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CarcinomaCarcinoma, Squamous CellCarcinoma, HepatocellularCarcinoma in SituCarcinoma, PapillaryLiver NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Basal CellImmunohistochemistryCarcinoma, Transitional CellNutritional StatusTumor Markers, BiologicalCarcinoma, Intraductal, NoninfiltratingPrognosisCarcinoma, BronchogenicBreast NeoplasmsCarcinoma, Adenoid CysticAdenocarcinomaCarcinoma, Small CellCarcinoma, MedullaryCarcinoma, LobularNeoplasm StagingCell Line, TumorNeoplasm InvasivenessCarcinoma, NeuroendocrineNasopharyngeal NeoplasmsGene Expression Regulation, NeoplasticThyroid NeoplasmsLung NeoplasmsHealth StatusTumor Cells, CulturedCarcinoma, AdenosquamousCarcinoma, MucoepidermoidHead and Neck NeoplasmsCarcinoma, EndometrioidLymphatic MetastasisEsophageal NeoplasmsMouth NeoplasmsCarcinoma, DuctalCarcinoma, EmbryonalRetrospective StudiesCarcinoma, Merkel CellOvarian NeoplasmsStatus EpilepticusColonic NeoplasmsTreatment OutcomeNeoplasm MetastasisAdrenocortical CarcinomaCarcinoma, VerrucousNeoplasm Recurrence, LocalCarcinoma, Signet Ring CellNeoplasm ProteinsStomach NeoplasmsUrinary Bladder NeoplasmsSkin NeoplasmsSurvival RateSurvival AnalysisDNA, NeoplasmAntineoplastic AgentsMice, NudeRNA, MessengerCarcinoma, Large CellUterine Cervical NeoplasmsImmunoenzyme TechniquesLaryngeal NeoplasmsTime FactorsFollow-Up StudiesNeoplasm TransplantationRisk FactorsReverse Transcriptase Polymerase Chain ReactionNeoplasms, Multiple PrimaryTumor Suppressor Protein p53Disease ProgressionAdenocarcinoma, FollicularColorectal NeoplasmsCarcinoma, Non-Small-Cell LungAdenocarcinoma, MucinousAntigens, NeoplasmPrecancerous ConditionsEmbryonal Carcinoma Stem CellsCell ProliferationEndometrial NeoplasmsCombined Modality TherapyDisease-Free SurvivalApoptosisGallbladder NeoplasmsCarcinoma, Papillary, FollicularMutationAdenocarcinoma, Clear CellPancreatic Neoplasmsalpha-FetoproteinsTongue NeoplasmsCystadenocarcinoma, SerousEducational StatusCase-Control StudiesTissue Array AnalysisCell DivisionCisplatinCarcinoma, Lewis LungKaplan-Meier Estimate
Squamous cell carcinomasRenal Cell CarcArchived tumorNasopharyngeal carcinomaDuctalSituPatientsOropharyngeal squamous cell carcCutaneous squamous cell carcHead and NeckCancerColorectal carcinomaUrothelial carcinomaAdrenocortical carcinomaEpidermal growth fNeoplasmMalignancyLenvatinibOncologyPancreasOutcomeCervixHistologyMetastasesCirrhosisIntraductalTreatmentCervicalFallopianEGFRClinicalLungProgressionRecurrenceHuman papillomavirusSurvival
Squamous cell carcinomas10
  • Base of tongue squamous cell carcinomas, outcome depending on treatment strategy and p16 status. (lu.se)
  • Although head and neck cancers include multiple histologies and primary sites, squamous cell carcinomas (SCC) originating in the oropharynx, oral cavity, larynx, or hypopharynx are the most common. (ascopost.com)
  • The aim of this study was to analyse EGFR expression, EGFR gene copy number and EGFR and K-RAS mutations in two cohorts of squamous cell carcinomas, specifically anal canal and tonsil carcinomas. (biomedcentral.com)
  • EGFR immunoreactivity was present in 36/43 (83.7%) of anal canal and in 20/24 (83.3%) of tonsil squamous cell carcinomas. (biomedcentral.com)
  • BACKGROUND AND PURPOSE: Patients with human papillomavirus-positive oropharyngeal squamous cell carcinomas have a better survival rate than those with human papillomavirus-negative oropharyngeal squamous cell carcinomas. (vu.nl)
  • MATERIALS AND METHODS: Forty-four patients with oropharyngeal squamous cell carcinomas underwent pretreatment DWI. (vu.nl)
  • CONCLUSIONS: No significant association between ADC and human papillomavirus status was found in oropharyngeal squamous cell carcinomas. (vu.nl)
  • In our study population, differences in genetic and histologic features between human papillomavirus-positive and human papillomavirus-negative oropharyngeal squamous cell carcinomas did not translate into different ADC values. (vu.nl)
