Study cell communication. Medical search. Frequent questions

It is so well regulated that it allows cells to encode information," José Feijó, a professor of cell biology and molecular genetics at the University of Maryland, said in a news release. (upi.com)
The findings solve a fundamental problem afflicting systems biology: measuring how cells communicate with each other," said Yashir Suhail, a postdoctoral fellow, in the Dental School's Department of Biomedical Engineering. (zmescience.com)
Chemical genetics can serve as a unifying study between chemistry and biology. (wikipedia.org)
Cell Biochemistry & Function publishes original research articles and reviews on the mechanisms whereby molecular and biochemical processes control cellular activity with a particular emphasis on the integration of molecular and cell biology, biochemistry and physiology in the regulation of tissue function in health and disease . (wiley.com)
The primary remit of the journal is on mammalian biology both in vivo and in vitro but studies on the biochemistry and function of cells in situ are especially encouraged . (wiley.com)
Observational and pathological studies will be considered providing they include a rational discussion of the possible molecular and biochemical mechanisms underlying the results and their immediate impact on our understanding of mammalian biology . (wiley.com)
It's one thing to find that this intricate physical networkexists but quite astonishing to learn that immune system cells areusing it to relay molecular signals to one another," said Dr. Watkins,professor and vice chair, department of cell biology and physiology,and director of the Center for Biologic Imaging, University ofPittsburgh School of Medicine. (sciencedaily.com)
Systems Biology Approach to Study Heterogeneity and Cell Communication Networks in the Tumour Microenvironment. (routledge.com)
It is great to have a strong background in biology (BIO143 & 144) and laboratory technique (CHM108 & 110, BIO143L &144L), in addition to either cell and molecular biology (BIO231W) or neuroscience (BIO209). (chatham.edu)
With her background in cell biology and biochemistry, Marleen van Stevendaal wanted to investigate whether it was possible for these synthetic cells to communicate with organic cells. (tue.nl)
A new study illuminates the biology that guides behavior across different stages of life in worms, and suggests how variations in specific neuromodulators in the developing nervous system may lead to occasional variations. (rockefeller.edu)
The team of specialists in immunology, genomics, proteomics and airway biology then measured all the proteins produced in infected cell cultures. (ncl.ac.uk)
Researchers at the Center for Molecular Biology of Heidelberg University, the German Cancer Research Center and the Heidelberg Institute for Theoretical Studies collaborated on the project, along with other scientists from Germany, the USA and Switzerland. (uni-heidelberg.de)
If such aggregates form, they can damage the cells and even cause the cells to die, which we see in neurodegenerative diseases such as Alzheimer's and Parkinson's, and even in ageing processes," explains Prof. Dr. Bernd Bukau, Director of the Center for Molecular Biology of Heidelberg University (ZMBH), who is also a researcher at the German Cancer Research Center (DKFZ). (uni-heidelberg.de)
To determine whether this biology is conserved in humans, we characterized the colonic Î³Î´ T cell compartment, identifying a diverse repertoire that includes a phenotypically distinct subset coexpressing T cell receptor VÎ³4 and the epithelium-binding integrin CD103. (bvsalud.org)

May 3 (UPI) -- Researchers have identified a new type of communication between plant cells. (upi.com)
In a new study, published this week in the journal Science , researchers present a new model to describe how glutamate receptor-like proteins, or GLR proteins, function in plant cells. (upi.com)
Scientists believe their new plant communication model could help researchers study crop disease and better understand how plants respond to climate change and other stressors. (upi.com)
During one experiment, the researchers zoomed in on stem cells from bone marrow that can be used to treat a myocardial infarction, also known as a heart attack. (zmescience.com)
In the lab, the researchers used this information to make a protein cocktail that could one day be used to treat an injury without the use of stem cells. (zmescience.com)
In this new study, researchers investigated the role of signaling between colon cancer cells and normal cells and how chemotherapy drugs and BCM-95 Curcumin affect that communication. (naturalpractitionermag.com)
Additionally, researchers examined the impact of the treatments on markers of cancer stem cells. (naturalpractitionermag.com)
In this way the researchers were able to relate cellular dysfunction to changes in cell morphology. (eurekalert.org)
Researchers Discover Urea Buildup in Brain Cells is Major Cause of. (nutritionreview.org)
While gap junctions -- interconnecting molecular bridges thatconjoin tightly packed cells -- are known to generate calcium signalsand transport other molecules between cells, the researchers say thetunneling nanotubules are something quite different. (sciencedaily.com)
To better understand these phenomena, researchers are trying to create living cells from the very smallest building blocks. (tue.nl)
The synthetic cells we use are constructed from materials that do not occur at all in nature, although other researchers make synthetic cells solely with natural building blocks such as DNA," adds van Stevendaal. (tue.nl)
So, researchers from University College London (UCL) created a custom multivariate-barcoded mass cytometry method to analyze single-cell PTM signaling in organoids. (scienceboard.net)
By understanding how minitumors function at the single-cell level, this new technology will enable researchers to identify new ways to treat an individual's cancer," said Tape. (scienceboard.net)
In this new study, researchers conducted blood tests on 1,000 participants from three separate studies involving cognitively healthy older adults with and without amyloid buildup. (medicalnewstoday.com)
Cellular repair systems can dissolve aggregated proteins and now Heidelberg researchers have successfully decoded the fundamental mechanism that is key to dissolving these protein aggregates in human cells. (uni-heidelberg.de)
The researchers report that very little was known about how our natural defences reverse the process of protein aggregation so effectively in young healthy cells. (uni-heidelberg.de)
The Heidelberg researchers also studied the co-chaperones that regulate Hsp70 activity in the protein complex. (uni-heidelberg.de)
To see if glial cells contribute to schizophrenia , the researchers first took samples of skin cells from people who developed schizophrenia in childhood, before age 13. (livescience.com)
The researchers then manipulated the iPSCs so they turned into glial progenitor cells, or the cells in the body that give rise to glial cells. (livescience.com)
The researchers transplanted the glial progenitor cells into the brains of young mice. (livescience.com)
for example, the cells did not give rise to enough myelin-producing cells, so transmission between neurons was impaired, the researchers said. (livescience.com)
The mice with these faulty cells also exhibited anti-social and anxious behaviors, similar to the behaviors seen in people with schizophrenia, the researchers said. (livescience.com)
In response to this evidence, public health officials and researchers recommend communication messages and interventions to educate the public about maintaining cognitive health (2,6-9). (cdc.gov)

