• Surface functional electrical stimulation (FES) of abdominal wall muscles can be used to increase tidal volume (VT) and improve cough peak flow (CPF) in tet raplegic subjects who are able to breathe spontaneously. (iospress.com)
  • Although aMS was not demonstrably supramaximal in normal subjects, the mean value of twitch transdiaphragmatic pressure (Tw Pdi) obtained at 100% of stimulator output, 23.7 cmH2O, did not differ significantly from that obtained with bilateral supramaximal electrical stimulation (ES), 24.9 cmH2O, or bilateral anterior magnetic phrenic nerve stimulation (BAMPS), 27.3 cmH2O. (nih.gov)
  • Therefore, this new research, which administers epidural electrical stimulation (EES) offers the possibility of an alternative, non-pharmacological treatment. (reachmd.com)
  • The Hoffmann reflex, an involuntary reaction to electrical stimulation of muscle afferent sensory fibreswas studied, as was the long latency reflex (LLR) using the Dueschl method in which electrical stimulation is superimposed on a slight voluntary contraction, Different fatiguing protocols were performed, and respiratory rate continuously recorded. (daneurope.org)
  • Research conducted in the last two decades suggests that neuromuscular electrical stimulation of the lower limb muscles (NMES) may be a „bridge" to conventional exercise or an alternative for patients with advanced. (medandlife.org)
  • SD 30), in eighteen subjects to evaluate whether respiratory arrest or hypoxic and hypercapnic chemoreceptor stimulation is the primary elicitor of splenic contraction and cardiovascular responses during apnea. (lu.se)
  • We conclude that respiratory arrest per se is an important stimulus for splenic contraction and Hb increase during apnea, as well as an important initiating factor for the apnea-associated cardiovascular responses and their oxygen-conserving effects. (lu.se)
  • Since the 1990s, it has become one of the most often used sedatives in paediatric EDs because it allows spontaneous respiration due to the maintenance of laryngeal and pharyngeal reflexes and is also associated with respiratory and cardiovascular stimulation [2]. (smw.ch)
  • Acute effects in animals included respiratory stimulation and violent tonic convulsions, causing respiratory depression and asphyxiation. (cdc.gov)
  • Serious' effects are those that evoke failure in a biological system and can lead to morbidity or mortality (e.g., acute respiratory distress or death). (cdc.gov)
  • This was followed 12 hours later by an acute decompensation resulting from an apparent sympathetically driven episode of autonomic instability and acute pulmonary oedema requiring immediate respiratory and haemodynamic support. (scielo.org.za)
  • CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
  • First, accumulation of ACh at postganglionic parasympathetic muscarinic acetylcholine receptors leads to parasympathetic activity of smooth muscle in the lungs, GI tract, heart, eyes, bladder, and secretory glands and increased activity in postganglionic sympathetic receptors for sweat glands. (medscape.com)
  • In Austria, for example, you can experience this at the Krimml Waterfalls, where the air enriched with negative ions has a particularly beneficial effect on the respiratory tract, balances the immune system and reduces stress. (eurohike.at)
  • A hike along the lakes, streams or through a gorge also have a positive effect on the respiratory tract and alleviate the stresses of daily life - a true anti-aging cure for the body. (eurohike.at)
  • Traveling CPAP devices, along with automated favorable respiratory tract stress equipments, are frequently used by people that have actually been suggested a CPAP maker. (douglascosta.shop)
  • It is indicated for the treatment of infections caused by susceptible organisms involving the respiratory tract. (medscape.com)
  • It is indicated for the prophylaxis or treatment of mild to moderately severe upper respiratory tract infections caused by organisms susceptible to low concentrations of penicillin G. (medscape.com)
  • Azide stimulated cardiac muscle and dilated coronary vessels directly, and stimulated the central nervous system, causing increased respiratory and cardiac rate and force. (cdc.gov)
  • It is a bronchial smooth muscle relaxant, a CNS stimulant, a cardiac muscle stimulant, and a diuretic. (drugs.com)
  • Potential serious side effects of ketamine are, amongst others, apnoea and laryngospasms, as well as cardiac and respiratory arrest. (smw.ch)
