• ions
  • The plume of desorbed material interacts with an orthogonal electrospray plume where desorbed compounds partition into charged electrospray droplets and ions are generated by an ESI-like process that are sampled by a mass spectrometer. (wikipedia.org)
  • The technique called electrospray-assisted laser desorption/ionization (ELDI) uses an ultraviolet laser to form ions by irradiating the sample directly, without using any matrices, for ion formation through interaction with the electrospray plume. (wikipedia.org)
  • Implementation of TRMS builds on the ability of mass spectrometers to process ions within sub-second duty cycles. (wikipedia.org)
  • spectra
  • After preliminary analysis by positive and negative modes, samples and mixtures of standards were derivatized by methylation to minimize ionization sites and reanalyzed.Positive ionization was less effective and produced more complex spectra than negative ionization. (usgs.gov)
  • Since the weight average molecular weight decreased, it is likely that aggregate formation in the fulvic acid was present prior to derivatization, rather than multiple charging in the mass spectra. (usgs.gov)
  • ambient
  • Performing ionization in an ambient environment, this technique requires little sample preparation and no additional matrix, and can be performed on natural, uneven surfaces. (springer.com)
  • analysis
  • The analysis of single cells and subcellular components by conventional methods of mass spectrometry may be problematic. (google.com)
  • This early work has led him to be considered an internationally recognized expert in mass spectrometry and separation techniques, and his research has led to advancements in instrumentation for the medical and environmental analysis fields, as well as biological research. (wikipedia.org)
  • This pioneer interface for LC-MS had the same analysis capabilities of GC-MS and was limited to rather volatile analytes and non-polar compounds with low molecular mass (below 400 Da). (wikipedia.org)
  • distributions
  • Effects of methylation, molar response, multiple charging, solvents, and positive and negative ionization on molecular weight distributions of aquatic fulvic acid were investigated by electrospray ionization/mass spectrometry. (usgs.gov)
  • A water cooled Peltier thermoelectric plate is used to control the sample temperature (−10 °C to 80 °C). The IR-MALDESI source is currently used to investigate the fundamentals of the ionization process, in addition to being routinely employed for visualizing analyte distributions in biological, forensic, and pharmaceutical samples. (wikipedia.org)
  • spectrometer
  • Addition of primary alkanols to ε186-θ in 0.1 M ammonium acetate (pH 8), led to dissociation of the complex, as observed in the mass spectrometer. (edu.au)
  • In-source collision-induced dissociation experiments and other results suggested that the ε186-θ complex dissociated in the mass spectrometer, and that the stability (with respect to dissociation) of the complex in vacuo was dependent on the solution from which it was sampled. (edu.au)
  • A versatile IR-MALDESI MSI source was designed and implemented, which is currently coupled to a high resolving power hybrid Quadrupole-Orbitrap mass spectrometer. (wikipedia.org)
  • liquid
  • In early versions of thermospray, an infrared laser was directed at a liquid spray tip to heat the sample and aid in ionization. (wikipedia.org)
  • The name electrospray is used for an apparatus that employs electricity to disperse a liquid or for the fine aerosol resulting from this process. (wikipedia.org)
  • This effect is clearly related to electrosprays, even though Gilbert did not record any observation related to liquid dispersion under the effect of the electric field. (wikipedia.org)
  • organic
  • Zare used two-step laser mass spectrometry (L2MS), a technique that is particularly sensitive to organic molecules, to examine samples from the interior of the meteorite. (wikipedia.org)
  • 1990s
  • By the end of the 1990s, Smith's achievements included the electrodynamic ion funnel and a micro-dialysis device for the rapid purification of samples analyzed using mass spectrometry. (wikipedia.org)
  • In the late 1990s, Smith's group was also extensively involved in the development and application of Fourier transform ion cyclotron resonance (FTICR) mass spectrometry, which provided the basis for much greater MS resolution and mass measurement accuracy, and particularly in the development of these technologies for applications in proteomics. (wikipedia.org)
  • deconvolution
  • The abundance of ten fatty acyl chains at 46 TAG masses (mass-to-charge ratio, m/z) were determined after isotopic deconvolution and correction by adjustment factors at each TAG mass. (osti.gov)