Subgingival dental diseases biofilm oral fusobacterium. Medical search. Frequent questions

Porphyromonas gingivalis Fusobacterium nucleatum is found between the early and late colonisers, linking them together. (wikipedia.org)
Species including Filifactor alocis and Fusobacterium nucleatum were central to this network, which supports their role in the coaggregation of periodontal biofilms during disease progression. (ox.ac.uk)
A model multi-species sub-gingival community containing Fusobacterium nucleatum, Streptococcus constellatus , Parvimonas micra with wild type or isogenic mutants of P. gingivalis was then created and growth and proteolytic activity in serum assessed as above. (biomedcentral.com)
A. oris induces the coaggregation of the early colonizers Streptococcus gordonii and Streptococcus sanguinis with the intermediate colonizer Fusobacterium nucleatum in oral biofilms [ 1 ]. (biomedcentral.com)

Literature data have reported that certain Gram-negative anaerobe bacteria from the subgingival environment are important etiological agents of chronic periodontal disease. (journal-imab-bg.org)
Periodontal diseases: diagnosis. (journal-imab-bg.org)
3. Tetradis S, Carranza F, Fazio R, Takei H. Radiographic aids in the diagnosis of periodontal disease. (journal-imab-bg.org)
5. Loomer PM. Microbiological diagnostic testing in the treatment of periodontal diseases. (journal-imab-bg.org)
The role of inflammatory mediators in the pathogenesis of periodontal diseases. (journal-imab-bg.org)
10. Haffajee A, Sokransky S. Microbial etiological agents of destructive periodontal diseases. (journal-imab-bg.org)
Relationships among gingival crevicular fluid biomarkers, clinical parameters of periodontal disease, and the subgingival microbiota. (journal-imab-bg.org)
Our findings show that the stress hormone cortisol directly induces shifts in the gene expression profiles of the oral microbiome that reproduce results found in the profiles of expression of periodontal disease and its progression. (nature.com)
UNLABELLED: Periodontal disease ranges from gingival inflammation (gingivitis) to the inflammation and loss of tooth-supporting tissues (periodontitis). (ox.ac.uk)
Quantitative modeling of bacterial abundances across the natural range of periodontal severities can distinguish which features of disease are associated with particular changes in composition. (ox.ac.uk)
We assessed a cross-sectional cohort of 962 Malawian women for periodontal disease and used 16S rRNA gene amplicon sequencing (V5 to V7 region) to characterize the bacterial compositions of supragingival plaque samples. (ox.ac.uk)
IMPORTANCE: Periodontal disease is a major public health problem associated with oral bacteria. (ox.ac.uk)
However, previous high-throughput marker gene sequencing studies of supragingival plaque have largely focused on high-income populations with good oral hygiene without including a range of periodontal disease severities. (ox.ac.uk)
Periodontitis is a chronic inflammatory disorder of infectious etiology involving the hard and soft periodontal tissues and which is related to various systemic disorders, including cardiovascular diseases, diabetes and obesity. (mdpi.com)
The current article aims to review the beneficial role of some probiotic species, their mode of action and clinical effectiveness especially in periodontal disease and halitosis. (bvsalud.org)
