• genes
  • A number of Listeria monocytogenes strains of different origins are evaluated for invitro invasion capacity for various human cell types and for expression levels of specific virulence genes. (readabstracts.com)
  • The findings reveal that the observation led to study the mRNA expression levels of inlA, inlB, and ami, important virulence genes mediating adhesion and eukaryotic cells, by real-time reverse transcription-PCR for 27 clinical and 37 nonclinical Listeria monocytogenes strains. (readabstracts.com)
  • We also showed that the infecting Treponema pallidum strain type and polymorphisms in host toll like receptor genes increase neurosyphilis susceptibility. (washington.edu)
  • The molecular mechanisms underlying DNA repair were also examined by transcriptomics leading to the description of a repertoire of genes responding to acute gamma irradiation, including genes involved in DNA replication, repair and recombination, cell wall metabolism, cellular transport and many with uncharacterized functions. (wikipedia.org)
  • biological
  • Here, we review recent progress in the application of modern molecular techniques to understanding the biological basis of this multistage disease and to the development of new tools for diagnosis, for predicting efficacy of treatment with alternative antibiotics, and for studying the transmission of infection through population networks. (pubmedcentralcanada.ca)
  • Φ29 phage, a phage of Bacillus, is a paradigm for the study of several molecular mechanisms of general biological processes, including DNA replication and regulation of transcription. (wikipedia.org)
  • genetic
  • The rDNA spacer regions provide easily accessible, polymorphic genetic loci for both species and strain identification of dermatophyte fungi. (aber.ac.uk)
  • The cohort was identified at birth from the general population based on genetic testing for the HLA genotype conferring the highest genetic risk of type 1 diabetes, DRB1 * 0401-DQA1 * 03-DQB1 * 0302/DRB1 * 03-DQA1 * 05-DQB1 * 02 . (diabetesjournals.org)
  • We show that in laboratory-derived mutants of Mycobacterium tuberculosis, rifampin resistance is universally associated with a competitive fitness cost and that this cost is determined by the specific resistance mutation and strain genetic background. (stanford.edu)
  • antibiotics
  • Specialized culture media have been developed to better differentiate between MSSA and MRSA and in some cases, it will identify specific strains that are resistant to different antibiotics. (wikipedia.org)
  • The emergence of a new and highly toxic strain of C. difficile that is resistant to fluoroquinolone antibiotics such as ciprofloxacin and levofloxacin, said to be causing geographically dispersed outbreaks in North America, was reported in 2005. (wikipedia.org)
  • sporadic
  • WE are only kidding ourselves with the current diagnostic criteria for human and animal TSE, especially differentiating between the nvCJD vs the sporadic CJD strains and then the GSS strains and also the FFI fatal familial insomnia strains or the ones that mimics one or the other of those TSE? (vegsource.com)
  • detection
  • Amplification of these repeats using specific PCR, or their detection by Southern hybridisation with a generic ribosomal DNA probe, provides a sensitive and discriminatory technique for strain identification in T. rubrum and other dermatophyte fungi. (aber.ac.uk)
  • sequences
  • These researchers recognized the diversity of the DR-intervening sequences among different strains of M. tuberculosis and used this property to design a typing method that was named spoligotyping, which is still in use today. (wikipedia.org)
  • pathogenesis
  • However, an interpretation of virus occurrence at or shortly after diagnosis is difficult with respect to type 1 diabetes pathogenesis, because the autoimmune process starts months to years before its clinical manifestation. (diabetesjournals.org)
  • The evidence for involvement of enterovirus in type 1 diabetes pathogenesis comes predominantly from the Finnish population ( 4 - 6 ), whereas a study from Colorado ( 7 ) and one from Germany ( 8 ) did not find any significant association. (diabetesjournals.org)
  • biology
  • Bacteriophages, or "phage", have been fundamental in the development of the science of molecular biology and became "model organisms" for probing the basic chemistry of life. (wikipedia.org)
  • After attending school in Colmar, Horvath studied cellular and molecular biology at the Université Louis Pasteur, Strasbourg, where he obtained a Master's in 1996 and a Ph.D. in 2000. (wikipedia.org)
  • clinical
  • Accumulation and Transmission are key to the threshold from subclinical to clinical disease, and of that, I even believe that physical and or blunt trauma may play a role of onset of clinical symptoms in some cases, but key to all this, is to stop the amplification and transmission of this agent, the spreading of, no matter what strain. (vegsource.com)
