• Methods: We constructed nanoparticles to fully encapsulate the therapeutic drug (ginsenoside Rg1), which can be transferred into brain tissue via the receptor-mediated transfer of drug-encapsulated nanoparticles. (cbinsights.com)
  • These suggested that mPEG-PLA polymeric micelle nanoparticles had great potential as nanocarriers for effective solubilization of poorly soluble ethaselen and further reducing side effects and toxicities of the drug. (springer.com)
  • Strategies have been advised that nanoparticles can be used to deliver drug/gene to targeted tissues [ 4 ]. (hindawi.com)
  • Drug and gene delivery carriers such as hydrogels and metallic nanoparticles have shown remarkable promise as programmable platforms in the targeted delivery of their payload. (auburn.edu)
  • Because silica nanoparticles are resistant to ultraviolet radiation, adding them to the coating can improve its stability, weather resistance and thixotropy. (iberocruceros.com)
  • Silica nanoparticles have strong chemical stability and are not easy to decompose under ultraviolet light, which meets the requirements of cosmetics and sunscreen products to shield sunlight ultraviolet rays, and the color of the particles is white, so adding it to cosmetics can not only achieve sunscreen effect, but also achieve whitening effect. (iberocruceros.com)
  • Silica nanoparticles not only have high stability, but also have biocompatibility and low toxicity, so they have good application prospects in the field of biomedicine, such as drug controlled release, gene carrier, biosensor and so on. (iberocruceros.com)
  • The fluidity of ranitidine, meglumide and valencil can be changed by adding a small amount of silica nanoparticles to the drugs. (iberocruceros.com)
  • In recent years, there has been a growing interest in the use of nanoparticles as drug carriers to the central nervous system via blood-brain barrier. (umk.pl)
  • The usage of nanoparticles implies many advantages, such as non-invasive, low cost, good biodegradability, stability, ability to carry various types of agents, selectivity and ability to control drug release. (umk.pl)
  • Due to their small size and large surface area-to-volume ratio, nanoparticles exhibit high reactivity, greater stability and adsorption capacity. (bvsalud.org)
  • Silver nanoparticles (AgNPs) are preferable for drug delivery applications due to their unique properties and less toxicity. (edu.ng)
  • It is difficult today to appreciate the number of potential drugs that have been discarded as a result of limited efficacy due to inappropriate excipients. (smw.ch)
  • A molecular basis for innovation in drug excipients. (smw.ch)
  • The powder-based technology is made up of particles which are built using a unique combination of a drug, carrier materials and, optionally, other excipients such as a permeability enhancer. (orexo.com)
  • Applications of lithium stearate include drug carriers, excipients, and stabilizers. (replaceuac.com)
  • Carrier would change a drug's physical attributes in order to increase its fat or water solubility or to allow site-directed delivery. (ijpsonline.com)
  • As a result, Precirol® was selected as the best lipid base for the SLN formulation based on Hildebrand-Hansen solubility parameters, in which SLN-NOS 1 % had the best zeta potential (-35.74 ± 2.59 mV), average particle size (245.66 ± 17 nm), polydispersity index (PDI, 0.226 ± 0.09), high entrapment efficiency (89.77 %), and ICH-based stability results. (bvsalud.org)
  • Nano-carriers enhance drugs stability and solubility and prevent their rapid degradation. (edu.ng)
  • Our team will analyze the properties of the drug, such as solubility, stability, and desired release profile, to recommend the most suitable carrier. (dubaitruck.com)
  • It can enhance the stability of medications and also improve their taste and solubility. (replaceuac.com)
  • Subsequently, rhein hydrogels alleviate neuroinflammation with a long-lasting effect and little cytotoxicity compared to the equivalent free-drug in vitro. (nature.com)
  • Methods: Sitagliptin liposomes were prepared by the ethanol injection method and were evaluated for various physicochemical properties such as visual appearance, particle size distribution, zeta potential, % drug entrapment efficiency, % drug loading capacity and in vitro drug release studies. (benthamscience.com)
  • The in vitro cytotoxicity analysis of the Ptx loaded RGO nanodispersion revealed the potential of the nanodispersion as a suitable drug carrier. (nottingham.ac.uk)
  • The rheological characteristics and in vitro stability were investigated. (ku.dk)
  • Both rheological and in vitro stability studies suggested that cubosome-loaded 17% (w/v) P407 with 25R4 in 1:1 molar ratio may have a potential as sustained release delivery system. (ku.dk)
