• Clinical outcome measures were assessed on admission and at discharge by using the National Institutes of Health Stroke Scale as well as 3 months after treatment by using the modified Rankin Scale. (ajnr.org)
  • Times to onset of improvements greater than or equal to minimum clinically important differences (MCIDs) in pain as a determinant of clinical outcomes at week 24 were compared between week 6 and 12 responders, and in patients with improvements in pain ≥MCID at week 12 (week 12 responders/non-responders). (bmj.com)
  • Week 12 pain responders had better clinical outcomes at week 24 than non-responders. (bmj.com)
  • Methods Clinical and radiographic 5-year outcome was compared between initial strategies. (bmj.com)
  • At 5 years there was no longer any significant difference for clinical and radiographic outcomes between treatment strategies applied during the first 2 years. (bmj.com)
  • Good-response to treatment independently predicts significantly better 5-year clinical and radiographic outcome. (bmj.com)
  • 9 Disease activity during the first 3 months of treatment has been related to clinical and radiographic outcome after the first year of treatment, 6 10 11 and an early treatment response can predict the long-term work disability outcome. (bmj.com)
  • Outcome after surgical treatment of dermatofibrosarcoma protuberans: Is clinical follow‐up always indicated? (wiley.com)
  • The most powerful use of BHOM has been documented in healthcare's first randomized clinical trial of a referral process using outcome data. (wikipedia.org)
  • Purpose: To compare the clinical outcomes of MSC injection and arthroscopic marrow stimulation treatment with those of arthroscopic marrow stimulation treatment alone for the treatment of OLTs in older patients. (researchgate.net)
  • Patients were divided into 2 groups: 35 patients (37 ankles) treated with arthroscopic marrow stimulation treatment alone (group A) and 30 patients (31 ankles) who underwent MSC injection along with arthroscopic marrow stimulation treatment (group B). Clinical outcomes were evaluated according to the visual analog scale (VAS) for pain, the American Orthopaedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Scale, and the Roles and Maudsley score. (researchgate.net)
  • Large lesion size (≥109 mm(2)) and the existence of subchondral cysts were significant predictors of unsatisfactory clinical outcomes in group A (P = .04 and .03, respectively). (researchgate.net)
  • A trial of a treatment that had a similar clinical effect would have a large increase in power, allowing for a reduction in the required sample size. (nih.gov)
  • We investigated whether the use of ACEI/ARBs affects the clinical outcomes of primary breast cancer patients receiving taxane and anthracycline-based neoadjuvant chemotherapy. (jcancer.org)
  • The lateral cephalometric radiograph is a standard component of clinical records taken for orthodontic diagnosis and treatment planning. (thejcdp.com)
  • Univariate analysis indicated that age, histology, T stage, and clinical stage were independent prognosticators of OS and CSS, while treatment option was only associated with OS. (jcancer.org)
  • She has also developed methods for studying dynamic treatment regimes to improve recurrent disease management using clinical trial data and observational databases. (mskcc.org)
  • Despite progresses made in recent years, there is still a lack of effective treatments for acute ischemic stroke (AIS) in clinical practices. (biomedcentral.com)
  • We, therefore, performed a 1-year, nationwide, evaluation on the clinical outcomes (i.e., mortality rates and complication rates) and treatment costs for hospitalized CKD patients across the 3 main health insurance schemes. (biomedcentral.com)
  • The outcomes focused on were clinical outcomes, access to special care and equipment (especially dialysis), and expenses on CKD patients. (biomedcentral.com)
  • Our particular focus was on differences in (i) clinical outcomes, (ii) access to special care and equipment (notably dialysis), and (iii) budgeting. (biomedcentral.com)
  • Aim: The present study evaluated the efficacy and safety of ramucirumab (RAM) in clinical practice as post-treatment, following atezolizumab plus bevacizumab (Atz/Bev) for advanced hepatocellular carcinoma (HCC) with alpha-fetoprotein (AFP) levels of ≥400 ng/ml. (iiarjournals.org)
  • Following the positive results of the IMbrave150 study ( 1 ), atezolizumab plus bevacizumab (Atz/Bev) combination therapy is widely used as 1st-line treatment in clinical practice for patients with advanced hepatocellular carcinoma (HCC) ( 2 ). (iiarjournals.org)
  • According to the Clinical Practice Guidelines for the Treatment of Hepatocellular Carcinoma ( 4 ), all these five agents are equally recommended as 2nd-line therapy for patients with advanced HCC after disease progression (PD) with Atz/Bev. (iiarjournals.org)
  • The clinical characteristics and outcomes of 2019 novel coronavirus (COVID-19) pneumonia are different in Hubei and out of Hubei in China. (researchsquare.com)
  • We investigated 169 patients of COVID-19 pneumonia in two centers in Hunan Province, and divided into two groups according to epidemiology history, aiming to analyze the difference of clinical characteristics and outcomes in the two groups. (researchsquare.com)
  • We made a comprehensive comparison and analysis of their clinical features and outcomes in order to explore the differences between the two groups. (researchsquare.com)
  • Notably, although pre-treatment with convalescent plasma prevented most signs of clinical disease, it did not prevent anosmia. (nature.com)
  • Background/aims To investigate the yearly change of real-world outcomes for best corrected visual acuity (BCVA) after 2-year clinical intervention for treatment-naïve diabetic macular oedema (DMO). (bmj.com)
  • clinical outcome was measured by 90-day mRS. (ajnr.org)
  • These include Outcome Studies, Clinical Reports, Mechanisms Papers, Review Articles and Meta-Analyses, and Skeptical and Opposing Viewpoints. (eftuniverse.com)
  • A literature search identified 51 peer-reviewed papers that report or investigate clinical outcomes following the tapping of acupuncture points to address psychological issues. (eftuniverse.com)
  • Several studies have provided data regarding clinical outcomes for CRE infections. (cdc.gov)
  • There are few published clinical data available on the effectiveness of colistin, tigecycline, fosfomycin, and gentamicin (which are likely to be active in vitro against CRE) for the treatment of CSE infections. (cdc.gov)
  • CCM comprises 6 components that are hypothesized to affect functional and clinical outcomes associated with disease management. (cdc.gov)
  • However, not all patients experience improvement, and although predictors of treatment outcome have been identified, few are consistent over time and across studies. (frontiersin.org)
