• Methods and analysis In this prospective, randomised, controlled clinical study, one eye of each patient was injected with OVD1 (Viscopack14) or OVD2 (DuoVisc) during phacoemulsification and intraocular lens implantation. (bmj.com)
  • This article will introduce an important research development to provide an evidence-based approach to current treatment methods and practices for young patients. (lww.com)
  • Methods The CCQ, St George's Respiratory Questionnaire (SGRQ), Chronic Respiratory Questionnaire (CRQ) and COPD Assessment Test (CAT) were measured in 261 patients with COPD before and after outpatient PR. (bmj.com)
  • Methods This was a single-blind, single-arm study over 3-4 weeks from September 2005 to November 2006. (bmj.com)
  • Methods-- We implemented a pragmatic cluster randomized controlled trial to test the effectiveness of an automated interactive voice response tool designed to provide physicians with real-time patient-reported data about responses to newly prescribed diabetic peripheral neuropathy medicines. (cdc.gov)
  • According to the investigators, the results suggested that alternative training methods should be sought to improve exercise capacity in patients with Kugelberg Welander SMA. (medscape.com)
  • We often see patients who are older in life come to us with a spectrum of co-morbidities, like diabetes and osteoarthritis, as a result of their obesity. (disabled-world.com)
  • We often see patients who are older in life come to us with a spectrum of co-morbidities, like diabetes and osteoarthritis, as a result of their obesity," said Fayez Quereshy, MD, MBA, FRCSC, staff surgeon at the University Health Network in Toronto and a senior author on the study. (disabled-world.com)
  • The use of nutritional ERPs may enhance short-term and long-term recovery and mitigate frailty progression while improving patient-reported outcomes. (bmj.com)
  • Data gathered from the PROTein to Enhance outComes of (pre)frail paTients undergoing Cardiac Surgery Study will be published in peer-reviewed journals and presented at national and international conferences. (bmj.com)
  • Additionally, the study will provide information on long-term adherence, changes in motor symptoms, cognitive functions and patient-reported outcomes after the rehabilitation program. (frontiersin.org)
  • The long-term outcomes of this study are to assess long-term consequences on mortality and quality of life at 180 and 360 days. (biomedcentral.com)
  • Immunonutrition represents a promising approach also in patients with NSCLC, but evidence on its efficacy on clinical outcomes during immunotherapy is still inconclusive. (biomedcentral.com)
  • Initial data analysis showed potential for impact in the right direction for some outcomes measured including glycated haemoglobin, quality of life and patient satisfaction with information about medicines. (bmj.com)
  • Preoperative magnetic resonance imaging, upright radiographs, surgical reports and patient records will be evaluated, and clinical and functional outcomes will be measured. (springer.com)
  • This study aims to compare radiological and functional outcomes of the DELTA Xtend® Reverse Shoulder System Lateralized Glenosphere Line Extension (intervention group) with the Standard DELTA Xtend® Reverse Shoulder System (control group). (lu.se)
  • The secondary outcomes are inferior scapular notching, patient-reported and functional outcomes (Oxford shoulder score, Constant-Murley score and pain), side effects and complications, changes in bone mineral density and economy. (lu.se)
  • The post hoc analysis showed that the clinically meaningful improvements in the generalized myasthenia gravis symptoms were maintained over time for the cohort across rozanolixizumab cycles, while individual patients move through the consecutive treatment cycles, rozanolixizumab had an acceptable safety profile that was maintained across repeated treatments cycles. (medscape.com)
  • Under intense stress patients with BPD may exhibit transient dissociative or paranoid symptoms. (wikipedia.org)
  • 14 A similar training programme improved symptoms and physiological findings in an open study of patients with the "effort syndrome. (bmj.com)
  • Background -Several reports indicate that physical activity can reduce the severity of symptoms in depressed patients. (bmj.com)
  • For selected patients with moderate to severe major depression, aerobic exercise may result in a substantial improvement in symptoms in a short time. (bmj.com)
  • The minimum duration of therapy considered was one week, and studies had to report either a global assessment of cure or improvement in symptoms, or cure of or improvement in abdominal pain, after treatment. (bmj.com)
  • Results 12 studies compared fibre with placebo or no treatment in 591 patients (relative risk of persistent symptoms 0.87, 95% confidence interval 0.76 to 1.00). (bmj.com)
  • Various antispasmodics were studied, but otilonium (four trials, 435 patients, relative risk of persistent symptoms 0.55, 0.31 to 0.97) and hyoscine (three trials, 426 patients, 0.63, 0.51 to 0.78) showed consistent evidence of efficacy. (bmj.com)
  • Irritable bowel syndrome is a chronic relapsing and remitting condition, 8 9 and a significant proportion of patients will consult their general practitioner with symptoms. (bmj.com)
  • The first step, in order to provide suitable and accessible primary healthcare, is to assess the extent of physical symptoms and unmet healthcare needs within the OST population, which, to this point, has been sparsely studied. (hindawi.com)
  • Patients in OST have a high degree of physical symptoms and a high degree of unmet healthcare needs. (hindawi.com)
  • Patients in OST carry a heavy burden of physical symptoms and unmet healthcare needs, potentially due to societal barriers. (hindawi.com)
  • Using an image-guided minimally invasive procedure that takes less than 10 minutes, patients could alleviate symptoms of parosmia, a condition characterized by a distorted sense of smell. (medicaldaily.com)
  • Patients were those presenting to their family practitioner with troublesome upper gastrointestinal symptoms (n=308). (bmj.com)
  • Gastroenterologists and family practitioners acquire this skill predominantly by experience in practice, using analysis of symptom patterns and assessment of how much the reflux-induced symptoms are troubling the patient. (bmj.com)
  • Recent systematic reviews and meta-analyses 1-3 show that patients who participate in cardiac rehabilitation have significant reductions in mortality and morbidity including improvements in exercise tolerance, symptoms, blood lipid profiles, blood pressure and psychosocial wellbeing. (rrh.org.au)