The communication mechanisms deployed by plants aren't a more primitive version of animal neurons, however, as they boast their own unique communication systems. (upi.com)
Inside the brain, the nerve cells, which are also called "neurons," are woven into a network in which they relay signals to one another. (eurekalert.org)
At first, they examined the electrical activities of individual neurons as well as those of larger cell groups. (eurekalert.org)
The research proves cells other than neurons are capable of long-distance communication and reveals a hereto-unknown mechanism cells use for exchanging information. (sciencedaily.com)
The research not only proves cells other than neurons arecapable of long-distance communication, but it reveals a hereto-unknownmechanism cells use for exchanging information. (sciencedaily.com)
His exquisite renderings of complex and diverse neurons showed that instead of being a tangled nest of fused fibers, the nervous system is an intricately connected network of discrete nerve cells, a claim called the neuron doctrine. (sciencenews.org)
Alongside other glial cells, the brain's resident immune cells, astrocytes support neurons by providing them with nutrients, oxygen, and protection against pathogens. (medicalnewstoday.com)
Previously the role of astrocytes in neuronal communication had been overlooked since glial cells do not conduct electricity like neurons. (medicalnewstoday.com)
The study focused on glial cells , which provide support for the neurons that do the "signaling" within the brain. (livescience.com)
For instance, glial cells help organize the connections among neurons and produce myelin, which acts as insulation around the brain's nerve fibers. (livescience.com)
This resulted in "chimeric" mice, meaning they had regular mouse neurons but human glial progenitor cells. (livescience.com)
In addition, a type of glial cells called astrocytes did not mature properly and weren't able to fully support the neurons. (livescience.com)
The adult brain is made up of more than 10 billion nerve cells called neurons. (msdmanuals.com)

Plants don't have a central nervous system, but to communicate, their cells rely on proteins that look a lot like the glutamate receptors used by the neuronal cells of animals. (upi.com)
Their observations suggest "cornichon" proteins help ferry GLRs from place to place and regulate the protein's activity in each cell. (upi.com)
With the help of cornichon proteins, GLRs work to control the concentration and flow of calcium ions in plant cells. (upi.com)
While humans use words and language to communicate, cells send and receive messages or instructions by secreting proteins. (zmescience.com)
The team recorded proteins that were secreted by these stem cells, as well as how these secretions changed with time. (zmescience.com)
While stem cells are flexible enough to change their function and behavior depending on the site of injury, it is possible to copy a particular stem cell behavior and create a cell-less therapy that only uses proteins. (zmescience.com)
In this study, treatment with curcumin impeded cancer growth and proliferation by inhibiting signaling proteins and blocking tumor cell promotion. (naturalpractitionermag.com)
Rspo proteins are secreted and can stabilize the effects of Wnt ligands by preventing ubiquitination and turnover of the Wnt receptor frizzled 9 , thereby dictating the size of the Lgr5 + stem cell pool by regulating self-renewal of Lgr5 + cells 10 . (nature.com)
Chemical genetics is the investigation of the function of proteins and signal transduction pathways in cells by the screening of chemical libraries of small molecules. (wikipedia.org)
Cells communicate in different ways, but one of these is through proteins. (tue.nl)
This communication system is designed to transfer proteins between synthetic cells. (tue.nl)
In our research, the system has already worked in the presence of living cells, using proteins that also have the potential to start passing signals to living cells. (tue.nl)
Chemokines are the proteins that cells use to guide one another. (tue.nl)
Dr. Liu's research group primarily employs X-ray crystallography in combination with mechanistic, biological and computational methods to study proteins involved in bacterial infections and other human diseases. (luc.edu)
One insight is the identification of tumor antigens (small proteins recognized as "foreign" by the immune system) that stimulate the T-cells of the immune system. (oncolink.org)
Reactive astrocytes, a type of brain cell, could help scientists understand why some people with healthy cognition and amyloid-β deposits in their brains do not develop other signs of Alzheimer's, such as tangled tau proteins. (medicalnewstoday.com)
Proteins in all cells - from bacteria to human - are folded in their native state. (uni-heidelberg.de)
Dissolving protein aggregates is a critical step in recycling defective proteins and providing protection against stress-induced cell damage. (uni-heidelberg.de)