  • The results suggest that measuring treatment self-efficacy may be a valuable tool to identify patients at risk of dropping out, and that treatment self-efficacy could be a predictor and moderator of symptom reduction in guided Internet-delivered therapy. (frontiersin.org)
  • This calls for ways in which more patients can receive treatment for their disorder. (frontiersin.org)
  • Patients who develop severe stroke symptoms due to acute internal carotid artery occlusion eventually in combination with a thromboembolic obstruction of the middle cerebral artery incur a major risk of developing extensive MCA infarction with a poor outcome. (ajnr.org)
  • The purpose of this study was to evaluate the outcome for patients with tandem occlusions in the MCA and/or distal ICA, retrospectively, who had undergone stent implantation in the proximal segment of the ICA in addition to intra-arterial thrombolysis. (ajnr.org)
  • 1 However, there is a subgroup of patients who develop severe stroke symptoms due to acute internal carotid artery occlusion eventually in combination with a thromboembolic obstruction of the central arteries, such as the terminal carotid segment or the middle cerebral artery, and subsequently incur a major risk of developing extensive MCA infarction with a poor outcome. (ajnr.org)
  • The NNT determines the number of patients that need to be treated in order to obtain the benefit of interest in one additional patient (small NNTs indicate a favourable treatment effect). (bmj.com)
  • This article describes experiences in the community of Göteborg over 20 years with regard to treatment, outcome, and predictors of outcome among patients hospitalised alive after out of hospital cardiac arrest. (bmj.com)
  • RR/MDR TB cases are difficult to treat, and patients need prolonged treatment courses, which are burdened by frequent drug-related adverse events. (cdc.gov)
  • With the $200 billion behavioral health marketplace in a state of public health crisis as defined by the US Surgeon General with most patients receiving substandard care, outcome management is helping to provide quality controls, data and structure for a large subsection (more than 27%) of the US population. (wikipedia.org)
  • Especially with session-by-session assessments, real-time scoring and report generation the data provides clinicians and patients with excellent feedback about the course of treatment and whether adjustments need to be made to the treatment plan. (wikipedia.org)
  • Background: The ideal treatment for osteochondral lesions of the talus (OLTs) is still controversial, especially in older patients. (researchgate.net)
  • These correlations were not observed in group B. Conclusion: Injection of MSCs with marrow stimulation treatment was encouraging in patients older than 50 years compared with patients treated with marrow stimulation treatment alone, especially when the lesion size was larger than 109 mm(2) or a subchondral cyst existed. (researchgate.net)
  • Although still in the early stages of application, MSCs may have great potential in the treatment of OLTs in patients older than 50 years, and more evaluations of its effect should be performed. (researchgate.net)
  • No differences in pCR and survival outcomes were seen between ACEI/ARB users and non-users among breast cancer patients receiving neoadjuvant chemotherapy. (jcancer.org)
  • In general, PIPs for ALL are more intensive and regimented as compared with regimens used for adults, and the characteristics of the protocols are often credited with the superior outcomes observed in pediatric patients with ALL. (medpagetoday.com)
  • Analysis of secondary outcomes showed that patients in the hyperCVAD group had a significantly higher rate of leukemic relapse (38.6% vs 5.6%, P =0.005). (medpagetoday.com)
  • A fourth of all patients underwent stem-cell transplantation, and the rate did not differ significantly by treatment. (medpagetoday.com)
  • At last follow-up, 89.1% of patients treated with PIPs remained in CR as compared with 71.9% for hyperCVAD treatment ( P =0.004). (medpagetoday.com)
  • Monotherapy remains an option for PAH treatment 14 , 15 , 16 recommended in guidelines 17 as first-line therapy for World Health Organization functional class (FC) II-III patients, with the same grade of evidence and recommendation (IA-IB) for endothelin receptor antagonists (ERA) and phosphodiesterase-5 (PDE5) inhibitors. (jrheum.org)
  • Piao Y, Jiang C, Yan F, Ye Z, Fu Z, Jiang H, Jiang Y, Wang Y, Wang F. Therapeutic patterns and outcomes in older patients (aged ≥65 years) with stage II-IVB Nasopharyngeal Carcinoma: an investigational study from SEER database. (jcancer.org)
  • Currently, the optimal treatment regimens for older nasopharyngeal carcinoma (NPC) patients remained unclear. (jcancer.org)
  • The aim of this retrospective study is to investigate therapeutic patterns and survival outcomes for a cohort of older NPC patients receiving radiation therapy (RT) with or without chemotherapy (CT). (jcancer.org)
  • Among these NPC patients with aged ≥65 years reported in the SEER database, treatment with RT plus CT provided longer OS than those treated with radiation therapy alone. (jcancer.org)
  • The Auckland Advanced Breast Cancer Review (AABC) was a review of patients diagnosed with advanced inoperable/metastatic breast cancer (ABC) within the Auckland region of New Zealand, commissioned in response to a Breast Cancer Registry report (BCFNZR) that showed poor and inequitable survival outcomes. (hindawi.com)
  • While treatment uptake and survival outcomes were generally comparable across ethnicity and district health boards, dnMBC survival outcomes were considerably poorer than expected, earmarking this subset of patients with ABC for more in-depth research. (hindawi.com)
  • This inequity was reflected in the BCFNZR, where Maori had the poorest survival outcomes amongst patients with ABC compared to all other ethnicities in NZ, with a medOS of only 12.8 months. (hindawi.com)
  • The secondary objectives include: 1) to compare the effectiveness of common treatment regimens, 2) to analyze the cost-effectiveness of different treatment regimens for AIS, 3) to analyze the incidence of adverse events and complications in enrolled patients with AIS, 4) to analyze the effect of Trial of Org 10,172 in Acute Stroke Treatment (TOAST) classification on the specific therapies during acute phase treatment period. (biomedcentral.com)
  • The CASTOR study will help to find favorable cost-utility treatment regimens for AIS and improve the overall treatment outcome of Chinese patients with AIS. (biomedcentral.com)
  • Aim: To evaluate the relationship between health literacy and health and treatment outcomes (concordance with oral anticoagulants, Normalized Ratio control and occurrence of complications) in patients with cardiovascular pathology. (biomedcentral.com)