  • Severe diseases, including those with severe symptoms, untreated inflammatory and infectious processes, due to which the patient cannot receive treatment in accordance with the study protocol. (who.int)
  • Patients assigned to physicians in the intervention group receive three brief interactive calls every 2 months after a medication is prescribed to alleviate diabetic peripheral neuropathy symptoms. (cdc.gov)
  • These calls provide patients with the opportunity to report on symptoms, side effects, self-titration of medication dose and overall satisfaction with treatment. (cdc.gov)
  • Patients were assessed a second time either before or after discontinuation of the antidepressant, and followed up for six months to assess relapse. (nature.com)
  • 29 patients went on to relapse and 38 remained well. (nature.com)
  • Further seed-based analyses, however, failed to reveal differences in functional connectivity between patients and controls, between relapsers and non-relapsers before discontinuation and changes due to discontinuation independent of relapse. (nature.com)
  • Indeed, confrontation and humiliation actually increase relapse and dropout. (time.com)
  • The new efficacy analysis focused on 110 patients who underwent two or more consecutive symptom-driven treatment cycles. (medscape.com)
  • By using a valid, pretested, semistructured tool, we interviewed patients about various costs incurred by themselves, their families, or both, from the time they became a presumptive MDR TB patient until they underwent pretreatment evaluation at PMDT. (cdc.gov)
  • Committed to delivering an outstanding patient-volunteer experience, the 40-FTE strong team at Firstsource underwent rigorous training and put advanced quality mentoring in place. (firstsource.com)
  • Patients aged ≥ 18 years who underwent implantation of a megaendoprosthesis due to periprosthetic or primary fractures of the lower extremity between January 2010 and February 2023 were identified from the authors' hospital information system. (bvsalud.org)
  • One hundred seventy-eight patients with OA of the knee were enrolled in a 2-year prospective, controlled, double-blind multicenter trial and were randomly assigned to receive acetaminophen (ACT) or naproxen (NPX) treatment. (nih.gov)
  • Among these patients, radiographic progression was similar in the 2 treatment groups. (nih.gov)
  • PHOENIX - Open-label extension studies of two neonatal Fc receptor-blocking antibodies showed good safety and efficacy in patients with myasthenia gravis (MG). The two drugs, rozanolixizumab (Rystiggo, UCB) and efgartigimod PH20 (Vyvgart, Argenx SE), received Food and Drug Administration approval in June 2023 and December 2021, respectively, for the treatment of MG. (medscape.com)
  • A safety analysis focused on 188 patients who received at least one cycle of treatment. (medscape.com)
  • TFP has been validated as an efficacious treatment for borderline personality disorder (BPD), though too few studies have been conducted to allow firm conclusions about its value. (wikipedia.org)
  • Four patients receiving exercise and three receiving flexibility treatment dropped out before completion. (bmj.com)
  • 16 of 29 patients rated themselves as better after completing exercise treatment compared with eight of 30 patients who completed flexibility treatment. (bmj.com)
  • 12 of 22 patients who crossed over to exercise after flexibility treatment rated themselves as better after completing exercise treatment. (bmj.com)
  • 32 of 47 patients rated themselves as better three months after completing supervised exercise treatment. (bmj.com)
  • 35 of 47 patients rated themselves as better one year after completing supervised exercise treatment. (bmj.com)
  • Virtual reality (VR) has emerged as a promising treatment approach in rehabilitation for patients with multiple sclerosis (MS) due to its potential to increase patient motivation and rehabilitation adherence. (frontiersin.org)
  • Cytotoxic chemotherapy drugs have become the main treatment in recent decades, especially in patients with NSCLC without EGFR, ALK, and ROS gene mutations. (biomedcentral.com)
  • This study explores the combination of intestinal microecological regulation and chemotherapy to provide new treatment strategies and basis for lung cancer patients. (biomedcentral.com)
  • Patients will be randomised in a 1:1 ratio into one of the two treatment arms. (biomedcentral.com)
  • This study provides a step toward precision therapeutics for PTSD by demonstrating that comorbid MDD and genetic markers may help guide treatment selection. (nature.com)
  • Anorexia nervosa and atypical anorexia nervosa are by far the most prevalent eating disorders among patients admitted to child and adolescent psychiatric (CAP) treatment or to paediatric units with a CAP liaison service, whereas patients with bulimia nervosa and avoidant/restrictive food intake disorder (ARFID) are seen comparatively less often. (lww.com)
  • Evidence on the efficacy of immunonutrition during immunotherapy in these patients is positive, but still limited some secondary endpoints, such as treatment toxicity and tolerance. (biomedcentral.com)
  • Study endpoints were: treatment response (primary endpoint: progression-free survival), treatment tolerance and toxicity, body weight, body composition, protein-calorie intake, quality of life, fatigue, muscle strength and immunological profile. (biomedcentral.com)
  • The present pilot study, which guarantees early high-quality nutritional care (assessment and treatment) to all patients in agreement with current guidelines and recommendations, could represent one of the first proofs of efficacy of early oral immunonutrition in patients with cancer undergoing immunotherapy. (biomedcentral.com)
  • 3 , 4 In some studies, exercise programmes were started or carried out at the same time as pharmacological treatment or psychotherapy. (bmj.com)
  • Unfortunately, key aspects of the addiction treatment Lute described were outdated and have been shown to backfire in studies. (time.com)
  • Not one study has ever found that disrespecting or humiliating people with addiction is effective treatment. (time.com)
  • Patients had 24 hour Holter monitoring and a 6 minute exercise test on the last day of each treatment period. (bestbets.org)
  • Barriers surrounding the healthcare system seem to hinder patients to seek help through conventional healthcare, even after entering opioid substitution treatment (OST), resulting in a high level of unmet healthcare needs. (hindawi.com)
  • Patients in opioid substitution treatment (OST) are suspected to suffer from poor health due to prior, or ongoing, substance use [ 1 ]. (hindawi.com)
