• The study used a retrospective cohort design. (cdc.gov)
  • We conducted a large, cohort study to assess the impact of ETS exposure on birth weight whilst adjusting for the many factors known to influence this. (nih.gov)
  • Retrospective study using interview data from parents of 18,297 children born in 2000/2001 and living in the UK 9 months afterwards (the Millennium Cohort Survey). (nih.gov)
  • We explored the association between prenatal exposure to SHS and neurodevelopment at 24 months of age considering genetic polymorphism and breastfeeding in 720 mothers and their offspring enrolled in the Korean multicenter birth cohort study (Mothers and Children Environmental Health, MOCEH). (biomedcentral.com)
  • CHILD researchers have deeply assessed indoor and outdoor environmental exposures for 3,217 Canadian babies-an unprecedented accomplishment for any birth cohort. (childstudy.ca)
  • Association between gas stove use and childhood asthma in the Canadian CHILD Cohort Study. (childstudy.ca)
  • Gestational age at birth and body size from infancy through adolescence: An individual participant data meta-analysis on 253,810 singletons in 16 birth cohort studies. (childstudy.ca)
  • We aimed to investigate whether maternal exposure to residential transportation noise, before and during pregnancy, was associated with GDM in a nationwide cohort. (lu.se)
  • This study involved a multiethnic cohort of 50,045 participants in Iran. (medicalnewstoday.com)
  • Methods and analysis We are conducting a community-based birth cohort study to examine interactions between gut microbiome conditions and enteric infections, and how environmental conditions affect the development of the gut microbiome. (bmj.com)
  • A birth cohort design allows us to examine prospectively how environmental factors impact the gut microbiome over the critical first 2 years of life. (bmj.com)
  • The study is performed on a subset of term placentae from mothers enrolled within the ENVIR ON AGE birth cohort study and on preterm placentae from spontaneous terminated pregnancies. (nature.com)
  • Beyond the environmental pathways and drivers of mercury exposure, how a bird takes in, processes, and excretes contaminants influences exposure and potential effects. (usgs.gov)
  • When updating its air contaminants standard in 1989, OSHA decreased this limit to 0.005 ppm (0.036 mg/m3) as an 8-hour time-weighted average (TWA) and 0.02 ppm (0.14 mg/m3) as a short-term exposure limit. (cdc.gov)
  • Emerging evidence suggests that environmental contaminants--including pesticides--may play an important role in the pathogenesis of diabetes. (sciencedaily.com)
  • The study on PFAS and obesity suggests that these chemicals and other mostly invisible environmental contaminants could have a role in the obesity epidemic plaguing the country. (naturalnews.com)
  • Due to the significant increases in weight regain linked to PFAS exposure, "future dietary trials may wisely consider blood concentrations of these contaminants to obtain more precise results," concluded the researchers. (naturalnews.com)
  • What can a clinician do to improve recognition of disease related to current or past exposures? (cdc.gov)
  • However, few studies have considered associations between direct estimates of long-term past exposures and brain MRI findings indicative of neurodegeneration or cerebrovascular disease. (rti.org)
  • This study was not designed to assess possible association between thimerosal and autism. (cdc.gov)
  • Exposure research looks for ways to improve methods, measurements and models to assess and predict exposures of humans and ecosystems to harmful environmental stressors. (sutterhealth.org)
  • Systematic reviews play a similar role today as literature reviews in the past in that both attempt to provide an overview of the literature on a particular topic, either within a discipline (e.g., epidemiology) or across disciplines, and typically assess the evidence for causality for the association between exposure and disease. (nih.gov)
  • In this context, digitalization is a key driver for the development of new ways to collect, assess, and monitor environmental stressors with wearable sensor technologies which help to explore the urban human exposome, which is defined as the total of people's exposure to environmental factors throughout their lifetime [ 3 ]. (springer.com)
  • The size of the study and the rigour with which we assess environmental exposure will increase our capacity to detect associations between environmental factors and health outcomes. (childstudy.ca)
  • We will use longitudinal regression models to assess the correlation between environmental conditions and gut microbiome diversity and presence of specific taxa, controlling for factors that are known to be associated with the gut microbiome, such as diet. (bmj.com)
  • A study was conducted in Madrid to assess the feasibility of implementing a surveillance system of exposure among the general population to specific environmental pollutants, using bio-markers. (isciii.es)
  • Multiple biologic substrates were collected from each participant in order to assess the most suitable samples for an environmental surveillance system. (isciii.es)
  • In particular, branch researchers have been actively involved in assessing associations of environmental exposures including endocrine-disrupting chemicals in relation to a spectrum of reproductive outcomes in both men and women. (nih.gov)
  • Endocrine disrupting chemicals (EDCs) are man-made chemicals, common in everyday population exposure, and have been associated with unfavorable health effects and development. (diva-portal.org)
  • Excess risks of hypospadias associated with occupational exposures to phthalates and hair spray suggest that anti-androgenic endocrine disrupting chemicals may play a role in hypospadias. (ecochildsplay.com)
  • Environmental stressors can include chemical pollutants, microbes and pathogens, physical agents such as land use, and processes such as alteration of wildlife habitat. (sutterhealth.org)
  • In the natural environment they can be subjected simultaneously to a mixture of environmental stresses (hypoxia, starvation) and to pollutants. (port.ac.uk)
