• Alzheimer's
  • We and others have examined patients with various neurodegenerative and behavioral neurological conditions, such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Alzheimer's disease (AD) and Autistic Spectrum Disorders ([ASD], including Autism, Attention Deficit Disorder, Asperger Syndrome), and found evidence for systemic intracellular bacterial and viral infections in a majority of patients. (townsendletter.com)
  • They include: Alzheimer's disease Acute disseminated encephalomyelitis Viral meningitis Multiple sclerosis Bell's palsy Neuroborreliosis presenting with symptoms consistent with amyotrophic lateral sclerosis has been described. (wikipedia.org)
  • New research from the University of Toronto Mississauga definitively puts to rest a theory that Lyme disease causes Alzheimer's. (iospress.nl)
  • While researching his book " The Alzheimer's Epidemic-Searching for Causes and a Cure " (Emeritus Books), U of T Mississauga Professor Emeritus Danton O'Day was intrigued to discover studies and popular professional opinion supporting a potential link between Lyme disease and Alzheimer's deaths. (iospress.nl)
  • Alzheimer's disease affects 750,000 Canadians. (iospress.nl)
  • Alzheimer's disease causes a similar loss of cognitive ability and, eventually, death. (iospress.nl)
  • In contrast, the causes of Alzheimer's disease remain unknown and there is no cure. (iospress.nl)
  • Together with Andrew Catalano , a recent PhD graduate from O'Day's research group who is now a post-doctoral fellow at City College of New York, O'Day compared data to see if states with high incidences of Lyme disease also showed a high incidence of deaths related to Alzheimer's. (iospress.nl)
  • The pair found, in fact, that the 13 states with the highest incidence of Lyme disease actually reported the lowest number of deaths due to Alzheimer's. (iospress.nl)
  • Furthermore, seven of the states with high incidences of Alzheimer's deaths were among the 13 states with the lowest incidence of Lyme disease. (iospress.nl)
  • Statistical analyses revealed a complete lack of correlation between the two diseases, strongly suggesting that Lyme disease could not be the cause Alzheimer's," O'Day said. (iospress.nl)
  • Because of this growing impact Alzheimer's disease will have in Canada and world-wide, we need to understand the true factors that underlie the disease," said O'Day. (iospress.nl)
  • We need to quickly rule out concerns, like Lyme disease, that unnecessarily cause widespread fear and interfere with attempts to fully understand the causes of Alzheimer's disease. (iospress.nl)
  • The research, which was published in the August 2014 issue of the Journal of Alzheimer's Disease , was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC). (iospress.nl)
  • antibiotics
  • In the US, neuroborreliosis is typically treated with intravenous antibiotics which cross the blood-brain barrier, such as penicillins, ceftriaxone, or cefotaxime. (wikipedia.org)
  • However, about 10-15% of patients with Lyme arthritis fail the initial course of antibiotics, and some of those develop a chronic inflammatory arthritis optimally treated with local or systemic immunosuppressive agents. (springer.com)
  • 11 In contrast, if the SF-36 was used to determine Quality of Life (QOL) in post-Lyme patients, the average SF-36 physical component summary (40±9, range 29-44) and mental component summary (39±14, range 23-46) of the QOL assessment were worse than the general USA population, and they could be significantly improved by anti-Lyme antibiotics (46% versus 18%, p =0.007). (blogspot.com)
  • Lyme disease can be easily detected and cured with antibiotics," O'Day said. (iospress.nl)
  • The treatment is done differently depending on the stage of the disease and the severity of injuries, being used antibiotics like Doxycycline, Amoxicillin, Erythromycin or Penicillin. (readbyqxmd.com)
  • Africa
  • With so many vectors, the underlying assumption behind this checklist is that Lyme is not rare in North America, Europe, South America, Russia, Africa or Asia. (lymebook.com)
  • The disease is rarely detected in northern Africa and Mediterranean countries ( 3 , 6 , 7 ). (cdc.gov)
  • TBRF
  • In TBRF, the spirochetes are transmitted via the bite of an infected tick, whereas, in LBRF, contact with hemolymph from the human body louse (eg, from scratching-induced louse crushing) is the mode of spirochete transfer. (medscape.com)
  • immunological
  • 1 In addition to genetic changes and changes in gene expression, it is thought that nutritional deficiencies, head trauma, environmental toxins, chronic bacterial and viral infections, autoimmune immunological responses, vascular diseases, accumulation of fluid in the brain, changes in neurotransmitter concentrations, and other causes are involved in various neurodegenerative diseases. (townsendletter.com)
  • manifestations
  • The results were compared to other chronic illnesses where neurological manifestations are often found, such as Chronic Fatigue Syndrome/Myalgic Encephlomyopathy (CFS/ME), Fibromyalgia Syndrome (FMS), Lyme disease (LD), and Gulf War illnesses. (townsendletter.com)
  • In addition, other chronic illnesses where neurological manifestations are routinely found, such as fatiguing and autoimmune diseases, Lyme disease and Gulf War illnesses, also show systemic bacterial and viral infections that could be important in disease inception, progression or increasing the types/severities of signs and symptoms. (blogspot.com)
  • epidemic
  • Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. (springer.com)
  • 1975
  • Lyme disease was diagnosed as a separate condition for the first time in 1975 in Old Lyme, Connecticut. (wikipedia.org)
  • It was first identified in 1975 in the town of Old Lyme, CT after an outbreak of juvenile rheumatoid arthritis. (davidson.edu)
  • patients
  • Patients with neurodegenerative diseases and behavioral disorders often have systemic bacterial, viral, and/or fungal infections that are important in disease progression and severity. (townsendletter.com)
  • showed that patients with neuroborreliosis demonstrate a blood brain barrier disturbance with 62 % showing an elevated albumin ratio and 60 % revealing an increased IgG index, indicative of intrathecal IgG synthesis. (upmc.edu)
  • Use of bisphosphonates in patients with conditions or diseases affecting renal function is not recommended. (issuu.com)
  • Antibiotic treatment duration and long-term outcomes of patients with early Lyme disease from a Lyme disease-hyperendemic area. (springer.com)
  • Although most patients with Lyme/tick-borne disease do not become violent, a small percent of patients who become infected develop a type of neurological dysfunction that can increase their risk of aggressiveness. (psychologytoday.com)
  • In working with a number of patients with Lyme/tick-borne diseases it is apparent to many clinicians these conditions can cause reduced frustration tolerance, irritability, depression , cognitive impairments and mood swings, but more significantly, in a few patients, suicidal and aggressive tendencies. (psychologytoday.com)
  • The presence of B.bissettii as a single strain in patients provides strong support of the factthat B. bissettii might be a causative agent of the disease. (borrelioosi.net)
  • 2016
  • Lyme Disease Differential Diagnoses: Diagnostic Considerations Updated: Mar 14, 2016 CDC Two-step Laboratory Testing Process Page last reviewed: March 4, 2015. (wikipedia.org)
  • laboratory
  • In Lyme disease, much debate exists about laboratory kits, the alteration of kits to have fewer possible bands, and which labs are optimally sensitive and specific. (lymebook.com)
  • neurological disease
  • Can microbes and immune reactions to them actually contribute to cognitive decline, degenerative neurological disease, developmental disabilities, mental illness, personality changes and, at the most extreme, even violent and criminal behavior? (psychologytoday.com)