  • Molecular techniques have had a direct influence on the clinical practice of medical microbiology. (wikipedia.org)
  • different
  • While there are different types of strain, the strain energy associated with all of them is due to the weakening of bonds within the molecule. (wikipedia.org)
  • When the heat of formation for a compound is different from either a prediction or a reference compound, this difference can often be attributed to strain. (wikipedia.org)
  • identification
  • Molecular identification and strain typing of dermatophyte fungi. (aber.ac.uk)
  • The data also suggest that recombinant isolates in Brazil often have unusual serological reactivity which may hamper their correct identification by conventional typing based on enzyme-linked immunosorbent assay. (apsnet.org)
  • toxin
  • C. perfringens is subdivided to 5 groups (types A to E), based on its four major toxin (alpha, beta, epsilon and iota). (ibbj.org)
  • C. perfringens type B beta toxin causes inflammation and bloody necrotic enteritis. (ibbj.org)
  • Toxin B (cytotoxin) induces actin depolymerization by a mechanism correlated with a decrease in the ADP-ribosylation of the low molecular mass GTP-binding Rho proteins. (wikipedia.org)
  • infections
  • 5.Arciola CR, Baldassarri L, Montanaro L. Presence of icaA and icaDGenes and slime production in a collection of Staphylococcal strains from catheter-associated infections. (ac.ir)
  • techniques
  • Molecular microbiology techniques are currently being used in the development of new genetically engineered vaccines, in bioremediation, biotechnology, food microbiology, probiotic research, antibacterial development and environmental microbiology. (wikipedia.org)
  • human
  • Human enteroviruses have been considered as possible environmental triggers or accelerators of islet autoimmunity leading to type 1 diabetes ( 1 , 2 ). (diabetesjournals.org)
  • In view of these conflicting results, we aimed to test whether the presence of human enterovirus in monthly fecal samples predicted development of repeated positivity for two or more diabetes-associated islet autoantibodies in children with the HLA genotype conferring the highest risk for type 1 diabetes. (diabetesjournals.org)
  • produce
  • Multiple sets of tandem repeats that vary in copy number both within and between strains produce length heterogeneity in the nontranscribed spacer(NTS) region. (aber.ac.uk)
  • Pathogenic C. difficile strains produce multiple toxins. (wikipedia.org)
  • produces
  • S. proteamaculans HY-3 isolated from the digestive tract of a spider produces an extracellular protease named arazyme, with an estimated molecular mass of 51.5 kDa. (wikipedia.org)
  • horizontal
  • These findings support the hypothesis that the strains are spread within the hospital via cross or horizontal transmission through hospital employees or medical instruments. (minervamedica.it)
  • identical
  • Of the 10 isolates from the recombinant PVY N:O/N-Wi strain group, 1 isolate, MAF-VOY, was found to have an unusual serological profile identical to the nonrecombinant PVY O -O5 strain group. (apsnet.org)
  • There are situations where seemingly identical conformations are not equal in strain energy. (wikipedia.org)
  • specific
  • Here, a panel of 36 PVY isolates, randomly collected in Brazil from potato between 1985 and 2009, was subjected to a systematic molecular and serological typing using reverse-transcription polymerase chain reaction and a series of PVY O - and PVY N -specific monoclonal antibodies. (apsnet.org)
  • found
  • It was found that MDR strains were frequently isolated from patients who underwent surgical interventions or patients in the intensive care units. (minervamedica.it)
  • They are found in various types of soils and waters and are occasionally found in foodstocks. (wikipedia.org)
  • Comparison
  • In chemistry, a molecule experiences strain when its chemical structure undergoes some stress which raises its internal energy in comparison to a strain-free reference compound. (wikipedia.org)
  • Study
  • The children prospectively observed in this study participate in the Norwegian cohort entitled "Environmental Triggers of Type 1 Diabetes: The MIDIA Study. (diabetesjournals.org)
  • Molecular microbiology is the branch of microbiology devoted to the study of the molecular basis of the physiological processes that occur in microorganisms. (wikipedia.org)
  • compare
  • First, one could compare to a similar compound that lacks strain, such as in the previous methylcyclohexane example. (wikipedia.org)
  • frequently
  • They have been observed more frequently in patients in whom type 1 diabetes was recently diagnosed compared with control subjects, and there is also evidence of the virus in the pancreata of subjects who died shortly after disease onset ( 3 ). (diabetesjournals.org)
  • suggest
  • Taken together, the data obtained suggest that the two recombinant strains, PVY NTN and PVY N:O/N-Wi , now are apparently dominant in the Brazilian potato crop. (apsnet.org)