A recently published cellular study on colorectal cancer showed that high-absorption BCM-95 Curcumin is able to reduce the spread of cancer cells and potentially increase the effectiveness of chemotherapy in the treatment of advanced colon cancer. (naturalpractitionermag.com)
Signaling (cellular communication) between cancer cells and normal cells is a key factor in how cancer progresses, and this "signaling" increases the survival, proliferation, and malignant behavior of tumor cells and their ability to resist chemotherapy drugs, according to BCM-95. (naturalpractitionermag.com)
Thus, we find that endogenous Rspo3 signaling is a critical determinant of cellular fate within the crypt and stimulates rapid recruitment of differentiated cells for epithelial wound healing and crypt regeneration through induction of Wnt signaling. (nature.com)
Although cellular and in vivo studies have provided considerable insight into the downstream consequences of Notch signalling, relatively little is known about the molecular basis of the receptor/ligand interaction and initial stages of activation. (nih.gov)
Chemical genomics small molecule probes to study cellular function. (wikipedia.org)
Hence, we assume that the dysfunctions in cellular communication that manifest in other brain diseases are also resulting from structural changes. (eurekalert.org)
From his drawings, Cajal correctly guessed that nerve impulses travel directionally along cellular tendrils to send messages to adjacent cells. (sciencenews.org)
The survey featured questions on sociodemographic characteristics, occupational history, cell phone technology ownership, and cellular text/email services capabilities. (cdc.gov)
As a result, EV fusion leads to the modulation of cellular functions and has an impact on both physiological and pathological processes in the recipient cell. (lu.se)
This study explores the impact of EV fusion on cellular responses to inflammatory signaling. (lu.se)
Studies on cellular phenotype and communication. (lu.se)
The term Langerhans cell histiocytosis is generally preferred to the older term, histiocytosis X. This newer name emphasizes the histogenesis of the condition by specifying the type of lesional cell and removes the connotation of the unknown ("X") because its cellular basis has now been clarified. (medscape.com)
Specifically, a variety of other cellular populations have been identified that possess phenotypic characteristics similar to Langerhans cells, including expression of CD207 and Birbeck granules. (medscape.com)
Therefore, in addition to epidermal Langerhans cells, other potential cellular origins for LCH include dermal langerin + dendritic cells, lymphoid tissue-resident langerin + dendritic cells, and monocytes that can be induced by local environmental stimuli to acquire a Langerhans cell phenotype. (medscape.com)

Kshitiz and colleagues employed microfluidics and computer modeling to reveal the precise wording and structure of intercellular communication. (zmescience.com)
Interestingly, if not for a minor mishap while carrying out anexperiment, the authors might not have discovered the existence ofthese physical structures and conducted the studies that revealed theirrole in intercellular communication. (sciencedaily.com)
This is clearly a third form of intercellular communication,distinct from gap junctions and synapses used by nerve cells. (sciencedaily.com)
Extracellular vesicles (EVs) play a crucial role in intercellular communication by transferring bioactive molecules from donor to recipient cells. (lu.se)

Such an approach could avoid some of the complications associated with stem cell transplants. (zmescience.com)
Cancer stem cells (CSCs) play an important role during metastasis, but the dynamic behavior and induction mechanisms of CSCs are not well understood. (nature.com)
Mechanistically, stemness is induced in non-stem cancer cells upon their direct contact with macrophages via Notch-Jagged signaling. (nature.com)
In breast cancers from patients, the density of TMEM doorways correlates with the proportion of cancer cells expressing stem cell markers, indicating that in human breast cancer TMEM doorways are not only cancer cell intravasation portals but also CSC programming sites. (nature.com)
At the apex of the hierarchy are the cancer stem cells (CSCs). (nature.com)
In mammary gland development, Notch-dependent heterotypic signaling between resident tissue macrophages and mammary stem cells supports survival and function of the normal mammary stem cell 20 . (nature.com)
Cancer stem cells are responsible for developing resistance to chemotherapy and the recurrence of cancer after treatment. (naturalpractitionermag.com)
One finding of this study was that treatment with 5-FU actually promoted the growth of cancer stem cells, which may account for the high incidence of recurrence in colon cancer. (naturalpractitionermag.com)
Cancer stem cells exist in very small numbers in a tumor and can hide from chemotherapy. (naturalpractitionermag.com)
I believe cancer stem cells are the main reason why we can't stop cancer. (naturalpractitionermag.com)
According to the company, the addition of curcumin reduced the amount of 5‑FU needed to inhibit cancer cell growth substantially and sensitized the cancer stem cells to chemotherapy treatment. (naturalpractitionermag.com)
The colonic epithelial turnover is driven by crypt-base stem cells that express the R-spondin receptor Lgr5. (nature.com)
Signals that regulate epithelial regeneration upon stem cell injury are largely unknown. (nature.com)
The majority of epithelial cells are therefore short-lived, in contrast to a limited number of long-lived stem cells in the base of the crypts. (nature.com)
Lgr5 is a well-established marker of these basal stem cells in the gastrointestinal tract 1 and lineage tracing experiments have demonstrated that Lgr5 + cells give rise to clonal cell populations establishing entire colonic crypts 2 . (nature.com)
While Lgr5 + cells are long-lived and act as stem cells during homeostatic conditions, experimental models have demonstrated that Lgr5 + stem cells per se are not essential for maintaining epithelial integrity 3 . (nature.com)
Expression of Lgr5 is controlled by Wnt signaling, which plays a critical role for stem cell turnover in the gastrointestinal tract 2 . (nature.com)
We have shown that in the stomach, stem cell homeostasis is regulated by Wnt and Rspo secreted by stromal myofibroblasts 11 . (nature.com)
Tracing Stem Cell Differentiation with Single-Cell Resolution. (routledge.com)
While all medical treatments have benefits and risks, unapproved stem cell and exosome products expose patients to potential risks without a clear benefit. (cdc.gov)
Be sure to get all of the facts if you are considering any stem cell treatment. (cdc.gov)
Currently, the only stem cell treatments approved by the Food and Drug Administration (FDA) are products that treat certain cancers and disorders of the blood and immune system. (cdc.gov)
The FDA regulates stem cell and exosome products in the United States. (cdc.gov)
Some clinics may falsely advertise that it is not necessary for FDA to review and approve their stem cell therapies. (cdc.gov)
If you are considering stem cell treatments, check to make sure the product you are considering is on the FDA's approved list of stem cell treatments external icon . (cdc.gov)
If the stem cell product is not on the approved list or if you are considering an exosome product, ask the provider to show you documentation from the FDA and that they have FDA's permission to research the product. (cdc.gov)
Ask for this information before getting treatment-even if the stem cells or exosomes are your own. (cdc.gov)
Patients who have had stem cell or exosome therapy should discuss any concerns and abnormal reactions with their healthcare provider. (cdc.gov)
CDC is investigating bacterial infections in patients who have received stem cell products from the ReGen Series® (distributed by Liveyon, LLC). (cdc.gov)
Most of these patients developed symptoms such as pain, swelling, or chills within a few days of receiving the stem cell products. (cdc.gov)
Then, the scientists used a technique to reprogram these skin cells to make them into cells called induced pluripotent stem cells (iPSCs), which have the potential to become any cell type in the body. (livescience.com)
The study was published July 20 in the journal Cell Stem Cell. (livescience.com)
Immunosuppressed persons, such as stem cell transplant or organ transplant recipients, may require CT scanning to clarify upper respiratory versus lower respiratory infection. (medscape.com)

