• Spectrom
  • Publications] R.Arakawa, S.Uemura, T.Ichihara, I.Katakuse: 'A Handy Ionized Spray Source Using a Cosmetic Ionizer for ESI Mass Spectrometry'J.Mas Spectrom.Soc.Jpn. (nii.ac.jp)
  • spectroscopy
  • J. F. J. Todd, "Recommendations for nomenclature and symbolism for mass spectroscopy," Pure and Applied Chemistry , vol. 63, pp. 1541-1566, 1991. (hindawi.com)
  • Lipidomics is a relatively recent research field that has been driven by rapid advances in technologies such as mass spectrometry (MS), nuclear magnetic resonance (NMR) spectroscopy, fluorescence spectroscopy, dual polarisation interferometry and computational methods, coupled with the recognition of the role of lipids in many metabolic diseases such as obesity, atherosclerosis, stroke, hypertension and diabetes. (wikipedia.org)
  • In modern times, H-D exchange has primarily been monitored by the methods: NMR spectroscopy, mass spectrometry and neutron crystallography. (wikipedia.org)
  • spectra
  • After preliminary analysis by positive and negative modes, samples and mixtures of standards were derivatized by methylation to minimize ionization sites and reanalyzed.Positive ionization was less effective and produced more complex spectra than negative ionization. (usgs.gov)
  • Since the weight average molecular weight decreased, it is likely that aggregate formation in the fulvic acid was present prior to derivatization, rather than multiple charging in the mass spectra. (usgs.gov)
  • spectrometric
  • Here we applied a real-time mass spectrometric technique to investigate differences in volatile metabolic profiles of oral bacteria that cause periodontitis. (uzh.ch)
  • Han and Gross first defined the field of lipidomics through integrating the specific chemical properties inherent in lipid molecular species with a comprehensive mass spectrometric approach. (wikipedia.org)
  • liquid
  • In early versions of thermospray, an infrared laser was directed at a liquid spray tip to heat the sample and aid in ionization. (wikipedia.org)
  • The name electrospray is used for an apparatus that employs electricity to disperse a liquid or for the fine aerosol resulting from this process. (wikipedia.org)
  • This effect is clearly related to electrosprays, even though Gilbert did not record any observation related to liquid dispersion under the effect of the electric field. (wikipedia.org)
  • sensitivity
  • He applied it for increasing the sensitivity of ESI-MS. His group has continued to refine and extend ion funnel technology, which is now widely applied in mass spectrometry and ion mobility instrumentation. (wikipedia.org)
  • high
  • J. R. Chapman, R. T. Gallagher, E. C. Barton, J. M. Curtis, and P. J. Derrick, "Advantages of high-resolution and high-mass range magnetic-sector mass spectrometry for electrospray ionization," Organic Mass Spectrometry , vol. 27, pp. 195-203, 1992. (hindawi.com)
  • A versatile IR-MALDESI MSI source was designed and implemented, which is currently coupled to a high resolving power hybrid Quadrupole-Orbitrap mass spectrometer. (wikipedia.org)
  • To simplify the discussion, the following paragraphs will address the case of a positive electrospray with the high voltage applied to a metallic emitter. (wikipedia.org)
  • technique
  • Zare used two-step laser mass spectrometry (L2MS), a technique that is particularly sensitive to organic molecules, to examine samples from the interior of the meteorite. (wikipedia.org)
  • The IR-MALDESI source can be used for mass spectrometry imaging (MSI), a technique using MS data collected over the sample area to visualize the spatial distribution of specific analyte molecules. (wikipedia.org)
  • 1990s
  • By the end of the 1990s, Smith's achievements included the electrodynamic ion funnel and a micro-dialysis device for the rapid purification of samples analyzed using mass spectrometry. (wikipedia.org)
  • In the late 1990s, Smith's group was also extensively involved in the development and application of Fourier transform ion cyclotron resonance (FTICR) mass spectrometry, which provided the basis for much greater MS resolution and mass measurement accuracy, and particularly in the development of these technologies for applications in proteomics. (wikipedia.org)
  • source
  • The ablated material is captured in an exposed flowing solvent stream that carries the ablated material to the electrospray source. (biomedsearch.com)
  • M. Yamashita and J. B. Fenn, "Electrospray ion source. (hindawi.com)
  • MALDESI was introduced in 2006 as the first hybrid ionization source combining laser ablation and electrospray post-ionization using a resonantly excited matrix (endogenous or exogenous). (wikipedia.org)
  • A water cooled Peltier thermoelectric plate is used to control the sample temperature (−10 °C to 80 °C). The IR-MALDESI source is currently used to investigate the fundamentals of the ionization process, in addition to being routinely employed for visualizing analyte distributions in biological, forensic, and pharmaceutical samples. (wikipedia.org)
  • Using the IR-MALDESI imaging source, a variety of dye classes were analyzed from various fabrics with little to no sample preparation allowing for the identification of the dye mass and in some cases the fiber polymer. (wikipedia.org)
  • deconvolution
  • The abundance of ten fatty acyl chains at 46 TAG masses (mass-to-charge ratio, m/z) were determined after isotopic deconvolution and correction by adjustment factors at each TAG mass. (osti.gov)
  • emitter
  • A classical electrospray setup is considered, with the emitter situated at a distance d {\displaystyle d\,} from a grounded counter-electrode. (wikipedia.org)
  • determination
  • The last article in the thesis reports studies of noncovalent interactions by means of nanoelectrospray ionization mass spectrometry (nanoESI-MS) for determination of the specific binding of selected drug candidates to HSA. (diva-portal.org)
  • While initial studies focused on the elucidation of stoichiometry by means of simple mass determination, developments in MS technology and methodology now allow researchers to address questions of shape, inter-subunit connectivity and protein dynamics. (technologynetworks.com)