• Specifically, our aim is to localize an iodine-labelled phenylalanine in the SARS E protein, incorporated in DMPC phospholipid bilayers, which are deposited in the form of thick multilamellar stacks on silicon surfaces. (huji.ac.il)
  • Orientational dynamics of water in phospholipid bilayers with different hydration levels. (bvsalud.org)
  • We performed molecular dynamics computer simulations to study the orientational dynamics of water next to bilayers containing dilauroyl phosphatidylcholine (DLPC) phospholipids with different hydration levels from 2 to 32 water molecules per lipid . (bvsalud.org)
  • We also studied hydrogen bonding properties of water and found that hydrogen bonding switch between water molecules is responsible for a substantial orientational relaxation and that this switch can be explained by the molecular jump model (MJM) in the hydration region of lipid bilayers , as it does in bulk water . (bvsalud.org)
  • CCT is a key enzyme that maintains a balanced composition of cell membrane phospholipids. (asbmb.org)
  • We now investigated the effect of NMDA receptor overactivation on synthesis and degradation of major membrane phospholipids in the early stages of the excitotoxic process. (jneurosci.org)
  • These results show that membrane damage by NMDA is preceded by inhibition of phospholipid synthesis and not by phospholipid degradation in the early stages of the excitotoxic process, and that NMDA receptor overactivation decreases phosphatidylcholine and phosphatidylethanolamine synthesis by inhibiting choline-ethanolaminophosphotransferase activity. (jneurosci.org)
  • Enzymatic hydrolysis of membrane phospholipids by phospholipases produces these lipid second messengers, as well as soluble second messengers such as inositol 1,4,5-trisphosphate, and also other molecules such as choline (Cho) that are released to the extracellular medium. (jneurosci.org)
  • It is generally assumed that enzymatic hydrolysis of phospholipids leads to phospholipid degradation and membrane damage. (jneurosci.org)
  • Phospholipid fatty acids are a main component of the cell membrane ("the skin") of all microbes. (microbe.com)
  • Dr. Maher Fuad, a well-respected research clinician at the Fonterra Research and Development Centre (FRDC), is preparing to unveil ground breaking discoveries regarding the impact of Nutiani Phospholipids [sourced from milk fat globule membrane (MFGM)] supplementation on psychological well-being. (fonterra.com)
  • We report on an anomalous X-ray reflectivity study to locate a labelled residue of a membrane protein with respect to the lipid bilayer. (huji.ac.il)
  • Furthermore, gram-negative bacteria and mitochondria both have a double phospholipid membrane layer-the inner and outer membrane. (nature.com)
  • The inner membrane encapsulates the cytosol of gram-negative bacteria and the matrix of mitochondria and is rich in the phospholipid cardiolipin. (nature.com)
  • The cell membrane holds together because its components-called phospholipids-are dual-personality molecules that have an oil-loving tail and a water-loving head. (psc.edu)
  • To escape the water that both fills and surrounds living cells, the membrane forms as two sheets-leaflets-of phospholipids. (psc.edu)
  • So the cell membrane has different types of phospholipids in its inner and outer leaflets. (psc.edu)
  • This is important because the "wrong" phospholipids showing up on the outside leaflet of the membrane serve as a red flag that a cell has developed a serious problem. (psc.edu)
  • Understanding how the cell creates and maintains the mix of phospholipids in their inner and outer membrane leaflets is an important question for a number of human diseases. (psc.edu)
  • These membrane-embedded proteins scramble the proper mix of phospholipids by flipping them in and out. (psc.edu)
  • Cell membrane, showing the two leaflets, each made up of phospholipids with water-loving heads (yellow circles) facing out and fat-loving tails (gray zigzags) facing in. (psc.edu)
  • Khelashvili and Weinstein turned Anton 2 to try to simulate how a family of scramblases called TMEM16 help phospholipids flip to the opposite side of the cell membrane. (psc.edu)
  • Previous laboratory work by other scientists had given rise to the idea that two slots at either end of the TMEM16 scramblase helped the phospholipids flip through from one side to the other by hiding their water-loving heads from the oil-loving interior of the membrane. (psc.edu)
