Studies mice inbred icr. Medical search. Frequent questions

Common inbred strains include BALB/c, C3H, C57BL/6 and DBA. (uwm.edu)
Reproductive performance consisting of mean litter size, number of pups that wean (wean: born ratio) and mean reproductive index of three inbred mice strains, which are BALB/cMlac, C57BL/6Mlac and DBA/2Mlac, were investigated to provide some basic information on the breeding and maintaining of a foundation colony. (mahidol.ac.th)
Mice, Inbred C57BL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
This graph shows the total number of publications written about "Mice, Inbred C57BL" by people in this website by year, and whether "Mice, Inbred C57BL" was a major or minor topic of these publications. (uchicago.edu)
Below are the most recent publications written about "Mice, Inbred C57BL" by people in Profiles. (uchicago.edu)
In 1921, Littel obtained mice from Lathrop and named a strain of mice that was derived from the mating of female 57 and male 52 and that consistently exhibited black hair as C57BL. (nomura-siam.com)
C57BL/6J mice were introduced from the Jackson Laboratory to NIH and were maintained as C57BL6N. (nomura-siam.com)
C57BL/6N mice at F121 were introduced from NIH to the Central Institute for Experimental Animals in 1978, and then to CLEA Japan, Inc. at F121+25 in 1988. (nomura-siam.com)
In addition, C57BL/6J mice at F166 were introduced from the Jackson Laboratory to CLEA Japan, Inc., in 1989, at which time their production and supply was started. (nomura-siam.com)
C57BL/6NJcl mice grow slightly better than C57BL/6JJcl mice, but there are no marked differences between the two sublines. (nomura-siam.com)
C57BL/6 mouse splenocytes were stained with CD45R (B220) Monoclonal Antibody, FITC (Product # 11-0452-82) and 0.25 µg of Rat IgG2b kappa Isotype Control, Super Bright 600 (Product # 63-4031-82) (left) or 0.25 µg of CD3 Monoclonal Antibody, Super Bright 600 (right). (thermofisher.com)

Two inbred mouse strains (BALB/c and A/J) and one outbred strain (ICR) were subcutaneously injected with saline solutions containing penicillin G (1.25, 2.5 and 5 mg/mouse), D-penicillamine (0.5, 1 and 2 mg/mouse), or barbital (2 mg/mouse) into one hind footpad and saline only was injected into the contralateral footpad. (go.jp)
In longevity experiments, 16 female 11-mon-old BALB/c mice and both genders of 12-mon-old ICR mice were daily fed with BPSP supplemented diets at doses of 0, 0.1 and 0.5 g BPSP/kg bw for 750 and 762 days, respectively. (scirp.org)
This study was performed to produce reference data for eye toxicity tests and to investigate the ophthalmic diseases of 408 ICR mice and 119 BALB/c mice, which are commonly used as subjects in toxicity tests. (go.jp)
BALB/c mice, 31.9%) and the incidence gradually decreased with age. (go.jp)
BALB/c mice demonstrate pronounced autism-relevant behavioral phenotype characterized by low level of social relations, high levels of anxiety and aggression, increased brain weight, undeveloped corpus callosum, and lower serotonin concentration in the brain [7,12]. (epiphanyasd.com)
This work was designed to examine the effects of Afobazole on cognitive rigidity in BALB/c mice. (epiphanyasd.com)
Evidently, enhanced motor activity of Afobazole treated BALB/c mice reflected the anxiolytic effect of this drug, which stimulated exploratory behavior aimed at solving the novel task. (epiphanyasd.com)
The present study revealed the potency of Afobazole to promote retraining and reversal learning of BALB/c mice, which manifested in increased rate of adaptation to novel environment and more effective solution of the modified task. (epiphanyasd.com)

Collectively, these considerations led the large level mouse mutagenesis projects structured under the umbrella Aliskiren hemifumarate of the World Knockout Mouse Consortium (IKMC) to select M6-produced Sera cells as the parental lines in which to mutate all Aliskiren hemifumarate protein coding genes of Aliskiren hemifumarate mouse [5], [6]. (liveconscience.com)

