. Decreased retinal nerve fiber and choroidal thickness in chronic rhinosinusitis. (reviewofoptometry.com)
Alzheimer's disease (AD) is a chronic, progressive neurodegenerative disease leading to severe cognitive loss and eventual death. (frontiersin.org)
Chronic Granulomatous Disease can affect the fetus in utero and present as congenital abnormalities Congenital Abnormalities Malformations of organs or body parts during development in utero. (lecturio.com)
Purpose: The purpose of this study was to investigate and compare the corresponding alterations of the pupillary response between acute and chronic central serous chorioretinopathy (CSC) and between different disease categories. (bvsalud.org)
Helical collagen structures play an important cell signaling role in healthy tissues and they are damaged in chronic and acute/traumatic disease processes and injuries. (ois.net)
Stuart was founded in 2018 to champion a new approach to the treatment of chronic diseases. (ois.net)
Each of our founders has been affected directly or indirectly by chronic eye disease, and we have a passion for the pursuit of new and effective solutions for these indications. (ois.net)
Chronic disease is treated with tear supplements, warm compresses, and occasionally oral antibiotics (eg, a tetracycline or azithromycin) for meibomian gland dysfunction or with eyelid hygiene and tear supplements for seborrheic blepharitis. (merckmanuals.com)
Objectives: This study aimed to investigate and compare sleep quality between patients with chronic temporomandibular disorder and healthy controls, and to analyze the association of sleep quality with disease characteristics, obstructive sleep apnea risk factors, and excessive daytime sleepiness. (preprints.org)

The ophthalmologist van der Hoeve was the first to describe the phakomatoses as a clinical entity of diseases including tuberous sclerosis, neurofibromatosis, and von Hippel-Lindau and Sturge-Weber syndromes [ 11 ]. (hindawi.com)

Cystoid macular edema (CME) in 2 eyes and significant retinal inflammation in 4 eyes were markedly resolved after single injection. (bvsalud.org)

That group chose to honor his legacy by accepting case reports from optometric residents across the country relating to vitreoretinal disease. (reviewofoptometry.com)

respiratory compromise secondary to cerebrovascular accident, respiration failure secondary to neurological diseases (i.e. (reviewofoptometry.com)

MacLaren REBird ACSathia PJAylward GW Long-term results of submacular surgery combined with macular translocation of the retinal pigment epithelium in neovascular age-related macular degeneration. (jamanetwork.com)
Ninomiya YLewis JMHasegawa TTano Y Retinotomy and foveal translocation for surgical management of subfoveal choroidal neovascular membranes. (jamanetwork.com)

The anterior part of the body of the fornix, the choroid plexus, lateral dorsal surface of the thalamus, stria terminalis, and caudate nucleus, form the floor of the lateral ventricle. (medscape.com)
Capillaries of the choroid arteries from the pia mater project into the ventricular cavity, forming the choroid plexus of the lateral ventricle (see the image below). (medscape.com)
The choroid plexus is attached to the adjacent brain structures by a double layer of pia mater called the tela choroidea. (medscape.com)
The choroid plexus extends from the lateral ventricle into the inferior horn. (medscape.com)
As imaging with FFA is limited with only superficial capillary plexus (SCP), OCTA is superior over FFA in terms of its use in the diagnosis of diseases that affect deep capillary plexus (DCP). (ekjo.org)

6 Sandwiched between the retinal pigment epithelium (RPE) and the sclera, the choroid is approximately 0.22- to 0.3-mm thick at the posterior pole, thinning anteriorly. (arvojournals.org)
Excessive axial length elongation drives biomechanical stretching of the posterior globe often associated with retinal and choroidal changes that inevitably lead to severe and irreversible visual impairment. (reviewofoptometry.com)
The previously reported posterior pole findings appreciated via dilated fundoscopy were as follows: treated retinal tear with old cryotherapy and new barrier laser scars (12:30) in the right eye, and treated retinal tears (11:00, 1:30) with pigmented lattice degeneration (5:00-6:00), all surrounded by barrier laser in the left eye. (reviewofoptometry.com)

The incidence of lymphoproliferative ocular diseases, especially malignant lymphoma, has increased over the years. (medscape.com)
Adverum Biotechnologies (NASDAQ: ADVM) is a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the aspiration of developing functional cures for these diseases to restore vision and prevent blindness. (ois.net)
By overcoming the challenges associated with current treatment paradigms for these debilitating ocular diseases, Adverum aspires to transform the standard of care, preserve vision, and create a profound societal impact around the globe. (ois.net)

The patient had an extensive ocular history with regards to retinal changes related to PM. She underwent barrier laser retinopexy of retinal tears in both eyes approximately twelve years prior with re-treatment ten years later for additional laser barricade around the retinal tears in addition to inferior lattice degeneration in her left eye. (reviewofoptometry.com)