  • Health-related quality of life (HRQoL) is an important outcome measure in patients with COPD, and increasingly used to quantify symptom burden and guide treatment. (bmj.com)
  • Treatment with a new class of drugs, called senolytics, in donors improved the physical fitness of the recipients, a new study has shown. (medicaldaily.com)
  • The study indicates the possibility of using heated yoga as a viable treatment option for depression, as 44% of the participants who took up the sessions indicated signs of remission. (medicaldaily.com)
  • Over 20% of patients taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, suffer from the rebound, compared to less than the 2% chance seen in other treatment groups, a Harvard Medical School study revealed. (medicaldaily.com)
  • Gut-directed hypnotherapy is an effective treatment alternative for patients with refractory IBS, but the effectiveness is lower when the therapy is given outside the highly specialized research centers. (researchgate.net)
  • For people who are severely obese, bariatric operations can provide a "treatment modality for obesity," the study authors noted. (disabled-world.com)
  • The first order of business seems to make sure we adequately study these new combinations and treatment strategies before mounting an antiretroviral Marshall Plan. (treatmentactiongroup.org)
  • Previous studies have shown mindfulness works better than no treatment or at least as well as education or more formal behavior therapy in reducing anxiety, depression and other mental woes. (saanichnews.com)
  • Ten patients on the drug dropped out because of troublesome side effects possibly related to treatment, which included insomnia, nausea and fatigue. (saanichnews.com)
  • But the study also raises important questions about whether trials on biologics-pharmaceutical or herbal-alone truly address the multiple layers of depression treatment. (naturalmedicinejournal.com)
  • It is likely that expanding treatment by working on patient lifestyle choices and using dietary and psychological therapy concomitantly with the intervention would lead to greater benefits. (naturalmedicinejournal.com)
  • These results are quite similar with other studies with more intensive treatment in this setting. (ecancer.org)
  • This study intends to determine which treatment has the most optimal outcome for the benefit of future patients with an indication for reverse shoulder arthroplasty. (lu.se)
  • Refusal of the patient from the proposed treatment method. (who.int)
  • In a one-year period (April 2014 to March 2015), all patients with drug dependence who had been referred for treatment and attended for a first assessment were included in this study (N=242). (who.int)
  • From the patients' perspective, motivational inconsistencies were considered as the main reason for not starting or leaving treatment. (who.int)
  • The INCAS clinic, with This study was carried out in a group decades, drug treatment services have more than a decade of experience in of treatment-seeking clients of the IN- expanded dramatically, both in service the field of delivering drug treatment CAS clinic. (who.int)
  • Telephone Study, a randomized trial designed to improve medication treatment, titration and quality of life among patients with symptomatic diabetic peripheral neuropathy. (cdc.gov)
  • This trial aims to assess whether real-time collection and clinical feedback of patient treatment experiences can reduce patient symptom burden. (cdc.gov)
  • This can lead to technically induced dropout because some participants lack the technological know-how or the willingness to install the plug-in. (websm.org)
  • participants were nonsmoking female patients aged 18-50 years and scheduled for laparoscopic appendectomy or cholecystectomy, ASA at I-III, with no serious physical or mental diseases. (biomedcentral.com)
  • Study participants had seven sessions with a nutritionist during the first year, and four per year for the remaining of the study. (lu.se)
  • 66 patients with the chronic fatigue syndrome who had neither a psychiatric disorder nor appreciable sleep disturbance. (bmj.com)
  • These findings support the use of appropriately prescribed graded aerobic exercise in the management of patients with the chronic fatigue syndrome. (bmj.com)
  • Patients with the chronic fatigue syndrome perceive greater fatigue than healthy controls taking the same exercise. (bmj.com)
  • 10 Fitness training improved both aerobic capacity and myalgia more than flexibility exercises in patients with the "fibrositis/fibromyalgia syndrome," 13 a condition which overlaps with the chronic fatigue syndrome. (bmj.com)
  • Patients met the Oxford criteria for the chronic fatigue syndrome. (bmj.com)
  • 18 patients with chronic stable AF (>6/12). (bestbets.org)
  • Studies have shown that bariatric operations can alleviate chronic health issues like diabetes and arthritis for extremely obese people. (disabled-world.com)
  • For example, I often recommend Rhodiola rosea to patients who have a long-term history of chronic stress and have been tested to show high cortisol levels in the early morning that increase the patient's awakening response. (naturalmedicinejournal.com)
  • Substance use disorder is a chronic re- Addiction Studies (INCAS) could be sessions. (who.int)
  • it applies principles of the chronic care model, including community-clinic linkages, to the management of patients newly diagnosed with diabetes and prediabetes through screening. (cdc.gov)
  • Trial registration The study protocol was registered at clinicaltrials.gov (NCT04849130). (springer.com)
  • This study is registered at ClinicalTrials.gov , #CE-1304-7250. (cdc.gov)
  • There was a significantly lower number of patients free of new adenomas in the placebo group compared to those taking active medication as tested by logistic regression and Kaplan-Meier analysis (log-rank test p value 0.035). (nih.gov)
  • Dropout was significantly higher on the Java applet questionnaire page than on the preceding and subsequent questionnaire pages. (websm.org)
  • In a prospective intervention study of colorectal adenomas, and intermediary stage in colorectal carcinogenesis, 116 polyp-bearing patients received a placebo-controlled daily mixture of beta-carotene 15 mg, vitamin C 150 mg, vitamin E 75 mg, selenium 101 microg, and calcium (1.6 g daily) as carbonate for a period of 3 years with annual colonoscopic follow-up to test if the mixture was able to reduce polyp growth or recurrence. (nih.gov)
  • 87-91% of the patients attended the annual endoscopic follow-up investigations, and 19% of the patients dropped out of the medical intervention. (nih.gov)
