• progenitor
  • $3.52 million Directing hES Derived Progenitor Cells into Musculoskeletal Lineages , David W. Rowe, principal investigator, UConn Health Center and UConn. (uconn.edu)
  • proliferation
  • Non-specific suppression of T cell proliferation is mediated by soluble factors such as transforming growth factor (TGF)-β, kynurenine, prostaglandin E2 (PGE2), nitric oxide, haem oxygenase products and insulin-like growth factor binding protein. (comparetrials.com)
  • MSCs
  • Recently, significant interactions between MSCs and cells from the immune system have been demonstrated:MSCs were found to downregulate T and B lymphocytes, natural killer cells (NK) and antigen presenting cells through various mechanisms, including cell-to-cell interaction and soluble factor production. (comparetrials.com)
  • MSCs can fully suppress T cell function which involves some degree of MSC activation or 'licensing' thought to involve interferon (IFN)-γ in conjunction with IL-1α, IL-1β or tumour necrosis factor-a. (comparetrials.com)
  • Mesenchymal Stem Cell Basal Medium, when supplemented with Mesenchymal Stem Cell Growth Kit for Adipose and Umbilical-derived MSCs - Low Serum (ATCC ® No. PCS-500-040) provides an ideal cell system to propagate mesenchymal stem cells in low serum (2% FBS) conditions. (atcc.org)
  • human
  • $2.5 million Human ES Cell Core at University of Connecticut and Wesleyan University , Ren-He Xu, principal investigator, UConn Health Center. (uconn.edu)
  • $880,000 SMAD4-based ChIP-chip Analysis to Screen Target Genes of BMP and TGF Signaling in Human ES Cells , Ren-He Xu, principal investigator, UConn Health Center. (uconn.edu)
  • $200,000 Pragmatic Assessment of Epigenetic Drift in Human ES Cell Lines , Theodore Rasmussen, principal investigator, Department of Animal Science. (uconn.edu)
  • The maintenance medium for human pluripotent stem cells according to the present invention includes xylose as a saccharide. (patentsencyclopedia.com)
  • 6. The method according to claim 1, wherein the maintenance medium is a culture medium for human iPS cells containing xylose in place of glucose. (patentsencyclopedia.com)
  • 7. The method according to claim 6, wherein the basal medium of a culture medium for human iPS cells is a DMEM/F12 medium. (patentsencyclopedia.com)
  • In order to grow human ES cells or human iPS cells while maintaining the undifferentiation status and the pluripotency, it is usually needed to culture these cells in coexistence with feeder cells, or to add substances for maintaining undifferentiation status, for example, ascorbic acid, basic fibroblast growth factor (bFGF), and transforming growth factor β-3 (TGF-β3), to a medium (refer to WO 2011/058558). (patentsencyclopedia.com)
  • For human ES cells and iPS cells, it is recommended to change a medium every day due to their fast metabolism, and the risk of contamination is high, placing a burden on researchers. (patentsencyclopedia.com)
  • It is best to use caution when handling any human cells. (atcc.org)
  • We recommend that all human cells be accorded the same level of biosafety consideration as cells known to carry HIV. (atcc.org)
  • ethical
  • Last month, a separate group of scientists conducted a peer review evaluating all the applications, and ranked each proposal for the state stem cell panel with respect to ethical and scientific merit. (uconn.edu)
  • research
  • The disbursements are the first made under Connecticut's 10-year, $100 million commitment to fund stem cell research, as authorized by Gov. M. Jodi Rell and the General Assembly in 2005. (uconn.edu)
  • Eight Connecticut-based universities and non-profit institutes submitted 70 research proposals totaling $65 million to the state stem cell panel. (uconn.edu)
  • The plan calls for $1 billion in research funding (about half for work on stem cells) and the creation of a post for a science and technology director. (scienceblogs.com)
  • System
  • $200,000 Quantitative Analysis of Molecular Transport and Population Kinetics of Stem Cell Cultivation in a Microfluidic System , Tai-Hsi Fan, principal investigator, Department of Mechanical Engineering. (uconn.edu)
  • medium
  • Thus, cryopreservation is usually performed if the properties are maintained consistently, i.e., cells are preserved, for a medium and long term. (patentsencyclopedia.com)
  • center
  • $200,000 Cell Cycle and Nuclear Reprogramming by Somatic Cell Fusion , Winfried Krueger, principal investigator, UConn Health Center. (uconn.edu)