  • Further, it is vital that patients demonstrate adequate self-care, along with treatment concordance and sufficient knowledge to avoid or mitigate adverse effects, to maintain the effectiveness of this treatment. (biomedcentral.com)
  • The authors of this manuscript investigated spliced leader (SL)-RNA detection in blood and cerebrospinal fluid to assess treatment outcomes in 97 patients with gambiense -HAT in collaboration with a phase II/III trial of acoziborole. (dndi.org)
  • International non-profit developing safe, effective, and affordable treatments for the most neglected patients. (dndi.org)
  • Patients and Methods: Of the 77 patients treated with Atz/Bev at our institution, 13 patients for whom RAM was introduced as post-treatment following Atz/Bev were enrolled in this retrospective study. (iiarjournals.org)
  • Conclusion: In HCC patients with AFP levels of ≥400 ng/mL, RAM after Atz/Bev is expected to be an effective treatment option. (iiarjournals.org)
  • Additional studies are needed to confirm the efficacy and safety of RAM as 2nd-line treatment after Atz/Bev in Child-Pugh A patients. (iiarjournals.org)
  • In summary, we found that imported patients more likely developed into severe patients than local patients and required more powerful treatments. (researchsquare.com)
  • If patients get proper treatment, they can feel improvement within two to four weeks," coauthor Jing-Wen Yang, MD, PhD, also of Beijing University of Chinese Medicine, told MedPage Today . (medpagetoday.com)
  • Patients, outcome assessors, and statistical analysts were blinded to arm assignment but acupuncturists were not. (medpagetoday.com)
  • Low GCS score did not correlate with poor neurologic outcome in patients with acute basilar artery thrombosis managed with IA therapy. (ajnr.org)
  • To identify and understand how socioeconomic factors affect a Hispanic patients health outcome and treatment of malignant melanoma with comparisons to white, non-Hispanic (WNH) patients. (unl.edu)
  • This early study suggests that adjunctive treatment with a standardized extract of Withania somnifera provides significant benefits, with minimal side effects, for negative, general, and total symptoms and stress in patients with recent exacerbation of schizophrenia. (psychiatrist.com)
  • 90 patients continued treatment with an antidepressant for 52 weeks and 87 were switched to placebo at 8 weeks. (medscape.com)
  • At 52 weeks, 28 patients (31%) in the 52-week group had experienced any mood episode (primary outcome) compared with 40 patients (46%) in the 8-week group. (medscape.com)
  • However, in a sensitivity analysis of the primary outcome after week 6, when treatment between the two groups differed, patients continuing antidepressant treatment were 40% less likely to experience a relapse of any mood event (HR, 0.60) and 59% less likely to experience a depressive episode (HR, 0.41) relative to the placebo group. (medscape.com)
  • From the point where the two groups began receiving different treatments, we see a significant benefit for patients who continued treatment with antidepressants," Yatham said in a news release. (medscape.com)
  • 718 patients, along with the considerable heterogeneity among the included studies, but not among the type of infection, may justify the absence of statistical significance. (cdc.gov)
  • A key relevant factor could be the higher frequency of inappropriate empirical treatments among the CRE patients. (cdc.gov)
  • Only 2 of the included studies provided comparative data for patients who received appropriate empirical antibiotic treatment. (cdc.gov)
  • Those studies showed that patients with infections caused by CRE were significantly more likely than those infected by CSE to receive inappropriate antibiotic treatment. (cdc.gov)
  • The TB treatment outcome data of al made to expand partnerships and bring TB case finding and treatment outcome districts was entered into SPSS , version all stakeholders on board in order to reports were reviewed and all patients 17. (who.int)
  • For all forms of TB, 19% of patients were lost to follow-up from treatment. (who.int)
  • Back-specific functioning, general health, work disability specific to low back pain, safety outcomes, and treatment adherence did not differ between patients receiving OMT and sham OMT. (medscape.com)
  • Conclusion: Osteomyelitis is a common complication of Noma and its treatment is of paramount importance for adequate management of Noma patients. (bvsalud.org)
  • The prognostic value of early response to treatment in addition to established predictors was analysed by multiple linear regression analyses. (bmj.com)
  • 1 , - , 4 Next to known predictors of long-term outcome of RA, which are assessed at baseline, 5 , - , 8 early response to treatment also could be predictive. (bmj.com)
  • We propose just a way for horizontal strabismus surgical treatment optimisation, a step forward to a person-centred medicine and with this study we would like to encourage the researchers to improve these models by finding more predictors and validation in a larger research. (bmj.com)
  • The purpose of this Funding Opportunity Announcement (FOA) is to invite institutions to participate as the Leadership and Data Coordinating Center (LDCC) for the Sleep Predictors of Opioid Use Disorder (OUD) Treatment and Outcomes Program. (nih.gov)
  • The overall goals of this program are a) to uncover novel mechanisms underlying the bidirectional interrelationship between sleep/circadian rhythm and OUD, and b) to delineate sleep and/or circadian-based predictors of OUD treatment response and outcomes. (nih.gov)
  • Treatment regimen (p = 0.017) and functional class (p = 0.007) were found to be independent predictors of mortality. (jrheum.org)
  • Objective To assess the impact of certolizumab pegol (CZP) on patient-reported outcomes (PROs) in rheumatoid arthritis (RA), and to interpret these results using number needed to treat (NNT), and associations between PRO responses and longer term outcomes. (bmj.com)
  • Objective To investigate the long-term effects of the tight control (TC) and conventional (CT) methotrexate-based strategies of the Computer Assisted Management in Early Rheumatoid Arthritis trial in early rheumatoid arthritis and evaluate the predictive value of an early response to treatment. (bmj.com)
  • The primary objective of the present study is to analyze the current treatment status of AIS in real world settings. (biomedcentral.com)
  • The primary objective/endpoint of the study is to compare the two treatments in terms of progression-free survival, or the length of time that each participant is alive without the cancer significantly worsening according to defined assessment criteria. (biomedcentral.com)