  • The current study reports data on the membrane properties of the phytosterol (3β,5α,22 E )-stigmasta-7,22-dien-3-β-ol (α-spinasterol), which represents an important component of argan oil and have not been investigated so far in molecular detail. (mdpi.com)
  • This asymmetry is maintained by the Mla pathway, a six-component system that is widespread in Gram-negative bacteria and is thought to mediate retrograde transport of misplaced phospholipids from the outer leaflet of the OM to the cytoplasmic membrane 4 . (nature.com)
  • MlaC probably accepts a phospholipid from MlaA and shuttles it to the ABC transporter for ATP-dependent plasma membrane insertion 5 . (nature.com)
  • While many studies have been focused on the membrane structure, the dynamics of such systems are crucial for the function of the membrane including membrane bound proteins. (lu.se)
  • The contents of surfactant protein A and albumin in exhaled particles was quantified with immunoassays and the contents of the phospholipids dipalmitoyl- and palmitoyl-oleoyl- phosphatidylcholine with mass spectrometry . (bvsalud.org)
  • In this work, a systematic study using an atomic force microscope (AFM) was carried out to understand the effect of cholesterol on the nanomechanical stability of two saturated phospholipids, DSPC (1,2-distearoyl-sn-glycero-3-phosphatidlycholine) and DPPC (1,2-dipalmitoyl-sn-glycero- phosphatidylcholine), that differ in acyl chain lengths. (epj.org)
  • Interactions of vesicles of dipalmitoyl phosphatidylcholine with the anti-inflammatory agents sulindac sulfide, naproxen, phenylbutazone, and indomethacin and the structurally related physiologically inactive compounds sulindac, sulindac sulfone, and 5-methoxy-2-methyl-indole-3-acetic acid were studied by differential scanning calorimetry and by the measurement of nuclear Overhauser effects (NOEs), using 1D- and 2D-NMR methods. (northumbria.ac.uk)
  • METHODS: The amount and composition of phospholipid classes and phosphatidylcholine molecular species were determined in bronchoalveolar lavage (BAL) fluid and lavaged lungs by high performance liquid chromatography (HPLC). (bmj.com)
  • The amount of SP-A in BAL fluid and the composition of phospholipid as well as phosphatidylcholine molecular species in BAL fluid and lung tissue was unchanged in cftrm1HGU/m1HGU mice compared with controls. (bmj.com)
  • In the current study, diabetes-induced lipid peroxidation in rat liver microsomal membranes was investigated by Fourier transform infrared (FT-IR) spectroscopy at different temperatures. (metu.edu.tr)
  • As we have previously demonstrated that mechanical robustness improves the tribological performance of lipid layers, this study helps to shed light on the mechanism of physiological lubrication. (epj.org)
  • MlaA represents a lipid transport protein that selectively removes outer leaflet phospholipids to help maintain the essential barrier function of the bacterial OM. (nature.com)
  • We prospectively investigated the relation of plasma cholesterol ester (CE) and phospholipid (PL) fatty acid composition with the incidence of diabetes mellitus. (nih.gov)
  • Axinella corrugata, Dragmacidon alvarezae, Dragmacidon reticulatum, Ptilocaulis walpersi, Myrmekioderma rea and one sponge belonging to the order Scopalinida: Scopalina ruetzleri were analyzed to assess their fatty acid composition in the phospholipid fraction. (usp.br)
  • As part of a stable isotope probing (SIP) study, phospholipid fatty acid analysis helps answer the question "Is biodegradation is occurring? (microbe.com)
  • Stable isotope probing (SIP) studies using Bio-Traps® amended with 13C benzene or 13C naphthalene conclusively demonstrated in situ biodegradation occurred under existing site conditions. (microbe.com)
  • Marine sediment slurries enriched for anaerobic, sulfate-reducing prokaryotic communities utilizing glucose and acetate were used to provide the first comparison between stable-isotope probing (SIP) of phospholipid fatty acids (PLFA) and DNA (16S rRNA and dsrA genes) biomarkers. (cardiff.ac.uk)
  • Oxidized phospholipids on apolipoprotein B-100 versus plasminogen and risk of coronary heart disease in the PROCARDIS study. (ox.ac.uk)
  • BACKGROUND AND AIMS: Oxidized phospholipids carried on the apolipoprotein B-100 (OxPL-apoB) component of Lp(a) are predictive of coronary heart disease (CHD), but the role of oxidized phospholipids carried on plasminogen (OxPL-PLG) is unknown. (ox.ac.uk)
  • A new study aims to elucidate the relationship of plasma Lp(a) and oxidized phospholipids to acute coronary events. (medscape.com)
