Study neurogenesis. Medical search. Frequent questions

Facilitation of hippocampal neurogenesis is proposed as a common effect of chronic antidepressant treatment. (thecannabisadvisory.com)
Daily administration of P7C3 to aged rats for 7 days was shown to enhance hippocampal neurogenesis relative to control animals and, after 2 months, treated rats performed significantly better in the Morris water maze test which provides a measure of learning and memory. (drugdiscoveryopinion.com)
Most drugs of abuse examined to date decrease adult hippocampal neurogenesis, but the effects of cannabis (marijuana or cannabinoids) on hippocampal neurogenesis remain unknown. (jci.org)
This study aimed at investigating the potential regulatory capacity of the potent synthetic cannabinoid HU210 on hippocampal neurogenesis and its possible correlation with behavioral change. (jci.org)
X-irradiation of the hippocampus blocked both the neurogenic and behavioral effects of chronic HU210 treatment, suggesting that chronic HU210 treatment produces anxiolytic- and antidepressant-like effects likely via promotion of hippocampal neurogenesis. (jci.org)
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis, doi:10.1038/mp.2014.34, Jeffrey Zigman et al. (medicalnewstoday.com)
In addition, the rats supplemented with BB and SB diets showed increased hippocampal neurogenesis and expression of insulin-like growth factor 1, although the improvements in working memory performance could not solely be explained by these increases. (cambridge.org)
Researchers discover hippocampal neurogenesis occurs daily in adult humans. (neurosciencenews.com)
In male rats, TRAP significantly increased hippocampal neurogenesis, while in females, TRAP increased granule cell layer width. (nature.com)
The most well characterized regulatory steps of adult hippocampal neurogenesis are the rate of progenitor cell proliferation and the survival rate of new DGCs. (jneurosci.org)
So, the effects of MnRN lesion on hippocampal neurogenesis in animals chronically stressed and treated or not with Imipramine (a tricyclic antidepressant) will be investigated too. (fapesp.br)
Acute and long-term effects of adolescence stress exposure on rodent adult hippocampal neurogenesis, cognition, and behaviour. (kcl.ac.uk)
A systematic review was conducted on studies investigating changes in hippocampal neurogenesis and neuroplasticity, hippocampal-dependent cognitive functions, and behaviour, occurring after adolescence stress exposure in mice both acutely (at post-natal days 21-65) and in adulthood. (kcl.ac.uk)
Developing novel tools for measuring hippocampal neurogenesis in live humans, would allow assessing neurogenic changes following stress exposure, investigating relationships with psychiatric symptom onset, and identifying effects of therapeutic interventions. (kcl.ac.uk)

Adult neurogenesis in songbirds is observed in brain circuits that underlie complex specialized behavior, including the song control system and the hippocampus. (wikipedia.org)
Adult neurogenesis in the avian brain occurs in many different pallial regions, including the song nuclei, the hippocampus, and the olfactory regions. (wikipedia.org)
Genetic or pharmacological manipulations of cannabinoid receptors (CB 1 and CB 2 ) or enzymes responsible for endocannabinoid-metabolism have also been shown to control proliferation and neurogenesis in the hippocampus. (thecannabisadvisory.com)
In the hippocampus, some of the beneficial actions of IL6 are attributed to its neurogenesis-inducing properties. (nih.gov)
In this latest study, the researchers found that the hormone can trigger the formation of new neurons, known as neurogenesis, in the hippocampus - the brain region that regulates mood, memory and complex eating behaviors. (medicalnewstoday.com)
In addition, we anticipate PA will ameliorate neuronal loss and promote neurogenesis in the subgranular zone of the dentate gyrus in the hippocampus. (iupui.edu)
Adult-born granule cells (abGCs) project to the CA2 region of the hippocampus, but no previous studies have assigned a behavioral function to this circuit. (researchgate.net)
Many scientists suggested that this continued 'neurogenesis'-which mainly happens in a small region called the hippocampus-might explain how people continue to learn and adapt in new environments long after birth. (discovermagazine.com)
Drew says his future experiments will aim to figure out the psychological role of neurogenesis in the hippocampus. (discovermagazine.com)
Another process that has been described and involves the hippocampus is adult neurogenesis. (fapesp.br)