Dental caries, periodontal disease and halitosis are among the oral disorders that have been targeted. (bvsalud.org)
Researches show that 80% of dogs over the age of 3 suffer from some form of periodontal disease. (vin.com)
periodontal treatment costs totaled $51 billions in North America in 2003, 75% of all dental costs. (vin.com)
In other word, periodontal disease is irreversible and incurable, only controllable. (vin.com)
As the research done by Dr. L. Debowes determined, the signs can also be associated with disease to the organs affected by periodontal disease (heart, kidney, liver, skin, lungs and brain). (vin.com)
It has also been shown that periodontal disease interacts with endocrine conditions such as diabetes mellitus, hyperthyroidism and hypothyroidism. (vin.com)
Subgingival scaling is the simplest of the periodontal procedure and is virtually done at every dental cleaning. (vin.com)
In periodontitis, however, the development of periodontal pockets as a result of breakdown of the bone and soft-tissues supporting the teeth, creates a new subgingival niche that promotes growth of bacterial species suited to the environment. (biomedcentral.com)
It was shown that 40-50% of plaque remains after tooth brushing, and the effects of biofilm retention are clearly evident in the prevalence of caries, gingivitis and periodontal disease. (encyclopedia.pub)
Periodontal diseases include two main conditions: gingivitis and periodontitis. (encyclopedia.pub)
While the more severe forms of periodontal disease associated with alveolar bone loss are less frequent, gingivitis is widespread at all ages and is the most common form of periodontal disease. (encyclopedia.pub)
#Streptococcus salivarius K12 and M18 prevented immune activation induced by periodontal disease pathogens. (metabiom.org)
Periodontal disease is more common in individuals with #Rheumatoid Arthritis (RA) who have detectable anti-citrullinated protein antibodies (ACPAs). (metabiom.org)
Patients with RA and periodontal disease experienced repeated oral bacteremias associated with transcriptional signatures of specific monocytes, recently identified in inflamed RA synovia and blood of those with RA flares. (metabiom.org)
Some members of the genera #Porphyromonas , #Prevotella , and #Tannerella are well-known pathogens of the oral cavity, where they can notably cause periodontal disease and dental #Caries . (metabiom.org)
This is one of the most abundant spirochetes, found in sites with severe periodontal destruction and associated with periodontal disease . (metabiom.org)
Isolates were obtained from patients with periodontal or peri-implant diseases and confirmed by sequencing their 16S rRNA gene. (bvsalud.org)
95% of people with diabetes also have periodontal disease. (intownsmilestudio.com)
Diabetics with periodontal disease have more difficulty controlling their blood sugar level. (intownsmilestudio.com)
The Oral Microbiology Testing Service (OMTS) Laboratory at the Kornberg School of Dentistry provides commercial diagnostic testing services to practicing dentists and several dental school clinical programs in the U.S. The OMTS Laboratory is licensed by the Pennsylvania Health Department for clinical periodontal microbiology analysis. (temple.edu)
These services are focused on microbial culture and antibiotic susceptibility testing of dental plaque/biofilm sampled from patients with periodontal disease or failing dental implants. (temple.edu)