  • In previous work, our group has prepared micellar ethaselen formulation employing PLA-based copolymers and characterized its drug loading contents and stability (data not shown), which have demonstrated the compatibility between the core of micelles and the ethaselen molecules. (springer.com)
  • The prodrug approach using various carriers has evolved as a significant tool in surmounting different obstacles in relation to drug formulation and targeting. (ijpsonline.com)
  • Results: The optimized formulation (L-3) showed round-shaped distinct particles with good stability. (benthamscience.com)
  • Formulation and evaluation of gliptin loaded polymeric nanomicelles for controlled drug delivery. (benthamscience.com)
  • These properties enable formulation of drugs in a manner that allows for a faster onset and a higher bioavailability. (orexo.com)
  • Drug absorption is determined by the drug's physicochemical properties, formulation, and route of administration. (msdmanuals.com)
  • Additionally, new drug delivery systems - e.g., based on polymeric materials - will most likely enlarge the spectrum of future proteinic dosage forms, where today solutions and lyophilized products take center stage. (uni-muenchen.de)
  • Excipient Stability in Oral Solid Dosage Forms: A Review. (smw.ch)
  • This investigation demonstrated the potential of the exceptionally stable RGO nanodispersion in nano drug delivery and electrochemical sensing applications. (nottingham.ac.uk)
  • Electrochemical stability: The ability of anode materials to stabilize their structure and reactivity while the battery is charging or discharging. (tungstenmolybdenummetals.de)
  • Although lithium titanate has good electrochemical stability, it is expensive. (tungstenmolybdenummetals.de)
  • These new materials will lead to the development of future lithium batteries anode materials due to their higher reversible capacitance, improved electrochemical stability, and lower cost. (tungstenmolybdenummetals.de)
  • This material offers high reversible capacitance, high electrochemical stabilities and a long life. (tungstenmolybdenummetals.de)
  • Prodrugs are derivatives of drug molecules that are pharmacologically inactive but require either chemical or enzymatic transformation to release the active drug in vivo in order to exert a pharmacological effect. (ijpsonline.com)
  • In addition, xenon imaging also has analytical potential because molecules that interact with xenon can be used as drug carriers that can now be localized and characterized using MRI. (leibniz-gemeinschaft.de)
  • The numbers describe the exact exchange rate between xenon and the molecules, enabling conclusions to be drawn on aspects such as the stability of a molecule as a drug carrier. (leibniz-gemeinschaft.de)
  • We showed that the activation energy greatly distributes along the molecules and enzymes with different thermal stabilities might be present within the population. (tufts.edu)
  • Protein AgNPs are versatile nano-carriers as they provide the anchoring layer for drug molecules to be transported into cells. (edu.ng)
  • Cell membranes are biologic barriers that selectively inhibit passage of drug molecules. (msdmanuals.com)
  • MXene material is characterized with high specific surfaces, chemical stability, biocompatibility as well as tunable physical characteristics. (tfmpage.com)
  • Most surfactants have good chemical stability under conventional conditions and are not easy to decompose and deteriorate. (iberocruceros.com)
  • This chemical stability makes surfactants effective for long-term use in many fields. (iberocruceros.com)
  • They can effectively reduce the surface tension of liquids, change the surface properties of liquids, promote intermixing and emulsification of liquids, improve the wetting and penetration ability of liquids, produce rich foam, and have characteristics such as chemical stability. (iberocruceros.com)
  • The lithium stearate also has a good chemical stability, and is resistant to acids and bases, as well as oxidants, reductants and reducing agents. (replaceuac.com)
  • MXene material is characterized by a large specific surface, high chemical stability, biocompatibility and tunable properties. (eduloc.com)
  • Apomyoglobin (apoMb), a model protein in biochemistry , exhibits a strong propensity to bind various ligands, which makes it a good candidate as a carrier of bioactive hydrophobic drugs. (cea.fr)
  • The stability of its hydrophobic pocket determines its potential as a carrier of bioactive compounds. (cea.fr)
  • High pressure (HP) is a potent tool for studying protein stability, revealing the specific role of hydrophobic cavities in unfolding. (cea.fr)
  • Liposomes act as drug carriers for entrapment of hydrophilic and hydrophobic drugs. (benthamscience.com)