Adult neurogenesis is the process in which new neurons are born and subsequently integrate into functional brain circuits after birth and into adulthood. (wikipedia.org)
Avian species including songbirds are among vertebrate species that demonstrate particularly robust adult neurogenesis throughout their telencephalon, in contrast with the more limited neurogenic potential that are observed in adult mammals after birth. (wikipedia.org)
The degree of postnatal and adult neurogenesis in songbirds varies between species, shows sexual dimorphism, fluctuates seasonally, and depends on hormone levels, cell death rates, and social environment. (wikipedia.org)
The increased extent of adult neurogenesis in birds compared to other vertebrates, especially in circuits that underlie complex specialized behavior, makes birds an excellent animal model to study this process and its functionality. (wikipedia.org)
Methods used in research to track adult neurogenesis in birds include the use of thymidine analogues and identifying endogenous markers of neurogenesis. (wikipedia.org)
Historically, the discovery of adult neurogenesis in songbirds substantially contributed to establishing the presence of adult neurogenesis and to progressing a line of research tightly associated with many potential clinical applications. (wikipedia.org)
Even though adult neurogenesis is widespread across the telencephalon, all the regions where it is especially high are associated with the learning of new information, suggesting a possible function of adult neurogenesis to be offering an additional avenue of plasticity required during learning. (wikipedia.org)
Although the recruitment of new neurons is widespread in the avian telencephalon, songbirds exhibit particularly robust postnatal and adult neurogenesis in their song control system nuclei. (wikipedia.org)
Adult neurogenesis in the song control system nuclei is shown to be restricted to neurons in Area X, and the neurons of HVC projecting to RA. (wikipedia.org)
A study by researchers at UT Southwestern Medical Center has now shown that Dimebon can increase neurogenesis in adult rodent brains and have identified other, more potent compounds. (drugdiscoveryopinion.com)
Adult neurogenesis is actively studied partly because of the to control endogenous neural stem and progenitor cells for tissues repair. (biongenex.com)
2004 Yet another research using the same targeted apoptosis strategy demonstrated the recruitment of neural progenitors to the region of damage (Brill et a. 2009 Nevertheless since these reviews there were no follow-up studies displaying an endogenous era of glutamatergic projection neurons in the adult neocortex. (biongenex.com)
The hippocampal dentate gyrus in the adult mammalian brain contains neural stem/progenitor cells (NS/PCs) capable of generating new neurons, i.e., neurogenesis. (jci.org)
We show that both embryonic and adult rat hippocampal NS/PCs are immunoreactive for CB1 cannabinoid receptors, indicating that cannabinoids could act on CB1 receptors to regulate neurogenesis. (jci.org)
Chronic, but not acute, HU210 treatment promoted neurogenesis in the hippocampal dentate gyrus of adult rats and exerted anxiolytic- and antidepressant-like effects. (jci.org)
A new study indicates there is a fine line between moderate and binge drinking - a risky behavior that can decrease the making of adult brain cells by as much as 40 percent. (neurosciencenews.com)
Adult neurogenesis in the orex. (uni-marburg.de)
This process is called adult neurogenesis. (uni-marburg.de)
However, our knowledge is still insufficient to exploit adult neurogenesis for controlled brain repair or for stimulation of its physiological function. (uni-marburg.de)
Aim: We aimed to study the possible role of the protein orexin in the regulation of adult neurogenesis in the orexin/ataxin-3 mouse. (uni-marburg.de)
Study design: Adult neurogenesis in the SGZ, SVZ and rostral migratory stream (RMS), where the cells migrate from the SVZ to the olfactory bulb (OB), was studied by immunohistology. (uni-marburg.de)
The phenomenon of neurogenesis in adult animals, which has therapeutic potential in treating neurodegenerative diseases, leads to several questions: What controls the pattern of connections formed by new cells? (pasteur.fr)
Planarians are an attractive model organism for studying stem cell-based regeneration due to their ability to replace all of their tissues from a population of adult stem cells. (ca.gov)
Adult neurogenesis is a complex process whereby neural progenitor cells adopt a neuronal fate, migrate, and mature over several weeks. (jneurosci.org)
Adult neurogenesis is controlled by serotonin and glutamate. (fapesp.br)
We also have a strong interest in basic stem cell biology with a clear focus on neural stem cells and neurogenesis in the adult and aging brain. (lu.se)
Comorbidities and clinical outcomes in adult- and juvenile-onset Huntington's disease: a study of linked Swedish National Registries (2002-2019). (lu.se)

