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AlbendazoleAnthelminticsAnticestodal AgentsMebendazoleSulfonesEchinococcosisIvermectinDiethylcarbamazineEchinococcosis, HepaticEchinococcusSulindacEchinococcus granulosusFilaricidesPraziquantelAscariasisTrichuriasisAscaris lumbricoidesElephantiasis, FilarialSulfoxidesHelminthiasisAntiparasitic AgentsAntinematodal AgentsHookworm InfectionsTrichurisFenbendazoleNeurocysticercosisWuchereria bancroftiEncephalitozoonosisStrongyloidiasisStrongylidaParasite Egg CountIntestinal Diseases, ParasiticEncephalitozoonAntiplatyhelmintic AgentsTaeniaEchinococcosis, PulmonaryCysticercosisStrongyloides stercoralisHelminthsAntiprotozoal AgentsLarva MigransDapsoneNematode InfectionsEye Infections, ParasiticFilariasisLoiasisMicrofilariaThiabendazoleTaenia soliumSkin Diseases, ParasiticAngiostrongylus cantonensisAncylostomatoideaEncephalitozoon cuniculiGnathostomaMicrosporidaAntibodies, HelminthTrichinellosisDrug Therapy, CombinationStrongylida InfectionsFecesStrongyloidesMicrosporidiosisGiardia lambliaCentral Nervous System Helminthiasis

SulfoxideBroad-spectrum anthelminticAlbenzaStudy of albendazolePrimary metaboliteAnthelminticMetabolitesABZSO2Pork tapewormTapeworm infectionsSulphoxideAlbendazolumArtemisininNeurocysticercosisParasitesThiabendazoleTablet containsIntestinalPregnantVeterinaryMetabolismLiverDrugsPreventsPraziquantelPregnancyEggsClinicalRoundwormWormsEliminationTreatmentFormMedicineTime

Sulfoxide7

• A sensitive and selective HPLC chromatography method using UV detection (295 nm) was developed for the determination of albendazole, albendazole sulfoxide (ABZSO), and albendazole sulfone (ABZSO2) in human plasma. (tmu.edu.tw)
• Rapidly converted in the liver to the primary metabolite, albendazole sulfoxide, which is further metabolized to albendazole sulfone and other primary oxidative metabolites that have been identified in human urine. (drugbank.com)
• Urinary excretion of albendazole sulfoxide is a minor elimination pathway with less than 1% of the dose recovered in the urine. (drugbank.com)
• Biliary elimination presumably accounts for a portion of the elimination as evidenced by biliary concentrations of albendazole sulfoxide similar to those achieved in plasma. (drugbank.com)
• The oxidation of albendazole on gold electrode surface yielded albendazole sulfoxide and albendazole sulfone which are the main metabolites of this drug in vivo. (rowan.edu)
• Albendazole sulfoxide is secreted into breast milk at around 1.5% of the maternal dose, though oral absorption is poor enough that it is unlikely to affect nursing infants. (worldsbest.rehab)
• In the body metabolism after class for sulfoxide or sulfone, inhibition of parasites on the absorption of glucose, lead to the insect body glycogen depletion, or inhibition of fumaric acid reductase system, prevent the generation of ATP, the parasite can survive and reproduce. (nmn-powder.com)

Broad-spectrum anthelmintic2

• Albendazole is a broad-spectrum anthelmintic and antiprotozoal agent of the benzimidazole type. (wikipedia.org)
• Albendazole is a broad-spectrum anthelmintic. (drugbank.com)

Albenza2

• The medication Albenza (albendazole) belongs to a class of drugs called anthelmintics. (curezone.org)
• Generic Albenza (Albendazole) 400mg is available in packs of 30, 60, 90, 120 and 240 pills. (curezone.org)

Study of albendazole1

• The method appears to be robust and has been applied to a pharmacokinetic study of albendazole in healthy volunteers. (tmu.edu.tw)

Primary metabolite1

• It is metabolized in a liver with formation of primary metabolite of albendazole of the sulphoxide having anthelminthic activity. (rxeli.com)