Scientists studied a new type of cell communication inside the pollen cells of thale cress. (upi.com)
Scientists watched the protein's behavior inside the pollen cells of thale cress, Arabidopsis thaliana , a weed often used as a research model. (upi.com)
Scientists eavesdrop on cell conversations. (zmescience.com)
For their study, the scientists investigated diseased nerve cells using high precision methods and subsequently simulated their electrical properties on the computer. (eurekalert.org)
For their study, the scientists combined experimental research with computer simulations. (eurekalert.org)
Furthermore, using high-precision microscope techniques, the scientists determined the dimensions of healthy and diseased nerve cells. (eurekalert.org)
Dr. Cooper discusses the power of next generation sequencing for the study of evolution, how mutation rates affect evolution, how providing hands-on evolution experiments to high school students can stimulate the next generation of scientists, how scientists need to work to combat public distrust of science, how antibiotic resistance evolves in the presence of immunodeficiency, and how his initial experience with baculoviruses hooked him into a lifelong study of evolution. (apple.com)
His results gave birth to the field of neurophysiology, in which scientists study nerve cells' electrical communication. (sciencenews.org)
Scientists studying the cell's DNA-copying machinery have discovered a molecular mechanism that helps reactivate it should it stop prematurely. (rockefeller.edu)
Scientists have discovered a group of brain cells that may play a role in keeping smokers addicted to nicotine. (rockefeller.edu)
But crucially, this new technique helps scientists to understand why a treatment works or not, by revealing in unprecedented detail how cells are talking to each other. (scienceboard.net)
Moving forward, UCL scientists plan to use this technology to study how tumors from individual patients can uniquely communicate with healthy cells and the immune system. (scienceboard.net)
Scientists used a model of the nasal lining grown from patient nasal biopsy material and used advanced techniques to profile infection and immune responses at the level of single cells. (ncl.ac.uk)
Scientists from the Heidelberg Institute for Theoretical Studies (HITS) performed the computational data analysis for this research. (uni-heidelberg.de)
In a landmark study published in Nature Communications, scientists at Children's Hospital Los Angeles demonstrate an in vitro kidney model that could change the course of research for diseases like CKD. (medindia.net)

Chemical injury induced by DSS leads to a loss of both Lgr5 + cells and Axin2 + cells and epithelial regeneration is driven by Axin2 − cells, including differentiated Krt20 + surface enterocytes. (nature.com)
We demonstrate that Rspo3 is essential for epithelial repair via induction of Wnt signaling in differentiated cells. (nature.com)
For example, in colorectal cancer organoids, epithelial oncogenic mutations mimic signaling networks normally induced by connective tissue cells (stromal cells). (scienceboard.net)
The team found that colorectal cancer developed through successive oncogenic mutations where stromal cells hyper-activated the PI3K signaling pathway in colonic epithelial cells that already carried Kras and Trp53 mutations. (scienceboard.net)
Murine intraepithelial Î³Î´ T cells include distinct tissue-protective cells selected by epithelial butyrophilin-like (BTNL) heteromers. (bvsalud.org)
Immunomodulation of lymphocytes by intestinal epithelial cells could lead to new therapies. (bvsalud.org)

Since 2017, she has studied the communication and social justice issues surrounding Sickle Cell Disease. (memphis.edu)
2017. Genome-wide association study identifies multiple risk loci for renal cell carcinoma. (who.int)

Blood-derived dendritic cells and macrophages, bothantigen-presenting cells, make use of these so-called tunnelingnanotubules to relay molecular messages, report Simon C. Watkins,Ph.D., and Russell D. Salter, Ph.D. Further research may show there areadditional cell types with these microscopic tunnel connections. (sciencedaily.com)
More recently, studies have been performed which have used molecular sequence data to further refine these classifications. (news-medical.net)
An article published in Cell in 2013 summarized for the first time the molecular indicators of aging in mammals. (medscape.com)

However, in Alzheimer's, Parkinson's and in other diseases of the brain, the nerve cells tend to atrophy. (eurekalert.org)
The nerve cells are hyper-excitable. (eurekalert.org)
Our results indicate that if one protects the structure of nerve cells, one also protects their functions. (eurekalert.org)
Persistent blockage can reduce or stop blood flow, limiting the supply of oxygen and nutrients to the surrounding tissue and nerve cells. (nih.gov)
This, in turn, can lead to impaired communications between nerve cells and ultimately cell death. (nih.gov)
The incomplete removal of blockages in the brains of older mice led to a prolonged shortage of oxygen to the surrounding nerve cells and damaged the connections between nerve cells in the vicinity of the obstructed blood vessels. (nih.gov)
The reduced efficiency of this protective mechanism in the older brain and its effect on the function of nerve cells in the brain may significantly contribute to age-related cognitive decline," said Suzana Petanceska, Ph.D., of the Neurobiology of Aging Branch in NIA's Division of Neuroscience, which funded the research. (nih.gov)

Endothelin-1 but not Endothelial Nitric Oxide Synthase Gene Polymorphism is Associated with Sickle Cell Disease in Africa. (rit.edu)
Genomic Polymorphism of CD209 Gene is Associated with Sickle Cell Disease in African Children. (rit.edu)
In addition to several smaller projects, she is a co-investigator on SCDC, a CDC-funded sickle cell disease surveillance project, and SCDCGENE, a collaboration with St. Jude Children's Research Hospital and other institutions that works with sickle cell stakeholders and providers to develop informed consent materials for gene therapy. (memphis.edu)

