• vitro
  • For the current clinical treatment, the expansion of cells in vitro has been a promising alternative method for the bone tissue engineering strategy. (nus.edu.sg)
  • and 3) for the bioreactors application, cell seeding method can play a significant role supporting the progress of the in vitro cell culture. (nus.edu.sg)
  • In vitro, in the presence of VEGF(165), hAC133(+) cells only adopted a venous and microvascular EC phenotype, while hMAPCs differentiated into both arterial and venous ECs, possibly because hMAPCs expressed significantly more sonic hedgehog (Shh) and its receptors as well as Notch 1 and 3 receptors and some of their ligands. (cun.es)
  • These results represent the first demonstration of adult stem cells with the potential to be differentiated into different types of ECs in vitro and in vivo and provide a useful human model to study arteriovenous specification. (cun.es)