Anthelmintic2

• Albendazole is a benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections. (drugbank.com)
• Albendazole is an anthelmintic or anti- worm medication. (nmn-powder.com)

Metabolites1

• Kitzman, D, Cheng, KJ & Fleckenstein, L 2002, ' HPLC assay for albendazole and metabolites in human plasma for clinical pharmacokinetic studies ', Journal of Pharmaceutical and Biomedical Analysis , vol. 30, no. 3, pp. 801-813. (tmu.edu.tw)

ABZSO24

• Albendazole, ABZSO, ABZSO2, and the internal standard, oxibendazole, were extracted from human plasma by loading onto a conditioned C 18 SPE cartridge, rinsing with 15% methanol, and eluting with 90% methanol. (tmu.edu.tw)
• The assay was linear for concentration ranges in human plasma of 20-600 ng/ml for albendazole, 20-1000 ng/ml for ABZSO, and 20-300 ng/ml for ABZSO2. (tmu.edu.tw)
• Albendazole, ABZSO, ABZSO2, and the internal standard, oxibendazole, were extracted from human plasma by loading onto a conditioned C18 SPE cartridge, rinsing with 15% methanol, and eluting with 90% methanol. (tmu.edu.tw)
• Mother plasma and embryo concentrations of ABZSO enantiomers and albendazole sulphone (ABZSO2) were determined 9 h after administration. (uab.cat)

Pork tapeworm3

• Cysticercosis (especially neurocysticercosis), which is caused by the larval form of the pork tapeworm (i.e. albendazole is the drug of choice for larval pork tapeworms, but not adult pork tapeworms). (wikipedia.org)
• Though albendazole is effective in treating many diseases, it is only FDA-approved for treating hydatid disease caused by dog tapeworm larvae and neurocysticercosis caused by pork tapeworm larvae. (worldsbest.rehab)
• Albendazole is used to treat certain infections caused by worms such as pork tapeworm and dog tapeworm. (nmn-powder.com)

Tapeworm infections1

• Though praziquantel is often better at treating tapeworm infections, albendazole is used more often in endemic countries due to being cheaper and having a broader spectrum. (wikipedia.org)

Sulphoxide6

• Time of achievement of Cmax of albendazole of sulphoxide is 2-5 h. (rxeli.com)
• Albendazole sulphoxide is metabolized in albendazole sulphone (secondary metabolite) and other oxidized products. (rxeli.com)
• After reception of a single dose of 400 mg pharmacological an active metabolite - sulphoxide of albendazole reaches plasma concentration from 1.6 to 6.0 µmol/l. (rxeli.com)
• At damage of a liver the bioavailability increases, at this Cmax of albendazole of sulphoxide increases twice, and elimination half-life is extended. (rxeli.com)
• abstract = "Three single oral doses (8.5, 10, and 14 mg/kg) of a racemic formulation of albendazole sulphoxide (ABZSO) were administered to pregnant rats on day 10 of gestation. (uab.cat)
• Albendazol's removal sulphoxide in a liver turns into an albendazol sulphone (secondary metabolite) and other oxidized products. (rxeli.com)

Albendazolum1

• Albendazole, also known as albendazolum, is a medication used for the treatment of a variety of parasitic worm infestations. (mzfoodtest.com)

Artemisinin1

• This work is aimed to investigate the metabolic behavior of albendazole and artemisinin. (rowan.edu)

Neurocysticercosis3

• People receiving albendazole for the treatment of neurocysticercosis can have neurological side effects such as seizures, increased intracranial pressure, and focal signs caused by the inflammatory reaction that occurs when parasites in the brain are killed. (worldsbest.rehab)
• Steroids and anticonvulsants are often given with albendazole when treating neurocysticercosis to avoid these effects. (worldsbest.rehab)
• Those being treated for retinal neurocysticercosis can face retinal damage if they are not first checked for ocular cysticeri, since changes to existing lesions in the eye by albendazole can cause permanent blindness. (worldsbest.rehab)

Parasites1

• Alveolar and cystic echinococcosis may require lifelong treatment with albendazole, which only prevents the parasites from growing and reproducing rather than killing them. (wikipedia.org)