  • We explored whether human papillomavirus status and ADC values are independent tumor characteristics.MATERIALS AND METHODS: Forty-four patients with oropharyngeal squamous cell carcinomas underwent pretreatment DWI. (vu.nl)
  • HPV infection has been reported to correlate with several cancer types, especially squamous cell carcinomas. (biochain.com)
Renal Cell Carc9
  • Assistance with the prescription drugs and biologics used in the treatment of renal cell carcinoma. (healthwellfoundation.org)
  • 1. You are being treated for Renal Cell Carcinoma. (healthwellfoundation.org)
  • The most common renal cell carcinoma that develops in patients with end-stage renal disease and acquired cystic disease. (cismef.org)
  • Background: Renal cell carcinoma (RCC) is twice as common among men compared with women, and hormonal factors have been suggested to partially explain this difference. (lu.se)
  • Metastatic renal cell carcinoma (mRCC) accounts for one-third of all newly diagnosed renal cell cancers. (mdpi.com)
  • The optimal follow-up (FU) strategy for patients treated for localised renal cell carcinoma (RCC) remains unclear. (lu.se)
  • Treatment protocols for renal cell carcinoma are provided below, including treatment of localized and advanced disease and recommendations for patients with predominantly clear cell carcinoma and those with predominantly non-clear cell carcinoma. (medscape.com)
  • The therapeutic approach for renal cell carcinoma is guided by the probability of cure, which is related directly to the stage or degree of tumor dissemination. (medscape.com)
  • See Renal Cell Carcinoma: Recognition and Follow-up , a Critical Images slideshow, to help evaluate renal masses and determine when and what type of follow-up is necessary. (medscape.com)
Archived tumor1
  • Data on p16 status were updated or completed with immunohistochemical analysis of archived tumor material. (lu.se)
Nasopharyngeal carcinoma7
  • The purpose of this trial is to explore whether concurrent chemoradiotherapy is not inferior to induction chemotherapy combined with concurrent chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma. (centerwatch.com)
  • Lymphoepithelioma-like carcinoma (LELC) is a medical term referring to a histological variant of malignant tumor arising from the uncontrolled mitosis of transformed cells originating in epithelial tissue (or in cells that display epithelial characteristics) that bear microscopic resemblance to lymphoepithelioma (nasopharyngeal carcinoma). (wikipedia.org)
  • To describe the clinical characteristics of the patients who suffered from relapse after conventional irradiation for nasopharyngeal carcinoma (NPC). (hindawi.com)
  • Most recurrent nasopharyngeal carcinoma is advanced disease. (hindawi.com)
  • Nasopharyngeal carcinoma (NPC) is a common malignancy in Southern China. (hindawi.com)
  • Treatment results for nasopharyngeal carcinoma have improved in the past two decades. (hindawi.com)
  • Although immune checkpoint inhibitors have opened a new mode of treatment for solid tumors, their efficacy in nasopharyngeal carcinoma (NPC) needs to be further investigated. (jcancer.org)
Ductal4
Situ3
  • The EGFR gene status and protein expression were investigated by direct DNA sequencing of the hot-spot regions in exons 18, 19 and 21, fluorescence in situ hybridisation (FISH), and immunohistochemistry in tumour tissues from 23 patients with ATC. (bmj.com)
  • Testicular germ cell cancers in young adult men derive from a precursor lesion called carcinoma in situ (CIS) of the testis. (ku.dk)
  • Lobular carcinoma in situ (LCIS), which is not considered a malignancy, arises from the lobule at the terminal end of the duct and shows a rather diffuse distribution throughout the breast, which explains its presentation as a nonpalpable mass in most cases (see the images below). (medscape.com)
Patients13