  • Environmental exposures can be external factors such as sunlight, chemical pollutants, diet, and social interactions, or internal factors, such as stress or metabolism. (nih.gov)
  • PFAS are common environmental pollutants dubbed "forever chemicals. (naturalnews.com)
  • A weighted kernel machine regression approach to environmental pollutants and infertility. (nih.gov)
  • In Spain environmental surveillance has mainly relied on measures of selected pollutants in air, water, food and soil. (isciii.es)
  • Early Thimerosal exposure and neuropsychological outcomes at 7 to 10 years. (cdc.gov)
  • In 2007, CDC published the Infant and Environmental Exposures to Thimerosal and Neuropsychological Outcomes at Ages 7 to 10 Years study, which investigated possible associations between prenatal and early childhood exposure to thimerosal-containing vaccines and/or immunoglobulins and deficits in neuropsychological functioning. (cdc.gov)
  • These documents allow for a more complete presentation of methods and results than was possible within the space constraints of the scientific article, "Early thimerosal exposure and neuropsychological outcomes at 7 to 10 years" by Thompson et al. (cdc.gov)
  • It is well known that SHS exposure brings about almost the same adverse health outcomes as active smoking [ 3 ]. (biomedcentral.com)
  • In the "Discussion" section, we synthesized the outcomes of the case studies and provide take-home messages for the reader. (springer.com)
  • Future research is needed to evaluate the effect of low-level arsenic exposure on specific cardiovascular outcomes. (nih.gov)
  • They are now performing additional analyses of the data and doing a further meta-analysis of pesticide exposure in relation to the other outcomes, including neurological outcomes and several cancers. (sciencedaily.com)
  • 5 6 Some strong evidence supports that disparities in birth outcomes are largely attributable to environmental, as opposed to genetic variation. (bmj.com)
  • The main weakness of the WalletHub study, like most studies of its type, is that it focuses on outcomes, a highly dubious measure of racial fairness. (marylandreporter.com)
  • To coincide with the Joint Annual Meeting of the International Society of Exposure Science and the International Society for Environmental Epidemiology ( ISES-ISEE 2018 ), Environmental Health has published this collection to highlight top accessed articles in line with the conference theme: Addressing complex local and global issues in environmental exposure and epidemiology - Selected articles for ISES-ISEE 2018. (biomedcentral.com)
  • To elucidate the epidemiology of murine typhus, which is infrequently reported in Japan, we conducted a cross-sectional study involving 2,382 residents of rickettsiosis-endemic areas in Honshu Island during August-November 2020. (cdc.gov)
  • BBB investigators have been actively collaborating with investigators from the Epidemiology Branch as well as academic institutions in studies focused on environmental influences on human fecundity and fertility. (nih.gov)
  • Meng Wang, Ph.D., an assistant professor of epidemiology and environmental health at the University at Buffalo School of Public Health and Health Professions in New York, is the lead author of the study. (medicalnewstoday.com)
  • Lead author Youssef Oulhote, assistant professor of biostatistics and epidemiology at UMass Amherst's School of Public Health and Health Sciences, told EHN this apparent protective effect of folic acid was the "most important finding" of the study. (ehn.org)
  • The study was conducted by researchers from Imperial College London, University College Cork (Ireland), and Center for Research in Environmental Epidemiology (Spain) and is the first to show a significant link between hairspray and hypospadias, which is one of the most common birth defects of the male genitalia. (ecochildsplay.com)
  • Measure of cotinine in hair, blood, and urine permits the assessment of SHS exposure or active smoking. (biomedcentral.com)
  • Ecological Momentary Assessment with REDCap: Methods, Feasibility, and User Behaviour in a Parent and Child Study. (childstudy.ca)
  • Comparative assessment of environmental risk and risk of resistance selection in human use of ivermectin, metronidazole, lymecycline and azelaic acid in Sweden. (janusinfo.se)
  • The Children's Environmental Exposure Research Study (or CHEERS) was a study conducted by the United States Environmental Protection Agency designed to examine how children may be exposed to pesticides and other chemicals used in U.S. households, such as phthalates, brominated flame retardants, and perfluorinated compounds (PFOS, PFOA, PFNA, and others). (wikipedia.org)
  • Preterm birth is a significant public health concern and exposure to phthalates has been shown to be associated with an increased odds of preterm birth. (biomedcentral.com)
  • However, only a handful of small studies have looked at whether phthalates affect human breast cancer risk and none have measured phthalate metabolites before a cancer diagnosis. (eurekalert.org)
  • Further, by measuring excreted products rather than phthalates themselves, the researchers say they can be confident that they are measuring personal exposure rather than laboratory or other contamination. (eurekalert.org)
  • Many people assume that any kind of environmental exposure to phthalates is bad even if the scientific evidence is unclear, Reeves points out, "but with this study we hope to provide not more uncertainty, but instead either reassurance or solid evidence of cause for concern. (eurekalert.org)
  • The new study does not prove that phthalates- widely used in certain plastics, personal care products, pharmaceuticals, food packaging, and medical devices- cause autism, however, it adds to a growing body of evidence that prenatal exposure to certain chemicals may impair social development and suggests folic acid may protect against some of these potential impacts. (ehn.org)
  • The study was also limited in that it looked at mostly white, higher income mothers and children, the researchers only tested the women once for phthalates, and the tests to tease out autistic traits in the children are not always accurate and don't represent an autism diagnosis. (ehn.org)