  • The objective of this study was to determine whether smokers recruited during the New Year period differ on measures of motivation and desire to quit, recruitment and retention rates, website utilization rates, and short-term cessation outcomes compared to smokers recruited at other times. (jmir.org)
  • We are planning to research on the long-term effect of acupuncture that incorporates objective outcomes and daily measurement of symptoms. (medpagetoday.com)
  • Objective We performed a randomised trial in very preterm, small for gestational age (SGA) babies to determine if prophylaxis with granulocyte macrophage colony stimulating factor (GM-CSF) improves outcomes (the PROGRAMS trial). (bmj.com)
  • The objective of this study was to determine how CCM has been applied in US primary care settings to provide care for people who have diabetes and also to describe outcomes of CCM implementation. (cdc.gov)
  • HOUSTON -- Pediatric treatment protocols outperformed standard therapy for adolescents and young adults (AYAs) with Philadelphia chromosome-negative acute lymphocytic leukemia (ALL), a retrospective cohort study showed. (medpagetoday.com)
  • The cohort had a median follow-up of 24 months, and the primary outcomes were OS, EFS, and RFS. (medpagetoday.com)
  • Overall, the cohort had a 2-year EFS of 65.8%, and 2-year RFS of 75.6% but both outcomes were significantly improved with PIPs ( P =0.004, P =0.0001, respectively). (medpagetoday.com)
  • 3 hours, 33.3% had good neurologic outcome-a similar rate to that of the overall cohort. (ajnr.org)
  • A retrospective, cohort study was conducted in which TB treatment outcome reports were reviewed. (who.int)
  • A statistical significance was determined at p = 0.05. (thejcdp.com)
  • As noted, this difference did not achieve statistical significance ( P =0.158). (medpagetoday.com)
  • Statistical significance was demonstrated between time to IA therapy within 6 hours and mRS ≤ 2. (ajnr.org)
  • Because of selective reporting bias and the heterogeneity of study outcomes, it is not possible to combine similar studies in a meta-analysis. (hindawi.com)
  • Heterogeneity across studies was assessed using the I² statistic with sub-group analysis. (who.int)
  • She has developed methods to integrate evidence from various data domains and sources, effectively addressing patient heterogeneity and studying personalized treatment strategies to enhance treatment responses and patient outcomes. (mskcc.org)
  • For subgroups of trials with similar types of intervention and without substantial statistical heterogeneity, we estimated pooled effects using a Mantel-Haenszel fixed-effect method. (who.int)
  • Secondary outcomes evaluated stress and inflammatory indices using the Perceived Stress Scale (PSS), S100 calcium-binding protein B (S100B), and C-reactive protein (CRP). (psychiatrist.com)
  • However, a prespecified sensitivity analysis of the primary outcome and of the secondary analyses suggests that continuing antidepressant therapy for 52 weeks may prolong the time to a depressive relapse. (medscape.com)
  • Because the primary outcome is negative and the prespecified sensitivity analysis is positive and the secondary outcomes are positive, some clinicians will pick the position that they work and some that they don't work," lead investigator Lakshmi Yatham, MBBS, with University of British Columbia (UBC) in Vancouver, Canada, told Medscape Medical News . (medscape.com)
  • Five secondary outcomes, safety, and treatment adherence were also assessed. (medscape.com)
  • Identifying urban-rural differences in HIV care outcomes is crucial for addressing HIV-related dis- parities among Black persons with HIV infection. (cdc.gov)
  • The outcome differences between children and AYAs have led to evaluations of PIPs in the age group. (medpagetoday.com)
  • Results We found no significant differences in cognitive, general health or educational outcomes between 83 of 106 (78%) surviving children in the GM-CSF arm compared with 81 of 110 (74%) in the control arm. (bmj.com)
  • No significant between-treatment differences were noted in body weight, vital signs, or laboratory measures, which remained stable. (psychiatrist.com)
  • Pain acceptance was measured with the Chronic Pain Acceptance Questionnaire (CPAQ), pain outcomes included pain intensity (Numeric Rating Scale, NRS) as well as affective and sensory pain perception (Pain Perception Scale, SES-A and SES-S). Regression analyses controlling for the pre-treatment values of the pain outcomes, age, and gender were performed. (mdpi.com)
  • In addition to evaluating the impact of treatment on individual patient-reported outcome (PRO) measures, MCIDs can be used in number needed-to-treat (NNT) or predictive analyses to better understand the magnitude of treatment benefit. (bmj.com)
  • Students are introduced to a range of advanced statistical topics to address issues that arise in cost effectiveness analyses, including the analysis of cost data, time-to-event data, and treatment effect estimation using data from observational studies. (sheffield.ac.uk)
  • Provide insight into how the results of statistical analyses are used to inform economic models. (sheffield.ac.uk)
  • Conduct analyses for data on costs, time to event, and observational data using specialist statistical software. (sheffield.ac.uk)
  • Real-world data on treatment regimens, outcomes and costs are collected at baseline (Visit 1) and during subsequent visits (Visit 2 to Visit 5) after medication treatments. (biomedcentral.com)
  • Primary outcomes were change from baseline to end of treatment on the Positive and Negative Syndrome Scale (PANSS total, positive, negative, and general symptoms) between treatment groups. (psychiatrist.com)
  • The process was repeated until statistical nondifference of baseline school characteristics between the groups was ensured. (who.int)
  • Surveyors were masked about the treatment status in both baseline and endline surveys. (who.int)
  • Demographic, diagnostic, treatment, and survival data were extracted from electronic records for statistical analysis. (hindawi.com)
  • Despite improvements in treatment options and survival outcomes in recent years, NZ ABC mortality rates continue to exceed the OECD average [ 1 ]. (hindawi.com)
  • Despite observable gains in survival outcomes over the 15-year period, the BCFNZR findings were disappointing. (hindawi.com)
  • Standard methods for survival analysis, such as the time-dependent Cox model, may produce biased effect estimates when there exist time-dependent confounders that are themselves affected by previous treatment or exposure. (nih.gov)
  • In this study, CD4 lymphocyte count is both a time-dependent confounder of the causal effect of zidovudine on survival and is affected by past zidovudine treatment. (nih.gov)