  • This has important clinical implications as, in contrast to advanced-stage NSCLC, chemotherapy can also be offered to patients with SCLC and a poor or bad performance status (World Health Organization performance status of 2-3), since a rapid amelioration of the patient's symptoms and general condition can be expected together with an improved outcome 7 . (ersjournals.com)
  • However, the risk of toxicity is greater in this group than in patients with good performance status. (ersjournals.com)
  • Additionally, there is recurrent and/or metastatic head and neck SCC (HNSCC), where all systemic therapy is palliative, regardless of HPV status, and there continues to be a great need for improvement in outcomes for all patients. (ascopost.com)
  • HPV-positive oropharyngeal cancer has a significantly better prognosis, with clinical risk stratification by smoking status and stage used to identify patients with low-risk cancer and intermediate-risk cancer. (ascopost.com)
  • Knowledge of the expression, amplification and mutation status of EGFR as well as downstream effectors such as K-RAS would help us to better understand the response of cancer patients to molecular targeted therapy. (biomedcentral.com)
  • To evaluate the effectiveness of transarterial chemoembolization (TACE) combined with lenvatinib and sintilimab in treating patients with midstage hepatocellular carcinoma (HCC). (hindawi.com)
  • TACE combined with lenvatinib and sintilimab in the treatment of Barcelona Clinic Liver Cancer (BCLC) stage B hepatocellular carcinoma can effectively control the tumor progression and prolong the survival time of patients. (hindawi.com)
  • FORT-2 is designed to evaluate safety, efficacy, RP2D and PK of rogaratinib in combination with atezolizumab in patients with untreated FGFR-positive urothelial carcinoma. (bcan.org)
  • The primary objective of the Part B is to compare progression-free survival (PFS) according to RECIST v1.1 of rogaratinib in combination with atezolizumab over placebo in combination with atezolizumab in untreated patients with FGFR-positive locally advanced or metastatic urothelial carcinoma. (bcan.org)
  • Patients with hepatocellular carcinoma (HCC) from nine hepatobiliary medical centers who underwent R0 resection were included. (bvsalud.org)
  • Obtaining negative margins for patients undergoing breast-conserving surgery (BCS) for invasive lobular carcinoma (ILC) can be difficult because of the unique histologic pattern of ILC. (nih.gov)
  • ABSTRACT The study's objective was to evaluate the clinical significance of sCD40L in HCV- associated hepatocellular carcinoma (HCV-HCC) patients. (who.int)
  • Les concentrations sériques de sCD40L circulant et d'interleukine 10 circulante ont été analysées à l'aide de la méthode immuno-enzymatique chez 30 patients positifs pour le VHC avec un CHC, chez 30 patients patients positifs pour le VHC avec une cirrhose du foie, et chez 30 volontaires d'âge correspondant en bonne santé avec des anticorps anti-VHC négatifs servant de groupe témoin. (who.int)
Oropharyngeal squamous cell carc2
  • A growing body of research shows that human papillomavirus (HPV) is a common and increasing cause of oropharyngeal squamous cell carcinoma (OSCC). (cdc.gov)
  • We focus on the role of HPV in the increased incidence of oropharyngeal squamous cell carcinoma (OSCC), the head and neck cancer in which HPV is most commonly found ( 4 ). (cdc.gov)
Cutaneous squamous cell carc3
  • Background: Surgical excision is the gold standard for cutaneous squamous cell carcinoma (cSCC), however its application is limited in specific cases. (uzh.ch)
  • Appearing as part of the journal's Gems series, the review examines the role of cutaneous beta HPVs in the development of cutaneous squamous cell carcinoma. (who.int)
  • Evidence indicates that beta HPVs, together with ultraviolet (UV) radiation, contribute to the development of cutaneous squamous cell carcinoma, by facilitating the accumulation of UV-induced DNA mutations. (who.int)
Head and Neck6
  • Advanced head and neck squamous cell carcinoma (HNSCC) is treated with radiotherapy, chemotherapy, targeted therapy or a combination of these treatments. (researchsquare.com)