There are over 400 documented inbred strains of mice. (uwm.edu)
Differences in hepatic fibrosis and granuloma size in several strains of mice infected with Schistosoma japonicum. (rsbmt.org.br)

In mice and rats, females require mating stimulation for the maintenance of pregnancy. (nature.com)
The production of female mice with pseudopregnancy induced using sonic vibration was as efficient as rats. (nature.com)
However, relatively little information is available on humane aspects of anesthesia and euthanasia in neonatal mice and rats. (bvsalud.org)
The study demonstrates that CO may be a potential alternative for preweanling mice and rats at PND6 or older but is not appropriate for neonates at PND5 or younger. (bvsalud.org)
The current study was designed based on existing literature regarding minimal exposure times for preweanling rats and mice euthanized with carbon dioxide. (bvsalud.org)
The study evaluated the minimal time that adult rats and mice must remain in 100% carbon dioxide for death to be irreversible on removal. (bvsalud.org)
Adult rats (14 stocks and strains) and mice (more than 40 stocks and strains) were euthanized using a 50% volume per minute displacement rate of carbon dioxide for 2 min. (bvsalud.org)
The experiment on 71 non-inbred white pregnant rats, 316 fetuses and placentas, 323 first progeny in experimental chronic impairment of uteroplacental circulation in females with pregnancy in the ploid period has found that decimetric waves (DW) in a weak heat dose (40 mW/cm2) prevents hypotrophy and disorders of fetal and placental development. (maxwellmagneticmeds.co.za)

After inbreeding for 20 generations, a surprisingly high incidence of hydronephrosis was encountered and we finally obtained a strain of mice with a very high incidence of severe hydronephrosis affected on both sides of kidney and in both sexes as the process of inbreeding has been increased. (mahidol.ac.th)
To perform a linkage analysis of the responsive gene, Mus musculus castaneus (CAST) (Jackson Laboratories, Bar Harbor, Maine) was chosen for the back-cross since it is relatively distant from the Jcl:ICR strain and there is abundant information about its microsatellite markers. (iiarjournals.org)
This strain is commonly used as genetic background for transgenic mouse models. (uchicago.edu)
Refractory to many tumors, this strain is also preferred model for studying role of genetic variations in development of diseases. (uchicago.edu)
This substrain is at least (a number>20 by definition) generations removed from the originating JAXR Mice strain and has NOT been re-infused with pedigreed stock from The Jackson Laboratory. (nomura-siam.com)
In a previous study, we have demonstrated that Lactobacillus plantarum TWK10 (TWK10), a probiotic strain isolated from Taiwanese pickled cabbage, improved muscle strength, exercise endurance, and overall body composition in healthy humans. (frontiersin.org)

One naturally occurring genetic defect in mice results in an animal with no hair that is called a nude. (uwm.edu)

The purpose of this study was to investigate the protective effects of Dunaliella salina ( D. salina ) on UVB radiation-induced corneal oxidative damage in male imprinting control region (ICR) mice. (molvis.org)
The studies demonstrate that D. salina exhibits potent protective effects on UVB radiation-induced corneal oxidative damage in mice, likely due to both the increase of antioxidant enzyme activity and the inhibition of lipid peroxidation. (molvis.org)

The most commonly used methods for catching and picking up mice are grasping the animal near the tip of the tail, between thumb and forefinger, or by grasping the tail near the base or the neck between the ends of a smooth tipped forceps. (uwm.edu)
Materials and Methods: In order to identify the genetic abnormality, the mouse was back-crossed to Mus musculus castaneus (CAST), and myosine 15 or myoXV on chromosome 11 was assumed to be the responsive gene. (iiarjournals.org)
Improved methods for the generation of germline transmitting chimeric mice from M6 Sera cell lines will make the IKMC and additional M6 Sera cell resources more accessible to the broader biomedical Aliskiren hemifumarate study community. (liveconscience.com)
Methods This retrospective, propensity-score matched (PSM) case-control study included 180 patients hospitalized with COVID-19 from 3 centers. (researchgate.net)