Neurogenesis is the mechanism whereby neurons are developed within the nervous system. (news-medical.net)
Therefore, neurogenesis is used to counteract this problem, by generating new neurons to replace older ones. (news-medical.net)
2006 Significantly the couple of studies which have characterized the identification of newborn neurons in the standard and post-stroke rodent neocortex possess defined them as inhibitory neurons (Dayer et al. (biongenex.com)
2010 Since regenerating just inhibitory neurons may likely verify insufficient for useful recovery two research displaying neurogenesis of neocortical glutamatergic pyramidal neurons after targeted apoptosis had been met with passion (Magavi et al. (biongenex.com)
Medical News Today recently reported on a study from the Icahn School of Medicine at Mount Sinai in New York, NY, which revealed how activating neurons that trigger depression could help treat the disorder . (medicalnewstoday.com)
A decade ago, several independent brain studies found that adults continue to grow new neurons, overturning a long-held belief that the number of cells in a grown-up's brain can only move in one direction: down. (discovermagazine.com)
In the new study , Drew and his colleagues tested this hypothesis by irradiating the small hippocampal region where new neurons form, which is thought to be especially important in spatial learning. (discovermagazine.com)
Three studies reported a reduction in the number of new-born neurons, which however were not associated with changes in cognition or behaviour. (kcl.ac.uk)
Here we establish a midbrain organoid culture system to study the developmental trajectory from pluripotent stem cells to mature dopamine neurons. (lu.se)
Therefore, our aims are to develop cellular models of human neuronal aging and degeneration, to investigate underlying mechanisms responsible for dysfunction in neurons and neural stem cells in the aging and diseased brain and to dissect the regulation of normal neurogenesis. (lu.se)
Studies suggest that a loss of this signaling disrupts the migration and survival of olfactory neurons and GnRH-producing neurons in the developing brain. (medlineplus.gov)
He became convinced that given focus from mapping brain anatomy and the right conditions, immature neurons function to studying brain regeneration. (lu.se)
Hillarp method to study neurons in their entirely new line of research. (lu.se)

This work evaluated the effect of ex situ management on neurogenesis (cell proliferation in the dorsal and medial ventricular zones, neuronal integration in the dorsomedial and medial cortices), ovary cell proliferation, body size (mass and length) and self-righting ability. (frontiersin.org)
Neurogenesis occurs throughout the ventricular zone, but proliferation is especially high in specific locations in the lateral wall of the ventricle. (wikipedia.org)
In patients with ICH, the BDNF concentration in CSF and the neurogenesis-promoting capacity of post-ICH CSF correlated positively with ICH volume.ConclusionBDNF in CSF contributes to post-ICH neurogenesis, including NSC proliferation and differentiation toward neuroblasts in a rat model and patients with ICH. (tmu.edu.tw)
Low-level gestational lead exposure increases retinal progenitor cell proliferation and rod photoreceptor and bipolar cell neurogenesis in mice. (cdc.gov)
Seven studies showed reduced hippocampal cell proliferation, and out of those two reported increased depressive-like behaviours, in adolescent rodents exposed to stress. (kcl.ac.uk)
Among studies who looked at adolescence stress exposure effects into adulthood, seven showed that the negative effects of stress observed during adolescence on either cell proliferation or hippocampal neuroplasticity, cognitive deficits and depressive-like behaviour, had variable impact in adulthood. (kcl.ac.uk)