  • If the Apgar score is below 7 at the five-minute mark, some providers will check it a few minutes later to assess the effect of any action taken to correct any respiratory or cardiac concerns. (medlineplus.gov)
  • Eighteen patients (in 7 high facility hospitals) with severe respiratory failure received a low- and high-rate repetitive nerve stimulation test, and negative inspiratory pressure was measured. (nih.gov)
  • Repetitive nerve stimulation test showed no response in the most severe stage. (nih.gov)
  • On hospitalization day 4, a repeat EMG study showed no response to repetitive nerve stimulation. (cdc.gov)
  • Third, as OPs cross the blood-brain barrier, they may cause seizures, respiratory depression, and CNS depression for reasons not completely understood. (medscape.com)
  • Paralysis of the respiratory muscles in people with tetraplegia affects their ability to breathe and contributes to respiratory complications. (iospress.com)
  • She had unresponsive pupils dilated to 5 mm, minimal extraoccular muscle motion, facial paralysis, normal palatal and gag reflexes, near-paralysis of proximal upper and lower extremities but near normal muscle strength in the hands and feet, and symmetric deep tendon reflexes. (cdc.gov)
  • Guillain-Barré syndrome (GBS) is a rare disorder in which a person's own immune system damages the nerve cells, causing muscle weakness and sometimes paralysis. (cdc.gov)
  • The neural damage is present in more advanced phases, and it can cause paresthesias and muscle paralysis(1). (bvsalud.org)
  • Message Body (Your Name) thought you would like to see the European Respiratory Society web site. (ersjournals.com)
  • His interest in respiratory physiology and sleep-disordered breathing brought him to London on a long-term research fellowship of the European Respiratory Society (ERS). (guysandstthomasevents.co.uk)
  • Skeletal muscle is vital for life, underpinning locomotion, respiration, and metabolism, yet we still poorly understand its response to exercise and disease. (leeds.ac.uk)
  • The somatic system includes both the central and the peripheral neurons that convey impulses from the sense organs, organize them in the brain, and deliver motor impulses to the skeletal muscles. (druglibrary.net)
  • The pathophysiology of dyspnoea is complex, and involves the activation of several pathways that lead to increased work of breathing, stimulation of the receptors of the upper or lower airway, lung parenchyma, or chest wall, and excessive stimulation of the respiratory centre by central and peripheral chemoreceptors. (samj.org.za)
  • AIM:We wished to study the link between peripheral muscle fatigue, the concomitant alteration of long latency (transcortical) reflexes and respiratory control. (daneurope.org)
  • Tw was performed to diaphragm and abdominal muscles (T10) pre and post cycle. (ersjournals.com)
  • Anterior magnetic stimulation (aMS) of the phrenic nerves is a new method for the assessment of diaphragm contractility that might have particular applications for the clinical assessment of critically ill patients who are commonly supine. (nih.gov)
  • Does the motor cortical control of the diaphragm 'bypass' the brain stem respiratory centres in man? (manchester.ac.uk)
  • To investigate this, we stimulated the motor cortex using transcranial magnetic stimulation (TMS) in six subjects at end-expiration (diaphragm relaxed) and during voluntary inspiration. (manchester.ac.uk)
  • The sizes of the evoked compound action potentials in the diaphragm and also, as a control, in the thumb were no different whether TMS was delivered during normocapnia or during hypocapnia (Pet(CO(2))=25 mmHg) when, presumably, the respiratory 'oscillator' was silent. (manchester.ac.uk)
  • Dive into the research topics of 'Does the motor cortical control of the diaphragm 'bypass' the brain stem respiratory centres in man? (manchester.ac.uk)
  • However, respiratory muscle recruitment and exercise-induced weakness is not fully described even in healthies. (ersjournals.com)
  • The thyrotropin-releasing hormone (TRH) analog taltirelin is of high pre-clinical interest given its neuronal-stimulant properties, minimal endocrine activity, tongue muscle activation following microperfusion into the hypoglossal motor nucleus (HMN) or systemic delivery, and high TRH receptor expression at the HMN compared to rest of the brain. (nature.com)
  • Hypoglossal nerve stimulation with an implanted device can help some people manage obstructive sleep apnea without a continuous positive airwave pressure (CPAP) machine. (hopkinsmedicine.org)