Furthermore, macrophages were shown to contribute to a niche that can support and maintain a breast CSC (BCSC) phenotype through heterotypic CD90/EphA4 signaling between macrophage and tumor cell 14 . (nature.com)
Using a custom-built, multi-camera live cell microscopicimaging system, they report that, in a matter of seconds, dendriticcells and macrophages can send waves of calcium and other smallmolecules to cells hundreds of micrometers away. (sciencedaily.com)
Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the presence of cells with characteristics similar to bone marrow-derived Langerhans cells juxtaposed against a backdrop of hematopoietic cells, including T-cells, macrophages, and eosinophils. (medscape.com)
Among other cells, monocyte-derived macrophages are centrally involved in such intestinal wound healing. (bvsalud.org)

CSCs display the slow-migratory, invadopod-rich phenotype that is the hallmark of disseminating tumor cells. (nature.com)
60% of circulating tumor cells. (nature.com)
The study used a 3D tumor culture, which more closely replicates how tumors act in the body than other conventional in vitro cell culture models. (naturalpractitionermag.com)
Thusfar, their studies suggest the tunnels do not exist between commonlyused fibroblast and tumor cell lines. (sciencedaily.com)
These tumor specific antigens are the result of mutations that cancer cells undergo, and in many cases that involve viral carcinogens, viral antigens. (oncolink.org)
This approach is based on the view that immune stimulation is primarily mediated by APCs rather than the tumor cells themselves. (oncolink.org)

Studies of identical twins (who share 100 percent of their DNA) and their non-twin siblings (who share about 50 percent of their DNA) show that genetics play a large role. (medlineplus.gov)

However, alterations in cell morphology are typical for all neurodegenerative diseases. (eurekalert.org)
The role of myeloid cells in neurodegenerative diseases. (lu.se)

Humans are complex organisms made up of trillions of cells, and each of these cells has their own structure and function. (zmescience.com)
However, because the study was conducted in mice, more research is needed to determine if the same effects are also seen in humans. (livescience.com)
Moreover, CD103+VÎ³4+cell dysregulation and loss were also displayed by humans with germline BTNL3/BTNL8 hypomorphism, which we identified as a risk factor for penetrating Crohn's disease (CD). (bvsalud.org)

Organoids can be used to model cell-to-cell interactions in vitro, and they represent tissues more accurately than 2D models. (scienceboard.net)
In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (cdc.gov)

Are you ready for your study abroad program? (hartford.edu)
Conduct undergraduate research, complete a cooperative education or internship , or study abroad. (rit.edu)
RIT's Combined Accelerated Bachelor's/Master's Degrees enable you to earn both a bachelor's and a master's degree in as little as five years of study, all while gaining the valuable hands-on experience that comes from co-ops, internships, research, study abroad, and more. (rit.edu)

The platform technology will open new lines of inquiry into research, by providing a unique way to detect how cells talk to each other at a deeper level than what is possible today. (zmescience.com)
Experimental Cell Research. (wikipedia.org)
Cell Biochemistry and Function currently does not publish research in specific areas that are better served by specialist journals. (wiley.com)
Cell Biochemistry & Function also discourages submission of research based exclusively on analysis of publically available transcriptomic and proteomic datasets, although the acceptability of specific manuscripts in this particular area can be discussed with the Editor-in-Chief. (wiley.com)
According to an article from the American Institute for Economic Research, the study argues that the second most dangerous comorbidity for COVID patients is FEAR. (glennbeck.com)
It offers state-of-the-art research and teaching laboratories, seminar rooms, and plenty of study and social space, including a café. (reading.ac.uk)
The opportunity to participate in meaningful, faculty-sponsored undergraduate research projects prepares you to gain valuable experience for full-time employment or to pursue graduate study. (rit.edu)
The authors' discovery builds on their recent research showinghow dendritic cells respond to stimuli, but, as they freely admit inthis paper, it was due in large part to an accidental observation, thatgiving just the slightest poke to a single cell can set off a chainreaction whereby cell after cell discharges bursts of calcium. (sciencedaily.com)
The research was led by research student Guillermo Anderson and Prof. Noa Shenkar of the School of Zoology at the George S. Wise Faculty of Life Sciences and the Steinhardt Museum of Natural History, Israel National Center for Biodiversity Studies, Tel Aviv University. (sciencedaily.com)
Tumour Microenvironment Studies in Immuno-Oncology Research. (routledge.com)
A common theme in my research career has been cell communication. (chatham.edu)
In her PhD research in the Bio-Organic Chemistry group, Marleen van Stevendaal focused on developing synthetic cells that can cooperate well with living tissue. (tue.nl)
Some research was purely chemical, while in others I worked with living cells. (tue.nl)
Dr. Young joined the Department of Communication in 2004, after serving as director of communication research at the VA Pittsburgh Healthcare System in Pittsburgh, PA, for 5 years. (memphis.edu)
Her research in health communication has focused on rhetorical agency in patient/provider interactions in chronic illness, as well as geriatrics, end-of-life care, public health communication, and health literacy. (memphis.edu)
Agency and communication challenges in discussion of informed consent in pediatric cancer research. (memphis.edu)
Her research work was focused on investigating the role of an extracellular matrix protein (fibronectin) on mediating cell-material interactions. (gla.ac.uk)
Organoids are already revolutionizing cancer research by allowing us to test whether experimental new drugs are effective on lifelike models of tumors," said lead study researcher Chris Tape, PhD, from UCL, in a statement by Cancer Research UK. (scienceboard.net)
Further research will focus on the role of immune cells present in the nose in strengthening the interferon response. (ncl.ac.uk)
Now, new research from the University of Pittsburgh School of Medicine suggests that astrocytes, which are star-shaped brain cells, play a crucial role in determining the progression of Alzheimer's. (medicalnewstoday.com)
Dr. Keith Vossel , professor of neurology and director of the Mary S. Easton Center for Research and Care at the University of California, Los Angeles, not involved in the research, told MNT that "once considered glue-like cells, astrocytes have many important functions in the brain, including immune functions and regulating brain activity. (medicalnewstoday.com)
According to research studies on the use of mobile phone for the educational purpose in Sri Lanka, the course is to let the students collecting the information for the development of lesson about what they use at their household by using their phone, and they have to transfer the collected information to the lecturer's laptop via Bluetooth device. (bartleby.com)
Students who use cell phones to access research information are able to reach a wide variety of current information. (bartleby.com)
Dr. Perin and Dr. Da Sacco conduct research in the GOFARR Laboratory for Organ Regenerative Research and Cell Therapeutics in Urology along with co-director Roger De Filippo, MD, at CHLA's Saban Research Institute. (medindia.net)
The lead author on the study was CHLA postdoctoral research fellow Astgik Petrosyan. (medindia.net)
Increasing availability of affordable cell phone technologies may provide an opportunity for research follow-up among construction workers once they leave the worksite. (cdc.gov)
Further research on frequency of cell phone use and types of email/texting services used by construction workers are needed. (cdc.gov)
María A. Blasco, MD, scientific director of the National Cancer Research Center, an international leader in telomere research and co-author of the study, noted on the institution's website, "The spectacular advances in recent years to increase the longevity of model organisms, including in mammals, indicate that it will be important to develop rational strategies to intervene in human aging. (medscape.com)