  • Interaction of phospholipid vesicles with cultured mammalian cells. (rupress.org)
  • Lasonder, E & Weringa, WD 1990, ' An NMR and DSC study of the interaction of phospholipid vesicles with some anti-inflammatory agents ', Journal of Colloid and Interface Science , vol. 139, no. 2, pp. 469-478. (northumbria.ac.uk)
  • DEA-derived phosphoglycerides constituted the majority of aberrant phospholipid following acute administration. (rti.org)
  • Antibodies to phospholipids have been found in 80% of patients in a large series of acute Q fever ( 9 ). (cdc.gov)
  • However, one study of children with acute lymphoblastic leukemia demonstrated that ultrasonography was insensitive for DVT in the superior vena cava, subclavian veins, or brachiocephalic veins. (medscape.com)
  • The leaflets are different from one another in terms of composition … There's a compositional asymmetry, with different phospholipids in the outer leaflet versus the inner leaflet. (psc.edu)
  • Here we show, using X-ray crystallography, molecular dynamics simulations and in vitro and in vivo functional assays, that MlaA is a monomeric α-helical OM protein that functions as a phospholipid translocation channel, forming a ~20-Å-thick doughnut embedded in the inner leaflet of the OM with a central, amphipathic pore. (nature.com)
  • This architecture prevents access of inner leaflet phospholipids to the pore, but allows outer leaflet phospholipids to bind to a pronounced ridge surrounding the channel, followed by diffusion towards the periplasmic space. (nature.com)
  • The results of some epidemiologic studies conducted by using questionnaires suggest that dietary fat composition influences diabetes risk. (nih.gov)
  • We aimed to explore the effect of smoking on the composition and number of exhaled particles in a smoker -enriched study population . (bvsalud.org)
  • Lung surfactant in a cystic fibrosis animal model: increased alveolar phospholipid pool size without altered composition and surface tension function in cftrm1HGU/m1HGU mice. (bmj.com)
  • A study was therefore undertaken to investigate the pool sizes, composition, and function of lung surfactant in the non-infected cftrm1HGU/m1HGU mouse. (bmj.com)
  • Only the Mla system maintains asymmetry directly via phospholipid extraction, while PldA and PagP both generate lysophospholipids in the outer leaflet that still require removal. (nature.com)
  • In collaboration with teams from The University of Auckland and the University of Otago, Dr. Fuad ran a 12-week clinical trial aimed at investigating the effects of phospholipid supplementation via MFGM source on mental well-being in healthy adults facing moderate stress. (fonterra.com)
  • The second study looked at the influence of supplementation via differences achieved in Activities of Daily Life scores and other domains of deterioration and stability, including Alzheimer's disease pathology, in a group of elderly participants diagnosed with AD. (nutraceuticalsworld.com)
  • Pioneered by Microbial Insights founder Dr. D.C. White, phospholipid fatty acid analysis (PLFA) is used to quantify total viable biomass and provide a general profile of the microbial community. (microbe.com)
  • The mesoscale, particle-based modelling approach allows the examination of large-scale self-assembly response of dipalmitoylphosphatidylcholine (DPPC) phospholipids in a model bio oil solvent (modelled by triglycerides) in the presence of varying amounts of water. (aalto.fi)
  • For DPPC with 10 mol % cholesterol, the effect of tip properties and the experimental procedure parameters on the breakthrough forces were also studied. (epj.org)
  • However, the mechanisms by which phospholipases switch from physiological second-messenger production to phospholipid degradation remain unclear. (jneurosci.org)
  • METHODS: Plasma levels of OxPL-apoB, OxPL-PLG, plasminogen and Lp(a) were measured in the PROCARDIS study of early-onset CHD (906 cases/858 controls). (ox.ac.uk)
  • Methods: We used the European EPIC-InterAct case-cohort study including 11,124 incident adult-onset diabetes cases and a subcohort of 14,866 randomly selected individuals. (lu.se)
  • An important part of the experimental studies is an ongoing improvement of methods. (lu.se)
  • Lipoprotein(a) and Oxidized Phospholipids: Partners in Crime? (medscape.com)
  • MlaA is the most enigmatic Mla component, particularly since its identity as a periplasmically exposed lipoprotein appears hard to reconcile with its proposed activity on outer leaflet phospholipids. (nature.com)
