• With the continuous scaling down of metal-oxide-semiconductor field-effect transistors (MOSFETs), Si-based MOSFET is approaching its physical and technical limitation. (springer.com)
  • The RJ-EVs showed satisfactory anti-inflammatory and antioxidant effects, and significantly promoted L929 cell proliferation and migration in vitro . (thno.org)
  • Both gain-of-function and loss-of-function experiments have unequivocally demonstrated that overexpression of KLF7 promotes the growth and metastasis of COAD in vitro and in vivo , while KLF7 knockdown attenuated these effects. (ijbs.com)
  • The combination of this new composite with sonication was applied for rapid and efficient adsorption of Bromocresol Purple (BCP). (researcher-app.com)
  • The aim of the study is to prepare aqueous dispersions of lipid nanoparticles - flurbiprofen solid lipid nanoparticles (FLUSLN) and flurbiprofen nanostructured lipid carriers (FLUNLC) by hot homogenization followed by sonication technique and then incorporated into the freshly prepared hydrogels for transdermal delivery. (biomedcentral.com)
  • The functional neuroprotective effect was assessed with electroretinography at 6, 9, and 12 weeks old. (molvis.org)
  • Neuroprotective effects can be achieved by several pathways. (molvis.org)
  • Subsequently, secreted PDGFB facilitates the progression of COAD by activating MAPK/ERK, PI3K/AKT, and JAK/STAT3 signaling pathways through PDGFRβ. (ijbs.com)
  • The RJ is an essential nutritional food for the growth, development and metabolism of queen bees and bee larvae [ 12 - 14 ], in humans it is often used in traditional medicine and natural health products due to its anti-bacterial, anti-inflammatory, anti-tumor and antioxidant effects [ 15 ]. (thno.org)
  • Anti-inflammatory effect in the Carrageenan-induced paw edema in rat was significantly higher for B1 and A1 formulation than the orally administered flurbiprofen. (biomedcentral.com)
  • This modification prospects to a loss of positive charge, reduction in hydrogen-bonding ability and subsequently in conformational and functional changes of the protein. (healthanddietblog.info)
  • We also observed that the peaks within the refragmented sample have an extended shoulder location (which is why the peakshave develop into wider), that is once more explicable by the fact that iterative sonication introduces the longer fragments in to the evaluation, which would have already been discarded by the conventional ChIP-seq process, which doesn't involve the extended fragments in the sequencing and subsequently the analysis. (glucagon-receptor.com)
  • Evaluation reports on specifications developed subsequently to the original set of specifications are added in a chronological order to this report. (who.int)
  • Importantly, the neurorestorative effects of LIPUS on CCH-induced damages were totally reversed by knockdown the expression of hippocampal Fndc5 in WT mice, or in F5KO mice. (biomedcentral.com)
  • Importantly, no adverse effects were observed in the compound-treated mice, including no change in white blood cell counts as is often observed in cancer patients receiving high doses of MT-stabilizing drugs. (biomedcentral.com)
  • T-cell depletion and reconstitution experiments showed that the effect was absolutely dependent upon the presence in the cultures of T cells from these seropositive donors. (nih.gov)
  • The goal of this study was to investigate the effect of the environmental conditions such as the temperature change, incubation time and surface type on the resistance of Staphylococcus aureus biofilms to disinfectants. (researchgate.net)
  • Effects of initial BCP concentration, mass of adsorbent and sonication time on response were investigated and optimized by central composite design (CCD). (researcher-app.com)
  • Analysis of variation (ANOVA) was adapted to experimental data to find best optimum conditions which was set at 15.22 mg L −1 , 2.41 min, 0.02 g and 0.009 mg for initial BCP concentration, sonication time and adsorbent mass, respectively. (researcher-app.com)
  • In order to exploit the pharmacological potential of natural bioactive molecules with low water solubility, such as curcumin, it is necessary to develop formulations, such as amorphous polymer dispersions, which allow a constant release rate and at the same time avoid possible toxicity effects of the crystalline form of the molecule under scrutiny. (ibecbarcelona.eu)
  • Transcranial LIPUS was applied 24 h after BCAS and subsequently daily with a stimulation time of 5 min at an ultrasound pressure of 0.51 MPa for a period of 28 days. (biomedcentral.com)
  • Examples include limiting agitation procedures such as sonication, or by using a lower-temperature process in chemical reactors to minimize release of materials in exhaust. (wikipedia.org)
  • It reveals that the thickness of the barrier layer has a strong effect on the bacterial reduction of the fabrics. (nature.com)
  • These substances act in different ways, exerting overall protective effects against many diseases, especially skin disorders. (ibecbarcelona.eu)
  • Aqueous samples may be extracted with trichlorotrifluoroethane, while solid samples may be extracted by Soxhlet extraction or sonication methods (Air Force 1989). (cdc.gov)