Metronidazole is effective against obligate anerobes such as Porphyromonas spp , Prevotella spp , Bacteroides spp , Fusobacterium spp , and Clostridium spp . (dentistryiq.com)
A small number of species were associated with periodontitis but not gingivitis, including members of Prevotella, Treponema, and Selenomonas, supporting a more complex disease model than a linear progression following gingivitis. (ox.ac.uk)

The bulk of the microorganisms that form the biofilm are Streptococcus mutans and other anaerobes, though the precise composition varies by location in the mouth. (wikipedia.org)
Streptococcus mutans was previously considered a primary cause, but recent research promotes the ecologic hypothesis, in which a dysbiosis in the oral microbial community leads to caries. (researchsquare.com)

Dental plaque is a biofilm of microorganisms (mostly bacteria, but also fungi) that grows on surfaces within the mouth. (wikipedia.org)
Bacteria then attach to the pellicle layer, form micro-colonies, and mature on the tooth, which can result in oral diseases. (wikipedia.org)
The following table provides a more detailed (six-step) explanation of biofilm formation: Different types of bacteria are normally present in the mouth. (wikipedia.org)
These bacteria, as well as leukocytes, neutrophils, macrophages, and lymphocytes, are part of the normal oral cavity and contribute to the individual's health. (wikipedia.org)
Below is a summary of the bacteria that may be present during the phases of plaque maturation: Early biofilm: primarily Gram-positive cocci Older biofilm (3-4 days): increased numbers of filaments and fusiforms 4-9 days undisturbed: more complex flora with rods, filamentous forms 7-14 days: Vibrio species, spirochetes, more Gram-negative organisms Dental plaque is considered a biofilm adhered to the tooth surface. (wikipedia.org)
After some growth of early colonisers, the biofilm becomes more compliant to other species of bacteria, known as late colonisers. (wikipedia.org)
8. Salari MH, Kadkhoda Z. Rate of cultivable subgingival periodontopathogenic bacteria in chronic poeriodontitis. (journal-imab-bg.org)
Bacteria have always been associated with disease and have caused the human race much grief. (bvsalud.org)
Formation of dental Pellicle Acquired enamel pellicle forms rapidly - Early pellicle Characterized by an absence of bacteria and their products. (medicpresents.com)
If not removed regularly, the biofilm undergoes maturation, which is connected with a progressive shift from a Gram-positive to a Gram-negative anaerobic species, which results in formation under the gingival surface, where bacteria grow profusely [ 1 ] . (encyclopedia.pub)
Periodontitis is a complex, chronic inflammatory disease caused by an abnormal host response to bacteria from dental plaque. (encyclopedia.pub)
In patients with AD, oral bacteria were detected in brain tissues, and increased levels of pro-inflammatory cytokines were also detected. (metabiom.org)
The oral bacteria observed transiently in blood were broadly citrullinated in the mouth, and their in situ citrullinated epitopes were targeted by extensively somatically hypermutated ACPA B Cells encoded by RA blood plasmablasts. (metabiom.org)
Actinomyces oris is an early colonizer and has two types of fimbriae on its cell surface, type 1 fimbriae (FimP and FimQ) and type 2 fimbriae (FimA and FimB), which contribute to the attachment and coaggregation with other bacteria and the formation of biofilm on the tooth surface, respectively. (biomedcentral.com)
Short-chain fatty acids (SCFAs) are metabolic products of oral bacteria including A. oris and regulate pH in dental plaques. (biomedcentral.com)
SCFAs affect the INAC-associated activities of the A. oris fimbrillins and non-fimbrillins during ionized and non-ionized acid formations in the form of co-culturing with other bacteria in the dental plaque but not impact the interaction of A. oris with streptococci. (biomedcentral.com)
Gum disease bacteria can be found in the brains of Alzheimer's patients. (intownsmilestudio.com)
having a healthy oral biofilm (your mouth has only the good bacteria) is protective against developing pancreatic cancer. (intownsmilestudio.com)
To survive in the oral habitat, T. forsythia depends on cohabiting bacteria for the provision of nutrients. (karger.com)
This report summarizes T. forsythia 's strategies to survive in the oral habitat by means of PGN salvage pathways, including recovery of exogenous MurNAc and PGN-derived fragments but also polymeric PGN, which are all derived from cohabiting bacteria either via cell wall turnover or decay of cells. (karger.com)

These microorganisms all occur naturally in the oral cavity and are normally harmless. (wikipedia.org)
An essential condition for a microorganism to represent a probiotic of interest for oral health is its capacity to adhere to and colonize various surfaces of the oral cavity. (bvsalud.org)
Definition Dental Plaque "is a specific but highly variable structural entity, resulting from sequential colonization of microorganisms on tooth surfaces, restorations & other parts of oral cavity, composed of salivary components like mucin, desquamated epithelial cells, debris & microorganisms, all embedded in extracellular gelatinous matrix. (medicpresents.com)
The human oral microbiome refers to an ecological community of symbiotic and pathogenic microorganisms found in the oral cavity. (encyclopedia.pub)
The oral cavity is an environment that provides various biological niches, such as the teeth, tongue, and oral mucosa. (encyclopedia.pub)
The oral cavity is the gateway between the external environment and the human body, maintaining oral homeostasis, protecting the mouth, and preventing disease. (encyclopedia.pub)
Oral cavity and the composition of oral microbiome. (encyclopedia.pub)
The human oral cavity is a highly complex ecosystem in which the tooth- and soft-tissue surfaces offer distinct ecological niches for microbial colonization. (biomedcentral.com)
The oral cavity is particularly susceptible to viral infections that are self-recovering in most cases. (bvsalud.org)
CPC-containing mouthwashes have been used as antiseptics for decades, and thus, they can represent a cost-effective measure to limit infection and spread of enveloped viruses infecting the oral cavity, aiding in reducing viral transmission. (bvsalud.org)
Adverse microbial changes, both in composition and function, can act at several levels within the gut (stool and mucosal) and have also been described in the blood and oral cavity. (jci.org)
While dysbiosis in the oral cavity could be a source of systemic inflammation, current cirrhosis treatment modalities are targeted toward the gut-liver axis and do not address the oral microbiome. (jci.org)

