• organ
  • Loss of splenic tissue due to surgical removal may occur later in life as a result of trauma that causes rupture of the organ. (medscape.com)
  • Although considered a nonvital organ, and once thought to serve no practical purpose, the spleen is now recognized as an important secondary lymphoid organ in immune defense and as a filter for the bloodstream. (medscape.com)
  • After birth, the spleen has several important functions as a secondary lymphoid organ and as a reservoir and filter for cells and platelets. (medscape.com)
  • constipation
  • Physical factors may cause ischuria, constipation, as well as numerous spleen-related diseases such as hypersplenism, thrombocytopenia, and lymphoma. (wikipedia.org)
  • fixation
  • In this case we describe a more elegant, simpler method for splenic fixation that in short term follow up appears to be successful. (sages.org)
  • autosplenectomy
  • In sickle cell disease, repeated splenic infarctions lead to a non-functional spleen (autosplenectomy). (wikipedia.org)
  • Autosplenectomy is the process where the spleen loses its function due to multiple and repeated infarctive episodes, as in sickle hemoglobinopathies. (medscape.com)
  • rupture
  • In cases where the spleen is enlarged due to illness (mononucleosis), trivial activities, such as leaning over a counter or straining while defecating, can cause a rupture. (wikipedia.org)
  • platelets
  • The spleen participates in the destruction of all 3 blood elements (erythrocytes, leukocytes, and platelets) when they reach senescence. (medscape.com)
  • left upper quadrant
  • Those that have been published in both populations typically describe the formation of a mesh bag around the spleen which is then fixed into the left upper quadrant. (sages.org)
  • colon
  • The natural laxity of the peritoneum as well as mobilization of the descending colon allow for the spleen to be placed in a near anatomic position in the retroperitoneum while reducing the risk of internal hernia formation or adhesive disease due to intraperitoneal mesh. (sages.org)
  • retention
  • The peritoneum was then closed with a combination of surgical clips and running suture over the spleen ensuring retention of the spleen in the preperitoneal pocket. (sages.org)
  • enlargement
  • This will clearly show enlargement of the spleen and the spleen being out of position of its normal alignment. (epainassist.com)
  • Occasionally, the spleen may be removed to address the sheer mass effect of a massive enlargement (such as in storage disorders), which can cause mass effects. (medscape.com)