  • Patients with type 2 diabetes were recruited by postal invitation letter from their medical practice and randomised via automated system to intervention or usual care. (bmj.com)
  • Stakeholder meetings were held before and after intervention to develop study design and learn from its implementation. (bmj.com)
  • 32 students provided the complete intervention to 58 patients. (bmj.com)
  • The intervention was found to be feasible and acceptable to patients. (bmj.com)
  • The trial was unblinded with the service providers, patients and research all aware of group allocation and intervention content. (bmj.com)
  • In this particular study, like most double-blind studies, the only change in patient care was the pharmaceutical or herbal intervention. (naturalmedicinejournal.com)
  • Furthermore, it has the potential to be a more cost-effective intervention for patients who cannot easily access their local centre or hospital. (rrh.org.au)
  • We plan to Author Manuscript compare changes in self-reported quality of life between the intervention group and patients in the control group who receive three non-interactive automated educational phone calls. (cdc.gov)
  • In the 12-week placebo-controlled dose-response study, patients were randomized to placebo or to doses of 0.5, 1, 2, and 3 mg of guanfacine, in addition to 25 mg chlorthalidone, each given at bedtime. (nih.gov)
  • In a second 12-week placebo-controlled study 1, 2, or 3 mg of guanfacine hydrochloride administered with 25 mg chlorthalidone once daily, a significant decrease in blood pressure was maintained for a full 24 hours after dosing. (nih.gov)
  • This study was a phase-2 randomized, placebo-controlled trial. (naturalmedicinejournal.com)
  • This study is the first time Rhodiola rosea was compared to selective serotonin reuptake inhibitor like sertraline in a double-blind placebo-controlled randomized trial. (naturalmedicinejournal.com)
  • As clinical associate director of neurology at Allegheny Medical Center, Pittsburgh, he has overseen the care of several hundred patients with generalized MG, as well as participated in clinical trials. (medscape.com)
  • In phase III trials, they expand their research to include more patients in more places. (webmd.com)
  • Clinical trials often involve thousands of patients who volunteer to take the experimental drug. (webmd.com)
  • Twenty two trials compared antispasmodics with placebo in 1778 patients (0.68, 0.57 to 0.81). (bmj.com)
  • Four trials compared peppermint oil with placebo in 392 patients (0.43, 0.32 to 0.59). (bmj.com)
  • Controlled clinical trials in patients with mild to moderate hypertension who were receiving a thiazide-type diuretic have defined the dose-response relationship for blood pressure response and adverse reactions of guanfacine given at bedtime and have shown that the blood pressure response to guanfacine can persist for 24 hours after a single dose. (nih.gov)
  • We provided an end-to-end solution for recruiting and screening patients for clinical trials . (firstsource.com)
  • By making the clinical trial process more convenient for enrollment and participation, industry leaders can gain better research results, fewer failed trials, and more trust from physicians and patients. (within3.com)
  • Learn how to improve patient recruitment in clinical trials . (within3.com)
  • The Finnish Diabetes Prevention Study (DPS) was among the first diabetes prevention trials ever made (1). (lu.se)
  • History of abuse of alcohol or any chemical substances for 2 years up to the 10th day before the start of the study. (who.int)
  • In the MycarinG study, rozanolixizumab "showed both statistically significant and clinically meaningful improvements in multiple endpoints," said Vera Bril, MD, during a presentation of the results. (medscape.com)
  • Analysis by intention to treat gave similar results (17/33 v 9/33 patients better). (bmj.com)
  • The results from this study will help to gather valuable knowledge on the use of rehabilitation with a new VR tool in MS patients. (frontiersin.org)
  • Results The study enrolled 127 patients. (bmj.com)
  • Future studies are mandatory to support these preliminary results. (bmj.com)
  • Our results indicate that DuoVisc might be favoured in patients with cornea guttata or low endothelial cell count. (bmj.com)
  • Finally, the high percentage of drop outs in most studies renders interpretation of their results difficult. (bmj.com)
  • Results 792 patients were identified as eligible from five medical practices. (bmj.com)
  • The genetic study showed promising results in "silencing" the genes that translate into tau protein, the primary component behind dementia. (medicaldaily.com)
  • The preliminary results from the antiretroviral studies presented in Vancouver were stunning. (treatmentactiongroup.org)
  • The results of the study will clarify whether the reported surgery success for patella stabilization via dynamic MPFL reconstruction is due to muscle contraction or to the passive tenodesis effect combined with clinical outcome measures. (springer.com)
  • Study results, published Wednesday in the journal JAMA Psychiatry, are timely. (saanichnews.com)
  • But this is the first study to test it against a psychiatric drug, Hoge said, and the results could make insurers more likely to cover costs, which can run $300 to $500 for an 8-week session. (saanichnews.com)
  • The results were based on about 200 adults who completed the six-month study at medical centers in Washington, Boston and New York. (saanichnews.com)
  • Whether similar results would be found with online training or phone apps is unknown, said Krakower, who also had no role in the study. (saanichnews.com)
  • Results GORD was present in 203/308 (66%) patients. (bmj.com)
  • The ERMES study results did not demonstrate non-inferiority of maintenance with cetuximab alone. (ecancer.org)
  • The NGS analysis of tissue sample or liquid biopsy are ongoing in our study and we hope to present these results in our next meeting. (ecancer.org)
  • While there have been fewer studies of home-based cardiac rehabilitation, the available data suggest that it has comparable results to hospital-based programs. (rrh.org.au)
  • one considered a standard diabetes preventing diet and another with higher protein content and lower glycaemic index (GI) based on the successful results from the DiOGenes study (8). (lu.se)
  • The study started in 2013 and was finished in 2018, and the main results were recently published (7). (lu.se)
  • In this prospective single-center 6-months follow-up study, 32 and 16 MS patients will receive VRR or CR, respectively. (frontiersin.org)