Oral hygiene is important as dental biofilms may become acidic causing demineralization of the teeth (also known as dental caries) or harden into dental calculus (also known as tartar). (wikipedia.org)
Early childhood caries (ECC) - dental caries (cavities) occurring in primary teeth up to age 6-years - is a prevalent childhood oral disease with a microbial etiology. (researchsquare.com)
The pathogenic bacterial complex can lead to dental caries, periodontitis and gingivitis. (encyclopedia.pub)
In another report, the maximum concentrations of butyric (8.8 mM), propionic (33.7 mM), acetic (52.6 mM) and formic acids (5.8 mM) were also detected in dental plaques from caries-free and caries-susceptible young subjects [ 32 ]. (biomedcentral.com)

Microbiological data has been suggested by several studies as a useful indicator of disease progression, selection of an adjunctive antimicrobial administration, healing assessment and disease recurrence. (journal-imab-bg.org)
It is therefore critically important to define the microbiome of healthy persons in order to detect significant variations both in disease states and in pre-clinical conditions to understand disease onset and progression. (biomedcentral.com)
There is a growing body of scientific evidence that suggests the potential implication of periodontitis in the causation and progression of various systemic disease and conditions, such as diabetes, cardiovascular disease, pulmonary disease, adverse pregnancy outcomes and cancer. (intechopen.com)
Cirrhosis development and progression involves several important interorgan communications, and recently, the gut microbiome has been implicated in pathophysiology of the disease. (jci.org)
As interventions designed to modulate oral dysbiosis may delay progression of cirrhosis, a better understanding of this process is of the utmost importance. (jci.org)

Periodontitis is a highly prevalent, chronic multifactorial infectious disease, induced by the dysbiotic biofilm that triggers a persistent systemic inflammation and recurrent bacteremia. (intechopen.com)
Dysbiotic subgingival communities are characterized by a relative increase in abundance of anaerobic, Gram-negative bacterial species that can exploit protein-rich GCF as a nutrient source, promoting development of a proteolytic community phenotype. (biomedcentral.com)
Similar to the effect of gut microbiota on cirrhosis, emerging evidence also suggests that there is a possible link between a dysbiotic oral microenvironment and liver diseases. (jci.org)

Imbalances of the microbiome, also referred to as microbial dysbiosis, could lead to a series of different diseases. (nature.com)
We used a metatranscriptomic approach to obtain first insights into the metabolic changes induced by this stress hormone as well as which members of the oral microbiome respond to the presence of cortisol in the environment. (nature.com)
Among the environmental factors that may alter the equilibrium in host-microbiome homeostasis, host-stress is a known risk factor for a variety of diseases. (nature.com)
Experimental evidence shows that the microbiome is needed for the health of the host and that alterations in the ecological equilibrium of microbes can lead to disease. (bvsalud.org)
To understand the relationship between our bacterial microbiome and health, it is essential to define the microbiome in the absence of disease. (biomedcentral.com)
The bacterial microbiome of the human digestive tract contributes to both health and disease. (biomedcentral.com)
Oral Microbiome Related Diseases" Encyclopedia , https://encyclopedia.pub/entry/12380 (accessed December 11, 2023). (encyclopedia.pub)
The aim of this review article is to highlight the role of gut microbiome and inflammation in the pathophysiology of cirrhosis and to introduce the oral-gut-liver axis as a new perspective to consider in future research. (jci.org)

The abundance of #Porphyromonadaceae and #Fusobacterium , which are co-pathogens in periodontitis and intestinal inflammation was significantly enriched in the gut of the C-SP group. (metabiom.org)

When the adjacent gingival soft-tissues are inflamed, the flow of serum-like transudate (gingival crevicular fluid, GCF) into the pocket increases and under the influence of this environmental perturbation, homeostasis in the subgingival microbial community can be disturbed giving rise to dysbiosis that predisposes the site to disease [ 3 ]. (biomedcentral.com)