  • Meta-analyses of studies investigating the impact of maternal environmental tobacco smoke (ETS) on birth weight have not produced robust findings. (nih.gov)
  • Evidence synthesis (or evidence integration) is widely used to summarize findings of epidemiologic studies of environmental and occupational exposures. (nih.gov)
  • Such syntheses are part of systematic reviews of observational epidemiologic study findings. (nih.gov)
  • These findings indicate that the effect of low-level arsenic exposure on blood pressure is nonlinear and may be more pronounced in persons with lower intake of nutrients related to arsenic metabolism and cardiovascular health. (nih.gov)
  • Our findings suggest that chronic fluoride exposure from drinking water is associated with alterations of serum SHBG and ABP concentrations in local male farmers and that the effect of fluoride exposure on ABP levels vary depending on ESR? (fluoridealert.org)
  • OBJECTIVE: Our objective was to quantify the association between brain MRI findings and PM exposures approximately 5 to 20 y prior to MRI in the Atherosclerosis Risk in Communities (ARIC) study. (rti.org)
  • BACKGROUND: Few studies have investigated whether road traffic noise is associated with gestational diabetes mellitus (GDM), and have yielded inconsistent findings. (lu.se)
  • Perfluoroalkyl chemicals, menstrual cycle length, and fecundity: findings from a prospective pregnancy study. (nih.gov)
  • Sen. Cory McCray, D-Baltimore City, said he is not familiar with the study but believes its "findings are encouraging. (marylandreporter.com)
  • Those are among the findings of a new Stanford study published Sept. 22 in Environmental Science & Technology that focuses on a type of particle pollution known as PM2.5, which can lodge deep in our lungs and even get into our bloodstream. (stanford.edu)
  • Critics, however, contended that the state of knowledge about pesticide exposure risks to infants and children while imprecise, suggests that residential pesticide exposure poses developmental risks to infants and children. (wikipedia.org)
  • World Health Organization (WHO) has recently reported that environmental risks including SHS take lives of 1.7 million children under 5 years of age every year [ 2 ]. (biomedcentral.com)
  • Harmful exposure to these environmental risks could begin in the mother's womb and affect fetal development. (biomedcentral.com)
  • This complexity and information gap can make it difficult to understand or predict where methylmercury exposure poses the greatest health risks. (usgs.gov)
  • Relative Contributions of Four Exposure Pathways to Influenza Infection Risk" calculates the risks involved with each kind of exposure in a setting where a person attends a bed-ridden individual ill with influenza. (sciencedaily.com)
  • Although this is the first study to find such specific effects of perchlorate contamination, the chemical has been linked to health risks by the Centers for Disease Control and Prevention for some time now. (medicaldaily.com)
  • Compared to no ante natal tobacco smoke exposure, domestic ETS lowered infants' adjusted mean birth weights by 36 g (95% CI, 5 g to 67 g) and this effect showed a dose-response relationship. (nih.gov)
  • To study exposure to environmental tobacco smoke during the first year of life, 220 infants attending the outpatient paediatric clinic of the University of Jordan for routine visits with their mothers were recruited to the study. (who.int)
  • Recommendations are made to protect this vulnerable population from tobacco smoke exposure. (who.int)
  • Infant and early childhood exposure to environmental tobacco smoke is well recognized as a health hazard [1]. (who.int)
  • Compared to adults, infants are more susceptible to the damaging effects of environmental tobacco smoke. (who.int)
  • Because of this hyperresponsiveness, attacks can be triggered by irritants other than allergens, such as physical activity, respiratory infections, or exposure to tobacco smoke, in people with allergic asthma. (medlineplus.gov)
  • Air pollution exposures contributed a significant burden of cardiovascular disease, similar to tobacco smoke…The study demonstrates that environmental risk factors are present and evaluable in rural, low-resource settings. (medicalnewstoday.com)
  • A major epidemiological study on environmental tobacco smoke has been completed and revealed a significant dose-response relationship between passive smoking (at home or at the workplace) and lung cancer. (who.int)
  • ¾ To better understand and asses students' attitudes, knowledge and behaviors related to tobacco use and its health impact, including: cessation, environmental tobacco smoke (ETS), media and advertising, minors access and school curriculum. (who.int)
  • ¾ Measures to ensure that Non -smokers receive effective protection, to which they are entitled, from involuntary exposure to tobacco smoke. (who.int)
  • The overall aim of this thesis was to evaluate the associations between prenatal exposure to EDC mixtures and nutrition respectively, with birthweight, growth and body composition in early- and mid-childhood, and to determine if these associations differed by sex. (diva-portal.org)
  • UK prevalences of domestic ETS exposure and maternal smoking in pregnancy remain high and ETS exposure lowers infants' birth weights. (nih.gov)
  • The consequences of prolonged exposure in close proximity to parental smoking are exacerbated by infants' immature immune and pulmonary systems [2], small body size and higher rates of ventilation [3]. (who.int)
  • Therefore, more attention should be paid to pregnant women and infants who are susceptible to SHS exposure. (biomedcentral.com)
  • Environmental toxicants in breast milk of Norwegian mothers and gut bacteria composition and metabolites in their infants at 1 month. (nih.gov)
  • This study aimed to perform an in-depth holistic exploration of the environmental, socio-cultural, economic and institutional context surrounding infants to develop an integrated understanding of enteric infection drivers in rural tribal Banswara, in Rajasthan State, India. (biomedcentral.com)
  • Infants aged 5 to 24 months were seen to have constant exposures to dirt via mouthing of soil, soiled hands, soiled objects and food. (biomedcentral.com)
