• spectroscopy
  • J. F. J. Todd, "Recommendations for nomenclature and symbolism for mass spectroscopy," Pure and Applied Chemistry , vol. 63, pp. 1541-1566, 1991. (hindawi.com)
  • Lipidomics is a relatively recent research field that has been driven by rapid advances in technologies such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, fluorescence spectroscopy, dual polarisation interferometry and computational methods, coupled with the recognition of the role of lipids in many metabolic diseases such as obesity, atherosclerosis, stroke, hypertension and diabetes. (wikipedia.org)
  • In modern times, H-D exchange has primarily been monitored by the methods: NMR spectroscopy, mass spectrometry and neutron crystallography. (wikipedia.org)
  • spectra
  • The reference protein method, which was originally developed to correct ESI mass spectra for the occurrence of nonspecific ligand-protein binding, was shown to reliably correct liquid sample DESI mass spectra for nonspecific binding. (springer.com)
  • After preliminary analysis by positive and negative modes, samples and mixtures of standards were derivatized by methylation to minimize ionization sites and reanalyzed.Positive ionization was less effective and produced more complex spectra than negative ionization. (usgs.gov)
  • Since the weight average molecular weight decreased, it is likely that aggregate formation in the fulvic acid was present prior to derivatization, rather than multiple charging in the mass spectra. (usgs.gov)
  • spectrometer
  • The mass spectrometer includes a mass analyzer held in a vacuum chamber. (patents.com)
  • A versatile IR-MALDESI MSI source was designed and implemented, which is currently coupled to a high resolving power hybrid Quadrupole-Orbitrap mass spectrometer. (wikipedia.org)
  • ambient
  • Performing ionization in an ambient environment, this technique requires little sample preparation and no additional matrix, and can be performed on natural, uneven surfaces. (springer.com)
  • Imaging
  • Using the IR-MALDESI imaging source, a variety of dye classes were analyzed from various fabrics with little to no sample preparation allowing for the identification of the dye mass and in some cases the fiber polymer. (wikipedia.org)
  • organic
  • Zare used two-step laser mass spectrometry (L2MS), a technique that is particularly sensitive to organic molecules, to examine samples from the interior of the meteorite. (wikipedia.org)
  • 1990s
  • By the end of the 1990s, Smith's achievements included the electrodynamic ion funnel and a micro-dialysis device for the rapid purification of samples analyzed using mass spectrometry. (wikipedia.org)
  • In the late 1990s, Smith's group was also extensively involved in the development and application of Fourier transform ion cyclotron resonance (FTICR) mass spectrometry, which provided the basis for much greater MS resolution and mass measurement accuracy, and particularly in the development of these technologies for applications in proteomics. (wikipedia.org)
  • source
  • The ablated material is captured in an exposed flowing solvent stream that carries the ablated material to the electrospray source. (biomedsearch.com)
  • M. Yamashita and J. B. Fenn, "Electrospray ion source. (hindawi.com)
  • A water cooled Peltier thermoelectric plate is used to control the sample temperature (−10 °C to 80 °C). The IR-MALDESI source is currently used to investigate the fundamentals of the ionization process, in addition to being routinely employed for visualizing analyte distributions in biological, forensic, and pharmaceutical samples. (wikipedia.org)
  • deconvolution
  • The abundance of ten fatty acyl chains at 46 TAG masses (mass-to-charge ratio, m/z) were determined after isotopic deconvolution and correction by adjustment factors at each TAG mass. (osti.gov)