  • However, clinical researchers continually find that the involvement of drug carriers may lead to poor biocompatibility and biodegradability, low loading efficacy, and potential side effects. (nature.com)
  • Biocompatibility results supported the use of the G-Au nanocomposite system for anticancer applications such as drug delivery, imaging, etc. (nottingham.ac.uk)
  • Intranasal administration is a potential route associated with high drug transfer from nose to brain and drug bioavailability. (wikipedia.org)
  • Drug delivery through nasal cavity increases drug bioavailability and lowers risk of systemic exposure. (wikipedia.org)
  • The delivery systems between neutral to acidic pH is ideal for high drug bioavailability following intranasal administration. (wikipedia.org)
  • Clofazimine, an anti-leprosy drug, has been anticipated for a candidate to treat tuberculosis, cryptosporidiosis, and coronavirus infection, but its low oral bioavailability is considered a reason for its limited activity. (bvsalud.org)
  • Overview of Pharmacokinetics Pharmacokinetics, sometimes described as what the body does to a drug, refers to the movement of drug into, through, and out of the body-the time course of its absorption, bioavailability, distribution. (msdmanuals.com)
  • A series of monomethoxy poly(ethylene glycol)-poly(lactide) (mPEG-PLA) diblock copolymers were synthesized, and mPEG-PLA micelle was fabricated and used as a nanocarrier for solubilization and delivery of a promising anticancer drug ethaselen. (springer.com)
  • The excellent stability at physiological pH promotes its utilization of RGO dispersion as a carrier of Paclitaxel (Ptx) - an anticancer drug. (nottingham.ac.uk)
  • In addition the complex is one of the most useful carrier material for new drug and gene delivery systems as well as for gene therapy. (scialert.net)
  • With the development of nanotechnology, nanocarriers have been increasingly used for curative drug/gene delivery. (hindawi.com)
  • As a novel theranostic system, nanocarriers hold great promise for ultrasound molecular imaging, targeted drug/gene delivery, and therapy. (hindawi.com)
  • These effects may induce transient membrane permeabilization (sonoporation) on a single cell level, cell death, and disruption of tissue structure, ensuring noninvasive, targeted, and efficient drug/gene delivery and therapy. (hindawi.com)
  • In this review, we explore the research progress and application of ultrasound-mediated local drug/gene delivery with nanocarriers. (hindawi.com)
  • Nanoparticle, used as a drug/gene delivery vehicle, can not only target specific cells and tissues, but also retain the biological activity of the drug/gene during transport. (hindawi.com)
  • Ultrasonic drug and gene delivery from nanocarriers have tremendous potential because of the wide variety of drugs and genes that could be delivered to targeted tissues by fairly noninvasive means [ 7 ]. (hindawi.com)
  • We employ 2D materials such as graphene oxide, MoS 2 , MXenes, black phosphorus, etc., in combination with biopolymers or biominerals (CaCO 3 ) for developing degradable biomaterials for Drug/Gene Delivery, Nanotheranostics, Biomimetic Systems, and Antimicrobial Coatings to tackle multidrug resistance bacteria including pandemic virus-like COVID-19. (iisertvm.ac.in)
  • Its drug release characteristics perform well in photothermal therapy, indicating that black phosphorus nano drugs can improve the biological safety and applicability of drugs in new tumor targeted therapy. (frontiersin.org)
  • Meanwhile, the mesoporous carbon shell and hydrophilic surface functional groups endow the hybrid NPs with high loading capacity (835 mg g −1 ) for the anti-cancer drug doxorubicin and excellent stability in aqueous solutions. (rsc.org)
  • The presence of 25R4 allowed the development of formulations that were free flowing liquid at working temperature (22 °C), gelled at body temperature (37 °C) and had improved stability in an aqueous environment. (ku.dk)
  • Most drugs are weak organic acids or bases, existing in un-ionized and ionized forms in an aqueous environment. (msdmanuals.com)
  • Prodrugs have better delivery properties that surpass the parent drug molecule [ 1 ]. (ijpsonline.com)
  • Hence, search for new lead molecule/bioactive and rational delivery of the existing drug (for better therapeutic effect) to the site of action is the need of the hour. (hindawi.com)
  • Self-assembling natural drug hydrogels formed without structural modification and able to act as carriers are of interest for biomedical applications. (nature.com)
  • Nanomaterials have demonstrated a wide range of applications and recently, novel biomedical studies are devoted to improving the functionality and effectivity of traditional and unmodified systems, either drug carriers and common scaffolds for tissue engineering or advanced hydrogels for wound healing purposes. (researchgate.net)