  • The results show water content vs phospholipid concentration dependent transitions in reverse micellar to network-like and various lamellar phases in bulk assembly. (aalto.fi)
  • Levels of 31 different fatty acids from serum phospholipids were determined by GC-MS and reported in relative (mol%) and absolute concentration (μmol l −1 ) units. (lu.se)
  • The absolute concentration of total phospholipid fatty acids changed rapidly in the first weeks of life, peaking at day 3, median (Q1-Q3) 4452 (3645-5466) μmol l −1 , and was positively correlated to the intake of parenteral lipids. (lu.se)
  • [ 2 ] This is likely due to the class and concentration of phospholipids because certain studies have reported abolishing the LA effect on the aPTT when reagents rich in phosphatidyl serine are used. (medscape.com)
  • For LA, demonstrating how its activity specifically depends on phospholipid concentration is key. (medscape.com)
  • Current smoking alters phospholipid- and surfactant protein A levels in small airway lining fluid: An explorative study on exhaled breath. (bvsalud.org)
  • BACKGROUND: Progressive pulmonary dysfunction is a characteristic symptom of cystic fibrosis (CF) and is associated with functional impairment and biochemical alterations of surfactant phospholipids in the airways. (bmj.com)
  • CONCLUSION: In cftrm1HGU/m1HGU mice surfactant homeostasis is perturbed by an increased phospholipid pool in the alveolar compartment. (bmj.com)
  • Thus this study evaluates the effect of Phospholipid complex of naringenin on various clinical parameters. (pnrjournal.com)
  • Clonal Hematopoiesis in Patients With ASCVD A new study provides strong evidence of the significant clinical impact of clonal hematopoiesis of indeterminate potential in patients with atherosclerotic cardiovascular disease. (medscape.com)
  • Its main objectives are to investigate the causes and prevention of cancer in association with diet (including biomarkers of diet), obesity, physical inactivity and endogenous hormones, through different existing (e.g. the EPIC study) and new epidemiological and clinical studies in developed and middle- and low-income countries. (who.int)
  • In conclusion the Phospholipid naringenin complex have potential for treating diabetes. (pnrjournal.com)
  • Adjusted Prentice-weighted Cox regression estimated HRs and 95% CIs of diabetes in relation to 1 SD lower plasma phospholipid 15:0 and/or 17:0 concentrations or their main contributor, dairy intake, among GAD65Ab-negative and -positive individuals. (lu.se)
  • Conclusions/interpretation: Low plasma phospholipid 17:0 concentrations may promote the progression from GAD65Ab positivity to adult-onset diabetes. (lu.se)
  • Exclusion criteria were diabetes, phospholipids. (who.int)
  • Examination of the DPPC adsorption to smooth, homogeneous adsorbate surfaces of differing polarity reveals that phospholipid adsorption response transitions between discrete assemblies on polyethylene-like hydrophobic to continuous coating on mica-like hydrophilic substrates as the function of phospholipid and water concentrations. (aalto.fi)
  • We reviewed a few plausibly organic syntheses of phospholipids under prebiotic conditions with special attention paid to the starting materials as pro-chiral dihydroxyacetone and dihydroxyacetone phosphate (DHAP), which are the key molecules to break symmetry in phospholipids. (mdpi.com)
  • The deleterious effects of Mla knockouts probably result from phospholipid accumulation in the OM outer leaflet, forming bilayer patches that are portals for entry of lipophilic small molecules 17 . (nature.com)
  • Internal sodium ions and water molecules in guanine quadruplexes: Magnetic relaxation dispersion studies of [d(G 3 T 4 G 3 )] 2 and [d(G 4 T 4 G 4 )] 2 . (lu.se)
  • It contains descriptions and evaluations of toxicological studies and epidemiological investigations and provides conclusions, where possible, on the relevance of toxicity and toxicokinetic data to public health. (cdc.gov)
  • It was observed that water orientational relaxation slowed down as the hydration level of lipids was reduced, in agreement with the recent experimental study. (bvsalud.org)
  • On the basis of these results, we hypothesized that excitotoxicity results from inhibition of synthesis rather than from increased degradation of phospholipids. (jneurosci.org)
  • The first method involves accentuating prolonged coagulation by reducing the amount of phospholipid, as is done in the tissue thromboplastin inhibition (TTI) test and the dilute aPTT test. (medscape.com)