  • Several unsafe behaviours failing to interrupt infants' exposures to pathogens were captured, but caregivers reported a lack of self-efficacy skills to separate children from faecal exposures due to the rural farming environments where they lived. (biomedcentral.com)
  • Although effects of prenatal exposure to SHS on early neurodevelopment vary among studies, they remain significant issues. (biomedcentral.com)
  • Results suggest that higher prenatal exposure to EDC mixtures were associated with lower birthweight, and slower weight gain in early childhood, including a later peak growth velocity among girls. (diva-portal.org)
  • In conclusion, prenatal exposure to both EDC mixtures and nutrition suggests to have an influence on birthweight, and children´s growth. (diva-portal.org)
  • The study was due to be completed in two years, researchers would follow the progress of 60 young children whose parents sprayed pesticides frequently. (wikipedia.org)
  • Also, because the researchers will have three stored urine samples, from baseline, Year 1 and Year 3 for analysis, they will be able to address variation in phthalate exposure. (eurekalert.org)
  • In this study, the researchers performed a systematic review and meta-analysis of observational studies that assessed the association between exposure to pesticides and diabetes. (sciencedaily.com)
  • Researchers Dr. Mark Nicas of the University of California Berkeley's School of Public Health, and Dr. Rachael M. Jones of the University of Illinois Chicago's School of Public Health, used sophisticated modeling and examined available research to show infection rates in four pathways of exposure dealing with direct skin contact and inhalation of cough particles. (sciencedaily.com)
  • Newborn babies and foetuses of women in their third trimester, who are exposed to high levels of air pollution, are at a higher risk of being shorter for their age or stunted in later life, a study conducted by researchers at the Indian Institute of Technology, Delhi, has revealed. (hindustantimes.com)
  • For the study, the researchers investigated a frustrating problem that is common among many adults: gaining pounds after successful weight loss despite sticking to a healthy diet. (naturalnews.com)
  • The researchers also found that higher background PFAS exposures had an even greater effect on weight gain than going on a diet. (naturalnews.com)
  • In an earlier study, Grandjean and his fellow researchers analyzed weight loss and weight gain in volunteers from Massachusetts and Louisiana. (naturalnews.com)
  • The researchers believe that this is an area worth studying. (naturalnews.com)
  • Additionally, BBB researchers are also focused on studying the application of the exposome research paradigm for understanding environmental influences on human fecundity and fertility impairments. (nih.gov)
  • Researchers are still working to discover what environmental factors pose the most risk to heart health and how people can reduce their risk. (medicalnewstoday.com)
  • The researchers looked at the risk association between specific environmental exposures and mortality. (medicalnewstoday.com)
  • The study provided extensive data due to the number of participants included and the number of risk factors researchers examined. (medicalnewstoday.com)
  • Because of this collection method, researchers could not account for previous exposures, changes over time, or acute exposures. (medicalnewstoday.com)
  • Researchers from Boston University School of Medicine and Cardiff University combined efforts to study how high levels of perchlorate in mothers affect their offspring, according to a recent press release . (medicaldaily.com)
  • In their study, researchers followed 487 mother-child pairs from women with underactive thyroid glands. (medicaldaily.com)
  • It should include the use of classical considerations for judging causality in human studies, as well as triangulation and integration of animal and mechanistic data. (nih.gov)
  • Reeves says, "This study, where the samples were given many years before any sign of disease appeared, will give us much stronger evidence in terms of causality than studies using another design. (eurekalert.org)
  • This study suggests that SW may play a role in development of frailty and this warrants further investigation. (lww.com)
  • CONCLUSION: In conclusion, this nationwide study suggests that railway noise but not road traffic noise might be associated with GDM. (lu.se)
  • New research suggests that chronic exposure to ambient ozone may raise the risk of atherosclerosis and harm arterial health. (medicalnewstoday.com)
  • The model] suggests that there is an association between long-term exposure to ozone and progression of atherosclerosis," he goes on to report. (medicalnewstoday.com)
  • A new study suggests that high amounts of a chemical commonly found in nearly everything we consume may be limiting the intelligence of children before they are even born. (medicaldaily.com)
  • A small study suggests that environmental PFAS exposure may raise the risk for thyroid cancer. (medscape.com)
  • on Echo Child's Play in 2008, Another Reason We Can't Trust the FDA, Melamine…, New Study Suggests Link Between Hairspray Exposure and Genital Birth Defect, How Safe is Your Child's Playground? (ecochildsplay.com)
  • According to a study published in the journal Obesity , perfluoroalkyl and polyfluoroalkyl substances (PFAS) are linked to obesity and weight gain after following a healthy diet . (naturalnews.com)
  • The participants ranking in the top third of PFAS exposure regained an average of 10 pounds more than the participants in the bottom third of the exposure curve. (naturalnews.com)
  • Study author Philippe Grandjean, who is a research professor at the University of Rhode Island , warned that PFAS exposure increase a person's obesity risk and that it is not just a matter of lacking physical activity and eating a poor diet . (naturalnews.com)
  • The results showed that PFAS exposure was linked to weight gain after the initial loss via dieting. (naturalnews.com)
  • The case with previous occupational exposure to mercury (case 28) was excluded from the regression analyses (see text). (biomedcentral.com)