  • Therefore, we believe that effective self-care, adherence to treatment with oral anticoagulants and prevention of complications could be directly related to the level of health literacy. (biomedcentral.com)
  • The current study explored whether changes in pain acceptance in the very early treatment phase of an interdisciplinary cognitive-behavioral therapy (CBT)-based treatment program for chronic pain predict pain outcomes. (mdpi.com)
  • and chronic treatment with diuretics before hospital admission (OR 0.59, 95% CI 0.43 to 0.81). (bmj.com)
  • Major indicators for a lower chance were high age, requirement for atropine in the emergency department, and chronic treatment with diuretics before cardiac arrest. (bmj.com)
  • The concept of an "illness career" which has been successfully applied to other chronic diseases such as mental illness, enables identification of a wide-range of health-seeking behaviors, and outcomes in the context of evolving treatment guidelines [ 10 - 12 ]. (biomedcentral.com)
  • 5 For these reasons, improving health outcomes of people with chronic physical disease, particularly those with psychological illness as well, is a major challenge for improving the health of ageing populations worldwide. (bmj.com)
  • Treatment of chronic pulmonary heart disease (CPHD), a common disease, has over recent years been studied using traditional Chinese medicine (TCM) due to many high-profile benefits. (hindawi.com)
  • To solve these problems, the development of a core outcome set for traditional Chinese medicines for the treatment of chronic pulmonary heart disease (COS-TCM-CPHD) is required. (hindawi.com)
  • Purpose We studied the efficacy of osteopathic manual treatment (OMT) and ultrasound therapy (UST) for chronic low back pain. (medscape.com)
  • [ 14 ] The OSTEOPAThic Health outcomes In Chronic low back pain (OSTEOPATHIC) Trial aims to fill these voids by studying OMT and UST for shortterm relief of nonspecific chronic low back pain. (medscape.com)
  • TB incidence decreased in Egypt over the last two decades, but treatment outcomes were unsatisfactory, with variations across the different regions. (who.int)
  • HIV treatment career (dynamic developmental trajectories that people living with HIV experience throughout a lifetime) for individuals living with HIV is crucial to improve health outcomes and mitigate ongoing HIV transmission. (biomedcentral.com)
  • We conducted a retrospective descriptive analysis of TB cases and treatment outcomes using routine surveillance data from the national TB database for the period 2008-2016. (who.int)
  • In 2018, the World Health Organization (WHO) published new treatment guidelines, relying on a large-scale meta-analysis ( 5 ), which revolutionized the traditional hierarchy of anti-TB drugs ( 6 ). (cdc.gov)
  • Behavioral health outcome management (BHOM) involves the use of behavioral health outcome measurement data to help guide and inform the treatment of each individual patient. (wikipedia.org)
  • In behavioral healthcare (mental health and substance abuse treatment) routine health outcomes measurement has expanded beyond aggregating measurements for quality improvement studies and has placed equal emphasis on the therapeutic gain delivered by real-time patient-level outcome feedback. (wikipedia.org)
  • Some health plans now require the integration of BHOM into routine care and treatment planning and a well designed BHOM system provides the clinician feedback and guidance to keep up with these evidence-based principals. (wikipedia.org)
  • Main outcome measures Social role disability (Sheehan disability scale), global quality of life rating, and World Health Organization disability assessment schedule (WHODAS-2) scales to measure disabilities in activities of daily living (mobility, self care, household maintenance). (bmj.com)
  • At the time of reporting to Texas poison centers, the patient was already at or en route to a health care facility in 71.9% of the cases and referred to a healthcare facility in 20.5% of the cases. (cdc.gov)
  • Unfortunately, inequitable health outcomes remain pervasive [ 6 ]. (hindawi.com)
  • Maori health outcomes have historically lagged behind non-Maori across a range of cancer and noncancer related indicators [ 7 ]. (hindawi.com)
  • Variables referring to anticoagulant treatment with vitamin K antagonists (years of treatment, adequate control, polypharmacy and occurrence of complications, among others) and health literacy (Health Literacy Questionnaire) were analysed. (biomedcentral.com)
  • Health literacy has a relevant influence on the adequate self-management of anticoagulation treatment and the frequency of complications. (biomedcentral.com)
  • With these requirements in place, health literacy (HL) could be an essential factor for the self-management of anticoagulation treatment, in line with other cardiovascular diseases [ 7 ]. (biomedcentral.com)
  • Some preliminary studies exploring the effect of HL on awareness about AF and medication concordance have demonstrated that people with inadequate or insufficient levels of HL have poorer health outcomes, have less knowledge about their health problems and diseases, use preventive services less, and suffer from higher mortality [ 9 , 10 ]. (biomedcentral.com)
  • So far, HL has been linked to the health conditions and outcomes of people with cardiovascular disease. (biomedcentral.com)
  • Outcomes were assessed at 5 years to determine neurodevelopmental and general health status and educational attainment. (bmj.com)
  • Conclusions The administration of GM-CSF to very preterm SGA babies is not associated with improved or more adverse neurodevelopmental, general health or educational outcomes at 5 years. (bmj.com)
  • The Further Statistical Methods for Health Economic Analysis module is led by Jean Hamilton & Sarah Ren. (sheffield.ac.uk)
  • The module builds on key concepts introduced in the Medical Statistics and Evidence Synthesis (HAR6170) and Economic Evaluation (HAR6260) modules in order to develop further the statistical skills needed in health economics. (sheffield.ac.uk)
  • Provide students with an overview of advanced statistical methods that are necessary in health economics. (sheffield.ac.uk)
  • 1 Skin health is inextricably linked to both physical health outcomes like infection and hydration and to psychological outcomes like anxiety and depression. (naturalmedicinejournal.com)
  • Although cataracts are not preventable, their surgical treatment is one of the most cost-effective interventions in health care. (who.int)
  • To minimize or prevent a surge in the prevalence of blindness from these two causes, appropriate methods of screening and medical treatment need to be further assessed and incorporated as priorities into national health-care strategies. (who.int)
  • In this study, we examine prevalence, awareness, treatment, and control of high LDL cholesterol in New York City adults by using the first community Health and Nutrition Examination Survey (NYC HANES). (cdc.gov)