  • The purpose of this open-label study was to investigate the effect of a curcumin-phospholipid lecithin formulation (Meriva®) on visual acuity and optical coherence tomography (OCT) retinal thickness in patients with chronic diabetic macular edema. (europeanreview.org)
  • Detection of Vulnerable Plaque With Intravascular Imaging According to this commentary, a new study conclusively demonstrates that optical coherence tomography as well as other noninvasive imaging modalities are capable of detecting vulnerable plaque. (medscape.com)
  • Among subjects with normal lung function, phospholipid levels were elevated in current smokers , in comparison to no effect of smoking on these lipids at abnormal lung function. (bvsalud.org)
  • Novel cyclopropane fatty acids from the phospholipids of the Caribbean sponge Pseudospongosorites suberitoides Lipids , 42(6), 519-524. (usp.br)
  • She has established a project of her own, working on large scale studies of proteins and pathways and networks of cellular lipids in biological systems. (cdc.gov)
  • They study how certain proteins and lipids (fats) in blood samples may indicate a level of risk for heart disease. (cdc.gov)
  • Screening with 2 or more phospholipid-dependent coagulation tests and demonstrating prolongation of at least one. (medscape.com)
  • PBPK models essentially represent a systems biology approach to the study of ADME and are increasingly finding use in screening-level as well as quantitative risk assessments to reduce the uncertainties associated with interspecies, route-to-route, and high-dose to low-dose extrapolations of tissue dose of chemicals [21-24]. (cdc.gov)
  • A study of the L α → H II interconversion in two unsaturated phosphatidylethanolamines (1-palmitoyl-2-oleoyl- (POPE) and 1,2-dielaidoyl- (DEPE)) shows a substantial increase in both gg and eg conformers near temperatures leading to the inverted micellar state in each instance, with smaller percentage increases in (kink + gtg) states. (researchwithrutgers.com)
  • Gut Microbiome in Cardiovascular Disease and Heart Failure A new study investigates the relevance of imidazole propionate, a gut microbial metabolite, to cardiovascular disease and heart failure. (medscape.com)
  • Rosemary Cornell , a professor of molecular biology and biochemistry at Simon Fraser University in Canada, studies the enzyme CTP:phosphocholine cytidylyltransferase, or CCT. (asbmb.org)
  • A series of CH 2 wagging modes in the 1320-1370-cm -1 region of alkane and phospholipid IR spectra characteristic of nonplanar conformers has been used for quantitative evaluation of conformational states in disordered (phospholipid L α and H II and alkane liquid) phases. (researchwithrutgers.com)
  • If a prolonged aPTT or aPTT-LA is demonstrated, the patient's plasma is then subjected to another phospholipid dependent coagulation assay of a different principle. (medscape.com)
  • [ 5 ] Other phospholipid-dependent coagulation tests include the Kaolin clotting test (KCT) and the dilute prothrombin time, both of which are not recommended by the ISTH due to poor reproducibility and reagent variability. (medscape.com)
  • In this study, we have substituted serine-43 by cysteine in the recombinant citrate synthase from a moderately thermophilic Archaeon Thermoplasma acidophilum, for site-specific attachment of labels and have investigated the effects of this mutation on the biochemical properties and thermal stability of the enzyme. (metu.edu.tr)
  • Participants who received Nutiani Phospholipids supplementation experienced significant reductions in stress levels compared to those in the placebo group. (fonterra.com)
  • The findings underscore the significant impact of broad-spectrum phospholipid supplementation in reducing stress levels and offer hope for anxiety alleviation. (fonterra.com)
  • After correction for the different body weights of mouse strains, phospholipid levels in BAL fluid of cftrm1HGU/m1HGU mice were increased by 64 (52 to 76)%, 60 (39 to 89)%, 72 (45 to 113)%, and 92 (49 to 163)%, respectively, compared with controls. (bmj.com)
  • The points in the figures showing no-observed-adverse-effect levels (NOAELs) or lowest- observed-adverse-effect levels (LOAELs) reflect the actual doses (levels of exposure) used in the studies. (cdc.gov)
  • Our results, albeit preliminary, suggest that a curcumin-phospholipid formulation (Meriva®), administered as Norflo® tablets, may be feasible in the improvement of visual acuity and reduction of macular edema in patients with diabetic retinopathy. (europeanreview.org)
