The first clinical trials involving a patient receiving human embryonic stem cells began in October 2010 at the Shepard Center, a spinal cord injury hospital in Atlanta. (cbc.ca)
Scientists say embryonic stem cells are the most useful type because they have the potential to become any type of cell within the body. (cbc.ca)
However, researchers at the Harvard Stem Cell Institute say reprogrammed cells won't eliminate the need or value of studying embryonic stem cells. (cbc.ca)
The creation of an embryo by nuclear transfer is a human being whose right to continued life should be respected. (cmq.org.uk)
is a British developmental biologist who was the first to use nuclear transfer of differentiated adult cells to generate a mammalian clone, a Finn Dorset sheep named Dolly, born in 1996. (mathisfunforum.com)
Genetically5
Applications such as the construction of genetically modified and cloned animals, and the studies on gene and cell development are becoming more prevalent. (rwdstco.com)
Substances such as DNA and RNA are introduced into the developing embryo through microinjection techniques, providing researchers with the fastest and most reliable means to the preparation of genetically modified or mutated zebrafish species. (rwdstco.com)
They are widely used in research fields including genetics, evolutionary biology and developmental biology, especially the creation of different genetically modified species. (rwdstco.com)
The lamb's cloning was the first time scientists were able to coax a mature adult cell into behaving like a cell from a newly fertilized embryo in order to create a genetically identical animal. (wgnradio.com)
Dolly's creation was part of a broader project by scientists to create genetically modified sheep that could produce therapeutic proteins in their milk. (wgnradio.com)
Gene1
The Edinburgh Mouse Atlas, also called the e-Mouse Atlas Project (EMAP), is an online resource comprised of the e-Mouse Atlas (EMA), a detailed digital model of mouse development, and the e-Mouse Atlas of Gene Expression (EMAGE), a database that identifies sites of gene expression in mouse embryos. (asu.edu)
Researchers2
Researchers there are working on technology that induces human skin cells to change into the kind of stem cells that have been created by embryos. (cbc.ca)
The researchers merely place the stem cells in a matrix in appropriate conditions, then stand back and watch them do it. (frogheart.ca)
Adult tissues2
This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues, such as a patient's own skin cells,' said principal author Andras Nagy, senior investigator at Mount Sinai's Samuel Lunenfeld Research Institute. (cbc.ca)
Stem cells from cord blood or adult tissues do not give rise to the same moral considerations as those derived from embryos or cloned embryos or aborted foetuses. (cmq.org.uk)
Development9
They are in an early stage of development and have the ability to become any type of cell to form skin, bones, organs or other body parts. (cbc.ca)
The principles of stem cell development and differentiation should be researched in animals. (cmq.org.uk)
Recording and contextualizing the science of embryos, development, and reproduction. (asu.edu)
Xenopus embryos are commonly used in researches such as studying the effects of the nervous system on cell level and investigating how the nerve development forms the correct links. (rwdstco.com)
Being important models for the research of embryo development, they have other advantages such as high tolerance to different types of surgical intervention and external breeding. (rwdstco.com)
Therefore, Xenopus embryos have become significant and unique resources for the research of early embryo development and cell biology. (rwdstco.com)
So why are editors giving that name to stem cell-based models of human development? (frogheart.ca)
To claim that the fundamental stages of embryo development that we learnt at school - fertilisation, cleavage and compaction - could now be bypassed to achieve the same result would be wrong. (frogheart.ca)
While these models can replicate aspects of the early-stage development of human embryos, they cannot and will not develop to the equivalent of postnatal stage humans. (frogheart.ca)
Wilmut5
Ian Wilmut, the cloning pioneer whose research was critical to the creation of Dolly the Sheep, has died, the Roslin Institute at the University of Edinburgh said Monday. (wgnradio.com)
LONDON (AP) - Ian Wilmut, the cloning pioneer whose work was critical to the creation of Dolly the Sheep in 1996, has died at age 79. (wgnradio.com)
Wilmut set off a global discussion about the ethics of cloning when he announced that his team at the university's Roslin Institute for animal biosciences had cloned a lamb using the nucleus of a cell from an adult sheep. (wgnradio.com)
Wilmut, a trained embryologist, later focused on using cloning techniques to make stem cells that could be used in regenerative medicine. (wgnradio.com)
Whitelaw described Wilmut as a "titan" of science and said his work in Dolly's creation transformed scientific thinking at the time. (wgnradio.com)
Moral3
Some argue that the possibility of mimicking stem cells without acquiring them from embryos, side-steps that moral dilemma. (cbc.ca)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
The Donaldson Report is, however, wrong in bracketing all stem cells together as if there were no moral issues concerning their origins. (cmq.org.uk)
Human10
Opponents argue that any embryo has the potential to develop into a mature human. (cbc.ca)
In a study published in the online journal Nature on March 1, 2009, Canadian researches described a new method for generating stem cells from adult human tissue. (cbc.ca)
Secondly, widening the scope of research further establishes the human embryo as a mere commodity for use as a research animal and moves away from Dame Warnock's assertion that the embryo deserves special respect. (cmq.org.uk)