Dental plaque is also known as microbial plaque, oral biofilm, dental biofilm, dental plaque biofilm or bacterial plaque biofilm. (wikipedia.org)
Bacterial plaque is one of the major causes for dental decay and gum disease. (wikipedia.org)
Our study includes a large number of low-income participants with poor oral hygiene and a wide range of severities, and we were therefore able to quantitatively model bacterial abundances as functions of both gingivitis and periodontitis. (ox.ac.uk)
The widespread emergence of bacterial resistance to antibiotics has led to the concept of probiotic therapy for application in oral health. (bvsalud.org)
Dental plaque is a community of microorganisms found on the surface of teeth or other hard surfaces like dentures and embedded in a matrix of polymers of both host and bacterial origin. (encyclopedia.pub)

A biofilm is a multilayered microbiological ecosystem that adheres to the surface of a structure and confers greater protection from antibiotics and an immune response vs. the planktonic microbiota alone. (dentistryiq.com)

Aim: Our aim was to compare the prevalence and load of nine pathobionts in subgingival samples of healthy individuals and periodontitis patients from four different countries. (bvsalud.org)
Methods: Five hundred and seven subgingival biofilm samples were collected from healthy subjects and periodontitis patients in Belgium, Chile, Peru and Spain. (bvsalud.org)
Based on this, F. alocis, P. endodontalis, P. gingivalis, T. denticola and T. forsythia may be biomarkers of disease in Belgium, Chile and Spain, due to their significantly higher abundance in periodontitis patients. (bvsalud.org)

Tannerella forsythia is an anaerobic, fusiform Gram-negative oral pathogen strongly associated with periodontitis, a multibacterial inflammatory disease that leads to the destruction of the teeth-supporting tissue, ultimately causing tooth loss. (karger.com)
Only recently insights were obtained into how T. forsythia gains access to MurNAc in its oral habitat, enabling synthesis of the own PGN cell wall. (karger.com)

The recruitment criteria included a set of objective, composite measurements performed by healthcare professionals [ 10 ], defining this reference population and enabling this investigation to focus on defining the integrated oral, oropharyngeal, and gut microbiomes in the absence of host disease. (biomedcentral.com)

Check out this medical presentation on Dental Calculus, which is titled "Dental Plaque", to know about the difference between dental plaque, calculus , and materia alba, types of plaque, composition of plaque, and formation of plaque. (medicpresents.com)
Rams, T.E., Alwaqyan, A.Y. In vitro performance of DIAGNOdent laser fluorescence device for dental calculus detection on human tooth root surfaces. (temple.edu)

It is commonly found between the teeth, on the front of teeth, behind teeth, on chewing surfaces, along the gumline (supragingival), or below the gumline cervical margins (subgingival). (wikipedia.org)
Dental plaque is a biofilm that attaches to tooth surfaces, restorations and prosthetic appliances (including dentures and bridges) if left undisturbed. (wikipedia.org)
Tooth-associated communities were distinct, but not entirely dissimilar, from other oral surfaces. (biomedcentral.com)
May involve the interaction of phosphate groups with calcium ions in saliva to form "bridges" Protective functions of early enamel pellicle: protection , lubrication by decreasing frictional forces, may selectively concentrate antimicrobial substances such as immunoglobulins, lysozyme, and cystatins at different oral surfaces. (medicpresents.com)
Most of them attach to different surfaces to form some type of biofilm matrix that is highly structured and spatially organized. (encyclopedia.pub)

In addition, dental biofilm, especially subgingival plaque in patients with periodontitis, has been associated with cardiovascular and respiratory disease and diabetes mellitus, and recently constituting a high risk for developing severe illness due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection [ 2 ] . (encyclopedia.pub)
The disease caused by SARS-CoV-2 infection was named Coronavirus Disease 2019 (COVID-19). (encyclopedia.pub)

The inhibition of quorum sensing, called quorum quenching, may disrupt oral biofilm formation, which is the main etiological factor of oral diseases, including periodontitis. (mdpi.com)