Thiabendazole1

• Albendazole has a similar efficacy to thiabendazole, but fewer side effects. (wikipedia.org)

Tablet contains1

• Each tablet contains 400 mg albendazole. (who.int)

Intestinal3

• A single dose of albendazole is sufficient to treat intestinal infestations by A. duodenale or Necator americanus. (wikipedia.org)
• Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by diminishing its energy production, ultimately leading to immobilization and death of the parasite. (drugbank.com)
• Pharmacokinetics Later properties of oral administration albendazole is badly adsorbed from a gastro intestinal path (less than 5%), in not changed look the bioavailability - low is not defined in plasma. (rxeli.com)

Pregnant2

• While studies in pregnant rats and rabbits have shown albendazole to be teratogenic, albendazole has been found to be safe in humans during the second and third trimesters. (worldsbest.rehab)
• In pregnant dogs, albendazole use has led to puppies with reduced weight and with cleft palates. (worldsbest.rehab)

Veterinary1

• The detection of veterinary drug residues such as albendazole in raw milk is of great concern for the dairy industry because of the potential interfering and adverse effects of antibiotic residues frequently found in raw milk. (mzfoodtest.com)

Metabolism1

• The metabolism of Albendazole can be increased when combined with Abatacept. (drugbank.com)

Liver3

• The most common side effects of albendazole are experienced by over 10% of people and include headache and abnormal liver function. (worldsbest.rehab)
• Albendazole is used for prophylaxis and treatment of worm infections in calves, cattle, goats and sheep like: gastronintestinal worms, lung worms, tapeworms, liver-fluke. (nmn-powder.com)
• Caution should be used if [NT005 trade name] is given to patients with liver disease, since albendazole is metabolised by the liver and has been associated with idiosyncratic hepatotoxicity. (who.int)

Drugs3

• It can increase the anxiety and depression a person experiences, and it can interact with certain other drugs including Albendazole. (worldsbest.rehab)
• It is important to remember that interactions do occur with all types of drugs, to a great or lesser extent and this article details the interactions of mixing Albendazole and Weed. (worldsbest.rehab)
• Albendazole has been included in the world health organization's list of essential medicines and is one of the most important basic health drugs. (nmn-powder.com)

Prevents1

• The Albendazole powder prevents newly hatched insect larvae (worms) from growing or multiplying in your body. (nmn-powder.com)

Praziquantel1

• Albendazole is an effective treatment for: Flatworms Fasciolosis Cestodes (tapeworms), as an alternative to praziquantel or niclosamide for adult beef tapewormss and as an alternative to praziquantel for pork tapeworms. (wikipedia.org)

Pregnancy1

• Albendazole is a pregnancy class D drug in Australia. (worldsbest.rehab)

Eggs1

• Birds have lower rates of laying eggs and hatching when given albendazole. (worldsbest.rehab)

Clinical1

• Albendazole is an effective and low - toxic broad-spectrum insect repellent.Clinical use can be used to drive roundworm, pinworm, tapeworm, whipworm, hookworm, dung beetle, etc. (nmn-powder.com)

Roundworm1

• 4. Albendazole is applied to get rid of roundworm, pinworm, hookworm, whipworm, can also be used for deworming livestock. (nmn-powder.com)

Worms1

• Albendazole is effective against adult worms but not against the immature microfilariae. (wikipedia.org)

Elimination1

• Elimination half-life of albendazole makes 8.5 h. (rxeli.com)

Treatment1

• Albendazole can achieve good results (95%-100% efficacy after a 10-day course of treatment) if treatment is initiated within 72 hours of ingestion of the egg-containing raccoon feces. (wikipedia.org)

Form1

• It is removed with bile through intestines in the form of albendazole of a sulfoksid and only an insignificant part of its quantity is removed with urine. (rxeli.com)

Medicine1

• Albendazole is an imidazole derivative broad-spectrum insect repellent medicine, which was discovered by glaxosmithkline's animal health laboratory in 1972. (nmn-powder.com)

Time1

• Samples were collected at 3 time points: after each of 2 treatments with albendazole and after resettlement in the United States. (cdc.gov)