  • REMED is a prospective, open-label, randomised controlled trial testing the superiority of dexamethasone 20 mg (dexamethasone 20 mg on days 1-5, followed by dexamethasone 10 mg on days 6-10) vs 6 mg administered once daily intravenously for 10 days in adult patients with moderate or severe ARDS due to confirmed COVID-19. (biomedcentral.com)
  • 16 In addition, by using the structured clinical interview for the DSM-III-R ( Diagnostic and Statistical Manual of Mental Disorders , third edition, revised) 17 we excluded patients who also had a current psychiatric disorder or symptomatic insomnia because of the separate effects of these conditions on fatigue. (bmj.com)
  • 3 patients (37.5%) given verapamil had to be withdrawn from the study due to symptomatic hypotension compared with none given diltiazem. (bestbets.org)
  • The study aimed to evaluate the short-term clinical effect, therapeutic response rate (TRR%), and therapy safety of a single intra-articular autologous MFAT injection for symptomatic knee OA. (mdpi.com)
  • Conclusions-- Innovative strategies are needed to guide improvements in healthcare delivery for patients with symptomatic diabetic peripheral neuropathy. (cdc.gov)
  • thus, most care for the patient with SMA is focused on symptomatic control and preventative rehabilitation. (medscape.com)
  • Our study aims to address this gap, mapping out the base on which future targeted healthcare can be built as OST clinics provide a unique opportunity to identify and to provide healthcare and support on a holistic level. (hindawi.com)
  • The study aims were to assess the responsiveness of the CCQ to PR, to compare the responsiveness of the CCQ to other HRQoL questionnaires and to provide estimates for the MCID. (bmj.com)
  • The toolkit aims to help patients who may have health equity challenges take charge of their health and consider PD. (homedialysis.org)
  • BestBets: Which is the best calcium channel blocker for controlling the ventricular rate in patients with atrial fibrillation? (bestbets.org)
  • Taller people may develop atrial fibrillation: Study. (asianage.com)
  • However, a reduction in connectivity within the DMN has also been reported amongst medicated patients and those with recurrent illness 9 . (nature.com)
  • Chemotherapy-naïve patients with pathologically-proven locally advanced, recurrent, or metastatic pancreatic adenocarcinoma were assessed for eligibility. (jcancer.org)
  • Patients with recurrent patella dislocation requiring isolated MPFL reconstruction will be recruited and randomized to the dynamic or static reconstruction technique. (springer.com)
  • This is necessary in recurrent patella dislocations and in particular cases of first patella dislocations such as patients with severe anatomical risk factors [ 15 ]. (springer.com)
  • 11 12 As a result general practitioners are increasingly responsible for the initial management of patients with irritable bowel syndrome and are expected to refer only a minority to secondary care. (bmj.com)
  • The fecal calcium concentration was 2.3-2.7 times higher in patients taking active medication compared to the placebo group. (nih.gov)
  • However, most patients seek healthcare from the private sector and some resort to alternative forms of medicine, often preferring self-medication and consulting quacks over visiting the PMDT center ( 6 , 7 ). (cdc.gov)
  • Second, connectivity changes in these regions have also been observed in remitted patients off medication and in populations with correlates of depression such as trauma, childhood maltreatment, subclinical depression and familial risk in children. (nature.com)
  • Objective To pilot and feasibility-test supervised final year undergraduate pharmacy student-led medication reviews for patients with diabetes to enable definitive trial design. (bmj.com)
  • He prescribes them with medication for patients with more severe anxiety. (saanichnews.com)
  • 1 , 2 However, care needs to be taken when applying these findings to patients with affective disorders. (bmj.com)
  • Findings from their single-site study are published in the November issue of the Journal of the American College of Surgeons . (disabled-world.com)
  • These findings provide evidence of a high prevalence of diabetes in psychiatric patients and that having diabetes has an adverse effect on outcome of psychiatric illness. (who.int)
  • The findings of this study could give service providers a better grasp of drop-out rates and the associated reasons. (who.int)
  • Enhanced recovery protocols (ERPs), such as prehabilitation, have been associated with a reduction in complications after CS in vulnerable patients. (bmj.com)
  • This study was conducted to discuss and analyze the strategy of diagnosis and management of complications following the use of mega-implants in treating primary and periprosthetic fractures of the lower extremities. (bvsalud.org)
  • The overall complication rate was 23.33% (21 complications in 21 patients). (bvsalud.org)
  • Diabetes-related clinical data, quality of life, patient reported beliefs, adherence and satisfaction with medicines information were collected with validated tools at baseline and 6 months postintervention. (bmj.com)
  • ABSTRACT We evaluated the prevalence of diabetes comorbidity in Greek psychiatric patients, differences between type 1 and type 2 diabetics and the outcome of psychiatric disorder. (who.int)
  • Existence of diabetes mellitus (regardless of type), duration of untreated mental illness and lack of patient therapeutic education were negative predictors of (unfavourable) outcome. (who.int)
  • The incidence of diabetes mellitus in psychiatric patients has been found to be 2 to 8 times higher than in the general population [1-3]. (who.int)
  • A 10% frequency of diabetes mellitus in patients with bipolar disorder (manic and mixed subtypes) has been reported [2]. (who.int)
  • A study in the United States based on medical records found a prevalence of 26% for diabetes inpatients with bipolar I disorder [4]. (who.int)
  • A Canadian study found a prevalence of 11.7% of diabetes mellitus in a community-based sample of individuals diagnosed with bipolar disorder [5]. (who.int)
  • Other studies suggest that diabetes doubles the risk of depression [7]. (who.int)
  • Screening high-risk patients to detect diabetes and prediabetes was cost-effective (7-9), and prevention of type 2 diabetes in people with prediabetes through adoption of appropriate lifestyle changes and pharmacologic interventions has been successful in experimental settings (10). (cdc.gov)