We scanned both eyes of 12 healthy subjects in a horizontal plane superior to the optic nerve head using an 18-MHz linear array. (arvojournals.org)
The blue wavelength light does not penetrate deeper than the retinal nerve fiber layer and can be used to study the inner layers of the retina. (biomedcentral.com)
therefore, the optic nerve must cross through the retina en route to the brain. (wikipedia.org)

The choroidal thickness of different macular regions was compared by independent sample t-test. (wanfangdata.com.cn)

We measured the choroidal thickness of thyroid-associated ophthalmopathy (TAO) patients in different stages using swept-source optical coherence tomography (SS-OCT) and found that the choroidal thickness of TAO patients in the active phase increased significantly. (bmj.com)
Baseline optical coherence tomography (OCT), and fluorescein and indocyanine green angiography (FA/ICGA) were performed to analyze the relationship between pupillary response and retinal/choroidal architecture. (bvsalud.org)
The choroidal thickness of macular area was measured by enhanced deep imaging technique of frequency domain optical coherence tomography. (wanfangdata.com.cn)
11]Mrejen,S.,Spaide,R.F.. Optical coherence tomography: Imaging of the choroid and beyond [J].2013,58(5). (wanfangdata.com.cn)
Optical coherence tomography angiography (OCTA) is a new imaging technique that enables detailed imaging of retinal veining by obtaining movement contrast of the erythrocytes in vessels through consecutive optic coherence tomography screenings of a specific retinal area. (ekjo.org)

In the normal eye, fluorescein is prevented from passing into the retina by the blood-retinal barriers. (reviewofophthalmology.com)

In both groups, the choroidal thickness was the thickest in the central area, gradually thinning to the nasal side and temporal side, and the nasal choroidal thickness was thinner than other regions, and N6 area was the thinnest. (wanfangdata.com.cn)

The average thickness of the rhinosinusitis patients' RNFL overall and in the superior and inferior quadrants was significantly lower compared with the control group. (reviewofoptometry.com)
Since the initial description of the disease by Nozik and Dorsch in 1973, hundreds of patients have been reported in the literature with multifocal choroiditis and panuveitis (MCP). (medscape.com)
Many patients with dry AMD are asymptomatic and unaware of the disease. (org.es)
Conclusion:The choroidal thickness of macular area in patients with BRVO-ME is thicker than that in normal subjects. (wanfangdata.com.cn)
Patients with retinal diseases who had ocular examination with both the MC-SLO and CF instruments at the Kagoshima University from December 2016 to February 2017 were studied. (biomedcentral.com)

This group of rare disorders involves a primary pathologic process occurring at or near the level of the retinal pigment epithelium (RPE) with or without photoreceptor outer segment and choriocapillaris involvement. (medscape.com)

This technique can be used to monitor the progression of the disease and to evaluate the response to treatment. (ekjo.org)

Present study intended to analyze the clinical presentation, risk factors, choroidal features, and outcome of CMD in CSCR. (bvsalud.org)
The green wavelength scanning light penetrates into the retina and can be used to analyze the deeper layers of the retina, and the red wavelengths scanning light can reach the retinal pigment epithelium (RPE) and the superficial choroid and can be used to study the RPE and choroid. (biomedcentral.com)
Various diagnostic techniques are used to analyze retinal microvasculature image to enable geometric features measurements such as vessel tortuosity, branching angles, branching coefficient, vessel diameter, and fractal dimension. (hindawi.com)

446 eyes of 230 healthy subjects from the pachychoroid spectrum disorder (PCD) cohort in Beijing Tongren Hospital were enrolled for the choroidal thickness distribution analysisfrom April 2018 to June 2021. (cjeo-journal.org)
According to the study of [ 12 ] with a multiethnic cohort, retinal arteriolar narrowing and retinopathy of diabetic free people have an association with increased risk of acute stroke. (hindawi.com)
Rotterdam cohort study also came into a decision after a long-term observation that the retinal venular diameter is associated with any stroke or ischemic stroke [ 14 ]. (hindawi.com)

Furthermore, glaucoma and thickened choroid, linked to the port-wine stain, are recurrent ocular findings in all three conditions. (hindawi.com)

The phakomatoses have been traditionally defined as a group of hereditary diseases with variable expressivity characterized by multisystem tumors with possible malignant transformation. (hindawi.com)

Eyelid eversion is used to expose the superior palpebral conjunctiva and fornix, so that foreign matter can be identified in these areas. (merckmanuals.com)

