Germ-Line MutationStem CellsLi-Fraumeni SyndromeMutation, MissenseMutationDNA Mutational AnalysisPedigreeGenes, p53Polymerase Chain ReactionHeterozygoteGenetic Predisposition to DiseasePoint MutationBase SequenceMolecular Sequence DataStem Cell TransplantationHematopoietic Stem CellsEmbryonic Stem CellsMicrosatellite RepeatsAdult Stem CellsGenotypePluripotent Stem CellsBreast NeoplasmsGerm CellsCell LineCell DifferentiationHematopoietic Stem Cell TransplantationStem Cell NicheInduced Pluripotent Stem CellsNeural Stem CellsMultipotent Stem CellsMesenchymal Stem Cell TransplantationFrameshift MutationStem Cell FactorNeoplasms, Germ Cell and EmbryonalMesenchymal Stromal CellsCell LineageCell Line, TumorCells, CulturedCell ProliferationPhenotypeTestisSpermatogoniaGene Expression Regulation, DevelopmentalSpermatogenesisStem Cell ResearchAmino Acid SequencePlant StemsFetal Stem CellsRNA, MessengerSignal TransductionTranscription FactorsExonsAllelesMice, Inbred C57BLGonadsOctamer Transcription Factor-3Germ LayersEmbryo, MammalianMice, TransgenicReverse Transcriptase Polymerase Chain ReactionNeoplastic Stem CellsDNA-Binding ProteinsGene Expression RegulationHematopoietic Stem Cell MobilizationMutation RateDNA PrimersBone Marrow CellsWheat Germ AgglutininsOogenesisCell Culture TechniquesDrosophila melanogasterAmino Acid SubstitutionTranscription, GeneticCaenorhabditis elegansSpermatozoaImmunohistochemistryGene ExpressionTotipotent Stem CellsHomozygoteSequence Analysis, DNAFlow CytometryRegenerationCell Line, TransformedModels, BiologicalMutagenesisDNAChimeraCell SeparationPromoter Regions, GeneticDrosophila ProteinsTransfectionNuclear ProteinsGene Expression ProfilingHomeodomain ProteinsDrosophilaPolymorphism, Single-Stranded ConformationalCloning, MolecularCell SurvivalCaenorhabditis elegans ProteinsTime Factors