Updated February 2022 by Mohammad Ursani, MD, and reviewed by the American College of Rheumatology Committee on Communications and Marketing. (rheumatology.org)

In the colon, this process has not been investigated in detail, but recent studies demonstrated the ability of Atoh1 + secretory cells to partially restore depleted Lgr5 + cells 5 , 6 . (nature.com)
Experts at Newcastle University have found that all nasal cell types are vulnerable to infection and that some, such as ciliated and secretory cells, support even greater levels of infection. (ncl.ac.uk)

Elucidating the cell signals that regulate transporter function may help to explain mechanisms of neurodegeneration and psychiatric disorders, such as drug addiction. (chatham.edu)
The synthetic cells cannot yet regulate the protein release needed for this form of communication via the pores located on an organic cell's membrane - but van Stevendaal found a solution to this. (tue.nl)

As noted above, a more vigorous dendritic cell presentation of antigens could trigger the immune response by T-cells. (oncolink.org)
The working group of the Histiocyte Society divided histocytic disorders into three groups: (1) dendritic cell histiocytosis, (2) macrophage-related disorders, and (3) malignant histiocytosis. (medscape.com)

Open projects in the laboratory use mammalian cell culture, immunocytochemistry, microscopy, and behavioral analysis of the microscopic roundworm C. elegans. (chatham.edu)

Nature Communications DOI: 10.1038/ncomms15724. (who.int)

To study how tissues function, we need a model that measures both how signals are transmitted between cells and how this information is processed within cells, and these models become much less variable when combined with CITE-seq or scRNA-seq, CyTOF, and CellPhoneDB. (assay-engineers.com)
Finally, it must be possible to incorporate the synthetic cells into the complex environment of living cells and tissues. (tue.nl)
In the cancer organoids, the cancer cells themselves (as well as the immune cells and stromal tissues) had "rewired" normal signaling, which allowed tumors to grow unchecked. (scienceboard.net)
Mechanochemical Principles of Spatial and Temporal Patterns in Cells and Tissues. (mpi-cbg.de)
Patterns are ubiquitous in living systems and underlie the dynamic organization of cells, tissues, and embryos. (mpi-cbg.de)

Furthermore, they must have a communication system through which living cells can respond and modify their behavior. (tue.nl)
Our new technology allows us to simultaneously measure the behavior of cancer cells, healthy cells, and immune cells from minitumors [organoids]," said Tape. (scienceboard.net)

Qualitative Dynamical Modelling of T-Helper Cell Differentiation and Reprogramming. (routledge.com)

On Target 3 , on-going studies aim to modulate GabR-dependent transcription regulation to weaken bacterial stress response. (luc.edu)

A new article examines how different cell types within the TME work together to drive cancer and considers the multiple signals present between and within different cancers. (assay-engineers.com)
Immune system cells are connected to each other by an extensive network of tiny tunnels that, like a building's hidden pneumatic tube system, are used to shoot signals to distant cells. (sciencedaily.com)
February 18, 2020 -- A new technique using organoids, self-organizing 3D tissue models, can decipher how individual cancer cells communicate with each other and the unique signals they create. (scienceboard.net)

Unlike glutamate receptors in animals, which are found on the outside of cells, GLRs are most common on structures inside the walls of plant cells. (upi.com)
Subsequent analysis show that EVs transfer their functionally active receptors to target cells, making them prone to an otherwise unresponsive state. (lu.se)
Therefore, antipsychotic drugs work by blocking receptors so that communication between groups of cells is reduced. (msdmanuals.com)

Marleen van Stevendaal has researched how communication between synthetic cells and living tissue can be controlled using chemokines. (tue.nl)
In normal tissue organoids, the cells regulated only acute signaling fluxes. (scienceboard.net)
2021. Sexual Dimorphism in Cancer: Insights from Transcriptional Signatures in Kidney Tissue and Renal Cell Carcinoma. (who.int)
Thus, BTNL-dependent selection and/or maintenance of distinct tissue-intrinsic Î³Î´ T cells appears to be an evolutionarily conserved axis limiting the progression of a complex, multifactorial, tissue-damaging disease of increasing global incidence. (bvsalud.org)