Its outer surface is in contact with the choroid and the inner surface with the vitreous body. (lecturio.com)
4, 5, 6, 7, 8] AMN, a bilateral condition affecting otherwise healthy young adults, appears to involve a pathologic process occurring more in the middle and outer retinal layers rather than in the RPE and choriocapillaris. (medscape.com)
Five days later, the hyperfluorescence on FAF had disappeared, and the outer retinal layer improved on OCT. Moreover, the patient's BCVA recovered to 1.0 OU. (bvsalud.org)
Macular edema represents the pathologic accumulation of extracellular fluid within the retina, primarily in the outer plexiform and inner nuclear layers, as a nonspecific re-sponse to a breakdown in the blood-retinal barriers. (reviewofophthalmology.com)

Outcome of transplantation of autologous retinal pigment epithelium in age-related macular degeneration: a prospective trial. (jamanetwork.com)

Objective To characterize the distribution characteristics of choroidal thickness in healthy normal subjects and to define the diagnostic cut-off value for pachychoroid. (cjeo-journal.org)

This paper will also review recent research on the image processing-based extraction techniques of the quantitative retinal microvascular feature. (hindawi.com)
FA provides no quantitative information re-garding retinal thickening. (reviewofophthalmology.com)

The diagnosis of GCA requires age more than 50 years at disease onset, new headache in the temporal area, temporal artery tenderness, and/or reduced pulse, jaw claudication, systemic symptoms, erythrocyte sedimentation rate (ESR) exceeding 50 mm/hr, and typical histologic findings (granulomatous involvement) in temporal artery biopsy (TAB) [ 5 ]. (intechopen.com)

Other features linked to the port-wine stain and typical to all of the three conditions are glaucoma and choroidal alterations. (hindawi.com)
Stuart's areas of interest are Dry Eye Disease, Glaucoma, and Dry Age-Related Macular Degeneration. (ois.net)

While the central retinal artery provides the inner retina's blood supply, most of its oxygen demand is supplied by diffusion from the underlying choroid (which is the sole supply of the avascular fovea), which is in turn supplied by the ciliary arteries. (arvojournals.org)
Central retinal thickness (CFT) in all eyes without CME, ellipsoid zone (EZ) on OCT in 71.4% of eyes, ERG response in 55% of eyes, and VF in 50% of eyes were stable or improved within 6 months after treatment. (bvsalud.org)
As such, integrins are central to the etiology and pathology of many disease states. (thno.org)
Rima Fuad Jubran, MD, MPH, MACM is medical director of the Retinoblastoma Program in the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles, where she cares for children with central nervous system tumors, retinoblastoma and neuroblastoma. (sc-ctsi.org)

To observe the distribution characteristics of choroidal thickness in different regions of two groups of eyes. (wanfangdata.com.cn)

ME is a frequent cause of vision loss in pa-tients with diabetes mellitus, retinal venous oc-clusion, uveitis, and following in--traocular surgery. (reviewofophthalmology.com)

Ischemic Infarcts of the Choroid (Elschnig Spots): A Cause of Retinal Separation in Hypertensive Disease with Renal Insufficiency: A Clinical and Histopathologic Study [J].1968,66(6). (wanfangdata.com.cn)

The images obtained by MC-SLO are superior to that obtained by CF in detecting NFLDs in eyes with retinal diseases. (biomedcentral.com)
We recommend MC-SLO imaging to screen for NFLDs in eyes with retinal diseases. (biomedcentral.com)
Squid eyes do not have an analog of the vertebrate retinal pigment epithelium (RPE). (wikipedia.org)

Various pathophysiological mechanisms have been proposed, but the clinical similarities, ophthalmic manifestations in particular, make it reasonable to classify these diseases as an independent group. (hindawi.com)
Stuart Therapeutics (Stuart) is a clinical stage biopharmaceutical company focused on the development of a unique tissue reparative platform for eye diseases called PolyColTM (PolyCol). (ois.net)

Anatomy22

Organisms1

Diseases23

Chemicals and Drugs6

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Psychiatry and Psychology1

Phenomena and Processes4

Subfoveal choroidal thickness5

Serous retinal detachment3

Diabetic retinopathy7

Detachment4

Vein occlusion5

Neovascularization8

Vascular5

Fundus6

Occlusion1

Atrophy2

Vasculature2

Ganglion6

Vasculopathy1

Chronic10

Tuberous sclerosis1

Cystoid1

Vitreoretinal1

Secondary1

Neovascular2

Plexus5

Posterior3

Ocular diseases3

Lattice Degeneration1

Nerve3

Macular regions1

Coherence tomography5

Fluorescein1

Thinner1

Patients5

Photoreceptor1

Progression1

Analyze3

Cohort3

Recurrent1

Hereditary1

Fornix1

Outer4

Outcome1

Diagnostic1

Quantitative2

Diagnosis1

Glaucoma2

Central4

Characteristics1

Diabetes1

Spots1

Eyes3

Clinical2