Although serotoninergic agents such as antidepressants have been shown to increase neurogenesis, the effects of MnRN lesions remain to be elucidated. (fapesp.br)

Controlled stimulation of endogenous neurogenesis might be an elegant way to treat neurodegenerative diseases. (uni-marburg.de)
Our laboratory for the first time combines transplantation of stem cells, stimulation of endogenous neurogenesis and modulation of inflammatory responses in order to develop clinically effective cell replacement therapies for human neurodegenerative diseases. (lu.se)

We used cell labeling with Bromodeoxyuridine (BrdU), immunofluorescence, and real-time PCR to determine the expression of markers of neurogenesis and neurotransmitters. (nih.gov)

Reishi mushrooms have been linked to improved sleep quality and mood, while lion's mane has been associated with reduced anxiety and depression through its effects on neurogenesis. (bacchusgamma.org)
Lion's mane mushrooms have been linked to reduced anxiety and depression through their effects on neurogenesis. (bacchusgamma.org)

Jyo studies chromatin organization during cell fate transitions in neural stem cells and determines how its mis-organization drives aberrant expression of immune modulatory genes and tumorigenesis. (mdanderson.org)

We investigated the role of brain-derived neurotrophic factor (BDNF) in post-ICH neurogenesis in a rodent model and in patients with ICH using cerebrospinal fluid (CSF).MethodsA rat model of ICH was constructed via stereotaxic injection of collagenase into the left striatum. (tmu.edu.tw)
However, these rodent studies usually require forced exposure to ethanol to reveal the brain tissue reduction in vivo and therefore limit the translation to the human condition. (nature.com)

The COVID and Cognition Study is a cross-sectional/longitudinal study aiming to understand cognitive problems in Long COVID. (frontiersin.org)

Regulatory mechanisms in the so-called neurogenic niches have already been shown by in vivo studies for various factors, including numerous neurotransmitters, and behavioral and environmental factors. (uni-marburg.de)

Thus, the present study was carried out to examine these mechanisms in aged animals by administering a control, 2 % SB- or 2 % BB-supplemented diet to aged Fischer 344 rats for 8 weeks to ascertain their effectiveness in reversing age-related deficits in behavioural and neuronal function. (cambridge.org)

Wild-type (WT) and IL6 knockout (KO) mice were employed to study the capacity of IL6 to induce neurogenesis. (nih.gov)
IL6 induces neurogenesis-related gene expression in the hypothalamus and in neuroprogenitor cells, both from WT as well as from KO mice. (nih.gov)
IL6 induces neurogenesis-related gene expression in the hypothalamus of WT mice. (nih.gov)
In 2015, researchers behind a study in mice concluded that apigenin and apigenin-rich diets reduced the expression of certain inflammatory proteins. (medicalnewstoday.com)
He employs biochemical techniques for in vitro studies and uses genetically engineered mice and xenograft models to study tumor development. (mdanderson.org)
This study demonstrated that overexpression of miR-203 suppressed the angiogenesis in mice with pathological retinal neovascularization disease via the inactivation of GSK-3 β / β -catenin pathway by inhibiting SNAI2. (hindawi.com)
Thus, additional, easy-to-use, and widely available monoclonal antibodies would be advantageous to study regeneration in planarians.ResultsWe have created seven monoclonal antibodies by inoculating mice with formaldehyde-fixed cells isolated from dissociated 3-day regeneration blastemas. (ca.gov)
Mice raised in the fun cages also 'had a big boost in neurogenesis' as adults, according to Columbia neuroscientist Michael Drew, which suggested that neurogenesis may be 'the way the brain adapts to increased complexity in its environment. (discovermagazine.com)

There are also epigenetic factors which are utilized in the control of neurogenesis, as well as cytokines, morphogens, neurotransmitters and growth factors. (news-medical.net)