  • Sudden Cardiac Death Among Adolescents in the United Kingdom This study investigated various etiologies of sudden cardiac death and their association with physical activity in a large cohort of adolescents, both athletes and non-athletes. (medscape.com)
  • Statin Use and Skin Cancer Risk: A Prospective Cohort Study. (who.int)
  • 1989. Toxicology studies of a chemical mixture of 26 groundwater contaminants. (cdc.gov)
  • Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. (nih.gov)
  • The vitamin E derivative with side chain modification (TC6OAc) has been shown to possess anticancer activity in our earlier in vivo studies. (metu.edu.tr)
  • The report combines extensive quantitative analysis and exhaustive qualitative analysis, ranges from a macro overview of the total market size, industry chain, and market dynamics to micro details of segment markets by type, application and region, and, as a result, provides a holistic view of, as well as a deep insight into the Phospholipids market covering all its essential aspects. (digitaljournal.com)
  • We explore here the assembly and adsorption response of a ternary bio oil-phospholipid-water system via dissipative particle dynamics (DPD) simulations. (aalto.fi)
  • Plasma phospholipid EPA, DHA and total fatty acids were measured by gas chromatography mass spectrometry and omega-3 fatty acid index calculated. (fabresearch.org)
  • We examined longitudinal associations of prepubertal dietary and plasma phospholipid FAs with several puberty timing traits in boys and girls. (cam.ac.uk)
  • In the Avon Longitudinal Study of Parents and Children, prepubertal fat intakes at 3-7.5 years and plasma phospholipid FAs at 7.5 years were measured. (cam.ac.uk)
  • Fatty acid profiles were measured in plasma triglyceride, cholesteryl and phospholipid fractions. (researchgate.net)
  • Only recently, one study ​ ​evaluated the relationship between the bitter taste of milk and the bitter content of the mothers' diets. (nutraingredients.com)
  • Phospholipid Phosphatase 4 promotes proliferation and tumorigenesis, and activates Ca(2+)-permeable Cationic Channel in lung carcinoma cells. (nih.gov)
  • This study characterized the potential effects of CeO2 exposure on lung toxicity. (cdc.gov)
  • These compounds have been used in intervention studies with breastfeeding mothers, such as investigations of bitter tasting caffeine, which can be transferred into milk. (nutraingredients.com)
  • Alcohol and Neural Network Activity A new study suggests a novel underlying mechanism for the protective effect of moderate alcohol consumption on cardiovascular health. (medscape.com)
  • The second and more sensitive method is to neutralize the inhibitor activity by increasing the amount of phospholipid, as is done in the platelet neutralization procedure (PNP) or the rabbit brain neutralization procedure (RBNP). (medscape.com)
  • A study on CognoLipid, a branded ingredient by Lipogen which contains phosphatidylserine (PS) and phosphatidic acid (PA), was one of ten studies to receive validation from a team of neurologists which conducted a systematic review of 1,380 studies on supplements' effects on cognitive function. (nutraceuticalsworld.com)
  • Uptake and incorporation of DEA into ceramide derivatives in human liver slices were also demonstrated in the present studies. (rti.org)
  • To confirm double bound location, N-acylpyrrolidide derivatives were used studying their mass spectra. (usp.br)
  • "We were particularly surprised by the latter, since piperine is supposed to significantly increase the bioavailability of curcumin according to the results of other studies," ​ comments Lang, who now heads the Biosystems Chemistry & Human Metabolism research group at the Leibniz Institute for Food Systems Biology (LSB). (nutraingredients.com)
  • The effect of ω3 fatty acids on the metabolism of the normal liver was studied using 31P NMR spectroscopy. (westminster.ac.uk)
  • Dr. Fuad's presentation at the ISSFAL Congress will provide further insights into the potential of broad-spectrum phospholipids sourced from MFGM to enhance psychological well-being, instilling hope for effective interventions. (fonterra.com)
  • The first study, according to the review authors, found that the PS and PA combination treatment was linked to significant improvements in Wechsler Memory Scale and List of Depression Symptoms Scale indices compared to placebo, in a population of functioning elderly participants. (nutraceuticalsworld.com)