Subtypes leiomyoma microscopic leiomyoma epithelioid. Medical search. Frequent questions

Uterine leiomyoma must be differentiated from other diseases that cause uterine mass, such as: uterine adenomyoma , pregnancy , hematometra , uterine sarcoma , uterine carcinosarcoma, and metastasis . (wikidoc.org)
Common risk factors in the development of uterine leiomyoma include African-American race, early menarche , prenatal exposure to diethylstilbestrol , having one or more pregnancies extending beyond 20 weeks, obesity , significant consumption of beef and other red meats, hypertension , family history , and alcohol consumption. (wikidoc.org)
The mainstay of therapy for uterine leiomyoma is oral contraceptive pills , either combination pills or progestin-only , Gonadotropin-releasing hormone analogs . (wikidoc.org)
Surgery is also part of mainstay therapy for uterine leiomyoma. (wikidoc.org)

Microscopic examination of the pelvic mass showed a biphasic tumor composed of epithelial and mesenchymal components, suggestive of synovial sarcoma. (ochsnerjournal.org)
The morphology axis addresses the microscopic structure (histology) of the tumor. (wikipedia.org)

These tumors are usually more than 5 cm in their greatest dimension, but a uterine mass of any size that has features different from the usual whorled, white, cut surface of a leiomyoma should be sampled. (medscape.com)
It is thought that leiomyoma is the result of either transformation of normal uterine muscle cells into abnormal cells through somatic mutations , or through the growth of abnormal uterine muscle cells into tumors. (wikidoc.org)

In appearance, leiomyosarcomas of the uterus have features that range from those similar to leiomyoma (rare) to overtly malignant, gross features similar to those of high-grade sarcomas that may occur anywhere in the body, with infiltrative edges, necrosis, hemorrhage, and a variegated cut surface. (medscape.com)

they range from benign leiomyomas to low-grade and high-grade leiomyosarcomas . (medscape.com)
The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)

On gross pathology , round, well circumscribed, non-encapsulated, solid white or tan nodules , and whorled are characteristic findings of leiomyoma. (wikidoc.org)
On microscopic histopathological analysis, elongated and spindle-shaped cells with a cigar-shaped nucleus are characteristic findings of leiomyoma. (wikidoc.org)

The leiomyoma/myometrial interface is smooth and very well circumscribed (see the image below). (medscape.com)

Leiomyoma is more commonly observed among patients aged 40 years and older. (wikidoc.org)

they range from benign leiomyomas to low-grade and high-grade leiomyosarcomas. (medscape.com)
Leiomyomas and leiomyosarcomas are believed to develop independently and are not progressive. (medscape.com)
In appearance, leiomyosarcomas of the uterus have features that range from those similar to leiomyoma (rare) to overtly malignant, gross features similar to those of high-grade sarcomas that may occur anywhere in the body, with infiltrative edges, necrosis, hemorrhage, and a variegated cut surface. (medscape.com)
The purpose of this study was to distinguish leiomyosarcomas/smooth muscle tumors of uncertain malignant potential (STUMP) from leiomyomas with high signal intensity (SI) on T2-weighted imaging (T2WI) using quantitative MR texture analysis combined with patient characteristics and visual assessment. (bvsalud.org)
Thirty-one leiomyomas, 2 STUMPs, and 6 leiomyosarcomas showing high SI on T2WI were included. (bvsalud.org)
First, we searched for differences in patient characteristics and visual assessment between leiomyomas and leiomyosarcomas/STUMPs. (bvsalud.org)
We also compared the MR texture on T2WI and the apparent diffusion coefficient (ADC) to identify differences between leiomyomas and leiomyosarcomas/STUMPs. (bvsalud.org)
In the past, these tumors were presumed to have elements of smooth muscle (smooth muscle origin), so they were classified as leiomyomas, leiomyosarcomas and leiomyoblastomas [ 3 ]. (biomedcentral.com)

The belief that the risk of ULMS is elevated among women with a "rapidly growing" uterus or leiomyoma was proven false in a study of 1322 women admitted to two community hospitals for hysterectomy or myomectomy . (sarcomahelp.org)

Submucosal leiomyomas occur within the myometrium. (medscape.com)
PDGFRA-mutant GISTs are usually epithelioid and occur predominantly in the stomach. (nih.gov)

CT , MRI , and ultrasound are used in combination with biopsy to distinguish between the types and subtypes of germ cell tumors and for diagnosis confirmation. (wikidoc.org)