  • This Alert summarizes seven case reports of disease and deaths following occupational exposure to diisocyanates. (cdc.gov)
  • Occupational exposure normally occurs during the production and use of isocyanates-particularly during the mixing and foaming processes in the polyurethane foam industry. (cdc.gov)
  • Occupational exposure standards for isocyanates are based on respiratory irritation and sensitization and carcinogenesis. (cdc.gov)
  • Exposure research also provides the foundation for the development of approaches to reduce these exposures and safeguard humans and the environment. (sutterhealth.org)
  • Methylmercury exposure poses a perceived health risk to humans and wildlife globally. (usgs.gov)
  • However, exposure to methylmercury alone does not determine the health risk to humans or wildlife-numerous pathways and processes in the environment and within an organism can alter its toxicity. (usgs.gov)
  • With growing technology and industrialization, humans are constantly exposed to various environmental toxicants through air, water, food chain, and various other sources. (nih.gov)
  • More importantly, the latter was one of the first studies that provided evidence of particle translocation in humans. (nature.com)
  • I will in this paper discuss how Lidman here gives a secular reading to the Christian theme of original sin, and how this reading (in line with Lidman's intent), can be used to make sense of our complex moral relation to the environmental consequences of modernity. (lu.se)
  • Flight attendants are an understudied occupational group, despite undergoing a wide range of adverse job-related exposures, including to known carcinogens. (biomedcentral.com)
  • A correct diagnosis may help stop exposure and might prevent disease in others by avoiding exposure [ATSDR 2015]. (cdc.gov)
  • First, one must be suspicious and think about the possibility of environmental and occupational factors of disease. (cdc.gov)
  • The National Institute for Occupational Safety and Health (NIOSH) requests assistance in preventing asthma, other respiratory disease, and death from diisocyanate exposure. (cdc.gov)
  • The study will also evaluate whether associations between phthalate metabolite levels and breast cancer vary by disease characteristics such as hormone receptor status and personal factors including age, postmenopausal hormone therapy use and body mass index. (eurekalert.org)
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
  • Research in this field aims to determine the types, levels, and combinations of exposures people experience and how those exposures affect human health and disease over a lifetime. (nih.gov)
  • Scientists also seek to understand how these exposures affect our chance of developing disease. (nih.gov)
  • Understanding the human exposome is important because common illnesses, such as cancer, cardiovascular disease, and diabetes, may result from multiple and varied environmental exposures over time, as well as interactions between those exposures and your genes. (nih.gov)
  • CONCLUSIONS: Long-term past PM exposure in was not associated with markers of cerebrovascular disease. (rti.org)
  • Asthma is the most common chronic childhood disease and many cases may be preventable," says Takaro, a physician-scientist trained in occupational and environmental medicine, public health and toxicology. (childstudy.ca)
  • In 2017, 12.5% of all the deaths and 8.1% of all the life years lost due to premature death or disability could be attributed to air pollution, according to the state-level disease burden study published in The Lancet in 2018. (hindustantimes.com)
  • Of the top ten causes of environmental death , ischemic heart disease ranks number one. (medicalnewstoday.com)
  • Wang and colleagues clinically followed 6,619 adults, who were 45-84 years old and who did not have cardiovascular disease or any other conditions at the start of the study. (medicalnewstoday.com)
  • To the authors' knowledge, this is the first epidemiological study to examine the link between ozone exposure and "subclinical vascular disease" - that is, injuries that damage the artery walls before a heart attack or a stroke occurs. (medicalnewstoday.com)
  • The association between exposure to secondhand smoke (SHS) during pregnancy and a child's neurodevelopment has not been established yet. (biomedcentral.com)
  • The association between exposure to any pesticide and all types of diabetes was examined. (sciencedaily.com)
  • We quantified urine cotinine concentrations in mothers once from 12th to 20th gestational weeks and excluded those whose urine cotinine levels exceeded 42.7 ng/ml to represent SHS exposure in early pregnancy. (biomedcentral.com)
  • NIOSH further recognized the carcinogenic potential of TDI and its isomers and recommended that exposures be reduced to the lowest feasible concentrations [NIOSH 1989]. (cdc.gov)
  • A number of epidemiological studies have reported that chronic exposure to high concentrations of fluoride not only causes dental and skeletal fluorosis but additionally affects serum levels of reproductive hormones. (fluoridealert.org)
  • With estimates that half the population of the United States could be infected with the 2009 H1N1 flu virus this fall and winter, a new study examines four flu exposure pathways and quantifies the risk posed by each pathway, which, the analysis found, varies based on changes in viral concentrations. (sciencedaily.com)
  • Thus, all four exposure pathways should be addressed when someone is sick, as it is difficult to know which one poses the most risk as virus concentrations change. (sciencedaily.com)
  • The study used population data from the Demographic and Health Survey 2015-16 and compared it to satellite-based district level PM 2.5 concentrations during the birth month of the children. (hindustantimes.com)
  • Detectable saliva cotinine levels in 8/20 mothers of neonates (1-2 days old) suggested in utero exposure. (who.int)
  • Fetal development is a critical window of exposure-related susceptibility because the etiology of diseases in adulthood may have a fetal origin and may be attributed to adverse effects of in utero environmental exposures. (nature.com)