  • Permission was sought from programme (NTP) adopted the World with the outcome of TB cases registered the NTP in the Ministry of Health, Health Organization (WHO) DOTS in Pakistan. (who.int)
  • Title : Health disparities are important determinants of outcome for children with solid tumor malignancies Personal Author(s) : Austin, Mary T.;Nguyen, Hoang;Eberth, Jan M.;Chang, Yuchia;Heczey, Andras;Hughes, Dennis P.;Lally, Kevin P.;Elting, Linda S. (cdc.gov)
  • We summarized details on CCM application and health outcomes for 16 studies. (cdc.gov)
  • The results showed that high treatment self-efficacy was a predictor of both lower dropout rates and greater symptom reduction. (frontiersin.org)
  • Statistical tests are used to judge whether the results of a study could be due to chance and would not be confirmed if the study was repeated. (aidsmap.com)
  • However, since the IMbrave150 trial did not provide detailed results on post-treatment after Atz/Bev failure, the established regimen for post-treatment after Atz/Bev is unknown. (iiarjournals.org)
  • Here, we present the results of a large-scale, interdisciplinary ecosystem restoration experiment, in which the restoration outcomes across 52 tree islands established in a landscape dominated by an industrial oil palm plantation (140 ha) were observed and quantified three to five years after establishment. (nature.com)
  • These have revealed that IA thrombolysis results in significantly higher recanalization rates, 6 , 7 , 10 and that recanalization is independently associated with reduced mortality and better functional outcome. (ajnr.org)
  • The 18 randomized controlled trials in this sample were critically evaluated for design quality, leading to the conclusion that they consistently demonstrated strong effect sizes and other positive statistical results that far exceed chance after relatively few treatment sessions. (eftuniverse.com)
  • interpret results from numerical calculations, and analyse sources of error · describe and present Statistical Mechanical theories for liquids and solutions, and · also evaluate approximations and assess limitations. (lu.se)
  • Pooled results from two trials of bupropion did not detect a benefit of treatment at six months or longer (RR 0.89, 95% CI 0.54 to 1.44, 293 participants) but the confidence interval was wide. (who.int)
  • A low population-screening rate, a high proportion of pulmonary TB cases without sputum test results and a low treatment success rate suggest areas for improvement in the National TB Program. (who.int)
  • TB laboratory results, case notifications, HIV testing results and treatment outcomes were analysed by disease category, geographic areas and demographic variables. (who.int)
  • Results There was no statistical interaction between OMT and UST. (medscape.com)
  • Dr. Chen's main research interest lies in developing statistical and machine learning methods to facilitate precision medicine, which tailors treatments based on individual patient characteristics. (mskcc.org)
  • Explain how different treatment switching adjustment methods work, and why and when it is necessary to adjust for treatment switching. (sheffield.ac.uk)
  • apply numerical methods, such as Molecular Dynamics Metropolis Monte Carlo simulations · use Statistical Mechanical tools with, as well as without, the aid of computer programs to calculate various properties of macroscopic systems. (lu.se)
  • These can be evaluated by the measurement and analysis of related outcomes. (hindawi.com)
  • Another large retrospective study carried out in Kenya found no difference in the risk of premature birth or other adverse birth outcomes between women who started isoniazid preventive therapy (IPT) during pregnancy and those who didn't. (aidsmap.com)
  • The two studies provide reassuring evidence that isoniazid preventive treatment does not result in a higher rate of adverse birth outcomes in pregnant women. (aidsmap.com)
  • Some studies have raised concerns that IPT may be associated with adverse birth outcomes for women with HIV. (aidsmap.com)
  • The IMPAACT P1078 TB APPRISE randomised study found that women who started IPT during pregnancy experienced a higher rate of adverse birth outcomes (including stillbirth, spontaneous abortion, low birth weight in an infant, preterm delivery, or congenital anomalies in an infant). (aidsmap.com)
  • Gathering further data on adverse birth outcomes in pregnant women with HIV exposed to IPT is therefore a priority for informing decisions about the use of IPT in pregnancy. (aidsmap.com)
  • Participants will be monitored for response to treatment (using radiological imaging), adverse events and quality of life during both randomised treatment and subsequent follow-up. (biomedcentral.com)
  • If the addition of TAK228 to weekly paclitaxel chemotherapy is shown to significantly improve this statistically, and adverse events and quality of life are not significantly worse than standard treatment, then TAK228 plus weekly paclitaxel could potentially be taken forward within the context of a larger phase III trial. (biomedcentral.com)
  • The current study aimed to examine whether treatment self-efficacy (self-efficacy regarding the mastery of obstacles during treatment) in guided Internet-delivered therapy for anxiety disorders in adults could be a predictor of lower dropout rates and greater symptom reduction. (frontiersin.org)
  • The present study investigates 5-year data of a 2-year methotrexate (MTX) based tight control treatment (TC) strategy compared to conventional MTX-based treatment (CT) strategy, and the (added) predictive value of an early response (at 6 months) to treatment for 5-year outcome with respect to disease activity and radiographic progression. (bmj.com)
  • The present study was conducted to assess the utility of cephalometric radiography and analysis in modern orthodontic diagnosis and treatment planning. (thejcdp.com)
  • In face of changing treatment patterns and increasing demand from medical insurers for cost-effectiveness data in China, a large-scale registry study examining the real-world patterns of AIS in hospitals is needed. (biomedcentral.com)
  • As subtle benefits in outcome may not be ascertainable until school age we performed an outcome study at 5 years. (bmj.com)
  • The researchers note that the decision by the study team to include relapses that occurred during the first 6 weeks of the study may have affected the primary outcome. (medscape.com)
  • The purpose of this study was to examine the outcomes of various types of TB cases registered in Pakistan over a 2-year period and compare those outcomes among the different provinces and regions of the country. (who.int)