The short-term skin carcinogenesis bioassay using rasH2™ mice could represent a useful tool for the assessment of drug and chemical safety with cutaneous treatment. (taconic.com)
The ultra-short-term bioassay described in this report may represent a useful screening tool to predict skin carcinogenesis during the early stages of drug development, prior to more laborious and time-consuming regulatory studies. (taconic.com)

Phenotypes determination, genetic segregation test crosses and histological study of kidneys were also performed. (mahidol.ac.th)
Her thesis worked explored the genetic architecture of DDK syndrome and the genetic basis for embryonic lethality in mice. (wikipedia.org)
The ease of manipulating its genome has helped establish the mouse as the premier model organism for mammalian genetic studies. (biomedcentral.com)
Genetic-linked variation in susceptibility of mice to Schistosomiasis mansoni . (rsbmt.org.br)
The multifactorial nature of ASD precludes the use of its modern genetic models in the study of pharmacologic effects exerted on entire symptomatic complex of autism although they could relate functional correction of ASD with a certain gene. (epiphanyasd.com)

Previously, a low incidence of mild hydronephrosis was observed mostly in male mice and found only on the right kidney. (mahidol.ac.th)

C-BF also reduced LPS induced TNF-α expression through the NF-κB signaling pathway in mouse RAW 264.7 macrophages. (unboundmedicine.com)

Selective inbreeding of this mutant led us to the establishment of a colony of inbred hydronephrosis mice. (mahidol.ac.th)

Jacinta: Yes, and of course Darwin did all his studies on phenotypes, a term he would never have heard. (ussromantics.com)

These animals are used to study the function of the various genes. (uwm.edu)
They are used to study the diseases associated with defective genes. (uwm.edu)
Since regulation of imprinted genes was thought to be governed by the epigenetic modifications to the imprinting control region (ICR), Ideraabdullah explored whether there are regions outside the ICR that are important in the regulation of imprinted genes. (wikipedia.org)
The genes relevant to deafness have been identified from the analysis of models of spontaneous deaf mice and many genes from such mice have been reported. (iiarjournals.org)
Germline transmission breeding and subsequent backcrosses to C57BT/6 (M6) to generate congenic stresses delay practical studies and increase costs, while at the same time genes closely linked to the unique targeted locus remain from the unique Sera cell genome and may confound study results [4]. (liveconscience.com)

Although multiple developmental abnormalities in Dot1L-deficient mouse embryos have been studied, the biological function of H3K79 methylation in mammal oocytes remains unclear. (nel.edu)
Scholars@Duke publication: Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos. (duke.edu)
To determine the developmental expression pattern of this molecule, we performed in situ hybridization analysis on early mouse embryos. (duke.edu)
Genome-edited mice were also obtained using frozen-warmed pronuclear embryos with clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated system (Cas) nucleases introduced using the technique for animal knockout system by electroporation (TAKE) method, which were transferred to females with pseudopregnancy induced on the day of embryo transfer. (nature.com)
Aggregation of cleavage stage embryos with Sera cells [29] gives an accessible method for generating Sera cell chimeric mice. (liveconscience.com)

2000), but these studies are not considered here because of the difficulties of controlling for all potential lung carcinogens in the rubber industry. (who.int)

In recent years green fluorescent protein (GFP) from the bioluminescent jellyfish Aequoria Victoria has gained popularity in mouse transgenic and gene targeting regimes [ 1 ]. (biomedcentral.com)
The ECFP and EYFP-expressing transgenic ES cells and mice that we have generated provide sources of cells and tissues for combinatorial, double-tagged recombination experiments, chimeras or transplantations. (biomedcentral.com)
Since the ICH guidance on testing for carcinogenicity of pharmaceuticals was issued, medium-term carcinogenicity bioassays and 26-week short-term carcinogenicity studies using transgenic mice have been conducted as an alternative to a second traditional long-term (ie, 2-year) carcinogenicity study. (taconic.com)