  • The EPA also received $2 million of the proposed 9 million budget for the CHEERS study from the American Chemistry Council, a lobbying group representing 135 chemical companies in exchange for measuring levels of common household chemicals such as flame, retardants, and ingredients in plastic products along with pesticides. (wikipedia.org)
  • Reeves and colleagues will study phthalate metabolites, which are products found in urine samples after the chemicals have passed through the body. (eurekalert.org)
  • Early life is an important period for growth and development and therefore, sensitive to environmental exposures, such as chemicals and nutrition. (diva-portal.org)
  • Used with drugs and chemicals for experimental human and animal studies of their ill effects. (bvsalud.org)
  • Methylmercury is a chemical that is often found in some fish and exposure primarily occurs by eating fish. (cdc.gov)
  • Some of the team's most recent contributions provide information on when and where methylmercury exposure occurs, pathways of contaminant bioaccumulation, and whether the exposure affects bird health. (usgs.gov)
  • However, initial and subsequent well-child visits offer opportunities to provide parents and caregivers with educational materials on preventing exposures and actions to take if an exposure occurs. (cdc.gov)
  • Therefore, environmental pollution occurs more frequently, longer, and more intensively with citizens suffering from its negative health impacts [ 94 ]. (springer.com)
  • The following technical reports are extended versions of the manuscript and describe all of the various analyses conducted in this study. (cdc.gov)
  • Stratified analyses showed neither significant nor suggestive trends when case-control comparisons for silicosis were examined by level of dust exposure or smoking. (bmj.com)
  • Increasingly, risk of bias tools are used to evaluate epidemiologic studies as part of evidence synthesis (evidence integration), often involving meta-analyses. (nih.gov)
  • Subjectivity (value-based judgment) is inevitably present in the assessments of the quality of the individual studies (including whether they suffer from biases) and in the decisions to include or exclude studies in evidence syntheses and meta-analyses. (nih.gov)
  • Longitudinal secondary data analyses were performed using Canadian Longitudinal Study on Aging. (lww.com)
  • Separate analyses for studies that looked only at type 2 diabetes (T2D) participants were performed. (sciencedaily.com)
  • In almost all of the studies analyses, pesticide exposure was determined by blood or urine biomarker analysis, one of the most accurate methods. (sciencedaily.com)
  • Subgroup analyses did not reveal any differences in the risk estimates based on the type of studies or the measurement of the exposure. (sciencedaily.com)
  • Additionally, human biomonitoring data from Canada and Alaska indicate exposure to cadmium is low except for individuals who smoke cigarettes. (cdc.gov)
  • Human biomonitoring studies are needed in Alaska to determine actual cadmium exposure in populations with a lifelong history of moose liver and kidney consumption. (cdc.gov)
  • The current Occupational Safety and Health Administration (OSHA) permissible exposure limit (PEL) for TDI is 0.02 part per million parts of air (0.02 ppm), or 0.14 milligram per cubic meter of air (0.14 mg/m3) as a ceiling limit [29 CFR* 1910.1000]. (cdc.gov)
  • Breathing zone lead exposures in shop-A and shop- B were below 50 micrograms per cubic meter (microg/m3), the OSHA permissible exposure limit (PEL). (cdc.gov)
  • BACKGROUND: Increasing evidence links higher particulate matter (PM) air pollution exposure to late-life cognitive impairment. (rti.org)
  • Inaccuracies in data collection regarding socioeconomic status, as well as using participants' fuel use and ventilation levels to examine air pollution exposure indirectly may have affected the results. (medicalnewstoday.com)
  • Funding sources: Funding for the Canadian Longitudinal Study on Aging (CLSA) is provided by the Government of Canada through the Canadian Institutes of Health Research (CIHR) under grant reference: LSA 94473 and the Canada Foundation for Innovation, as well as the following provinces, Newfoundland, Nova Scotia, Quebec, Ontario, Manitoba, Alberta, and British Columbia. (lww.com)
  • Disclaimer: The opinions expressed in this article are those of the authors and do not reflect the views of the Canadian Longitudinal Study on Aging. (lww.com)
  • The authors performed a cross-sectional analysis to evaluate the association between arsenic exposure from drinking water and blood pressure using baseline data of 10,910 participants in the Health Effects of Arsenic Longitudinal Study in Bangladesh (October 2000-May 2002). (nih.gov)
  • Endocrine disruptors exposure during pregnancy and longitudinal fetal growth in the NICHD Fetal Growth Studies: singletons. (nih.gov)
  • Data from mother-child pairs in the Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA) study was analyzed, including 26 EDCs in prenatal urine and serum samples, children's anthropometric and body composition measures up to seven years of age, and sociodemographic data from questionnaires and registers. (diva-portal.org)
  • Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. (biomedcentral.com)
  • Glyphosate (GLY) is the most heavily used herbicide worldwide but the extent of exposure in human pregnancy remains unknown. (biomedcentral.com)
  • In addition, some studies in recent years looking at mid to late pregnancy have not found links between mothers' phthalate levels and autism traits in their children later in life. (ehn.org)
  • Furthermore, the placental BC load is positively associated with mothers' residential BC exposure during pregnancy (0.63-2.42 µg per m 3 ). (nature.com)
  • Women exposed to hairspray in the workplace in their first trimester of their pregnancy have more than double the risk of having a son with the genital birth defect hypospadias, according to a new study published in the journal Environmental Health Perspectives . (ecochildsplay.com)
  • It is encouraging that our study showed that taking folic acid supplements in pregnancy may reduce the risk of a child being born with the condition. (ecochildsplay.com)