  • Six clinics in a primary care network in New York City, 3 of which are federally qualified health centers, have established an evidence-based diabetes management system grounded in CCM principles in the context of developing a patient-centered medical home in each clinic (14). (cdc.gov)
  • Our study will examine a standard and an enhanced diabetes management system. (cdc.gov)
  • The enhanced diabetes management system is designed to facilitate the management of patients identified through the screening program as having diabetes or prediabetes. (cdc.gov)
  • During the Prevention of type 2 diabetes session at the Nordic Nutrition Conference 2020 (14-16 December), it was made clear that prevention of type 2 diabetes is highly achievable, as has been proven in some important studies over the past decades. (lu.se)
  • Da Qing Diabetes Study (n=577 recruited 1986) could see decreased incidence in type 2 diabetes in the diet group, physical activity group and the diet+physical activity group (36-53%) compared to control after 6 years (3). (lu.se)
  • From these studies, it became evident that type 2 diabetes can be prevented with lifestyle modifications. (lu.se)
  • The DIRECT (Diabetes Remission Clinical Trail) study had their focus on reversing newly diagnosed diabetic patients rather than on diabetes prevention. (lu.se)
  • Their objective was based on that other studies have indicated that a 15 kg weight loss could normalise life expectancy in individuals with type 2 diabetes. (lu.se)
  • In the DIRECT study, 298 patients who have been diagnosed with type 2 diabetes maximum 6 years ago were taken out of their medications and instead started a 3 months low calorie diet with total diet replacement. (lu.se)
  • This study indicates how plausible type 2 diabetes remission actually is within the primary health care, as long as we have enough resources to focus on this issue. (lu.se)
  • Among these, 3,1% developed type 2 diabetes during the three year long study. (lu.se)
  • However, the Diabetes Telephone Study research team welcomes collaborations and anyone interested in possible scientific collaboration should contact the corresponding author, Dr. Alyce Adams. (cdc.gov)
  • Conclusions Student and patient recruitment are possible. (bmj.com)
  • Recently, several major SMOs have diversified their operations to include patient recruitment, pharmacogenomic and traditional CRO services. (centerwatch.com)
  • Volunteer-patients are critical to their success, but recruitment is complex and challenging. (firstsource.com)
  • Presumptive MDR TB patients, when referred to PMDT centers, are subjected to drug sensitivity testing, preferably by use of a rapid molecular test (cartridge-based nucleic acid amplification assay), line probe assay, or culture, per PMDT guidelines ( 10 ). (cdc.gov)
  • However, randomized, controlled studies are rare and few have been performed outside highly specialized research centers. (researchgate.net)
  • Because more than 80% of PDAC is locally advanced unresectable or metastatic at the time of diagnosis [ 2 ], the prognosis of PDAC patients is dismal with a 5-year relative survival rate of 11.4% [ 3 ]. (jcancer.org)
  • Dr Armando Orlandi speaks to ecancer about ERMES, a phase III study which looked at FOLFIRI/cetuximab versus FOLFIRI/cetuximab followed by cetuximab alone in first-line therapy of RAS and BRAF wild-type metastatic colorectal cancer patients. (ecancer.org)
  • ERMES is a phase III trial investigating the efficacy of the maintenance therapy with cetuximab alone after induction with FOLFIRI plus cetuximab in the RAS and BRAF wildtype metastatic colorectal cancer patients. (ecancer.org)
  • Patients will consume their assigned supplement two times per day for approximately 2 weeks pre-procedure, during in-hospital postoperative recovery and for 8 weeks following discharge. (bmj.com)
  • The aim of this study was to investigate whether the application of OFA by using esketamine in intraoperative analgesia could minimize the side effects of postoperative nausea and vomiting (PONV), as well as other short-term side effects related to anaesthesia. (biomedcentral.com)
  • The proportion of eligible patients who successfully complete a cardiac rehabilitation program remains low. (rrh.org.au)
  • However, despite the evidence and inclusion of cardiac rehabilitation in national rehabilitation guidelines 4-7 , there is a lack of standardisation with respect to what a cardiac rehabilitation program should include, and participation of eligible patients in cardiac rehabilitation remains poor 8 . (rrh.org.au)
  • This study will seek to investigate the efficacy of "Microbiota modulation of the Gut-Lung Axis" combined with chemotherapy in patients with advanced NSCLC. (biomedcentral.com)
  • Based on the theoretical basis of "intestinal and lung axis microecological adjustment", combined with traditional platinum-containing two-drug chemotherapy, the efficacy of the new therapy on patients with advanced NSCLC was observed. (biomedcentral.com)
  • We aim to compare two different doses of dexamethasone in patients with moderate to severe ARDS undergoing mechanical ventilation regarding efficacy and safety. (biomedcentral.com)
  • We designed the present study to evaluate the efficacy of early systematic provision of ONS enriched with immunonutrients compared to nutritional counseling alone, in patients with NSCLC undergoing immunotherapy. (biomedcentral.com)
  • Patient-reported knee function and anterior knee pain as assessed with the Kujala score will serve as primary outcome. (springer.com)
  • Patients were assessed at baseline using the HAM-D as the primary outcome assessment with the Beck Depression Inventory (BDI) and Clinical Global Impression Change (CGI/C) scores for secondary outcome measurements. (naturalmedicinejournal.com)
  • We hypothesize that the lateralization improves the patient outcome by decreasing the risk of inferior scapular notching without increasing the risk of migration and loosening of glenoid component. (lu.se)
  • Discussion: No previous studies have compared the conventional reverse shoulder arthroplasty with the lateralized reverse shoulder arthroplasty in a randomized controlled trial regarding migration and functional outcome. (lu.se)
  • The Malmö Addiction Centre, geographically located within the Malmö University Hospital, includes an emergency addiction unit, an in-patient detox ward for opioid dependence and a psychiatric emergency unit. (hindawi.com)
  • Short patient self-report (written completion without assistance from another person) diagnostic questionnaires are used in family practice as standardised instruments to aid the symptom-based diagnosis of several highly prevalent disorders. (bmj.com)