  • A hypoglossal nerve stimulation implant is an alternative for patients who cannot tolerate CPAP treatment. (hopkinsmedicine.org)
  • What is hypoglossal nerve stimulation? (hopkinsmedicine.org)
  • Hypoglossal nerve stimulation is a treatment for obstructive sleep apnea that uses an implant to stimulate a nerve under the tongue to prevent the tongue from blocking the airway. (hopkinsmedicine.org)
  • A hypoglossal nerve stimulation device sends a gentle electric pulse to a branch of the hypoglossal nerve. (hopkinsmedicine.org)
  • Hypoglossal nerve stimulation aims to improve breathing, treat upper airway obstruction and reduce snoring, gasping and choking so the person can have a more restful sleep. (hopkinsmedicine.org)
  • If you and your doctor think you may be a candidate for hypoglossal nerve stimulation, the next step is a drug-induced sleep endoscopy. (hopkinsmedicine.org)
  • Clinically, the order of loss of nerve function is as follows: (1) pain, (2) temperature, (3) touch, (4) proprioception, and (5) skeletal muscle tone. (nih.gov)
  • An electromyogram (EMG) showed normal sensory nerve function, low amplitude on motor stimulation, mild (10%) decremental response on repetitive low frequency, and incremental response on high-frequency nerve stimulation, consistent with botulism ( 13 ). (cdc.gov)
  • There was no difference in maximal workload and minute ventilation, with similar ventilatory muscle recruitment. (ersjournals.com)
  • Respiratory rate during quiet breathing decreased in all subjects when stimulated, whereas minute ventilation increased by 1.05-2.07 L/min. (iospress.com)
  • These include: (1) stimulation of the respiratory center, (2) increased minute ventilation, (3) decreased threshold to hypercapnia, (4) increased response to hypercapnia, (5) increased skeletal muscle tone, (6) decreased diaphragmatic fatigue, (7) increased metabolic rate, and (8) increased oxygen consumption. (drugs.com)
  • Sublethal doses of NA and HA produced marked depression of blood pressure, coronary dilation, and mild respiratory stimulation with variable convulsions. (cdc.gov)
  • Apparent central stimulation is manifested as restlessness, tremors and shivering progressing to convulsions, followed by depression and coma progressing ultimately to respiratory arrest. (nih.gov)
  • New UCLA research published in The Journal of Physiology points to a novel treatment for respiratory depression associated with opioid use that administers electrical pulses to the back of the neck, helping patients regain respiratory control following high dosage opioid use. (reachmd.com)
  • within 48 hours, the patient was quadriplegic with no voluntary muscle function or distal tendon reflexes. (cdc.gov)
  • Psilocybin had little effect on the cortical potentials elicited by stimulation of the reticular formation in the mesencephalon and the posterior hypothalamus. (erowid.org)
  • Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation method used worldwide to make causality-based inferences about brain-behavior interactions, assess cortical reactivity, and map functionally relevant. (medandlife.org)
  • The patient had respiratory arrest in the emergency department and was intubated. (cdc.gov)
  • Of these, 42 developed respiratory failure, and 25 of those who developed respiratory failure were referred to 9 high facility hospitals for treatment of severe respiratory failure and autonomic nervous system involvement. (nih.gov)
  • An increasing of mental alertness, shortening of reaction time, and improving efficiency of muscle action is brought about by caffeine's stimulation of the heart and respiratory system, bringing more oxygen to the brain. (holymtn.com)
  • Sniff and magnetic stimulation (Tw) were performed. (ersjournals.com)
  • This study reveals an alternative in-vivo approach by magnetic resonance imaging to visualise the muscle in the fossa pterygopalatina on 78 head halves, describe the connections with the musculus temporalis and pterygoïdeus lateralis as well as report the incidence without dealing with the known inconveniences of the dissection approach. (daneurope.org)
  • Respiratory muscle weakness can contribute to limit exercise. (ersjournals.com)
  • The bulbar muscles are affected most commonly and most severely, but most patients also develop some degree of fluctuating generalized weakness. (medscape.com)
  • Often within 1 year, patients have generalized symptoms such as weakness or fatigue and one third of patients develop respiratory weakness, requiring mechanical ventilation. (medscape.com)