Recently, a growing number of studies are focusing on mesenchymal stem cell-based therapies for neurodegenerative disorders. (hindawi.com)
Using novel stem cell, reprogramming and genome editing technologies we are studying how genetic pathways involved in aging and neurodegenerative disease affect formation and function of neural cells. (lu.se)

STUDY: Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link? (thecannabisadvisory.com)
In the present paper we reviewed the studies that have investigated the potential contribution of cannabinoids and neurogenesisto antidepressant effects. (thecannabisadvisory.com)

In a 2008 study led by Dr. Zigman, the research team found that ghrelin had natural antidepressant properties that are prominent when its levels increase due to prolonged psychological stress or caloric restriction. (medicalnewstoday.com)
The team found that the P7C3 compounds enhanced the neurogenesis properties of ghrelin, leading to a strong antidepressant effect. (medicalnewstoday.com)
The team says that in future studies, they want to apply their findings to other forms of depression, as well as create clinical trials to determine whether P7C3 compounds have antidepressant effects for individuals with major depressive disorder. (medicalnewstoday.com)

In a 2009 study , researchers gave rats apigenin and found that it stimulated nerve cell generation and improved the ability to learn and remember. (medicalnewstoday.com)
In a new study, published in Nature Communications, researchers have uncovered the molecular players involved and how the timing is controlled. (illinois.edu)
A study of the salamander brain has led researchers at Karolinska Institutet to discover a hitherto unknown function of the. (neurosciencenews.com)
Researchers tend to focus much of their attention on social support, but we found that a low sense of belonging was a much stronger predictor of depression than social support," said Reg A. Williams, associate professor of nursing and co-author of the study that appears in the July/August issue of Nursing Research. (sciencedaily.com)

Sixteen studies showed acutely reduced hippocampal neuroplasticity, including pre- and post-synaptic plasticity markers, dendritic spine length and density, and long-term potentiation after stress exposure. (kcl.ac.uk)

Apigenin may also stimulate neurogenesis, the growth and development of nerve cells. (medicalnewstoday.com)

However, despite having the promising outcome of preclinical studies, the clinical application of stem cell therapy remained elusive due to little or no progress in clinical trials. (hindawi.com)
The objective of this study was to provide a generalized critique for the role of mesenchymal stem cell therapy in ischemic stroke injury, its underlying mechanisms, and constraints on its preclinical and clinical applications. (hindawi.com)
The recent decade has seen encouraging outcomes of mesenchymal stem cell therapy that holds promise to alleviate the burden of neurological disorders Moreover, initial study data of preclinical trials have also indicated the effectiveness, tolerance, and safety of MSC-based therapy [ 10 ]. (hindawi.com)
We aim to provide the basis for establishing a future study to promote the clinical translation of stem cell therapy in ischemic brain diseases. (hindawi.com)
The objective of this study is to isolate and characterize stem cells from the pulp of permanent third molars and analyze the cells obtained in terms of their morphology and chondrogenic, osteogenic and adipogenic cell differentiation. (bvsalud.org)

Once the nervous system is fully formed, neurogenesis only occurs due to stimuli. (news-medical.net)

Since neurotrophic factors are the primary architects of neurogenesis, synaptic plasticity, learning, and memory, the findings from preclinical and clinical studies that assess changes in neurogenesis and neurotrophic factors and their relationship to cognitive performance in schizophrenia, and how these mechanisms might be impacted by APD treatment, may provide valuable clues in developing therapies to combat cognitive deficit in schizophrenia. (benthamscience.com)

The first paper from the study explored the characteristics of our sample of 181 individuals who had experienced the COVID-19 infection, and 185 who had not, and the factors that predicted ongoing symptoms and self-reported cognitive deficits. (frontiersin.org)
We will also investigate if neurogenesis is related to the cognitive deficits observed in depressive patients, using another two animal models of depression. (fapesp.br)

[ 3 ] Newer studies have implicated lithium in neurogenesis, as well as neural regeneration. (medscape.com)
Novel monoclonal antibodies to study tissue regeneration in planarians. (ca.gov)
In 2011, in studying brain regeneration, because he received the Robert A. Pritzker Prize they thought it was hopeless. (lu.se)

