• Treximet ( sumatriptan and naproxen sodium) is a combination of a headache medicine and a nonsteroidal anti-inflammatory drug ( NSAID ) used to treat migraine headaches. (rxlist.com)
  • Treximet is a tablet with a fixed dose combination of 85 mg sumatriptan and 500 mg naproxen sodium. (rxlist.com)
  • Our Treximet (sumatriptan and naproxen sodium) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. (rxlist.com)
  • TREXIMET is a combination of sumatriptan, a serotonin (5-HT) 1b/1d receptor agonist (triptan), and naproxen sodium, a non-steroidal anti-inflammatory drug, indicated for the acute treatment of migraine with or without aura in adults and pediatric patients 12 years of age and older. (nih.gov)
  • Known hypersensitivity to sumatriptan, naproxen, or any components of TREXIMET (angioedema and anaphylaxis seen). (nih.gov)
  • Sumatriptan, sold commonly under brand names Imitrex and Treximet among others, is a medication used to treat migraine headaches and cluster headaches. (wikipedia.org)
  • The article features Treximet, a combination of sumatriptan and naproxen, used for migraine. (davidhealy.org)
  • Behind Treximet lies trials comparing the combination to sumatriptan alone and to naproxyn alone and to placebo showing some benefit it seems - if these trials can be believed. (davidhealy.org)
  • Wherever you buy sumatriptan, you can try to simulate the effect of Treximet by taking naproxen sodium (Aleve) along with it. (thedailyheadache.com)
  • See paragraph five of Save Money on Sumatriptan (Imitrex/Imigran/Treximet) for details. (thedailyheadache.com)
  • Serious cardiac events, including some that have been fatal, have occurred following the use of sumatriptan injection or tablets. (wikipedia.org)
  • Sumatriptan is administered in several forms: tablets, subcutaneous injection, and nasal spray. (wikipedia.org)
  • Since March 2021, sumatriptan 50mg tablets are available without a prescription at pharmacies (packets of 2 tablets only). (headacheaustralia.org.au)
  • Our range of products include tendovir and disopronil fumarate and emticitabine tablets, pirfinedone pirfenex tablet, oxybutynin chloride tablets oxynine 5 mg, candesartan 16 mg tablets candistrum, sumatriptan naproxen tablets and cinitapride cintodac capsul. (edmedsindia.com)
  • Sumatriptan belongs to a class of drugs called triptans. (universaldrugstore.com)
  • Sumatriptan belongs to a group of medications known as triptans, which influence a specific natural substance called serotonin. (candrugstore.com)
  • Nonsteroidal antiinflammatory drugs (NSAIDs) such as ibuprofen and naproxen, as well as ergotamine and sumatriptan and other triptans, may be given to stop migraines. (carle.org)
  • Sumatriptan is part of a class of medications called 'triptans', which belong to a group of drugs called serotonin agonists. (headacheaustralia.org.au)
  • Sumatriptan belongs to a class of drugs called 'triptans', which are acute medications developed specifically to treat migraine pain. (headacheaustralia.org.au)
  • Sumatriptan and other triptans only work for head pain, and can't be used to treat other conditions. (headacheaustralia.org.au)
  • Of all the triptans, sumatriptan has the greatest flexibility in how it is administered. (headacheaustralia.org.au)
  • Naproxen is known as a nonsteroidal anti-inflammatory drug (NSAID). (universaldrugstore.com)
  • Do not take an NSAID such as naproxen if you have recently had a heart attack, unless directed to do so by your doctor. (medlineplus.gov)
  • Naproxen is classified as a nonsteroidal anti-inflammatory drug (NSAID) and is employed for pain relief. (candrugstore.com)
  • Although most research examines the combined use of sumatriptan and naproxen - another type of NSAID - the authors of a 2019 article suggest that people can combine the triptan with a rapid-acting NSAID. (medicalnewstoday.com)
  • Responders rates were highest for nasal and oral zolmitriptan, oral eletriptan and subcutaneous sumatriptan. (bvsalud.org)
  • Sumatriptan is molecularly similar to serotonin (5-HT), and is a 5-HT receptor (types 5-HT1D and 5-HT1B) agonist. (wikipedia.org)
  • Serotonin is responsible for constricting blood vessels in the brain, and sumatriptan may also provide pain relief by affecting certain nerves within the brain. (candrugstore.com)
  • A selective agonist for serotonin 5-HT1 receptors, naratriptan has higher bioavailability and a longer half-life than sumatriptan, which may contribute to a lower rate of headache recurrences. (medscape.com)
  • People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as naproxen may have a higher risk of having a heart attack or a stroke than people who do not take these medications. (medlineplus.gov)