Inbred strains are the result of at least 20 generations of brother-sister mating. (uwm.edu)

This study established a low incidence hydronephrosis Wistar rat (Mlac:WR) colony at the National Laboratory Animal Center, Mahidol University, Thailand. (mahidol.ac.th)
despite this, few studies have examined the incidence, prevalence, or exposure-associated rates of infection or have considered infection-specific interventions recommended to maintain worker safety. (liverpool.ac.uk)
These mice are known for their low incidence of mammary cancers and their resistance to exogenous tumor induction and are widely used for studies on cancer and immunology and for those in the field of toxicity and microbiology. (nomura-siam.com)

In exhaled breath condensate (EBC) and urine of 22 office employees occupationally exposed to TiO2 during their visit in the production workshops for average 14±9 min/day a panel of biomarkers of nucleic acids and proteins oxidation was studied, specifically 8-hydroxy-2-deoxyguanosine (8-OHdG), 8-hydroxyguanosine (8-OHG), 5-hydroxymethyl uracil (5-OHMeU), o-tyrosine (o-Tyr), 3-chlorotyrosine (3-ClTyr), and 3-nitrotyrosine (3-NOTyr). (nel.edu)
The current study successfully profiled the venom proteome of authenticated N. sputatrix, and showed that the venom is made up of approximately 64% three-finger toxins (including neurotoxins and cytotoxins) and 31% phospholipases A2 by total venom proteins. (afpm.org.my)
the primary amino acid sequences of the proteins coded by marburg and ebola-zaire filoviruses were studied by computer programs to search for putative proteolytic cleavages which yield nonapeptides with motifs of binding to known hla class i haplotypes. (liverpool.ac.uk)
2018) Individual odour signatures that mice learn are shaped by involatile major urinary proteins (MUPs). (phbuffers.org)
Individual recognition in mice mediated by major urinary proteins. (phbuffers.org)
The study of the 3D structure of proteins supports the investigation of their functions and represents an initial step towards protein based drug design. (scitevents.org)

These IC activity patterns were analyzed quantitatively using voxel-based statistical comparisons between groups of mice with or without sound stimulation. (uea.ac.uk)

We have previously demonstrated the utility and developmental neutrality of enhanced green fluorescent protein (EGFP) in embryonic stem (ES) cells and mice [ 2 ]. (biomedcentral.com)
In this study we have used embryonic stem (ES) cell-mediated transgenesis to test the enhanced cyan fluorescent protein (ECFP) and enhanced yellow fluorescent protein (EYFP), two mutant and spectrally distinct color variants of wild type (wt) GFP. (biomedcentral.com)
Genetically modified mouse strains derived from embryonic stem (ES) cells have become essential tools for functional genomics and biomedical research. (liveconscience.com)

The mutagenicity of 4-phenyl-1, 3-dithia-2-thioxo-cycLopent-4-ene (DT827B) was examined in reverse mutation tests using Salmonella tryphimurium and Escherichia coli, in the chromosomal aberration test with Chinese hamster ovary (CHO) cells, and in the micronucleus test using mice bone-marrow. (go.jp)
Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: Observation of a positive response. (cdc.gov)

Mice were fed p.o. with saline or OH-BBN (0.05%, w/v) in drinking water for 6 weeks or with silymarin or silibinin (200 mg/kg body weight for both) starting 1 week before OH-BBN exposure for 51 weeks. (nih.gov)

We synthesized the hyperforin analog Hyp13, which shows similar binding to TRPC6 and recapitulates TRPC6-dependent anxiolytic and antidepressant effects in mice . (afpm.org.my)
We therefore investigated the effects of acetazolamide, furosemide, hydrochlorothiazide, and amiloride, known to preferentially inhibit sodium reabsorption at different segments of the nephron, on hypoxia-induced EPO formation in mice. (uni-regensburg.de)
The present study characterized hydrosalpinx epithelial cell culture and examined the effects of its conditioned medium (CM) on sperm motility, acrosome reaction and embryo development. (hku.hk)
Effects of Depilatory Cream Formulation and Contact Time on Mouse Skin. (uchicago.edu)
which concluded that skin promotion effects could be detected within only eight weeks in the rasH2™ mice , and that the concentration of 4 μg TPA once weekly was sufficient as a positive control. (taconic.com)