These data provide a critical baseline for future studies investigating local and systemic diseases affecting human health. (biomedcentral.com)

In this article, he cites studies that explain the various antibiotics prescribed for periodontitis, and the effects they have on biofilms and clinical treatment modalities. (dentistryiq.com)
3 The purpose of this article is to better understand the antibiotics that are prescribed for periodontitis, and what effects they have on biofilms and clinical treatment modalities. (dentistryiq.com)

2 This is most likely due to the fact that the penetration of the antibiotics into the biofilm was low and that there is higher resistance in the biofilm. (dentistryiq.com)
9 Systemic antibiotics help prevent recolonization and reorganization of the biofilm after the biofilm has been disrupted. (dentistryiq.com)

Together in the subgingival consortium however, all the included species were able to grow in the serum environment and the community adopted a proteolytic phenotype. (biomedcentral.com)

Several etiologies, with the most prevalent being viral hepatitis, alcoholic liver disease (ALD), and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (NAFLD/NASH), can cause cirrhosis. (jci.org)

Probiotics have proven to be effective in the treatment of several systemic and infectious diseases such as acute diarrhoea, Crohn's disease, cancer, immunodepressive states, inadequate lactase digestion, hyperlipidemia, liver diseases, infections with Helicobacter pylori, genitourinary tract infections and others 12 . (bvsalud.org)

Genera with pathogenic members were well-represented among this disease-free cohort. (biomedcentral.com)

Dental plaque, which leads to oral diseases, may be a risk factor causing a severe course of COVID-19 similar to those in above mentioned chronic diseases. (encyclopedia.pub)

Patients suffering from diabetes, hypertension, obesity, asthma, and kidney and liver disease are in the high-risk group for severe COVID-19 symptoms [ 6 ] . (encyclopedia.pub)
therefore, this review will highlight the emerging role of the oral-gut-liver axis and introduce perspectives for future research. (jci.org)
NAFLD is a spectrum of liver disease associated with metabolic syndrome and obesity that consists of simple fatty infiltration (steatosis), inflammation with steatosis (steatohepatitis or NASH), and varying degrees of fibrosis that ultimately lead to cirrhosis. (jci.org)

Previous research has focused mainly on subgingival plaque, but supragingival plaque composition is also known to be associated with disease. (ox.ac.uk)
However, even after controlling for gingivitis, the presence of subgingival periodontitis was associated with an altered supragingival plaque. (ox.ac.uk)

No matter what stage your patient is in, the first treatment step is to perform a complete dental cleaning. (vin.com)
Currently, the lack of robust tools to identify the individuals with a high degree of risk for tooth loss means that even people who may not develop severe disease undergo intensive treatment, placing a significant burden on healthcare budgets in the developed world. (biomedcentral.com)
Tissue injury, flossing, dental treatment and even chewing and eating can induce blood vessel injury near spaces covered in dental plaque. (encyclopedia.pub)
Therefore, it is important to understand the pathogenesis of cirrhosis and the underlying biological factors that can modulate disease outcomes to develop better preventive and treatment strategies. (jci.org)

Dysbiosis in subgingival microbial communities, resulting from increased inflammatory transudate from the gingival tissues, is an important factor in initiation and development of periodontitis. (biomedcentral.com)

Anatomy7

Organisms28

Diseases33

Chemicals and Drugs9

Analytical, Diagnostic and Therapeutic Techniques and Equipment25

Psychiatry and Psychology2

Phenomena and Processes5

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena5

Technology, Industry, Agriculture3

Information Science1

Named Groups6

Health Care22

Nucleatum4

Periodontal36

Prevotella2

Streptococcus2

Bacteria20

Cavity12

Caries4

Progression5

Dysbiotic3

Microbiome8

Pathogens1

Microbial community1

Bacterial5

Microbiota1

Periodontitis patients3

Forsythia2

Microbiomes1

Calculus2

Surfaces5

Infection2

Quorum1

Systemic diseases1

Clinical2

Antibiotics2

Species1

Prevalent1

Infectious diseases1

Pathogenic1

Chronic diseases1

Liver3

Supragingival plaque2

Treatment4

Important1