Most of the differences between Britain and other countries are due to the lowly status that is afforded the human embryos in this country. (cmq.org.uk)
Britain is almost isolated in Europe in its failure to afford the human embryo any meaningful status, as attested by the huge number of embryos produced and destroyed. (cmq.org.uk)
Science, supported by the human genome project has already shown that many of the basic 'cell control' processes are common across a wide range within both animal and plant kingdoms. (cmq.org.uk)
The year after Dolly's creation, U.S. President Bill Clinton imposed a ban on the use of federal funds for human cloning but stopped short of banning all cloning research. (wgnradio.com)
Further, the ISSCR Guidelines prohibit the transfer of any embryo model to the uterus of a human or an animal. (frogheart.ca)
Suggestions that any of the current in vitro models can recapitulate an intact embryo, human sentience or integrated brain function are unfounded overstatements that should be avoided and contradicted with more precise characterizations of current understanding. (frogheart.ca)
Science2
In December 1999, the editors of Science, the journal devoted to scientific and medical matters, called stem cell research the 'Breakthrough of the Year. (cbc.ca)
These animals are important in terms of their significance to science and the ethical issues that their creation raises. (wikiquote.org)
Early-stage1
Moreover, most early-stage embryos that are produced naturally (that is, through the union of egg and sperm resulting from sexual intercourse) fail to implant and are therefore wasted or destroyed. (wikiquote.org)
Create3
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
The President may bind the U.S. to international treaties and executive agreements that require creation of domestic laws, or that create law that is on par with federal statutes.4 N Legislation. (studylib.net)
Unlike some recent media reports describing this research, the ISSCR advises against using the term "synthetic embryo" to describe embryo models, because it is inaccurate and can create confusion. (frogheart.ca)
Forms2
Some forms of stem cell research such as the use of cells from adults or cord blood, are not controversial. (cmq.org.uk)
On the topic of cloning we should set an example by outlawing it in all its forms, cloned babies and so called 'therapeutic cloning' (which is a misnomer as at this stage no therapeutic benefit will result from the cloned embryo). (cmq.org.uk)
Scientists4
Scientists have been all abuzz in the last few years over stem cells - cellular magicians that promise to dazzle and amaze. (cbc.ca)
Scientists are fascinated by the ability of stem cells to become any type of cell. (cbc.ca)
While Dolly's creation was heralded as a revolution by some scientists, it unnerved many, with critics calling such experiments unethical. (wgnradio.com)
Dolly's creation prompted other scientists to clone animals including dogs, cats, horses and bulls. (wgnradio.com)
Models2
Integrated embryo models are neither synthetic nor embryos. (frogheart.ca)
While organoids, chimeras, embryo models, and other stem cell-based models are useful research tools offering possibilities for further scientific progress, limitations on the current state of scientific knowledge and regulatory constraints must be clearly explained in any communications with the public or media. (frogheart.ca)
Order3
The purpose of PGD is to identify what are considered to be abnormal embryos in order to select the most desirable embryos for implantation. (asu.edu)
With a microinjection system, the super small and thin microinjection glass capillary needle (also known as glass electrode) is used for implanting exogenous materials (DNA or RNA or cell) into the cells, leading to the occurrence of chimerism between exogenous materials and genomes in order to integrate the exogenous materials into the genome. (rwdstco.com)
Usually, there's a rough chronological order to how I introduce the research, but this time I'm looking at the term used to describe it, following up with the various news releases and commentaries about the research, and finishing with a Canadian perspective. (frogheart.ca)
Intact1
If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)
Animal1
This time lag would allow for breakdown of the cells, which normally happens when any animal dies. (wikiquote.org)
Potential2
They are still developing and they have the potential to become any of the major specialized cell types within that organ. (cbc.ca)
What are the potential medical benefits of stem cell research 9 what is the most likely time scale for realising them? (cmq.org.uk)
Species1
Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
Time1
In 1902, Dr. Barber used this method to separate the bacterial cells, and at the same time developed the first set of microinjection instruments. (rwdstco.com)
Attention1
Would issues relating to research on embryos benefit from more attention at international level? (cmq.org.uk)
Kind1
The second is getting the right kind of cells. (wikiquote.org)
Medical1
Duncan Davidson and Richard Baldock founded the project in 1992, and the Medical Research Council (MRC) in Edinburgh, United Kingdom, funds the project. (asu.edu)
Years1
Although this was the ISSCR's first attempt to put that position to the public , it had already made that recommendation to the research community two years previously. (frogheart.ca)
University1
In 1966, his final year at Nottingham, he received a scholarship to conduct research for a summer under English biologist Ernest John Christopher Polge in the Unit of Reproductive Physiology and Biochemistry, then a division of the Agricultural Research Council at the University of Cambridge. (mathisfunforum.com)
Debate1
But there has been intense debate over the use of stem cells. (cbc.ca)
Body1
His work was critical to research that aims to treat genetic and degenerative diseases by helping the body repair damaged tissue. (wgnradio.com)