  • The U.S. Geological Survey's (USGS) Ecologically-Driven Exposure Pathways Team , with partners from academia, industry, and tribal, State, and Federal agencies, provides tools to facilitate understanding of mercury and other toxicant exposure and effects on birds and other wildlife. (usgs.gov)
  • In order to provide an improved in vitro model with which to investigate human diseases, such as cancer that may be promoted by toxicant exposure, we have characterized a newly developed cell line derived from the renal proximal tubule epithelial cells (RPTEC) of a healthy human male donor. (tulane.edu)
  • image: Epidemiologist Katherine Reeves at UMass Amherst is leading the largest study to date investigating a possible relationship between phthalate exposure and breast cancer risk. (eurekalert.org)
  • We do not know if these subtle effects associated with prenatal phthalate exposure will last after the preschool period," said child development specialist and study co-author Gina Muckle, professor at Université Laval and Quebec-CHU Research Center in Quebec City, Canada, in a statement. (ehn.org)
  • A significant increase in the expression of NRF2 antioxidant pathway genes after co-exposure was observed. (tulane.edu)
  • Studies suggest that more than 100 genes may be associated with allergic asthma, but each seems to be a factor in only one or a few populations. (medlineplus.gov)
  • This is one of the largest studies in the world to look in depth at how genes and the environment interact to impact the development of allergies, asthma and other chronic diseases. (childstudy.ca)
  • These studies will help scientists better understand the initiating events that may promote carcinogenesis in normal, healthy human cells. (tulane.edu)
  • Scientists seek to better understand how various types of exposures are transported across land, air, and water and, upon contact with people, transformed within our bodies. (nih.gov)
  • Scientists in many areas of study seek to understand what increases people's risk for death. (medicalnewstoday.com)
  • Increasingly, however, scientists are looking at environmental exposures as a potential culprit. (ehn.org)
  • IARC scientists coordinated several studies on the adverse health effect of exposure to styrene, man-made vitreous fibres, organic mercury compounds and substances affecting workers in the paper, wood, leather and asphalt industry and in biological research laboratories. (who.int)
  • The exposome is the sum of all environmental exposures and our body's response to those exposures across the lifespan. (nih.gov)
  • High exposure to the chemical affects the body's ability to absorb iodine, the building block of thyroid hormones. (medicaldaily.com)
  • This may indicate that the association between long-term exposure to ozone and cardiovascular mortality that has been observed in some studies is due to arterial injury and acceleration of atherosclerosis," comments Wang. (medicalnewstoday.com)
  • WASH factors as currently defined do not capture the overall exposure factors to faecal pathogens through the numerous infection transmission pathways. (biomedcentral.com)
  • A recent study published in PLoS ONE examined the associated risk between certain environmental exposures and mortality, including cardiovascular mortality. (medicalnewstoday.com)
  • This NIOSH recommended exposure limit (REL) was intended to prevent acute and chronic irritation and sensitization of workers but not to prevent responses in workers who are already sensitized. (cdc.gov)
  • Many environmental stressors are harmful to people's health. (springer.com)
  • EPA recruiting information for CHEERS claimed that participation in the study presented "no risk" to the subjects or their families. (wikipedia.org)
  • Community studies in Europe, United States, Australia and elsewhere in the world have suggested that smoking by mothers and other household members results in increased risk of chronic childhood otitis media, coughs, wheezing, bronchitis, asthma and sudden infant death syndrome (SIDS) [1,4-6]. (who.int)
  • We review the strengths and limitations of risk of bias assessments, in particular, for reviews of observational studies of environmental exposures, and we also comment more generally on methods of evidence synthesis. (nih.gov)
  • Rather than a checklist approach when evaluating individual studies using risk of bias tools, we call for identifying and quantifying possible biases, their direction, and their impacts on parameter estimates. (nih.gov)
  • As is recognized in many guidelines, evidence synthesis requires a broader approach than simply evaluating risk of bias in individual studies followed by synthesis of studies judged unbiased, or with studies given more weight if judged less biased. (nih.gov)
  • Boxes 4 and 5 of this figure (evaluate evidence, integrate evidence) depict where risk of bias assessments come into play via evaluations of individual studies and evidence synthesis across studies, and they are the subject of this paper. (nih.gov)
  • Therefore, SHS exposure should be considered a modifiable risk factor for delayed neurodevelopment and cognitive impairment in children. (biomedcentral.com)
  • A meta-analysis of 21 studies shows that exposure to pesticides is associated with increased risk of developing diabetes by 61 percent, with different types of pesticides showing varying levels of risk. (sciencedaily.com)
  • A meta-analysis of 21 studies presented at this year's annual meeting the European Association for the Study of Diabetes (EASD) shows that exposure to pesticides is associated with increased risk of developing diabetes by 61%, with different types of pesticides showing varying levels of risk. (sciencedaily.com)
  • In the 12 studies analysing only type 2 diabetes, the increased risk was 64% for those exposed to pesticides. (sciencedaily.com)
  • The authors conclude: "This systematic review supports the hypothesis that exposure to various types of pesticides increases the risk of diabetes. (sciencedaily.com)
  • The study appears in the September issue of the peer-reviewed journal Risk Analysis, published by the Society for Risk Analysis. (sciencedaily.com)
