• Solvents
  • Inactivation of the virus also occurs under the following conditions: 30 minutes 60 °C (140.0 °F) (half-hour at a temperature that causes first and second degree burns in humans in ten seconds) Acidic pH conditions Presence of oxidizing agents such as sodium dodecyl sulfate, lipid solvents, and B-propiolactone Exposure to disinfectants: formalin, iodine compounds Ordinary levels of chlorine in tap water kill H5N1 in public water systems. (wikipedia.org)
  • sodium
  • The capsule shell is composed of titanium dioxide, gelatin, sodium lauryl sulphate and the printing ink contains: shellac, propylene glycol, strong ammonia solution, black iron oxide and potassium hydroxide. (nih.gov)
  • influenza
  • Amantadine, a well known drug used in influenza as well as movement disorder of Parkinson, has been proved to improve various other types of movement disorder as ataxia, chorea, dystonia, akinesia and attention span. (clinicaltrials.gov)
  • Amantadine inhibits the replication of influenza A virus isolates from each of the subtypes, i.e. (nih.gov)
  • A quantitative relationship between the in vitro susceptibility of influenza A virus to amantadine and the clinical response to therapy has not been established in man. (nih.gov)
  • Sensitivity test results, expressed as the concentration of amantadine required to inhibit by 50% the growth of virus (ED 50 ) in tissue culture vary greatly (from 0.1 mcg/mL to 25.0 mcg/mL) depending upon the assay protocol used, size of virus inoculum, isolates of influenza A virus strains tested, and the cell type used. (nih.gov)
  • Influenza A variants with reduced in vitro sensitivity to amantadine have been isolated from epidemic strains in areas where adamantane derivatives are being used. (nih.gov)
  • shown
  • Although amantadine has not been shown to possess direct anticholinergic activity in animal studies, clinically, it exhibits anticholinergic-like side effects such as dry mouth, urinary retention, and constipation. (nih.gov)