Alterations have also been attributed to several diseases, such as depression and epilepsy, highlighting the importance of a highly controlled balance between neurogenesis and neurodegeneration. (news-medical.net)
ANN ARBOR---A psychological sense of belonging is a greater predictor of major depression than other factors commonly associated with depression, such as social support, conflict and loneliness, according to a new University of Michigan School of Nursing study. (sciencedaily.com)
The study is based on the results of analysis of 31 clients diagnosed with and in treatment for major depression and 379 community college students. (sciencedaily.com)
Williams and Bonnie M. Hagerty, an associate professor of nursing and senior author of the study, analyzed the impact of a psychological sense of belonging, social support, conflict and loneliness on depression. (sciencedaily.com)

Neurogenesis observed in the song system brain areas is shown to be associated with the learning of new songs. (wikipedia.org)
Dr. Fulton Crews, John Andrews Distinguished Professor, Professor of Pharmacology and Psychiatry, and Director of UNC's Bowles Center for Alcohol Studies, has advanced the understanding of the role of innate immune signaling in the brain including the discovery that ethanol induction of innate immune signals contributes to the neurobiology of addiction. (unc.edu)
Crews' group first extended previous studies suggesting that alcohol activated a key transcription factor, NF-kB, in brain. (unc.edu)
Previous studies have shown that P7C3 compounds have neuroprotective abilities in patients with Parkinson's disease , amyotrophic lateral sclerosis (ALS) and traumatic brain injury . (medicalnewstoday.com)
Nonhuman primate models offer several advantages for the study of ethanol-induced brain damage. (nature.com)
A new study argues that prolonged chemotherapy decreases the development of new brain cells, and disrupts ongoing brain rhythms in the part of the brain responsible for making new memories. (neurosciencenews.com)
Dong studies the role of arginine methylation in the development of pediatric brain tumors. (mdanderson.org)
Three-dimensional brain organoids have emerged as a valuable model system for studies of human brain development and pathology. (lu.se)
However, despite significant advancements in the field, the use of brain organoids can be limited by issues of reproducibility and incomplete maturation which was also observed in this study. (lu.se)

How is the stability of memory and of information processing maintained when cells and synapses are constantly being lost and new ones produced?To answer these questions we intend to investigate neurogenesis in the mammalian olfactory bulb, using a combination of computational modeling and electrophysiology. (pasteur.fr)
Using this model we will investigate odor information processing, learning and memory in the olfactory bulb, and how these are affected by neurogenesis. (pasteur.fr)

Most animal studies published to date, however, have employed exposure paradigms that do not capture the complexity or spatiotemporal dynamics of real-world TRAP exposures. (nature.com)

The molecular toolkit for planarian studies currently includes the ability to study gene function using RNA interference (RNAi) and observe gene expression via in situ hybridizations. (ca.gov)
We are currently performing clinical study to characterize the phenotype and gene expression profile of peripheral blood monocytes in patients with stroke. (lu.se)

One of the compounds, P7C3, was selected for further study on the basis of favourable ADME predictions. (drugdiscoveryopinion.com)

Although this idea can only be rigorously tested after identification of the molecular target(s), the study raises the hope that more potent analogues of Dimebon with improved clinical efficacy could be identified and also provides appropriate assays. (drugdiscoveryopinion.com)
A major focus of our research involves the study of developmental signals required for normal cerebellar development as a means to understand the molecular basis and pathophysiology of medulloblastoma. (mdanderson.org)
We show that silk organoids reproduce key molecular aspects of dopamine neurogenesis and reduce inter-organoid variability in terms of cell type composition and dopamine neuron formation. (lu.se)

Laboratory studies aim to rule out potential causes or, more often, triggers for seizures. (medscape.com)
Attendance is compulsory for all group tuition, laboratory sessions and study visits. (lu.se)

In a series of studies, Crews first found an important role for chemokines, cytokines, proteases and oxidase enzymes that contribute to alcohol-induced neurodegeneration. (unc.edu)

