• Some strains of S. epidermidis are highly salt tolerant and commonly found in marine environment. (wikipedia.org)
  • 2021) isolated and identified salt tolerant strains of S. epidermidis (strains ISP111A, ISP111B and ISP111C) from Cliona viridis sponges of the Saint Martin's Island Area of the Bay of Bengal, Bangladesh. (wikipedia.org)
  • This decreased metabolism, in combination with impaired diffusion of antibiotics, makes it difficult for antibiotics to effectively clear this type of infection.S. epidermidis strains are often resistant to antibiotics, including rifamycin, fluoroquinolones, gentamicin, tetracycline, clindamycin, and sulfonamides. (wikipedia.org)
  • Treatment of clinically relevant S . epidermidis infections frequently requires the use of glycopeptides, oxazolidinones or lipopeptide antibiotics, as resistance to beta-lactams is widespread among S . epidermidis strains [ 4 ]. (biomedcentral.com)
  • On the second day, a methicillin resistant S. epidermidis (MRSE) strain was detected in both sets of blood cultures , but the organism was unavailable for toxin testing. (bvsalud.org)
  • NOTE: Methicillin-resistant staphylococci are resistant to cephalosporins, including ceftizoxime. (nih.gov)
  • Staphylococcus epidermidis is salt-tolerant (halophilic) so it will grow on the mannitol salt agar (MSA) Plate and will produce colonies. (chezbebeny.com)
  • Staphylococcus epidermidis belongs to the group of coagulase-negative staphylococci and is a major constituent of the human skin flora [ 1 ]. (biomedcentral.com)
  • To date, few cases of TSS caused by coagulase negative (CoN) staphylococci have been reported in the literature . (bvsalud.org)
  • Coagulase negative staphylococci. (cdc.gov)
  • Although S. epidermidis is not usually pathogenic, patients with compromised immune systems are at risk of developing infection. (wikipedia.org)
  • Staphylococcus epidermidis is a Gram-positive bacterium, and one of over 40 species belonging to the genus Staphylococcus. (wikipedia.org)
  • The high concentration of salt (7.5%) selects for members of the genus Staphylococcus, since they can tolerate high saline levels. (chezbebeny.com)
  • Colony, morphological, physiological, and biochemical characteristics of marine S. epidermidis are shown in the table below. (wikipedia.org)
  • Compared with imipenem, meropenem has slightly increased activity against gram-negative organisms and slightly decreased activity against staphylococci and streptococci. (medscape.com)
  • CASE PRESENTATION We report a case of a 46-year-old man who developed TSS from S. epidermidis. (bvsalud.org)
  • Being part of the normal skin microbiota, S. epidermidis is a frequent contaminant of specimens sent to the diagnostic laboratory. (wikipedia.org)
  • In contrast, nonpathogenic Staph such as Staphylococcus epidermidis (aka Staph epi), the normal flora that grows on human skin, does not ferment mannitol. (chezbebeny.com)
  • A) Structure superposition of the modeled structure of YycG HATPase_c domain of S. epidermidis (blue) with the NMR structure of the homologous domain of EnvZ in E. coli (yellow). (biomedcentral.com)
  • Note: + = Positive, - = Negative, W = Weakly Positive The ability to form biofilms on plastic devices is a major virulence factor for S. epidermidis. (wikipedia.org)
  • An extracellular polysaccharide adhesin represents a key virulence determinant in S. epidermidis and is required for biofilm formation. (nih.gov)
  • Most isolates of both species were strong biofilm producers (92.8% of S. epidermidis and 72.9% of S. haemolyticus). (uanl.mx)
  • Note: + = Positive, - = Negative, W = Weakly Positive The ability to form biofilms on plastic devices is a major virulence factor for S. epidermidis. (wikipedia.org)
  • S. epidermidis is a particular concern for people with catheters or other surgical implants because it is known to form biofilms that grow on these devices. (wikipedia.org)
  • It is sensitive to novobiocin, providing an important test to distinguish it from Staphylococcus saprophyticus, which is coagulase-negative, as well, but novobiocin-resistant. (wikipedia.org)
  • The coagulase-negative staphylococci and, in particular, Staphylococcus epidermidis, have emerged as major nosocomial pathogens associated with infections of implanted medical devices. (nih.gov)
  • Usually an innocuous commensal microorganism on human skin, this member of the coagulase-negative group of staphylococci can cause severe infection after penetration of the epidermal protective barriers of the human body. (nih.gov)
  • Multidrug-resistant coagulase -negative staphylococci represent a real therapeutic challenge. (bvsalud.org)
  • Coagulase negative Staphylococcus spp. (tmcc.edu)
  • Staphylococcus epidermidis & coagulase negative Staphylococcus account for 90% of resident flora. (tmcc.edu)
  • The immunogenic compositions can include immunogenic conjugates of poly-gamma-glutamic acid (such as gammaDLPGA) polypeptides of S. epidermidis , or related staphylococci that express a gammaPGA polypeptide. (nih.gov)
  • 8. A method for producing a Staphylococcus epidermidis polypeptide comprising culturing a cell comprising a recombinant expression vector comprising a nucleic acid encoding SEQ ID NO: 5314 under conditions that permit expression of the polypeptide. (patentsencyclopedia.com)
  • Although S. epidermidis is not usually pathogenic, patients with compromised immune systems are at risk of developing infection. (wikipedia.org)
  • In the U.S. alone, S. epidermidis infections on in-dwelling medical devices, which represent the main type of infection with S. epidermidis , cost the public health system approximately $1 billion per year. (nih.gov)
  • A method of treating an infection caused by a Staphylococcus organism that expresses cap genes is also disclosed. (nih.gov)
  • The method can include selecting a subject who is at risk of or has been diagnosed with the infection by the Staphylococcus organism which expresses gammaPGA from the cap genes. (nih.gov)
  • 14. A method of treating a subject for S. epidermidis infection comprising administering to a subject the immunogenic composition of claim 11, such that treatment of S. epidermidis infection occurs. (patentsencyclopedia.com)
  • 21. A method of treating a subject for S. epidermidis infection comprising administering to said subject the immunogenic composition of claim 18, such that treatment of S. epidermidis infection occurs. (patentsencyclopedia.com)
  • [0002] The invention relates to isolated nucleic acids and polypeptides derived from Staphylococcus epidermidis that are useful as molecular targets for diagnostics, prophylaxis and treatment of pathological conditions, as well as materials and methods for the diagnosis, prevention, and amelioration of pathological conditions resulting from bacterial infection. (patentsencyclopedia.com)
  • Immunogenic compositions and methods for eliciting an immune response against S. epidermidis and other related staphylococci are claimed. (nih.gov)
  • The gammaPGA conjugates elicit an effective immune response against S. epidermidis , or other staphylococci, in subjects to which the conjugates are administered. (nih.gov)
  • Being part of the normal skin microbiota, S. epidermidis is a frequent contaminant of specimens sent to the diagnostic laboratory. (wikipedia.org)
  • Finally, in addition to antibiotic prophylaxis, preventive strategies to control S. epidermidis medical device-related infections are focusing on the development of improved biomaterials and physical electrical barriers to impede bacterial colonisation. (nih.gov)
  • SCCmec type IV was found in 47.2% of the S. epidermidis isolates and SCCmec type V in 14.5% of S. haemolyticus isolates. (uanl.mx)