• Studies set in infertility clinics have the advantage of investigating obesity trends within infertile populations whereas populations of unselected healthy men across BMI categories enable evaluation of the association between obesity and fertility without a preconceived bias. (medscape.com)
  • Male obesity and infertility: observational studies of sperm parameters and BMI. (medscape.com)
  • Support relationship between obesity and male infertility? (medscape.com)
  • Secondary infertility refers to infertile couples who have been able to achieve pregnancy at least once before (with the same or different sexual partner). (uroweb.org)
  • In 50% of involuntarily childless couples, a male-infertility-associated factor is found, usually together with abnormal semen parameters [ 1749 ]. (uroweb.org)
  • In 30-40% of cases, no male-associated factor is found to explain the underlying impairment of sperm parameters and historically was referred to as idiopathic male infertility. (uroweb.org)
  • Unexplained male infertility is defined as infertility of unknown origin with normal sperm parameters and partner evaluation. (uroweb.org)
  • It is now believed that idiopathic male infertility may be associated with several previously unidentified pathological factors, which include but are not limited to endocrine disruption as a result of environmental pollution, generation of reactive oxygen species (ROS)/sperm DNA damage, or genetic and epigenetic abnormalities [ 1753 ]. (uroweb.org)
  • Advanced paternal age has emerged as one of the main risk factors associated with the progressive increase in the prevalence of male factor infertility [ 1754-1761 ]. (uroweb.org)
  • Table 52 summarises the main male-infertility-associated factors. (uroweb.org)
  • MATERIALS AND METHODS: Clinicians managing male infertility were invited to complete an online survey on practices related to SDF diagnostic and treatment approaches. (bvsalud.org)
  • Possible explanations why these population studies are not more consistent could include lack of sensitivity of BMI as a measurement of adiposity, presence of subfertility, which may manifest by more subtle changes in testicular/sperm physiology not captured by traditional semen assessments, and finally, heterogeneity within the overweight/obese populations. (medscape.com)
  • Semen quality is a measure of male fertility, a measure of the ability of sperm in semen to accomplish fertilization. (wikipedia.org)
  • A 2017 review and meta-analysis found sperm counts among Western men (i.e. men in Australia, Europe, New Zealand, and North America) declined 50-60% between 1973 and 2011, with an average decline of 1.4% per year. (wikipedia.org)
  • The decline in sperm count among men in South America, Asia, and Africa is less than men in Western countries, though the amount of decline in these regions is uncertain. (wikipedia.org)
  • Although it is possible for men to father children into old age, the genetic quality of sperm, as well as its volume and motility, all typically decrease with age. (wikipedia.org)
  • In men with a normal level of sperm production (normozoospermia), the percentage of sperm DNA fragmentation is positively correlated with age, and inversely correlated with progressive sperm motility. (wikipedia.org)
  • While advanced age can be a possible factor in sperm motility and health, the sperm of men below 20 years of age has likewise been linked to an increase in birth defects such as neural tube defects, hypospadias, cystic kidney, and Down syndrome. (wikipedia.org)
  • Likewise, advanced maternal age must be considered in the management of every infertile couple, and in the subsequent decisions in the diagnostic and therapeutic strategy of the male partner [ 1762 , 1763 ]. (uroweb.org)
  • These men present with no previous history of diseases affecting fertility and have normal findings on physical examination and endocrine, genetic and biochemical laboratory testing, although semen analysis may reveal pathological findings (see Section 11.3.2). (uroweb.org)
  • For this reason, in all infertile couples the male should undergo medical evaluation by a urologist trained in male reproduction. (uroweb.org)
  • PURPOSE: This is the first study to design and assess a research capacity building (RCB) specifically tailored for clinical and non-clinical andrology practitioners worldwide. (bvsalud.org)
  • One particularly well-studied connection is the link between advancing age and autism. (wikipedia.org)