  • With the availability of effective anti-EGFR therapies for various solid malignancies, such as non-cell small lung cancer, colorectal cancer and squamous cell carcinoma of the head and neck, the knowledge of EGFR and K-RAS status becomes clinically important. (biomedcentral.com)
  • Epidermal growth factor receptor (EGFR) has been validated as a therapeutic target in several human tumours, including colorectal cancer (CRC), non-small cell lung cancer (NSCLC) and squamous cell carcinoma of the head and neck (HNSCC). (biomedcentral.com)
  • Cases without a numeric score, non-squamous cell carcinoma primary tumors, and primary squamous cell carcinoma outside the head and neck were excluded. (ajnr.org)
  • Population differences influence human papillomavirus associated head and neck squamous cell carcinoma outcomes: a case of non-Western population. (irb.hr)
  • Head and neck cancer most commonly is of the squamous cell carcinoma type (HNSCC) and includes cancers of the oral cavity, oropharynx, hypopharynx, larynx, sinonasal tract, and nasopharynx. (cdc.gov)
Cancer6
  • Hepatocellular carcinoma (HCC), the most common primary liver cancer, is a highly lethal disease that causes ~700,000 mortalities worldwide each year ( 1 ). (spandidos-publications.com)
  • Irrespective of HPV status, however, smokers did have poorer overall survival than never-smokers, presumably due to effects of smoking that are unrelated to the primary cancer. (edu.au)
  • They also show that families with the CDKN2A 113insArg mutation have an increased risk not only of multiple melanomas and pancreatic carcinoma but also of breast cancer. (lu.se)
  • Hepatitis and hepatocellular carcinoma : novel approaches : joint conference of the National Health Research Institutes (NHRI) and American Association for Cancer Research (AACR) in conjuction with 4th TCOG annual meeting. (who.int)
  • Women with low-grade DCIS are at higher risk of developing invasive breast cancer than women without DCIS, but are less likely to have a recurrence of the breast carcinoma or to develop new cancers than women with higher-grade DCIS. (medscape.com)
  • Laryngeal Cancer Ninety percent of laryngeal cancer is squamous cell carcinoma. (msdmanuals.com)
Colorectal carcinoma1
  • Purpose: The extent to which the developmental transcription factor SOX9 functions as an oncogene or tumor suppressor in colorectal carcinoma (CRC) is debatable. (oncotarget.com)
Urothelial carcinoma1
  • No prior systemic treatment for locally advanced or metastatic urothelial carcinoma. (bcan.org)
Adrenocortical carcinoma1
Epidermal growth f1
  • The epidermal growth factor receptor (EGFR) has been reported to be overexpressed in anaplastic thyroid carcinoma (ATC). (bmj.com)
Neoplasm2
  • Hepatocellular carcinoma (HCC) is the sixth most commonly diagnosed and fourth most lethal neoplasm worldwide. (hindawi.com)
  • Extrapulmonary small-cell carcinoma (SCC) is a rare neoplasm that shares certain features with its pulmonary counterpart and occurs predominantly in the gastrointestinal tract (GIT). (mdpi.com)
Malignancy1
  • Hepatocellular carcinoma (HCC) is primarily a malignancy of the liver, advancing from a damaged, cirrhotic liver to HCC. (wjgnet.com)
Lenvatinib1
  • The purpose of this study is to see if treatment with both lenvatinib and pembrolizumab is effective for advanced adenoid cystic carcinoma (ACC) and other salivary gland cancers that have come back and/or spread to other parts of the body. (mskcc.org)
Oncology1
  • Eastern Cooperative Oncology Group Performance Status (ECOG PS) 0 or 1. (bcan.org)
Pancreas1
  • No significant differences were found in the survival from tumours largely refractive to therapy, e.g., carcinomas of the pancreas, lung and liver. (who.int)
Outcome1
  • Besides the HPV status, no adequate biomarkers have been found so far to predict the poor/good clinical outcome nor is the mechanism of how HPV modulates therapy response fully understood. (irb.hr)
Cervix1
