• AIDS
  • 1 The joint United Nations Programme on HIV/AIDS (UNAIDS) estimated that 2.3 million new infections and 1.6 million AIDS deaths occurred in 2012 and almost 35.3 million adults and children worldwide are living with HIV or AIDS. (scielo.org.za)
  • Sub-Saharan Africa remains the region worst affected by HIV and AIDS. (scielo.org.za)
  • In the vast majority of those infected with HIV virus who are untreated, there is deterioration in immune health over a period of months or years inevitably leading to full-blown AIDS and demise. (clinicaltrials.gov)
  • The investigators' study hypothesis is that effectiveness of a very low dose of an FDA-approved medication, naltrexone hydrochloride, (Low-Dose Naltrexone, or LDN) will compare favorably to ARV's to prevent progression of HIV+ toward immune deterioration and full-blown AIDS. (clinicaltrials.gov)
  • The term serostatus is commonly used in HIV/AIDS prevention efforts. (wikipedia.org)
  • In recent years, social advocacy has emphasized the importance of learning one's HIV/AIDS serostatus in an effort to curtail the spread of the disease. (wikipedia.org)
  • Mozambique is a country particularly hard-hit by the HIV/AIDS epidemic. (wikipedia.org)
  • In order to reduce the prevalence of HIV/AIDS within the country, Mozambique has partnered with numerous global organizations to provide its citizens with augmented access to antiretroviral therapy and prevention techniques, such as condom use. (wikipedia.org)
  • A surge toward the treatment and prevention of HIV/AIDS in women and children has additionally aided in Mozambique's aim to fulfill its Millennium Development Goals (MDGs). (wikipedia.org)
  • The first governmental response to the HIV/AIDS epidemic occurred in 1988 with the establishment of four sentinel surveys in Maputo, Beira, Chimoio, and Tete to keep track of HIV prevalence within the country. (wikipedia.org)
  • Before the nationwide introduction of ART, only cotrimoxazole prophylaxis and drugs to diminish the effects of opportunistic infections were administered to people living with HIV/AIDS (PLWHA). (wikipedia.org)
  • Yet, since the end of the civil war in 1992, rural areas of Mozambique continue to face repercussions of the HIV/AIDS epidemic, prominently due to the inability of the nation to quickly rehabilitate as a result of inadequate funds allocated towards addressing both educational and healthcare system infrastructural repairs. (wikipedia.org)
  • What's more, women and children are more likely than men to experience a general lack of awareness of the cause, transmission, and ways of prevention of HIV/AIDS. (wikipedia.org)
  • At the 2010 International AIDS conference presenters talked about the need for community healthcare providers to understand that if their patients have been in an HIV vaccine trial then their patients are likely to give a false positive HIV test result. (wikipedia.org)
  • infections
  • Untreated coinfections, such as malaria, tuberculosis, and sexually transmitted infections (STIs) can also propagate the spread of HIV within a population through the weakening of the host's immune system. (wikipedia.org)
  • These include HIV, Hepatitis B, Hepatitis C, Treponema pallidum (syphilis) and, where relevant, other infections that pose a risk to the safety of the blood supply, such as Trypanosoma cruzi (Chagas disease) and Plasmodium species (malaria). (wikipedia.org)
  • Also doctors do not routinely test people for recent infections with most diseases as they do for HIV. (wikipedia.org)
  • Epidemic
  • Several campaigns and organizations have been initiated since 1986 in order to combat the HIV epidemic in various ways and by reaching various sectors of Mozambican society. (wikipedia.org)
  • 2001
  • By the year 2001, HIV had infected more than one million people, 53,000 of which were children under 18 years of age and 570,000 of which were women. (wikipedia.org)
  • vaccine
  • In 1987 in America the first HIV vaccine was tested. (wikipedia.org)
  • HIV vaccines have been tested continually worldwide since then, but thus far, no one has developed any vaccine which reduces a person's risk of contracting HIV if exposed to that virus. (wikipedia.org)
  • citation needed] A person who is HIV negative, and has received an HIV vaccine, and who then tests as positive in an HIV test is said to be positive because of VISP. (wikipedia.org)
  • HIV vaccine research happens worldwide to ensure that any vaccine which researchers develop could be used for people worldwide. (wikipedia.org)