These mice have deficiencies in their immune systems and thereby prove valuable in the study of immune diseases and cancer. (uwm.edu)
The use of ET has recently increased owing to the production of many types of genetically modified laboratory animals for the study of human diseases 12 , 13 . (nature.com)

Manganese-enhanced MRI (MEMRI) has been developed to image brain activity in small animals, including normal and genetically modified mice. (uea.ac.uk)

Herein, we evaluated chemoprevention of urinary bladder cancer by natural chemopreventive agents, silymarin and silibinin, in a preclinical animal (ICR mouse) model of bladder cancer induced by tobacco smoke carcinogen N-butyl-N-(4-hydroxybutyl) nitrosamine (OH-BBN). (nih.gov)

This study investigated whether C-BF pretreatment could protect the intestinal barrier against dysfunction in a mouse model of endotoxemia, induced by intraperitoneal injection of LPS (10mg/kg). (unboundmedicine.com)

for some studies, in particular immunology [2] and neurobiology [3]. (liveconscience.com)

Some silymarin- or silibinin-treated mice developed no urothelial lesions in spite of OH-BBN exposure. (nih.gov)
Estimates of occupational exposure to carbon black have been incorporated into the UK and German cohort mortality studies of carbon black production workers but not in the United States study of carbon black production workers. (who.int)

Inbred plants, like inbred animals, don't fare well, at least over time-a phenomenon that's now known as inbreeding depression. (ussromantics.com)
based on sufficient evidence in experimental animals and inadequate evidence from epidemiological studies. (who.int)

The mouse was bred with the mutant deaf mouse and offspring (the first generation, F1) mice were obtained. (iiarjournals.org)
F1 mice were then back-crossed to the original mutant deaf mice and hybrid F2 generation mice were obtained. (iiarjournals.org)

It is of merit to demonstrate that peanut kernels as a potent producer could be bio-elicited to biosynthesize a broad spectrum of bioactive stilbenes to prepare BPSP which is effective to extend mouse longevity as science-evidenced by the two long-term animal experiments. (scirp.org)
We demonstrate that TRPC6 deficiency in mice not only results in anxious and depressive behavior, but also reduces excitability of hippocampal CA1 pyramidal neurons and dentate gyrus granule cells. (afpm.org.my)

Young mice ( pups) should be grasped by the cupping the hands around the whole body or by grasping the skin across the shoulder blades with a forceps. (uwm.edu)
This study was designed to assess the effectiveness of carbon monoxide (CO) as an alternative euthanasia agent for mouse and rat pups on postnatal days (PND) 0 to 12. (bvsalud.org)

She mutated different regions within the ICR for H19/IGF2 and this caused a loss of repression of the imprinted gene, yet the methylation patterns at the imprinted gene's ICR and promoter region did not change. (wikipedia.org)
Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes. (nel.edu)
Dot1L and H3K79 methylation play important roles in meiosis progression and are supposed to be associated with chromosome deacetylation of mouse oocytes. (nel.edu)
Wang X, Gao W, Ma X, Wang X, Song C, Huang X, Liu H. Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes. (nel.edu)

Sperm motility and acrosome reaction were determined using computer-aided sperm analysis and acrobead assay respectively and embryo development by mouse embryo development assay. (hku.hk)

In conclusion of the three mutagenicity studies, DT827B was considered to cause no mutagenicity under the conditions used in the present experiments except the increase in polyploidy, which probably is due to a toxic effect of the compound. (go.jp)