  • Using Diacarta's QuantiVirus™ HPV E6/E7 RNA test, BioChain offers HPV-characterized H&N and cervix squamous cell carcinoma tissue sections from various donors as control. (biochain.com)
Histology1
  • With hepatocellular carcinoma, verified by histology/cytology, which is not amenable to curative treatment or transplantation. (knowcancer.com)
Metastases1
  • Animal models that mimic osteoblastic metastases associated with prostate carcinoma are required to improve the therapeutic options in humans. (whiterose.ac.uk)
Cirrhosis3
  • Electroencephalography may be helpful in the initial workup of a patient with cirrhosis and altered mental status, when ruling out seizure activity may be necessary. (medscape.com)
  • HBV leads to an estimated 5,000 deaths annually in the United States from cirrhosis of the liver and hepatocellular carcinoma. (cdc.gov)
  • Infection with HBV results in a wide spectrum of acute and chronic liver diseases that may lead to cirrhosis and hepatocellular carcinoma. (cdc.gov)
Intraductal2
Treatment2
  • During every followup visit, disease status and treatment toxicity were assessed. (hindawi.com)
  • Unfortunately, most people with chronic viral hepatitis are not aware of their status and do not receive appropriate treatment. (who.int)
Cervical1
  • High-risk genotypes 16 and 18 are associated with 70% of cervical and ~ 80% HPV positive cases are related to vulval and vaginal carcinoma. (biochain.com)
Fallopian1
  • The response rate to checkpoint inhibitors for women with high-grade serous carcinoma of the ovary, fallopian tube, and peritoneum (HGSC) is modest, and development of predictive biomarkers is needed. (lu.se)
EGFR4
  • The somatic status of the EGFR gene was investigated by PCR using primers specific for exons 18 through 21. (biomedcentral.com)
  • EGFR mutations were absent from squamous cell carcinoma of the anus and tonsils, but EGFR protein expression was detected in the majority of the cases. (biomedcentral.com)
  • EGFR amplification was seen in tonsil but not in anal canal carcinomas. (biomedcentral.com)
  • This indicates that EGFR and K-RAS mutation analysis is not useful as a screening test for sensitivity to anti-EGFR therapy in anal canal and tonsil squamous cell carcinoma. (biomedcentral.com)
Clinical3
  • Adrenocortical carcinomas (ACs) are uncommon malignancies that can have protean clinical manifestations. (medscape.com)
  • The goal of this study is to use computational pathology to help guide the development of human-based prognostic H&E biomarker(s) suitable for research and potential clinical use in lung squamous cell carcinoma (SCC). (uzh.ch)
  • We constructed adjusted staging systems with the BDI status, improved their predictive performance and facilitate clinical use. (bvsalud.org)
Lung1
  • There is considerable variation in the classification of LELC-while it is perhaps most commonly considered a subtype of squamous cell carcinoma, it can also be classified as a form of large cell carcinoma (i.e. when occurring in the lung), and can be considered as a separate, unique entity. (wikipedia.org)
Progression1
  • Hepatocyte growth factor (HGF) signaling through its receptor Met has been implicated in hepatocellular carcinoma tumorigenesis and progression. (ebi.ac.uk)
Recurrence1
  • The effect of smoking on loco-regional recurrence and disease specific survival outcomes was not statistically significant, nor was there significant evidence that the effect of smoking status on these outcomes was modified by HPV status. (edu.au)
Human papillomavirus3
  • We explored whether human papillomavirus status and ADC values are independent tumor characteristics. (vu.nl)
  • Human papillomavirus status was determined with p16 immunostaining, followed by high-risk human papillomavirus DNA detection on the p16-positive cases. (vu.nl)
  • Long-term follow-up studies are needed to establish whether ADC has prognostic value and whether this is independent of the human papillomavirus status. (vu.nl)
Survival1
  • Smoking status was a significant predictor of overall survival (p = 0.04). (edu.au)