Our study focused on Alzheimer's. (eurekalert.org)
The abnormal reactivity of a group of brain cells called astrocytes is crucial to patients [who] develop Alzheimer's disease. (medicalnewstoday.com)
This brain cell abnormality can be measured with a simple blood test, enabling us to identify cognitively healthy individuals at risk of developing Alzheimer's disease. (medicalnewstoday.com)
The study findings carry significant implications for future clinical trials of potential Alzheimer's drugs. (medicalnewstoday.com)
This study] supports GFAP as a useful blood test to predict future progression to Alzheimer's disease in cognitively normal people who have amyloid buildup in the brain, which would be helpful for future clinical trials that select cohorts of patients at highest risk of developing Alzheimer's. (medicalnewstoday.com)

We have successfully encapsulated Spn cells, and their signaling molecules, in these miniature bioreactors. (aiche.org)
Spn undergoes multiple rounds of division within the droplets, providing an optimal opportunity to quantify the association between cell-cell signaling, cell density, and environmental factors such as nutrient availability, pH, oxygen and temperature. (aiche.org)
We have captured cell-density dependent PhrA signaling in a droplet at a single-cell level. (aiche.org)
We are currently quantifying the association between cell number and signaling, and its dependence on environmental conditions. (aiche.org)
In the long term, we hope to shed light on the relationship between the kinetics of Spn cell-cell signaling, environmental conditions, and virulence, and to exploit this knowledge for the development of anti-pneumococcal therapies. (aiche.org)
We identify two populations of cells with active Wnt signaling: highly proliferative Lgr5 + /Axin2 + cells, as well as secretory Lgr5 − /Axin2 + cells. (nature.com)
This cooperation could make it possible to eventually apply synthetic cells to the targeted delivery of signaling molecules, for example. (tue.nl)
Using this model, they found that cell-type-specific signaling networks are intimately linked with cell state. (scienceboard.net)
Images highlight signaling networks within organoid cells and signaling relationships. (scienceboard.net)
They were able to simultaneously detect 28 key signaling molecules across six different cell-types in over 1 million cells. (scienceboard.net)
Our findings reveal that fusion renders non-responsive cells susceptible to inflammatory signaling, as evidenced by increased NF-κB activation and the release of inflammatory mediators. (lu.se)

Dr Christopher Duncan , from Newcastle University's Faculty of Medical Sciences and Honorary Consultant in Infectious Disease at The Newcastle upon Tyne Hospitals NHS Foundation Trust , who led the study, says the findings could help to inform the development of future treatments to prevent infection. (ncl.ac.uk)
The findings of this study argue that glial cell dysfunction may be the basis of childhood-onset schizophrenia," Dr. Steve Goldman, co-director of the Center for Translational Neuromedicine at the University of Rochester Medical Center and lead author of the study, said in a statement . (livescience.com)
[ 3 ] Taken together, these findings have led some to speculate that LCH is not a specific disease of epidermal Langerhans cells, but rather one of mononuclear phagocyte dysregulation. (medscape.com)

Students who enroll in a qualifying undergraduate degree have the opportunity to enroll in the +1 MBA program by adding an MBA to their bachelor's degree after their first year of study. (rit.edu)

Recent advances in structure determination of the extracellular regions of human Notch-1 and one of its ligands Jagged-1 have given new insights into docking events occurring at the cell surface which may facilitate the development of new highly specific therapies. (nih.gov)

Virtually all aspects of life and disease depend of brief exchanges between cells. (rockefeller.edu)
Despite the importance of PTM in disease, and the development of organoids to study diseases, the technology to analyze cell-type-specific PTM networks in organoids has not been previously developed. (scienceboard.net)
Profiling the immune response of nasal cells, they found the way the nose lining reacts to the SARS-CoV-2 virus, which causes Covid-19, and the immune response it sets off in the body could determine disease and outcome. (ncl.ac.uk)
But the University of Pittsburg study challenges this notion and sheds light on the critical role of astrocytes in brain health and disease. (medicalnewstoday.com)
But the authors said the chimeric mice that were developed in this study could be used in the future to test new treatments for schizophrenia, and thus speed up the process of finding new therapies for the disease. (livescience.com)
While this seemed a distant goal in the past, Dr. Da Sacco and Dr. Perin are already recreating and studying the disease state in their model. (medindia.net)
Similar studies for women have addressed cardiovascular disease (16), emotional health (17), and obesity (18). (cdc.gov)
Towards cell replacement therapy in Parkinson's disease. (lu.se)
Human metapneumovirus (hMPV) is difficult to grow in cell culture, largely explaining the delay in recognizing this pathogen, which has been causing disease for 50 years. (medscape.com)
This subset was disproportionately diminished and dysregulated in inflammatory bowel disease, whereas on-treatment CD103+Î³Î´ T cell restoration was associated with sustained inflammatory bowel disease remission. (bvsalud.org)
The Mediterranean diet has been shown in different studies to be associated with a lower cardiovascular risk (stroke, ischemic heart disease , dyslipidemia) and a lower risk of cognitive impairment, especially due to its vascular component. (medscape.com)

It is required for various cell fate decisions at multiple stages of development and in the adult organism, with dysregulation of the pathway associated with genetic and acquired diseases including cancer. (nih.gov)
Its use in other diseases is still being studied. (rheumatology.org)
This makes them ideal for studying multicellular diseases such as cancer. (scienceboard.net)
The new study includes a table with almost 80 recent experimental interventions with mammals (mostly mice) that suggest that it is possible to prolong life or treat age-associated diseases. (medscape.com)
Javier Gómez Pavón, MD, head of geriatrics at Red Cross Hospital in Madrid and member of the leadership team of the Spanish Society of Geriatrics and Gerontology, told Medscape Spanish Edition, "Currently, the evidence we have indicates that certain types of diet in population cohort studies are associated with a lower incidence and prevalence of certain diseases. (medscape.com)

While receptor antagonists were unable to inhibit NF-κB activation, blocking of the fusion between EVs and their target cells with heparin mitigated inflammation in mice challenged with EVs. (lu.se)
A receptor on the receiving cell detects the neurotransmitter, which causes the receiving cell to generate a new impulse. (msdmanuals.com)