  • This hydrogel shows excellent stability, sustained release and reversible stimuli-responses. (nature.com)
  • The weak acidic drugs (indomethacin, ibuprofen and naproxen) with amorphous polymeric carrier Eudragit E (EPO) were chosen as suitable combinations for study. (manufacturingchemist.com)
  • Dr Tian said: "The solid-state properties of ball-milled samples and the dissolution/melting behaviours of crystalline drug in the polymeric matrix, as a function of temperature, were analysed using small angle/wide angle X-ray scattering. (manufacturingchemist.com)
  • The study was able to directly observe the temperature dependences of the X-ray scattering pattern for the crystalline drugs (IND, NPX and IBU) in the presence of a polymeric carrier. (manufacturingchemist.com)
  • Over the past few decades, the field has seen breathtaking advancements with improved drug formulations, release mechanisms, delivery materials, and administration routes. (wikipedia.org)
  • The extract was incorporated into different formulations, and a stability study was conducted with the emulsion chosen. (ijpc.com)
  • Moreover, common targeted therapeutic drug formulations have weak stability in malignant tumor leukemia, and their application effects are limited. (frontiersin.org)
  • The dispersions were fully characterized by means of differential scanning calorimetry and broadband dielectric spectroscopy, and the drug release profile was measured in a simulated body fluid. (ibecbarcelona.eu)
  • Between 1950s and 1980's, there were four drug release systems developed for oral and transdermal applications: dissolution, diffusion, osmosis, and ion-exchange controlled release. (wikipedia.org)
  • study deformable liposomes as potential carriers for transdermal drug delivery. (ddw-online.com)
  • Tween ® 80 and sodium deoxycholate, on (i) the physical, mechanical, and biological properties of ultradeformable vesicles, and (ii) the administration of naproxen sodium-loaded multidrug ultradeformable vesicles for the transdermal route in order to obtain therapeutically meaningful drug concentrations in the target tissues and to potentiate its anti-inflammatory effect by association with the antioxidant drug idebenone. (mdpi.com)
  • Liposomes serve as promising active carriers of drugs to posterior segment eye disorders due to improvement in intravitreal half-life and targeted sustained drug delivery to the retina. (benthamscience.com)
  • Recent applications of liposomes in ophthalmic drug delivery. (benthamscience.com)
  • The effect of carbopol 940 on physical stability of palm olein emulsions stabilised by span and tween surfactants. (iium.edu.my)
  • The two-dimensional nano drug carrier has high safety and effectiveness in drug delivery, and its targeted treatment effect on acute T lymphoblastic leukemia cells is obvious. (frontiersin.org)
  • The objective of this review is to provide the researchers with a compilation of which carriers would be suitable for prodrug synthesis and what would be their benefits. (ijpsonline.com)
  • Intranasal drug delivery occurs when particles are inhaled into the nasal cavity and transported directly into the nervous system. (wikipedia.org)
  • The particles are presented as an amorphous composite of the various ingredients providing for excellent chemical and physical stability. (orexo.com)
  • Additionally, these biological materials from drug carriers require complex syntheses and are relatively expensive 12 , which create great obstacles for effective clinical application. (nature.com)
  • Additionally, neuroprotectants could mitigate the ischemia/reperfusion injury, including edaravone and fingolimod, 3 but their clinical effects cannot achieve the desired condition, primarily due to the rigid blood-brain barrier (BBB) that limits drug delivery to the ischemic regions. (cbinsights.com)
  • Additionally, tracking technologies allow both carriers and customers to monitor shipments in real time. (dubaitruck.com)
  • Evaluation of the ability of peroxidases secreted by immune cells to oxidize/degrade the emerging 2D materials such as black phosphorus, MXenes, etc. and intracellular (macrophages) stability of 2D materials and their cytotoxicity. (iisertvm.ac.in)
  • A lack of knowledge about natural drug gels limits there current application. (nature.com)
  • One of them is graphite-based material, which has high reversible capacities and good stability electrochemically, but costs a lot. (tungstenmolybdenummetals.de)
  • Great potential has been shown by nanogels in many fields including delivery of genes, chemotherapy drugs, diagnosis, targeting of specific organs and several others. (nih.gov)
  • Templated polymer systems have unique 'trained' binding characteristics that make them of high interest within chromatography, sensors, diagnostic devices, and drug delivery carriers. (auburn.edu)