  • In examining ways of reducing the risk of preventing infections through each pathway, the study supports general advisories to cover coughs, wash hands frequently, and disinfect surfaces. (sciencedaily.com)
  • Environmental factors play a role in health, with research finding that people living in certain areas have a higher risk for health problems and mortality. (medicalnewstoday.com)
  • Multiple factors such as air pollution and fuel-burning methods can impact cardiovascular and all-cause mortality risk at varying degrees, according to a new study. (medicalnewstoday.com)
  • The study notes the importance of looking at and addressing environmental risk factors related to cardiovascular health. (medicalnewstoday.com)
  • It is likely that reducing risk and improving these environmental factors will involve the work of multiple people and groups. (medicalnewstoday.com)
  • Specifically, the study found an association between chronic ozone exposure and an "increased rate of carotid wall thickness progression and risk of new plaque formation. (medicalnewstoday.com)
  • So, our study aimed to examine whether the low level of fluoride exposure was associated with the risk of dental fluorosis. (fluoridealert.org)
  • Low level of water or plasma fluoride exposure was associated with increased the risk of dental fluorosis. (fluoridealert.org)
  • Therefore, our study aimed to examine whether the low level of fluoride exposure (measured in blood plasma and household tap water) was associated with the risk of dental fluorosis based on data of the National Health and Nutrition Examination Survey (NHANES) 2015-2016. (fluoridealert.org)
  • Background Earlier studies have demonstrated that smoking and genetic risk factors interact in providing an increased risk of rheumatoid arthritis (RA). (bmj.com)
  • Smoking is the most established environmental risk factor for developing rheumatoid arthritis (RA). (bmj.com)
  • We have therefore used our population-based study, the Epidemiological Investigation of Rheumatoid Arthritis (EIRA), to estimate the relative risk of RA conferred by different amounts of smoking in the context of different HLA-DRB1 genotypes, and to estimate the excess fraction (EF) of RA cases attributed to smoking. (bmj.com)
  • The risk of effects of human use of ivermectin is also low, given an expected contribution to exposure in aquatic environments at subnanogram levels, and a majority of efficacy studies that show significantly higher levels of efficacy. (janusinfo.se)
  • Since there is (at least) a study that reports effects at 1 pg/L, however, one can not completely rule out risk. (janusinfo.se)
  • Multicentre case-control studies clearly demonstrated a cervical cancer risk associated with infection with a variety of human papillomaviruses (HPV) other than types 16 and 18. (who.int)
  • The CHILD Study is helping us to gain a better understanding of the link between environment and health, which may help us to intervene early in life to prevent asthma from occurring. (childstudy.ca)
  • Exposure and toxicity of environmental mercury to birds can be enhanced or lessened due to the available sources and forms of mercury and other species dependent factors such as life stage, migratory patterns, foraging and nesting behaviors, transfer of mercury from mothers to eggs, and sex. (usgs.gov)
  • We found that people are being exposed to more days with wildfire smoke and more extreme days with high levels of fine particulate matter from smoke," said lead study author Marissa Childs , who worked on the research as a PhD student in Stanford's Emmett Interdisciplinary Program in Environment and Resources (E-IPER). (stanford.edu)
  • Trends of SHBG and ABP levels in male farmers: Influences of environmental fluoride exposure and ESR alpha gene polymorphisms. (fluoridealert.org)
  • However, possible interaction between fluoride exposure and estrogen receptor alpha (ESR? (fluoridealert.org)
  • Here, we conducted a cross-sectional study including 348 male farmers with different fluoride exposure levels from drinking water in Henan province of China to explore effects of fluoride exposure and ESR? (fluoridealert.org)
  • Furthermore, fluoride exposure and single nucleotide polymorphisms at the XbaI and rs3798577 loci of the ESR? (fluoridealert.org)
  • Associations of low level of fluoride exposure with dental fluorosis among U.S. children and adolescents, NHANES 2015-2016. (fluoridealert.org)
  • There is a growing awareness of the need to record personal environmental conditions ("the human exposome") and to study options and implications of adaptive and protective behavior of individuals. (springer.com)
  • How diabetes develops is considered to be an interplay between genetic and environmental factors. (sciencedaily.com)
  • The study of the exposome is called exposomics. (nih.gov)
  • Due to rapid advances in -omics technology in the last two decades, the concept of the exposome represents a wide view of many environmental factors that act upon our biology. (nih.gov)
  • To investigate the association between shift work exposure and frailty. (lww.com)
  • In this study Mytilus edulis was used to investigate the effects of two pesticides, atrazine and lindane, which have different modes of action but produce similar changes in behaviour (depression of ventilation and feeding) in the mussels, and can cause starvation and mild hypoxia. (port.ac.uk)
  • In recent years, studies were conducted to investigate whether (nano)particles can pass the placental barrier. (nature.com)
  • We give an overview of the study designs, highlight and compare limitations as well as results, and present the results of a keyword analysis. (springer.com)
  • Next, we present the characteristics of the selected case studies such as study design, equipment and parameters, and limitations as well as a qualitative keyword analysis. (springer.com)
  • The chemical is perchlorate, found in many foods and drinking water supplies, and the detailed study revealed women with higher amounts of it in their body gave birth to children with below-average IQs. (medicaldaily.com)
  • The argument is based on the fact that the study had an observational, rather than experimental design. (wikipedia.org)
  • Observational studies should not be considered inherently biased vs. a hypothetical RCT. (nih.gov)