  • The patient may also complain of a specific weakness of certain muscle groups (eg, those used when climbing stairs). (medscape.com)
  • The most successful rehabilitation programs are those in which services are provided by a respiratory or physical therapist, a nurse, a doctor, a psychologist or social worker, and a dietitian working as the pulmonary rehabilitation team to coordinate complex medical services. (merckmanuals.com)
  • Pulmonary venoarterial shunts and alveolar hypoventilation result in V/Q mismatch, which is probably the most important mechanism of gas exchange impairment in infants with respiratory failure due to various causes, including respiratory distress syndrome (RDS). (medscape.com)
  • Rotenone's toxicity in humans, animals, and fish is via inhibition of mitochondrial respiratory chain complex I, with cell death by apoptosis due to excess generation of free radicals. (merckvetmanual.com)
  • The projects with the London Respiratory Physiology group resulted in research publications with involvement in an impact case and the development of new intellectual property. (guysandstthomasevents.co.uk)
  • This study aims to evaluate the feasibility and effectiveness of a novel abdominal FES system which generates stimulation automatically, synchronised with the subjects' voluntary breathing activity. (iospress.com)
  • We compared spirometry during unassisted and FES-assisted quiet breathing and coughing, and measured the effect of stimulation on end-tidal CO2 (EtCO2) during quiet breathing. (iospress.com)
  • The automatic stimulation system augmented spontaneous breathing and coughing in tetraplegic patients and may provide a potential means of respiratory support for tetraplegic patients with reduced respiratory capacity. (iospress.com)
  • The respiratory system responds beneficially to breathing exercises which balance the parasympathetic/sympathetic nervous system. (positivehealth.com)
  • In a further six subjects, TMS was performed during relaxed spontaneous breathing at three different points in the respiratory cycle. (manchester.ac.uk)
  • EES administered at the cervical spinal cord, which is located at the back of the neck, activates a network of neurons in the brainstem that stimulates and coordinates respiratory muscles and improves the rate and depth of breathing. (reachmd.com)
  • Activation of these pathways is relayed to the central nervous system via respiratory muscle and vagal afferents, which are consequently interpreted by the individual in the context of the affective state, attention, and prior experience, resulting in the awareness of breathing. (samj.org.za)
  • His studies concluded in the PhD thesis on 'Sleep-Disordered Breathing and the Respiratory Muscles' at King's College London. (guysandstthomasevents.co.uk)
  • If the infant is not breathing, the respiratory score is 0. (medlineplus.gov)
  • The primary objective of assisted ventilation is to support breathing until the patient's respiratory efforts are sufficient. (medscape.com)
  • METHODS: Fatigue was induced in a small hand muscle (abductor pollicis brevis) (n = 11). (daneurope.org)
  • Objective: This paper describes the state of the art, scientific publications, and ongoing research related to the methods of analysis of respiratory sounds. (medandlife.org)
  • We investigate the mechanisms of a range of conditions/diseases which affect skeletal muscle including fatigue, atrophy/hypertrophy, malignant hyperthermia, statin myopathy and heart failure, with a focus on the influence of physical activity, nutrition and drugs. (leeds.ac.uk)
  • The healing powers of water and the healthy air have been used for centuries to heal respiratory diseases. (eurohike.at)
  • There is enhanced circulation of oxygenated blood, strengthening of the heart muscles, and stimulation of the lymphatic system, boosting immunity. (positivehealth.com)
  • Irreversible pathological changes to airway smooth muscle cells (ASMCs) such as hyperplasia and hypertrophy can occur in asthmatic patients. (ersjournals.com)
  • Severe distortion of airway smooth muscle cells (ASMCs) is a common consequence of severe asthma [ 3 ]. (ersjournals.com)
  • This muscle relaxation, especially in people with an unusually narrow airway, can cause a partial or complete blockage of airflow during sleep. (hopkinsmedicine.org)
  • In immunocompromised patients, treatment of respiratory syncytial virus (RSV) and cytomegalovirus infections may be appropriate, especially if lower airway disease is suspected. (medscape.com)