Following this finding, Ideraabdullah generated and characterized a mouse model of Beckwith-Wiedemann Syndrome (BWS), a disorder caused by aberrations in gene imprinting. (wikipedia.org)
Background: We have established a mouse model of spontaneous deafness by sib-inbreeding over 10 years. (iiarjournals.org)
Genetically manipulated mice, often incorporating gene-based reporters, are frequently being used to model and understand mammalian development and disease processes. (biomedcentral.com)
In this study, we used mice lacking the SR-A (SRKO) to investigate the role of SR-A in acquired immunity using a viable bacillus Calmette Guérin (BCG) infection model. (ox.ac.uk)
Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. (uchicago.edu)

2014) Comparative study of the molecular variation between 'central' and 'peripheral' MUPs and significance for behavioural signalling. (phbuffers.org)

Her first work in the lab helped to elucidate the sequence diversity of 20 inbred mouse strains based on substitutions, insertions, and deletions. (wikipedia.org)

We therefore wished to investigate the feasibility of non-invasive multiple reporter imaging in mice, and as a first step we wanted to ascertain whether we could establish viable and fertile mice with widespread expression of GFP variant reporters. (biomedcentral.com)

In this study, estrus females were stimulated on the day of embryo transfer. (nature.com)
Reduced acrosome reaction and poor mouse embryo development were also observed in hydrosalpinx CM but not in NFT CM and hTF. (hku.hk)

Differences in hepatic fibrosis in ICR, C3H, and C57 BL/6 mice infected with Schistosoma manson . (rsbmt.org.br)

Pharmacological study of the new mucolytic drug N-guanyl-cysteine. (curehunter.com)
In relation to the idea to use magnetic nanopartic les in development of new delivery systems suitable for targeted drug administration, the toxicological profile of five types of magnetic fluids was assessed in mice. (nel.edu)

however, in spite of the obvious advantages of Aliskiren hemifumarate the inbred background few targeted mutations have been published compared to the widely used 129 Sera cell lines [1]. (liveconscience.com)

In addition, we show that an antibody which blocks TNF-alpha activity reduces LPS-induced mortality in these mice. (ox.ac.uk)
Neumeyer-Gromen A, Razum O, Kersten N, Seidler A, Zeeb H. Diesel motor emissions and lung cancer mortality--results of the second follow-up of a cohort study in potash miners. (who.int)

The clinical significance of these findings is unclear and more studies are needed. (nel.edu)
Her findings were the first to suggest that mechanisms outside the ICR are necessary to mediate the fully repressed state of an imprinted gene. (wikipedia.org)

For comparison, we studied the expression of N-cadherin and found that the expressions of these two cadherins were differential, and complementary in some tissues. (duke.edu)
We found that TWK10 not only enhanced muscle strength in young mice, but also prevented the aging-related loss of muscle strength in aged mice, which was accompanied by elevated muscle glycogen levels. (frontiersin.org)

The mouse was designated as kuru 2 and has been previously reported in this Journal. (iiarjournals.org)

The neutralizing antibody response against vesicular stomatitis virus (VSV) was studied to analyze conditions necessary for induction of mature B cells. (ox.ac.uk)
Here, we report the use of a MEMRI-based statistical parametric mapping method to analyze sound-evoked activity in the mouse auditory midbrain, the inferior colliculus (IC). (uea.ac.uk)
Objective To evaluate the risk of bias and reporting quality of animal experimental studies on the use of acupuncture for hypertension, and analyze the deficiencies in experimental design, implementation, and reporting, to reduce the risk of bias and improve the reporting quality of animal studies. (alljournal.net.cn)

Experimental studies using nanoscale TiO2 have documented lung injury, inflammation, oxidative stress, and genotoxicity. (nel.edu)
This study may provide an experimental basis for in vivo intestinal absorption of medicines containing euscaphic acid. (alljournal.net.cn)

Based on the resultant survival curves and average lifespans of both mouse models, basal diets supplemented with BPSP are effective to extend mouse longevity by a dose dependent manner. (scirp.org)
Mice were treated with low or high dose C-BF before treatment with LPS, and samples were collected 5h after LPS treatment. (unboundmedicine.com)

Acute toxicity of magnetic nanopartic les in mice. (nel.edu)
Gut microbiota modulates bleomycin-induced acute lung injury response in mice. (uchicago.edu)