  • Today, most studies regarding the prevalence of homosexuality involve adult subjects (5-10%), but these figures also appear to be consistent with the available data concerning adolescents. (medscape.com)
  • Due to their high reactivity to environmental stimuli, patients with BPD often experience dramatic and short-lived shifts in their mood, alternating between experiences of euphoria, depression, anxiety, and nervousness. (wikipedia.org)
  • Objective -To evaluate the short term effects of a training programme on patients with moderate to severe major depression. (bmj.com)
  • A total of 57 subjects with mild to moderate major depression (MDD) were recruited for this study. (naturalmedicinejournal.com)
  • If patients were assessed to be at less than 50% reduction of the Hamilton Depression Rating (HAM-D) scale, the dosage was moved up to 2 capsules daily for weeks 3 and 4. (naturalmedicinejournal.com)
  • This study pitting Rhodiola rosea against sertraline is consistent with a greater body of research that shows minimal but measurable effects for monotherapeutic approaches to mild and moderate depression. (naturalmedicinejournal.com)
  • Studies reveal that strong link found between level of depression and heart disease, stroke. (asianage.com)
  • Researchers find one in five cardiac rehab patients suffers from depression. (asianage.com)
  • A study by Madsen et al indicated that cycle training improves maximal oxygen uptake (VO 2max ) in patients with Kugelberg Welander SMA, but at the cost of significant fatigue. (medscape.com)
  • However, fatigue led one patient to drop out of the study and two others to require training modifications, with three patients experiencing an increased need for sleep. (medscape.com)
  • Affected school-age patients may benefit from an occupational therapy consultation that addresses keyboarding and other ways to avoid fatigue from upper extremity activities in the classroom. (medscape.com)
  • The dose-response relationship for blood pressure and adverse effects of guanfacine given once a day as monotherapy has been evaluated in patients with mild to moderate hypertension. (nih.gov)
  • While most of the effectiveness of guanfacine in combination (and as monotherapy in white patients) was present at 1 mg, adverse reactions at this dose were not clearly distinguishable from those associated with placebo. (nih.gov)
  • The decline in HAM-D was greater for sertraline vs Rhodiola rosea (‒8.2 vs ‒5.1) or placebo (‒4.6), with more patients suffering adverse reactions with sertraline (63.2%) over Rhodiola rosea (30.0%) or placebo (16.7%) ( P =0.012). (naturalmedicinejournal.com)
  • Serious adverse events occurring in the patient during the study. (who.int)
  • Alain Labrique, PhD, professor and associate chair of research at Johns Hopkins Bloomberg School of Public Health (JHSPH) and chair of the World Health Organization (WHO) digital health guidelines development group discusses with us the ongoing research study, National Pandemic Pulse, he and his colleagues are performing in the US. (pharmaphorum.com)
  • Objectives: This study explored and described university nursing students' challenges in relation to e-learning during the early stages of the COVID-19 pandemic in a resource-constrained setting. (bvsalud.org)
  • Nutritional support, including nutritional counseling and oral nutritional supplements (ONS), has been recommended as a first-line strategy in patients with non-small cell lung cancer (NSCLC). (biomedcentral.com)
  • We hypothesize that early systematic provision of ONS with a high-protein-high calorie mixture containing immunonutrients (Impact®) in addition to nutritional counseling, compared to nutritional counseling alone, is beneficial to patients with NSCLC receiving immunotherapy with or without chemotherapy. (biomedcentral.com)
  • Since diagnosis, patients with non-small cell lung cancer (NSCLC) frequently present a variable impairment of nutritional status. (biomedcentral.com)
  • Given that information on patient satisfaction with VRR is scarce, the primary objective of this study is to assess long-term patient satisfaction with a novel VRR program. (frontiersin.org)
  • The objective of this study was to study the effect of gut-directed hypnotherapy in IBS in different clinical settings outside the traditional research units. (researchgate.net)
  • During the Q&A session, George Small, MD, asked if the study had shown a reduction in steroid use among patients with MG. (medscape.com)
  • For patients who still had less than a 50% HAM-D scale reduction were moved up to 3 capsules daily during weeks 5 and 6. (naturalmedicinejournal.com)
  • After 6 weeks, if reduction still did not improve to a 50% HAM-D reduction vs baseline, dosage was increased to 4 capsules for the remainder of the study. (naturalmedicinejournal.com)
  • One author reports 50% of patients with SMA type III have hip subluxation or dislocation, with rare improvement in function from surgical reduction. (medscape.com)
  • Several studies have described an improvement in mood of healthy persons after participation in a physical activity programme. (bmj.com)
  • What are the non-clinical issues that cause patients to discontinue trial participation? (within3.com)
  • Patient participation in another clinical trial. (who.int)
  • Future studies should test these hypotheses in high-risk patient populations, such as those affected by endothelial corneal dysfunction or glaucoma/hypertension. (bmj.com)
  • [ 1 , 2 ] In 1993, Diamond and colleagues performed a review of studies conducted with various populations and concluded that the prevalence of predominant homosexual attraction was lower than Kinsey had predicted. (medscape.com)
  • At the 2023 annual meeting of the American Association for Neuromuscular and Electrodiagnostic Medicine (AANEM), researchers presented data from an open-label extension study following the phase 3 MycarinG trial of rozanolixizumab and the ADAPT-SC+ study of efgartigimod. (medscape.com)
  • Study volunteers have clearly defined rights, such as the right to drop out of the trial at any time. (webmd.com)
  • The pilot and feasibility study enabled the design of a future full randomised controlled trial. (bmj.com)
  • Clinical trial timelines are designed to ensure that new treatments are safe and effective for patients. (within3.com)
  • Study sponsors can suffer severe setbacks if enrollees don't complete a trial. (within3.com)
  • It's important to remember that patients are regular people dealing with work, family, and possibly health issues, which may interfere with prescribed trial activities. (within3.com)