  • Pharyngeal muscle activity and responsiveness are key pathophysiological traits in human obstructive sleep apnea (OSA) and strong contributors to improvements with pharmacotherapy. (nature.com)
  • A key component of OSA pathogenesis is the impact of sleep mechanisms on pharyngeal muscle tone and compensatory motor responses. (nature.com)
  • [ 1 ] The involvement of the facial muscles results in changes in expression and speech, whereas involvement of the pharyngeal muscles results in progressive difficulty with mastication and deglutition. (medscape.com)
  • The sympathetic system generally mobilizes bodily resources for action-it constricts visceral blood vessels so that more blood is directed to muscles and brain, accelerates the heart beat, inhibits intestinal and gastric activity, widens the pupils of the eye, and secretes adrenaline The parasympathetic system is the antagonist of these effects. (druglibrary.net)
  • In most cases this is muscarinic receptor stimulation, as the parasympathetic nervous system is particularly dependent on ACh regulation. (scielo.org.za)
  • Our research focuses on skeletal muscle structure and function using a range of approaches from assessment of fundamental molecular mechanisms that underlie excitation-contraction coupling through to whole-body functional measures that underpin muscle performance. (leeds.ac.uk)
  • In order to bring balance to tri-dosh vata, pitta, and kapha and empower our internal systems such as blood circulation, digestion, respiratory system, and defense the role of shatkarma, one cannot be ignored. (springeropen.com)
  • Added to this are the numerous physical benefits that hiking brings such as the support to our immune system, a mood-boosting effect, stimulation of the blood circulation and fat metabolism, strengthening of muscles and much more. (eurohike.at)
  • In the moderately severe stage, there was a low-amplitude compound muscle action potential with a low-rate incremented/high-rate decremented response. (nih.gov)
  • The physical effects include stimulation of digestive juice, the kidneys, and the metabolism in ways that possibly help eliminate toxins. (holymtn.com)
  • A change in scenery and physical activity is a form of positive mental stimulation. (utilitarian.net)
  • Smooth muscle inhibition, including inhibition of smooth muscle of the gut, bronchioles, and skeletal muscle vascular smooth muscle. (pharmacology2000.com)
  • Clinical signs were respiratory failure within 24 hours of symptom onset, complete or near complete quadriplegia by the fifth day, and neuromuscular recovery beginning on the eighth day. (cdc.gov)
  • The automatic stimulation system ensured that consistent stimulation was achieved. (iospress.com)
  • The system dependably recognised spontaneous respiratory effort, stimulating appropriately, and was well tolerated by patients. (iospress.com)
  • Our interests lie in the muscle itself, including blood vessels and fibre composition, as well as in the neural mechanisms and pathways through which the central nervous system and skeletal muscles communicate. (leeds.ac.uk)
  • Scientists do not fully understand what causes GBS, but it is believed that stimulation of the body's immune system may play a role in its development. (cdc.gov)
  • In the early recovery phase, there was a low-amplitude compound muscle action potential with low- and high-rate incremented response. (nih.gov)
  • Psilocybin (1.5, 2.0, 2.25 and 5 mg/kg i.v.) elicited mydriasis, increases in blood pressure and respiratory rate and transient bradycardia in the rabbit. (erowid.org)
  • Relaxation serves many functions, it releases the muscles, circulates glandular changes, rejuvenates and allows the emotional energies to settle and release all residual stress and tension. (positivehealth.com)
  • Therapy addressing specific symptoms is the mainstay for most upper respiratory infections (URIs). (medscape.com)
  • initially 85% of patients have involvement of the eyelids and extraocular muscles, resulting in ptosis and/or diplopia. (medscape.com)
  • Within 1-65 h after exposure, 18 of the patients with severe respiratory failure had become ill. (nih.gov)
  • This can cause respiratory failure, which can be fatal. (reachmd.com)
  • Ventilation may be required during immediate care of the infant who is depressed or apneic or during prolonged periods of respiratory failure treatment. (medscape.com)
  • diarrhea or respiratory illness. (cdc.gov)