First, the brains of old-world monkeys, such as the rhesus macaque ( Macaca mulatta ) species studied here, are gyroencephalic and, like humans, have a large fraction of intracranial space occupied by white matter. (nature.com)

Neurogenesis is tightly controlled, to ensure correct levels of activation. (news-medical.net)

Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. (medicalnewstoday.com)
The course also includes study visits to laboratories where modern techniques within neurobiology research are demonstrated. (lu.se)
This study was approved by the Human and Animal Research Ethics Committee at ULBRA (CEP-ULBRA 2009-361H) and all participants signed a free and informed consent form. (bvsalud.org)

Epifluorescent, light and confocal microscopy studies, and Western blots demonstrated that late-born rod photoreceptors and rod and cone bipolar cells, but not Müller glial cells, increased in a nonmonotonic manner by 16-30% in PN60 GLE offspring. (cdc.gov)
BrdU-birthdating and confocal studies confirmed the selective rod and bipolar cell increases and showed that the patterns of neurogenesis and gliogenesis were unaltered by GLE. (cdc.gov)
However, a study by Hsu et al indicated that in patients with euthymic bipolar disorder, lithium serum levels of 0.4-0.8 mmol/L significantly inhibit the recurrence of major mood episodes, although this effect was found only in patients aged 40-60 years. (medscape.com)
Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia. (nih.gov)

The study "A comprehensive temporal patterning network in Drosophila medulla neuroblasts revealed by single-cell RNA sequencing" was published in Nature Communications. (illinois.edu)
I study the ability for implanted neuroblasts therapies for the disease. (lu.se)

Why is neurogenesis required in adults? (news-medical.net)

We have postulated that these effects may be the result of a number of positive benefits of the berry polyphenols, including decreased stress signalling, increased neurogenesis, and increased signals involved in learning and memory. (cambridge.org)

The study is published in the journal Cell . (drugdiscoveryopinion.com)

A pilot reverse virtual screening study suggests toxic exposures caused long-term epigenetic changes in Gulf War Illness. (cdc.gov)

According to previously established studies [ 8 ], the ischemic avalanche followed by a stroke is comprised of three phases, i.e., (i) acute phase, (ii) the subacute phase, and (iii) the chronic phase (Figure 1 ). (hindawi.com)

This balance can be enhanced by many different factors, including increased neurogenesis due to more physical activity, engaging environments, and education. (news-medical.net)

Increasing evidence suggests that the immune system plays a direct role in AD pathogenesis, and several studies show that APOE genotype alter inflammatory pathways. (iupui.edu)
In this study, we aimed to analyze the enzymes and components of the purinergic system involved in the inflammatory process triggered by the P2X7R. (bvsalud.org)

Neurogenesis in songbirds was first identified and has been most well studied in the song control system. (wikipedia.org)

Anatomy42

Organisms11

Diseases6

Chemicals and Drugs40

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Psychiatry and Psychology11

Phenomena and Processes32

Disciplines and Occupations1

Anthropology, Education, Sociology and Social Phenomena3

Information Science1

Health Care2

Hippocampal neurogenesis14

Hippocampus10

Adult27

Neurons13

Proliferation6

Increase neurogenesis1

Endogenous2

Markers of neurogenesis1

Effects on Neurogenesis2

Neural stem1

Rodent2

Cognition1

Neurogenic1

Neuronal1

Mice8

Neurotransmitters1

Neurodegenerative2

Cannabinoids2

Antidepressant3

Researchers4

Neuroplasticity1

Stimulate1

Stem5

Occurs1

Preclinical1

Deficits2

Regeneration3

Depression4

Brain9

Olfactory bulb2

Exposure1

Gene expression2

P7C31

Molecular3

Laboratory2

Cytokines1

Humans1

Tightly1

Research3

Bipolar4

Neuroblasts2

Adults1

Signals1

Cell1

Epigenetic1

Acute1

Physical activity1

Inflammatory2

Control1