  • Therefore, based on the characteristics of black phosphorus two-dimensional nanomedicine, experimental designs were conducted on its nanosheet preparation, polyethylene glycol modification, and anti-tumor drug loading. (frontiersin.org)
  • This review focuses mainly on different types of nanogels, methods of preparation including methods of drug loading, different modes of biodegradation mechanisms as well as main mechanisms of drug release from nanogels. (nih.gov)
  • More importantly, the hybrid NPs can absorb and convert near-infrared (NIR) light to heat due to the existence of CDs, and thus, can realise NIR-controlled drug release and combined photothermo/chemotherapy for high therapeutic efficacy. (rsc.org)
  • These prodrugs subsequently undergo enzymatic or non-enzymatic cleavage to release the active drug moiety (figure 1) [ 12 , 13 ]. (ijpsonline.com)
  • L-3 followed Korsmeyer- Peppas model with fickian diffusion transport of drug release giving n' (0.3094), r2 (0.9753), with 83.78 ± 0.97% of sustained drug release. (benthamscience.com)
  • The potential approach is to develop particular carriers which can facilitate the release of the payload locally in tissue by internal or external stimuli (such as heat, light, ultrasound, etc. (hindawi.com)
  • Ultrasound is a noninvasive and visual theranostic modality that can be used to track drug carriers, trigger drug release, and improve local drug sediment with high spatial precision [ 5 , 6 ]. (hindawi.com)
  • Furthermore, as targeted delivery carriers, gene/drug-loaded nanocarriers can release their associated payload upon insonation. (hindawi.com)
  • Its low toxicity, high efficiency, and controllable drug release advantages make it have good application effects. (frontiersin.org)
  • Experimental analysis was also conducted on the characterization ability, drug release, and targeted therapy of nanomedicine. (frontiersin.org)
  • The maximum drug release rates of BP-PEG-DOX-NIR reached 33.23% and 28.67% at temperatures of 35°C and 45°C, with differences of over 10% compared to the non laser group. (frontiersin.org)
  • Drug delivery systems seem to be a new method for improving drug targeting and release into cells, bringing new opportunities for improving drug efficiency and avoiding potential side effects. (frontiersin.org)
  • All weight vests come with durable Duraflex® hardware, a laser-cut micro-loop web platform, and an extended drag handle and quick release system. (roguefitness.com)
  • Though several studies have been carried out on various prodrugs, surprisingly very few reviews on different carriers, which can be used for prodrug synthesis were published to date. (ijpsonline.com)
  • Around 10 % of marketed medicines can be categorized as prodrugs currently, and also that during 2008, 33 % of approved small molecular weight drugs were prodrugs [ 5 - 7 ]. (ijpsonline.com)
  • Carrier-linked prodrugs are for drugs with major drawbacks, which are linked to a nontoxic carrier or promoiety through covalent linkage to change or get rid of their undesirable physicochemical properties. (ijpsonline.com)
  • When utilizing other routes of administration to target the brain, drug adsorption is low due to issues with systemic circulation effects and blood brain barrier. (wikipedia.org)
  • Nanomaterials in combination with biomolecules are used in drug delivery, imaging and sensing applications by targeting the overexpressed cancer proteins such as folate receptors (FR), to control the disease from progressing to advanced levels. (nottingham.ac.uk)
  • Chakraborty A, Dhar P. A review on potential of proteins as an excipient for developing a nano-carrier delivery system. (smw.ch)
  • Herein, the development of a simple method for the synthesis of egg proteins stabilized AgNPs and their use as nano-carrier for hesperidin is reported. (edu.ng)
  • Current findings suggest a facile approach for proteins stabilized AgNPs and their potential as effective nano-carrier for enhancing the bactericidal activity of hesperidin. (edu.ng)
  • Most of the circulating testosterone is bound to carrier proteins (SHBG = sex hormone-binding globulin). (cdc.gov)
  • Drug resistance is a main obstacle for curative cancer chemotherapy. (hindawi.com)
  • Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance. (cdc.gov)
  • Targeting the olfactory region increases efficiency of nose-to-brain drug delivery. (wikipedia.org)
  • Nanoporous complexes can increase the efficiency with which drugs can penetrate the blood-brain barrier and reach target organs. (cbinsights.com)
  • Targeted therapy uses targeted drugs to maintain a high concentration of the drug in the tumor area, improving the killing efficiency of cancer cells while avoiding damage to other normal cells. (frontiersin.org)