These cytokines are used in the immune system for cell-to-cell communication. (oncolink.org)
Arguments supporting the reactive nature of LCH include the occurrence of spontaneous remissions, the extensive elaboration of multiple cytokines by dendritic cells and T-cells (the so-called cytokine storm) in LCH lesions, and the good survival rate in patients without organ dysfunction. (medscape.com)

Further study may help us better understand how they'reinvolved in the local inflammatory response of the immune system. (sciencedaily.com)
Abatacept attaches to the surface of inflammatory cells and blocks communication between these cells. (rheumatology.org)
Microbial colonization of the mammalian intestine elicits inflammatory or tolerogenic T cell responses, but the mechanisms controlling these distinct outcomes remain poorly understood, and accumulating evidence indicates that aberrant immunity to intestinal microbiota is causally associated with infectious, inflammatory and malignant diseases1-8. (bvsalud.org)
Here we define a critical pathway controlling the fate of inflammatory versus tolerogenic T cells that respond to the microbiota and express the transcription factor RORÎ³t. (bvsalud.org)

We started our communication system with a 'model' protein around our synthetic cells so that we could properly characterize our system with the microscope. (tue.nl)
on-going studies aim to employ lactonase as a protein therapeutic to disrupt bacterial cell-to-cell communication, quorum-quenching. (luc.edu)

She participates in multidisciplinary projects to decipher cell mechanisms rewiring in cancer. (routledge.com)

In certain lymphomas, the immunoglobulin antigen that the lymphoid cell is supposed to be producing becomes mutated, and hence a potential target for vaccines. (oncolink.org)

Nat Rev Mol Cell Biol , Art. (mpi-cbg.de)

Forinstance, we may find that dendritic cells use this network todistribute antigens to other cells and it may be conceivable to followthe entire pathway by tracing the network of tunneling nanotubules,"said Dr. Salter. (sciencedaily.com)
Rather than attempting to determine the exact antigen on the cancer cells themselves, an alternative approach has been to isolate and to study the immunogobulins that our bodies have produced in recognition of these foreign antigens. (oncolink.org)
These cells, such as dendritic cells, process foreign antigens and then present them to T-cells, causing their intense activation. (oncolink.org)

A new study suggests that astrocytes, a type of brain cell, are important for connecting amyloid-β with the early stages of tau pathology. (medicalnewstoday.com)

Cell phone and hand isolates exhibited substantial clonal diversity. (cdc.gov)

This constant replacement of the epithelium is driven by cells located in the base of colonic crypts, which constantly divide and give rise to the various differentiated cell types. (nature.com)
This has been studied mainly in the small intestine, where different cell types such as enterocyte progenitors 4 , more differentiated secretory Bmi1 + cells 3 , or even fully differentiated Paneth cells can repopulate crypts upon injury. (nature.com)
The authors are the first to explain the function of tunnelingnanotubules, structures that were first described in fruit flies in1998, and subsequently, identified in a handful of different types ofanimal and human cells. (sciencedaily.com)
A new study compares the effects of two types of disposable dishes on the marine environment -- regular plastic disposable dishes and more expensive bioplastic disposable dishes certified by various international organizations -- and determines that the bioplastic dishes had a similar effect on marine animals as regular plastic dishes. (sciencedaily.com)
A new Tel Aviv University study compares the effects of two types of disposable dishes on the marine environment -- regular plastic disposable dishes and more expensive bioplastic disposable dishes certified by various international organizations -- and determines that the bioplastic dishes had a similar effect on marine animals as regular plastic dishes. (sciencedaily.com)
A cell platform means that we have a basic method with which we can mimic different types of cell aspects with exactly the properties we are looking for. (tue.nl)
First, we investigated how the use of structure and materials and the construction of these synthetic cells affect the viability of different cell types. (tue.nl)

On Target 2, on-going studies aim to inhibit acylase to disrupt bacterial iron acquisition. (luc.edu)
In addition, the study identified chemical imbalances that disrupt communication among brain cells, and these imbalances could be a target for new therapies, the authors said. (livescience.com)

What's more, glutamate is much more important to neuronal function in animals than it is to communication among plant cells. (upi.com)

Our results support the idea that individual plant cells have a level of autonomy that animal cells do not," Feijó said. (upi.com)
Moving toward patient autonomy: A case study of communication in adolescent cystic fibrosis care. (memphis.edu)

Cell-cell communication drives cancer progression and influences therapy response. (assay-engineers.com)

A huge genetic study that sought to pinpoint how the human genome is evolving suggests that natural selection is getting rid of harmful genetic mutations that shorten. (acm.org)

A multigeneration study to ascertain the toxicological effects of Great Lakes salmon fed to rats: Study overview and design. (cdc.gov)
It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. (cdc.gov)

Anatomy4

Organisms1

Diseases1

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Psychiatry and Psychology6

Phenomena and Processes6

Information Science7

Health Care4

Biology15

Researchers24

Neurons13

Proteins18

Cellular14

Intercellular communication4

Stem33

Scientists15

Epithelial6

20172

Molecular3

Nerve cells7

Sickle cell di3

Macrophages4

Tumor6

Genetics1

Neurodegenerative diseases2

Humans3

Vitro2

Abroad3

Research28

20221

Secretory cells2

Regulate2

Dendritic cell2

Mammalian cell1

10.10381

Tissues5

Behavior2

Differentiation1

Regulation1

Signals3

Receptors3

Tissue4

Alzheimer's5

Signaling11

Findings3

Bachelor's1

Extracellular1

Disease11

Diseases5

Receptor2

Cytokines2

Inflammatory4

Protein2

Mechanisms1

Lymphoid1

Biol1

Antigens3

Astrocytes1

Clonal1

Types7

Disrupt2

Neuronal1

Autonomy2

Progression1

Human genome1

Toxicological2