  • Trial registration: The study has been notified to Pactius and has approval number P-2021-231. (lu.se)
  • At the University Health Network's program, patients then go through several assessments, including an orientation followed by a nursing consultation, a nutrition class and dietitian assessment, and an evaluation by a social worker. (disabled-world.com)
  • Less obese patients: Patients with a BMI of 35 to 40 were also more likely to drop out, especially after the orientation or the nutritional assessment. (disabled-world.com)
  • Draft Summary of Product Characteristics (SmPC), Patient Information Leaflet (PIL) and labels should be included as prepared using the format provided in the medicines section of the WHO prequalification website (under WHO Public Assessment Reports). (who.int)
  • Conclusions -Aerobic exercise can produce substantial improvement in mood in patients with major depressive disorders in a short time. (bmj.com)
  • Many physicians use steroids for very quick responses in their patients. (medscape.com)
  • Toxicities were evaluated in 36 patients, and the responses were evaluated in 32 patients. (jcancer.org)
  • To determine those out-of-pocket expenses, we interviewed 40 presumptive patients and found that they spent more than their median annual income before registering for the government program. (cdc.gov)
  • In recent years, a very close relationship between the gut-lung axis microecology and malignant tumors have been found in some studies. (biomedcentral.com)
  • Moderate exercise for 20 minutes after a sleepless night can improve brain power, a new study has found. (medicaldaily.com)
  • The study suggests the possibility of using trans-vaccenic acid found in red meat and dairy products as a nutritional supplement to complement treatments for cancer. (medicaldaily.com)
  • The investigators found that the patients' VO 2max improved during their training by 27%, with no occurrence of muscle damage. (medscape.com)
  • As defined by the National Committee for Quality Assurance, a patient-centered medical home is a health care setting that facilitates partnerships between patients and their physicians through the use of registries, information technology, and health information exchange. (cdc.gov)
  • One of the key features for rehabilitation adherence is patient satisfaction with the VR rehabilitation (VRR) program, and information on user satisfaction and not only effectiveness is required to systematically include VRR in routine clinical practice. (frontiersin.org)
  • Patients who completed the flexibility programme were invited to cross over to the exercise programme afterwards. (bmj.com)
  • To assess OST patients' self-rated physical health and healthcare seeking behaviour. (hindawi.com)
  • Two-hundred and eighteen patients from four different OST sites answered a questionnaire regarding physical health and healthcare seeking. (hindawi.com)
  • Patients' frequent visits to the OST clinics offer a unique opportunity to build a base for easily accessible on-site primary healthcare. (hindawi.com)
  • conclude that only a few studies have examined the broader public health challenges and unmet healthcare needs within the OST population [ 16 , 17 ]. (hindawi.com)
  • The aim of this study is to assess OST patients' self-rated physical health and healthcare seeking behaviour. (hindawi.com)
  • If you are a patient, please refer your questions to your healthcare provider. (cdc.gov)
  • Following the approval of gemcitabine by the US Food and Drug Administration in 1997 [ 4 ], gemcitabine-based chemotherapy was considered the standard of care for patients with advanced PDAC for a decade. (jcancer.org)
  • Allergy to components of the study drug. (who.int)
  • After completing MycarinG, patients were eligible to enroll in one of two open-label studies, one of each dose. (medscape.com)
  • 44 healthy controls (age: 33.8 (10.5), 73% female) and 84 patients (age: 34.23 (10.8), 80% female) were included in the analysis. (nature.com)
  • In total, 72 patients were included in the final analysis. (medsci.org)
  • Certificates of analysis should be included for the biobatch of the proposed product and the relevant batch of the comparator product, analysed at a time near the time of the BE study. (who.int)
  • There will be included a total of 122 patients of which 56 will participate in the radiostereometric analysis. (lu.se)
  • Study suggests high BMI may improve cancer survival. (asianage.com)
  • Objective The aim of this study was to determine the accuracy of the diagnosis of gastro-oesophageal reflux disease (GORD) by the Reflux Disease Questionnaire (RDQ), family practitioners, gastroenterologists and a test of esomeprazole therapy. (bmj.com)
  • This population- based study investigated food groups intaken by means of a quantitative food frequency questionnaire (QFFQ) validated for use in Brazil. (bvsalud.org)
  • No difference was detected in the growth of adenomas between the active and the placebo group from year to year and for the total study period. (nih.gov)
  • Patients undergoing TKR were randomly allocated to not receive RIPC (control group) and to receive RIPC (RIPC group). (medsci.org)
  • There were no dropouts for that reason in the mindfulness group, although 13 patients reported increased anxiety. (saanichnews.com)
  • Twenty patients were randomized to the Rhodiola rosea group, 19 to the sertraline group, and 18 to the placebo group. (naturalmedicinejournal.com)
  • We will stagger implementation of the enhanced system across the 6 clinics allowing comparison, through a quasi-experimental design (pre-post difference with a control group), of patients treated in the enhanced system with similar patients treated in the standard system. (cdc.gov)
  • 133 cases of OSCC, selected from reference hospitals for cancer in Paraíba and 532 being part of a control group, paired by age, gender, place and smoking habit took part in the study. (bvsalud.org)
  • Altered gastrointestinal motility may contribute to the change in bowel habit reported by some patients, 5 and a combination of smooth muscle spasm, visceral hypersensitivity, and abnormalities of central pain processing may explain the abdominal pain that is an essential part of the symptom complex. (bmj.com)
  • Only 49% of the patients with GORD selected either heartburn or regurgitation as the most troublesome symptom. (bmj.com)
  • This has been supported by animal experimental studies, case control and cohort studies. (nih.gov)
  • Hence, we estimated the direct and indirect out-of-pocket expenses incurred for diagnosis and pretreatment evaluation by presumptive MDR TB patients in Mangalore, India. (cdc.gov)