  • However, a person should avoid taking ibuprofen with similar medications, such as aspirin or naproxen . (medicalnewstoday.com)
  • Naproxen-containing products should not be used by patients who have had allergic reactions to any product containing naproxen, nor in patients with asthma and nasal polyps in whom aspirin or other NSAIDs may induce an exacerbation of asthma. (salesandmarketingnetwork.com)
  • NSAIDs such as naproxen may cause ulcers, bleeding, or holes in the esophagus (tube between the mouth and stomach), stomach, or intestine. (medlineplus.gov)
  • The risk may be higher for people who take NSAIDs for a long time or at higher doses, are older in age, have poor health, who smoke, or who drink large amounts of alcohol while taking naproxen. (medlineplus.gov)
  • other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn) while you are using ketorolac. (nih.gov)
  • Prior to using this product, inform your doctor or pharmacist about any allergies you may have, such as allergies to naproxen, sumatriptan, aspirin, other NSAIDs, or any other substances. (candrugstore.com)
  • Sumatriptan is used to treat migraine and can be taken orally in tablet form, as a nasal spray and as an injection. (headacheaustralia.org.au)
  • Sumatriptan 20mg nasal spray is also accessible through the PBS to people with migraine whose migraine symptoms have usually failed to respond to analgesics in the past. (headacheaustralia.org.au)
  • Nonsteroidal anti-inflammatory drugs (including naproxen) may rarely increase the risk for a heart attack or stroke. (universaldrugstore.com)
  • Medication less likely to cause MOH are hydroxyzine, metoclopramide and low-dose non-steroidal anti-inflammatory drugs such as ibuprofen and naproxen. (sunshinentc.com)
  • Dr Loder has made public statements favourable to GSK products, including: 'For all of these reasons my mantra is that "You haven't failed sumatriptan until you have failed to respond to a full dose of injectable sumatriptan given early in an attack! (davidhealy.org)
  • In addition to migraine, the injectable forms of sumatriptan are used to treat cluster headache - a relatively rare and extremely painful type of headache that has symptom and treatment overlaps with migraine (1). (headacheaustralia.org.au)
  • Injected sumatriptan is more effective than other formulations. (wikipedia.org)
  • This paradox has, to some extent, been resolved by comparing the rates of absorption of the various sumatriptan formulations, rather than the absolute amounts of drug that they deliver. (wikipedia.org)
  • The efficacy of sumatriptan is 82% at 20 minutes when administered by injection, 52-62% at 2 hours when administered intranasally, and 67-79% at 4 hours when administered orally. (medscape.com)
  • Overdose of sumatriptan can cause sulfhemoglobinemia, a rare condition in which the blood changes from red to green, due to the integration of sulfur into the hemoglobin molecule. (wikipedia.org)
  • Sumatriptan works by constricting (narrowing) these blood vessels, thereby relieving the migraine headaches. (edmedsindia.com)
  • The trials were run by GlaxoSmithKline, for whom sumatriptan had been a flagship drug for decades, and Pozen Inc. Once concluded, in 2014 GSK transferred the rights to Pernix. (davidhealy.org)
  • Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with prescription naproxen and each time you refill your prescription. (medlineplus.gov)
  • Prescription naproxen is used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), juvenile arthritis (a form of joint disease in children), and ankylosing spondylitis (arthritis that mainly affects the spine). (medlineplus.gov)
  • Sumatriptan is metabolised primarily by monoamine oxidase A into 2-{5-[(methylsulfamoyl)methyl]-indole-3-yl}acetic acid, which is then conjugated to glucuronic acid. (wikipedia.org)
  • Naproxen is not recommended for use during the last 3 months of pregnancy due to possible harm to the fetus and interference with normal labor/delivery. (rxlist.com)
  • Sumatriptan is effective for ending or relieving the intensity of migraine and cluster headaches. (wikipedia.org)
  • Sumatriptan is also shown to decrease the activity of the trigeminal nerve, which presumably accounts for sumatriptan's efficacy in treating cluster headaches. (wikipedia.org)
  • When injected, sumatriptan is faster-acting (usually within 10 minutes), but the effect lasts for a shorter time. (wikipedia.org)
  • If you experience any of the following symptoms, stop taking naproxen and call your doctor: stomach pain, heartburn, vomit that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools. (medlineplus.gov)
  • Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to naproxen. (medlineplus.gov)