  • The South African Medical Research Council carried out a prospective analysis of pregnant women with HIV enrolled in three provinces during 2019, to assess the impact of IPT exposure on birth outcomes. (aidsmap.com)
  • Median number of lines of systemic treatment was two, with similar treatment exposure between ethnic groups. (hindawi.com)
  • Moreover, mortality's effect was compared between different treatment regimens. (jrheum.org)
  • Describe how observational data can be used to explain causal inference and be able to select and apply the appropriate methodology to estimate treatment effects. (sheffield.ac.uk)
  • apply and utilize various Statistical Mechanical ensembles, and describe relations between these ensembles · account for the connection between Statistical Mechanics and Thermodynamics. (lu.se)
  • CCM in US primary care settings to provide care for people who have diabetes and to describe outcomes of CCM implementation. (cdc.gov)
  • Treatment self-efficacy was measured at pre-treatment. (frontiersin.org)
  • Significant interaction effects between time and treatment self-efficacy were found for several of the nine modules that constitutes the treatment program, suggesting that treatment self-efficacy could be a moderator of symptom reduction. (frontiersin.org)
  • Yatham and colleagues assessed the safety and efficacy of continuing adjunctive antidepressant treatment (escitalopram or bupropion XL) for 52 weeks after remission, compared with discontinuing antidepressant therapy at 8 weeks after remission. (medscape.com)
  • Evidence-based management of bruxism is hampered by the limited number of randomized controlled studies available for assessing the efficacy of various treatment strategies, the historical lack of understanding with respect to the etiology of the condition, and the changing diagnostic criteria by which bruxism is defined. (medscape.com)
  • The course aims to provide a basic understanding of Statistical Mechanics. (lu.se)
  • We retrospectively determined the effects of pre-XDR/XDR TB resistance on outcomes and safety of MDR TB treatment in France. (cdc.gov)
  • Investigators retrospectively compared outcomes in AYAs treated with a PIP or hyperCVAD (cyclophosphamide, vincristine sulfate, doxorubicin hydrochloride [Adriamycin], methotrexate, cytarabine, and dexamethasone) at King Hussein Cancer Center from 2010 to 2022. (medpagetoday.com)
  • Initial stroke severity, degree of successful revascularization, and the side of ischemia were found to independently predict the functional outcome at 3 months after treatment. (ajnr.org)
  • The evaluator was blinded as to treatment and functional outcome. (lww.com)
  • Multiple regression analysis showed that early response to treatment is an independent predictor of 5-year outcome, irrespective of treatment strategy. (bmj.com)
  • The relative importance of cephalometric analysis in orthodontic diagnosis and treatment planning has varied throughout the years. (thejcdp.com)
  • Critically evaluate statistical analysis carried out for inclusion in economic evaluation models. (sheffield.ac.uk)
  • Apart from the sample size, other variables that have not been analyzed might have affected the strength of the death, or outcomes, analysis. (cdc.gov)
  • However, it is still difficult to predict strabismus surgery outcome with certainty. (bmj.com)
  • Conclusions The difference in disease activity between treatment strategies disappeared over the years. (bmj.com)
  • Describing the nuances of this outcome measure is particularly important because using it, while ignoring mortality, could result in misleading conclusions. (nih.gov)
  • I]n the absence of a regulatory guideline on the magnitude of active drug response rate over placebo that can be considered clinically relevant, an expert group suggested that 10% to 15% improvement over placebo would constitute a clinically meaningful outcome," Liu and colleagues wrote. (medpagetoday.com)
  • For a treatment to be designated as "efficacious," the studies must demonstrate that the treatment is better than a wait list, placebo, or established efficacious treatment. (eftuniverse.com)
  • Treatment impact on PROs, NNT to achieve simultaneous improvements in multiple PROs and correlations between PROs were calculated. (bmj.com)
  • Despite improvements in treatments for human African trypanosomiasis (HAT), there is a risk of relapse. (dndi.org)
  • Cataract, responsible for 50% of blindness globally, remains the leading cause of visual impairment in all regions of the world, despite improvements in surgical outcomes. (who.int)
  • High prevalence of high LDL cholesterol and inadequate treatment and control contribute to preventable illness and death, especially among those at highest risk. (cdc.gov)
  • The Chinese Acute Ischemic Stroke Treatment Outcome Registry (CASTOR) is designed to evaluate the patterns and cost-effectiveness of current treatments for AIS in real-world settings in China. (biomedcentral.com)
  • Conclusion : L'ostéomyélite chronique de membres en milieu tropical atteint les adolescents. (bvsalud.org)
  • Outcome studies are further divided by condition, such as anxiety, depression, and posttraumatic stress disorder (PTSD). (eftuniverse.com)
  • EFT has met the APA standards as an "efficacious" treatment for phobias, anxiety, depression, and PTSD. (eftuniverse.com)
  • Currently, the Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) advise discontinuing antidepressant treatment 8 weeks after remission of depression . (medscape.com)
  • Are all psychotherapies equally effective in the treatment of adult depression? (bvsalud.org)
  • A reliable, early and less invasive method is needed to assess treatment outcome. (dndi.org)
  • TAK228 is a novel therapy that can be added to standard treatment in the participant population and the aim of the DICE trial is to assess its effectiveness. (biomedcentral.com)
  • OBJECTIVES: To assess the effects of behavioural and pharmacologic interventions for the treatment of ST use. (who.int)
  • During a discussion that followed the presentation, moderator Selina Luger, MD, of the University of Pennsylvania in Philadelphia, asked whether the two treatment groups differed with respect to completion of required therapy. (medpagetoday.com)
  • Treatment success was significantly higher in new smear-positive cases and lower in retreatment cases. (who.int)
  • Among the provinces and regions, treatment success was significantly higher in 4 out of 8 provinces. (who.int)
  • however, fewer data are available on its long-term outcome. (bmj.com)
  • Obviously, the most fundamental use of BHOM is to use the data to track treatment progress on a patient-by-patient basis. (wikipedia.org)
  • The data will be used to develop a predictive model of OUD medication treatment response and outcomes. (nih.gov)
  • Paucity of data has curtailed efforts to improve ABC patient outcomes in NZ. (hindawi.com)