  • People who participate in vaccine trials which test HIV vaccines may exhibit VISP for years or for the rest of their lives. (wikipedia.org)
  • antibodies
  • Many HIV tests work not by checking a person's blood for HIV, but rather by determining whether the body's own antibodies against HIV are present in the blood. (wikipedia.org)
  • citation needed] Most HIV vaccines are designed with the intent to promote the body's own production of antibodies which would combat HIV. (wikipedia.org)
  • populations
  • Study of seronegative patient populations has led to the identification of additional autoantibodies that could potentially help with diagnosis. (wikipedia.org)
  • however
  • However, by 2009 numerous studies had failed to find evidence of XMRV in prostate cancer. (wikipedia.org)
  • However, as study sizes increased and D serotypes were described in more detail, the association of these loci moved from the MHC class I loci to the MHC class II loci. (wikipedia.org)
  • dose
  • PURPOSE: This phase I/II trial is studying the side effects and best dose of everolimus when given together with temozolomide and radiation therapy and to see how well it works in treating patients with newly diagnosed glioblastoma multiforme. (clinicaltrials.gov)
  • To determine a dose suitable for Phase II or III evaluation in HIV-infected patients. (clinicaltrials.gov)
  • Stable dose of antiretroviral (must be stable for at least 1 month prior to study entry). (clinicaltrials.gov)
  • Each person in this arm 1 of the study had never received any ARV drugs and in this study received only one Low-Dose Naltrexone 3mg capsule nightly for 9 months (no placebo). (clinicaltrials.gov)
  • The LDN (low-dose naltrexone) vs ARV (anti-retroviral drugs) Effectiveness Study in Mali sponsored by The Ojai Foundation in California-USA is a clinical research study endorsed and approved by the Malian Government. (clinicaltrials.gov)
  • Patients receive an intravenous (IV) dose of AZT on the first day of the study, followed by an oral dose 24 hours later on the second day of the study. (clinicaltrials.gov)
  • people
  • 2 SA has the highest number of people living with HIV. (scielo.org.za)
  • 10 A team of researchers in Denmark found that HIV-positive people had between a two- and fourfold elevated risk for developing schizophrenia compared to HIV-negative people and they also had a four- to sevenfold elevated risk for developing psychosis. (scielo.org.za)
  • researchers
  • Researchers from Africa, Asia, North America, and South America have said that getting local government and media support of the research is essential in addition to creating facilities for distinguishing between HIV positive individuals and individuals exhibiting VISP. (wikipedia.org)
  • negative
  • When an HIV-negative person exhibits VISP and gets an HIV-positive result from a test then that person may have difficulty donating blood or negotiating for a life insurance policy. (wikipedia.org)
  • medical
  • HIV-infected patients were also less likely to be diagnosed as having schizophrenia (33.0%), had higher rates of medical (73.0%) and psychiatric (21.0%) comorbid disorders and were less likely to report lifetime nicotine and cannabis use ( p = 0.047 and p = 0.011). (scielo.org.za)
  • women
  • This study is designed to show if CarraguardĀ® can protect women against HIV if it is used before sex, and is safe for long-term use. (clinicaltrials.gov)
  • found
  • Another German study found no XMRV association with non-familial (sporadic) prostate cancer, and no XMRV link was found in Irish prostate cancer patients with the R462Q mutation. (wikipedia.org)
  • A recent study of DR3-DQ2/DR4-DQ8 phenotype found that A1-cw7-B8 was actually lower than expected relative to other A-B types, indicating that risk associated genes are located between B8 and DR3. (wikipedia.org)
  • The study found that valaciclovir significantly reduced shedding during subclinical days compared to placebo, showing a 71% reduction. (wikipedia.org)
  • Time
  • Immediately following this fight, in 1977, a 15-year civil war broke out, an event that concluded in 1992, around the same time that HIV first swept through the southern regions of Africa. (wikipedia.org)
  • transmission
  • The purposes of this study are to determine whether CarraguardĀ® Gel can prevent the transmission of HIV when used during vaginal intercourse, and to confirm that the gel is safe for vaginal use. (clinicaltrials.gov)
  • Studies on discordant partners (one infected with HSV-2, one not) show that the transmission rate is approximately 5 per 10,000 sexual contacts. (wikipedia.org)