  • Reaction of 1,4-phenylenedioxy diacetic acid with zinc salt leads to the formation of [Zn(C 10 H 8 O 6 )(H 2 O) 4 ] n and subsequently was loaded on activated carbon following sonication and structurally characterized by FTIR, SEM, EDX and XRD analysis. (researcher-app.com)
  • The RJ-EVs can be gradually released from the SerMA hydrogel at the wound site, ensuring the restorative effect of RJ-EVs. (thno.org)
  • Mechanistically, we evidenced that GCN5L1 could acetylate TFAM at its K76 site and subsequently inhibited its binding to TOM70, thereby reducing TFAM import into mitochondria and mitochondrial biogenesis. (biomedcentral.com)
  • Data were subsequently analysed and processed using Meta-Disc. (biomedcentral.com)
  • Problems with the model were soon seen when experimental data was compared to the numerical solution where variables that were initially not taken into the account showed a much greater effect than first anticipated. (um.si)
  • Hence ?while the aforementioned effects are also present, such as the increased size and significance of the peaks ?this information set showcases the merging impact extensively: nearby peaks are detected as one particular, since the extended shoulders fill up the separating gaps. (glucagon-receptor.com)
  • An attempt was made to explain how enhancement of CMCs values made crystallite size decreased and subsequently lattice strain increased. (nanochemres.org)
  • It is assumed that SLN and NLC, when administered directly onto skin in a small but sufficient quantity, would cause less side effects, if any, than the currently available formulations. (biomedcentral.com)
  • Ultrasound equipment is found in nearly all hospitals in the US, and ultrasound imaging is highly versatile and possesses few if any side effects. (thno.org)
  • However, the medicinal use of comfrey is limited by the hepatotoxic effect of lycopsamine in comfrey, which overshadows the health benefits of rosmarinic acid. (frontiersin.org)
  • Health effects from noise can be controlled by purchasing or renting less noisy equipment. (wikipedia.org)
  • Section 104(i)(5) of CERCLA, as amended, directs the Administrator of ATSDR (in consultation with the Administrator of EPA and agencies and programs of the Public Health Service) to assess whether adequate information on the health effects of Stoddard solvent is available. (cdc.gov)
  • Where adequate information is not available, ATSDR, in conjunction with NTP, is required to assure the initiation of a program of research designed to determine the health effects (and techniques for developing methods to determine such health effects) of Stoddard solvent. (cdc.gov)
  • Furthermore, there were differences in methylation patterns that, although not statistically significant, demonstrate the potential effects of PEPs on the overall epigenome following exposure. (nih.gov)
  • Here, we investigated the activity and efficacy of Fndc5/irisin in experimental VaD, further explored whether the potential effects of LIPUS on VaD is related to Fndc5/irisin. (biomedcentral.com)
  • Howeternally, studies are required on higher sensual correspondence and subsequently on human subjects to prove clinical efficacy of naproxen as an antinociceptive and anxiolytic and extra fact-finding is legend to find unconfined the practical side so to speaks that it may provide because of significant metal of chelation and its principles responsible an veneration to such activity. (upb.ro)
  • One well-known example occurred when dichloromethane was phased out as a brake cleaner due to its environmental effects, but its replacement n-hexane was subsequently found to be neurotoxic. (wikipedia.org)
  • We saw how strong these effects can be, immediate, acute effects, and Keith was showing specificity in targeting and cell type, and also showing that there might be certain spaces or certain areas in the parameter space that are more effective. (nih.gov)
  • You laid the foundations and showed us how really strongly founded in physical effects, but it also showed all of us that these strong physical underpinnings really have a complexity, that there's a mixture of effects that we might not be entirely sure how everything is working, and which effects are the most prominent ones. (nih.gov)
  • Additionally, Isoniazid (apart from Rifampicin the most potent first-line anti-TB drug) has only a limited effect on M. avium , 9 and relapses are common. (who.int)
  • This features a good effect on smaller peaks: these mark ra.Peaks that have been unidentifiable for the peak caller within the manage information set become detectable with reshearing. (glucagon-receptor.com)
  • Nevertheless, the blockade effect from physiological barriers and unwanted uptake by the reticuloendothelial system impede the application of exogenous nano-systems [ 2 , 3 ]. (thno.org)
  • 100 °C) reaction kinetics are enhanced, heat and water management in the fuel cell systems is simplified, and the effect of impurities in hydrogen causing catalyst poisoning are mitigated. (rsc.org)
  • Recently new agents have shown promising effects in symptom improvement and fibroid regression, like aromatase inhibitors, mifepristone, selective estrogen receptor modulators, and selective progesterone receptor modulators. (hindawi.com)
  • Edge effects are sometimes seen because the fluid must form droplets at the edge to be thrown off. (ossila.com)
  • Prompt and effective monitoring and control of invasive species is essential to prevent them from spreading and causing harmful effects. (cdc.gov)