After BCG infection, SRKO mice are able to recruit Mphi to sites of granuloma formation where they become activated and restrict BCG replication. (ox.ac.uk)

In Dot1L deficient, accompanying with BubR1 (MAD3/Bub1b) remains on the chromosome, the mouse oocytes was blocked in metaphase of meiosis I. The histone deacetylation was also incomplete in Dot1L-deficient mouse oocytes. (nel.edu)

The distinction among the spitting cobras was however unclear prior to the revision of cobra systematics in the mid-90's, and results of some earlier studies are now questionable as to which species was implicated back then. (afpm.org.my)
The most recent paper provided results validating the original paper, concluding that "after initiation with 7,12-dimethylbenz[a]anthracene (DMBA), the promoting potential of 12-O-tetradecanoylphorbol-13-acetate (TPA) on skin tumor development can be detected by an ultra-short-term skin carcinogenicity bioassay using Tg-rasH2 mice and that the detection of skin tumor promotion and carcinogenicity was feasible in only eight weeks. (taconic.com)

Studies performed in mice indicated that the peripheral pathogenicity of LBV had been underestimated in previous studies. (cdc.gov)

The investment in training should be outweighed by the benefits observed with more reliable behavioral and physiological responses in the mice. (uwm.edu)
In experiments, the models of idiopathic ASD are based on inbred mice selected by behavioral phenotype. (epiphanyasd.com)

In this study, the effect of TWK10 on the progression of age-related impairments was investigated in mice. (frontiersin.org)

More laboratory mice are used in research every year than any other animal species. (uwm.edu)

She studied the molecular mechanisms of genomic imprinting, where gene expression is dependent on whether the gene was inherited from the mother or the father. (wikipedia.org)

The down regulation of Dot1l in mouse oocytes was conducted using siRNA injection technique. (nel.edu)

Background: Recent studies have reported the negative impact of hydrosalpinx on IVF outcome. (hku.hk)

Ideraabdullah is the principal investigator of the Ideraabdullah Lab which studies the mechanisms by which the epigenome is modified by the environment during development. (wikipedia.org)
This represents a significant advance in the development of MEMRI for quantitative and unbiased analysis of brain function in the deep brain nuclei of mice. (uea.ac.uk)
In Japan, the 2-stage skin carcinogenicity bioassay with CD-1 (ICR) mice is recognized as a tool for the assessment of topical carcinogenicity in the development of dermal liniments by the Pharmaceuticals and Medical Devices Agency (PMDA) of Japan, and in the United States, more than 75% of mouse carcinogenicity studies are now conducted using Tg-rasH2 mice. (taconic.com)

This study examined the application of this method for the induction of pseudopregnancy in mice. (nature.com)
This study demonstrated that induction of pseudopregnancy by sonic vibration was also possible in mice. (nature.com)

Anatomy1

Organisms2

Diseases5

Chemicals and Drugs8

Phenomena and Processes4

Health Care1

C57BL11

BALB8

Mutagenesis1

Strains of mice2

Rats8

Strain6

Nude1

Corneal2

Methods4

Carcinogenesis2

Genetic5

Male1

Macrophages1

Selective1

Phenotypes1

Genes5

Embryos5

20001

Transgenic3

Generations1

Incidence3

Proteins6

Comparisons1

Embryonic3

Bone-marrow2

Saline1

Effects5

Diseases2

Genetically modified1

Urinary1

Intraperitoneal1

Immunology1

Exposure2

Animals2

Mutant2

Demonstrate2

Pups2

Methylation4

Assay1

Conclusion1

Model5

Variation1

Sequence1

Investigate1

Embryo2

Differences1

Drug2

Spite1

Mortality2

Findings2

Found2

Previously1

Analyze3

Experimental2

Dose2

Acute2

Granuloma1

Chromosome1

Results2

Peripheral1

Behavioral2

Progression1

Animal1

Molecular1

Regulation1

Background1

Development3

Induction2