  • Efficiency is another key aspect addressed by pharmaceutical carrier services. (dubaitruck.com)
  • Besides, nanocarriers decorated with targeting moiety can adhere to targeted tissues, which can promote intracellular uptake of drug delivery vehicles. (hindawi.com)
  • Nanogels have outstandingly high stability, drug loading ability, biologic consistence, good permeation capability and can be responsive to environmental stimuli. (nih.gov)
  • From a molecular biology point of view this nano-scale self-assembling superstructure could increase the stability of DNA against the nucleases during collagen diseases and the growth of collagen fibrils in the presence of DNA. (scialert.net)
  • In situ visible absorption study of BV chromophore confirmed the ability of Zn 2+ to increase the stability of apoMb-BV complex under HP: the onset of complex dissociation is shifted by ∼100 MPa in presence of Zn 2+ . (cea.fr)
  • Nanocarriers can pass through blood capillary walls and cell membrane walls to deliver drugs. (hindawi.com)
  • Although the system of ultrasound-mediated drug delivery with nanocarriers has many advantages, there are still many challenges. (hindawi.com)
  • Introduction and purpose: Blood-brain barrier (BBB) consists of capillary endothelium, in which there are three types of intercellular junctions - adherent, tight and gap junctions.Efficient therapy involves delivering a therapeutic dose of drug into a specific site in the body, and maintaining this dose for adequate time afterwards. (umk.pl)
  • Nano carriers for drug transport across the blood-brain barrier. (umk.pl)
  • Tam VH, Sosa C, Liu R, Yao N, Priestley RD. Nanomedicine as a non-invasive strategy for drug delivery across the blood brain barrier. (umk.pl)
  • Azad TD, Pan J, Connolly ID, Remington A, Wilson CM, Grant GA. Therapeutic strategies to improve drug delivery across the blood-brain barrier. (umk.pl)
  • How to overcome potential drawbacks such as sample-membrane interactions by adequate choice of the ultrafiltration membrane as well as carrier liquid composition was illustrated. (uni-muenchen.de)
  • Smart materials that can be triggered by external stimuli are seen with high potential for innovative treatments and improved drug delivery systems by regulatory agencies like the FDA and EMA. (researchgate.net)
  • They can be adsorbed on gas-liquid or liquid-liquid interfaces, thus changing the properties of the interface and affecting its stability, wettability, viscosity, surface potential, etc. (iberocruceros.com)
  • One in 30 Ashkenazi Jews is presumed to be a carrier, which results in a potential disease incidence of 1 in 3600 live births to this population. (medscape.com)
  • Drug delivery is a process of administering therapeutics to treat human diseases. (wikipedia.org)
  • Recent work by a team of researchers at Queen's University Belfast and University College London has demonstrated a recently developed strategy for the manufacture of a high drug loaded amorphous solid dispersion (HDASD) using a hot-melt extrusion (HME) based platform 1 . (manufacturingchemist.com)
  • Dr Tian said: 'The information we collected is particularly useful for the design of hot-melt extrusion processes, where a fully amorphous solid dispersion can be generated at conditions that are significantly lower than the melting point of the crystalline drug, and at much higher drug loadings. (manufacturingchemist.com)
  • 1. Tian, Y., E. Jacobs, D.S. Jones, C.P. McCoy, H. Wu, G.P. Andrews, The design and development of high drug loading amorphous solid dispersion for hot-melt extrusion platform, International Journal of Pharmaceutics (2020). (manufacturingchemist.com)
  • MXene material can be used to carry drugs and as bio-imaging agent in the biomedical industry for drug therapy, medical imaging diagnosis and other purposes. (tfmpage.com)
  • Nanogels have attracted considerable attention as nanoscopic drug carriers, particularly for site-specific or time-controlled delivery of bioactive mediators. (nih.gov)
  • Historically however, amorphous drug compositions were found to be both chemically and physically unstable and therefore to degrade during storage. (orexo.com)
  • They have been applied in a wide range of biological systems ranging from drug delivery to tissue engineering. (springer.com)
  • MXene material can be used to remove heavy metals and organic pollutants from water, and also as a carrier for catalysts in catalytic reactions. (tfmpage.com)
  • The factor XIII zymogen circulates in plasma as a tetramer composed of 2 catalytic A subunits and 2 carrier B subunits (A 2 B 2 ). (medscape.com)
  • The mechanism of transport through porins is of utmost and direct interest for drug discovery, extending toward nanotechnology applications for blue energy, separations, and sequencing. (ibecbarcelona.eu)