  • We estimated the prevalence, awareness, treatment, and control of high LDL cholesterol using data from a unique local survey of New York City's diverse population. (cdc.gov)
  • TB treatment outcome Pakistan, to use de-identified TB data treatment strategy in 1995 [2]. (who.int)
  • We obtained case-notification and treatment-outcome data from the aggregated national database. (who.int)
  • We collected data from 180 schools, with 45 each randomly assigned for a cross-cutting HE-SP treatments. (who.int)
  • The cephalometric radiograph gradually became the cornerstone of orthodontic diagnosis, and treatment objectives were based on achieving certain final "numbers. (thejcdp.com)
  • COVID-19 has disrupted years of improvement in essential TB services, with reduced access to diagnosis and treatment. (who.int)
  • Socioeconomic Factors in the Diagnosis and Treatment of Malignant Mela" by Julia Griffin, Sarah J. Aurit et al. (unl.edu)
  • HIV RNA testing provides a measure of treatment success and is used as a patient management tool. (biomedcentral.com)
  • With formal assessments of patient needs, the clinician can devise an individualized treatment plan that incorporates these needs and evidence-based practices and principals. (wikipedia.org)
  • Although insufficient evidence exists to demonstrate that the use of conventional drugs adversely affects patient outcomes, long-term use can cause arrhythmia, systemic hypotension, acid-base balance disorders, and other toxic side-effects [ 8 , 9 ]. (hindawi.com)
  • Patient factors that may affect the treatment outcome should be also studied. (who.int)
  • Primary care physicians (PCPs) were trained to deliver evidence-based care, and PCP office-based diabetes self-management education improved patient outcomes. (cdc.gov)
  • Smokers visiting a Web-based cessation program during the New Year period were more likely to register for treatment and differ on several demographic variables, but showed similar patterns of treatment engagement, retention, follow-up, and short-term cessation outcomes compared with participants who visited the site during other periods of the year. (jmir.org)
  • They hope it can become both a treatment for COVID-19 and a way to protect people at high risk of coronavirus infection from becoming ill. (latimes.com)
  • Shahin O, et al "A comparison of treatment outcomes in adolescents and young adults (AYA) with Philadelphia-negative acute lymphoblastic leukemia (ALL) treated with hyperCVAD and pediatric-inspired protocols" SOHO 2023: Abstract ALL-363. (medpagetoday.com)
  • ABSTRACT Measuring treatment outcome is important for successful tuberculosis (TB) control programmes. (who.int)
  • Classification of long-term virologic patterns such as these observed HIV treatment "careers" may provide a suitable framework to identify modifiable factors associated with treatment resilience and failure. (biomedcentral.com)
  • Administration of granulocyte macrophage colony stimulating factor (GM-CSF) after birth raises neutrophil counts but does not improve neonatal or 2-year developmental outcomes. (bmj.com)
  • The suggestion of worse respiratory outcomes in the GM-CSF group at 2 years was replicated at 5 years. (bmj.com)
  • Three of nine modules in the panic disorder treatment and six of nine in the social anxiety disorder treatment showed significant interaction effects. (frontiersin.org)
  • Most impressive in terms of outcomes was applying a co-primary endpoint of symptom resolution, elimination, at 4 weeks which was met, and showing the benefit of acupuncture persisted after ceasing therapy, suggesting acupuncture might change the natural history of the disorder," said Talley, who was not involved in the research. (medpagetoday.com)
  • Effective treatment of HIV since 1996 has reduced morbidity and mortality through virologic suppression. (biomedcentral.com)
  • Continuing antidepressant therapy for 52 weeks, as opposed to stopping it at 8 weeks, was not more beneficial with regard to the primary outcome of occurrence of any mood episode. (medscape.com)
  • However, their applications are often limited by a myriad of factors such as a narrow time window of treatment and a potential risk of cerebral bleeding, resulting in low usage in real-world practices. (biomedcentral.com)
  • Local monitoring of the prevalence, treatment, and control of CHD risk factors is needed for planning and evaluating interventions to prevent disease. (cdc.gov)
  • Both individual and population interventions are needed to reduce transmission, prevent the emergence of drug resistance, and improve outcomes of community ART programs. (biomedcentral.com)
  • Prevention of avoidable visual impairment capitalizes on the availability of known, proven and cost-effective interventions including treatment. (who.int)
  • With the widespread availability of low-cost medicines, intra-ocular lens implants and other treatments, ophthalmic interventions can be highly effective and efficiently delivered. (who.int)
  • In addition to Atz/Bev, there are five other effective systemic agents [sorafenib, lenvatinib, regorafenib, ramucirumab (RAM) and cabozantinib] for advanced HCC, and sequential treatment with these agents is considered important for prolonged therapeutic benefits ( 3 ). (iiarjournals.org)
  • Slightly over half of the exposures were known or expected to not result in serious outcomes. (cdc.gov)
  • To achieve TB eradication in Egypt, efforts should be made to sustain the TB control strategy by improving treatment outcomes and intensifying case finding and surveillance reporting. (who.int)
  • The success of the treatment usually depends on the severity of your fears. (medlineplus.gov)
  • Acute basilar artery thrombosis is an infrequent but catastrophic subtype of posterior circulation ischemic stroke that carries a mortality rate of 80%-90% without treatment. (ajnr.org)
  • NIHSS score at admission and TICI grade were all found to be independently associated with an unfavorable outcome at 3 months. (ajnr.org)
  • Studies have shown that pain acceptance is associated with a better pain outcome. (mdpi.com)
  • Although many studies of treatments for CPHD have been published, no effective treatment has been developed to reduce the rate of mortality or disability caused by CPHD. (hindawi.com)
  • Previous retrospective studies have shown that AYAs have similar or better outcomes with PIPs, Shahin continued. (medpagetoday.com)
  • Here we demonstrate the use of K18-hACE2 mice for studies of COVID-19 disease and treatments. (nature.com)
  • To be designated as "probably efficacious," a treatment must have been shown to be better than a wait list in two studies that meet these criteria, or are conducted by the same research team rather than two independent teams. (eftuniverse.com)
  • The lack of statistical power of comparative outcome studies. (bvsalud.org)