Spectrometric spectrometry mass electrospray ionization. Medical search. Frequent questions

Rapid Communications in Mass Spectrometry , 25 (19), 2943-2950. (edu.hk)

Separation of peptides was achieved via liquid chromatography, and mass spectrometric analyses were conducted by electrospray ionization triple-quadrupole mass spectrometry in the multiple reaction monitoring mode. (bvsalud.org)

Straight-forward mass characterization of the complex mixtures could be achieved. (degruyter.com)
The rapid and highly sensitive atmospheric-pressure ionization MS with electrospray ionization analysis technique proposed here is well suited for direct characterization of sucrose esters. (degruyter.com)
Mass spectrometry(MS) methods, particularly with the development of softionization techniques, such as electrospray (ESI) and matrix- assisted laser desorption/ionization (MALDI), have played an important role in the characterization of isolated Roots of aconite were purchased from a drug store. (healthdrugpdf.com)
High-performance liquid chromatography with diode array and electrospray ionization mass spectrometric detection was used to carry out the comprehensive characterization of a lemon verbena extract with demonstrated antioxidant and antiinflammatory activity. (chemfaces.com)
We develop and apply methods based on ion mobility mass spectrometry for the characterization of small molecules and biopolymers. (oregonstate.edu)
Tandem mass spectrometric characterization of thiol peptides modified by the chemoselective cationic sulfhydryl reagent (4-iodobutyl)triphenylphosphonium--effects of a cationic thiol derivatization on peptide fragmentation. (oregonstate.edu)

Once ionized, the volatiles are pulled into the mass spectrometer for analysis (4). (jove.com)
Choose the appropriate vessel for growing your cultures, considering the growth requirements of the species in your experiment (e.g., aeration, light, temperature, etc.), as well as the efficient delivery of volatiles to the mass spectrometer. (jove.com)
Peptide masses of the peaks were determined with a MALDI-TOF mass spectrometer. (bvsalud.org)
All experiments were performed using an LCQ ion trap All aconitines share a common C19-norditerpenoid skele- mass spectrometer (ThertmoFinnigan, San Jose, CA, USA) ton. (healthdrugpdf.com)
Discovery Proteomics and Absolute Protein Quantification Can Be Performed Simultaneously on an Orbitrap-Based Mass Spectrometer. (ncsu.edu)
The UV-visible spectrophotometry was used to delimit the class of phenolic compound and the accurate mass measurements on time-of-flight spectrometer enabled to identify the compounds present in the extract. (chemfaces.com)
An API 4000 [tandem mass spectrometer (AB SCIEX)] combined with a CTC Pal autosampler (CTC Analytics AG) and a Shimadzu ultra-fast liquid chromatography (UFLC) system were applied for the direct liquid chromatography-tandem mass spectrometric assay analysis using electrospray ionization in positive ion mode. (nih.gov)
Extracts of plant material or of dyed silk or wool were analyzed by HPLC with photodiode array and mass spectrometric detection using an Agilent 1100 high performance liquid chromatography system consisting of an automatic injector, a gradient pump, a Hewlett-Packard series 1100 photodiode array detector, and an Agilent series 1100 VL on-line atmospheric pressure ionization electrospray ionization mass spectrometer. (mfa.org)
Collaborate with the mass spectrometer manufacturers regarding the atmospheric interface development and system integration aspects of the project. (findapostdoc.com)
To obtain structural information, common types of mass spectrometers are used, such as the triple quadrupole mass spectrometer (QqQ) and the (linear) ion trap mass spectrometer (ITMS) [5]. (betasciencepress-publishing.com)

The proanthocyanidins in three foods (pinto beans, plums and cinnamon) were studied with electrospray ionization (ESI) mass spectrometry (MS) in the negative mode following separation by normal-phase high-performance liquid chromatography. (marscocoascience.com)
A high-performance liquid chromatography-tandem mass spectrometric (HPLC-MS-MS) method is presented and evaluated for the determination of S-benzylmercapturic acid (S-BMA) and S-phenylmercapturic acid (S-PMA) in human urine. (cdc.gov)
High-performance liquid chromatography with diode array detection coupled to electrospray time-of-flight and ion-trap tandem mass spectrometry to identify phenolic compounds from a lemon verbena extract. (chemfaces.com)
Zhang Y, Wang Q, Zhang G, Jia W, Ren Y, Wu Y. Biomarker analysis of hemoglobin adducts of acrylamide and glycidamide enantiomers for mid-term internal exposure assessment by isotope dilution ultra-high-performance liquid chromatography tandem mass spectrometry. (cdc.gov)
A sensitive and accurate high performance liquid chromatography-mass spectrometric (HPLC-MS) method for the intracellular determination of 14 antiretroviral drugs in peripheral blood mononuclear cells (PBMCs) for HIV+ patients was validated. (unito.it)

The detection was carried out in multiple reaction monitoring (MRM) mode via negative electrospray ionization (ESI) interface. (unboundmedicine.com)

Liquid chromatographic/electrospray ionization mass spectrometric studies of proanthocyanidins in foods. (marscocoascience.com)
To investigate the pharmacokinetics of arotinoid acid, a sensitive and selective liquid chromatographic-tandem mass spectrometric method (LC-MS/MS) for the determination of arotinoid acid in human plasma was developed and validated. (unboundmedicine.com)
The chromatographic analysis consists of a reversed-phase gradient system, which uses electrospray ionization in negative-ion mode with a triple-quadrupole mass spectrometric detector. (cdc.gov)
With the help of a combined mix of typical chromatographic methods, one sesquiterpenoid viglutin (1), one alkaloid viglutoside (2), one -pyranone viglutanone (3), along with two salts sodium phaseate (4) and sodium p-coumarate (5), had been characterized and their buildings were made of the nuclear magnetic resonance (NMR) spectral elucidation and mass (MS) spectrometric evaluation. (engineering-gdfsuez.com)
For accurate quantitative or qualitative analysis, mass spectrometry is today combined with different chromatographic techniques. (lu.se)
Chromatographic separations were performed using a gradient program with a mixture of water (0.05% formic acid), as mobile phase A and acetonitrile (0.05% formic acid), as mobile phase B. Analytes quantification was performed by electro-spray ionisation-single quadrupole mass spectrometry using the selected ion recording (SIR) detection mode. (unito.it)

An LC-MS/MS SCIEX API4000 instrument, furnished with a positive electrospray ionization source and HPLC of Shimadzu, consisted of an SIL-HTC autosampler, dual pump, and column oven, which were utilized in the present work. (japsonline.com)
HPLC-ESI MS instrumentation enables front-end separation of individual small molecular weight polyphenolic compounds and back end UV-Visible (Photo Diode Array) and mass spectrometric (single quadrupole) detection. (phyto-sol.com)
Two different MS techniques have been coupled to HPLC: on one hand, time-of-flight mass spectrometry, and on the other hand, tandem mass spectrometry on an ion-trap. (chemfaces.com)
The main disadvantage of flight mass spectrometry (MALDI-TOF-MS) or by high- the mouse bioassay is that it requires euthanizing many ani- performance liquid chromatography (HPLC)-electrospray mals. (cdc.gov)
It also requires several days to determine the toxin ionization-tandem mass spectrometry (HPLC- level and type (4-6). (cdc.gov)

Journal of Mass Spectrometry, just accepted. (bham.ac.uk)
International Journal of Mass Spectrometry, in press. (bham.ac.uk)
International Journal of Mass Spectrometry, 43-50. (bham.ac.uk)
International Journal of Mass Spectrometry, 63-70. (bham.ac.uk)

Nano-flow liquid chromatography tandem mass spectrometry (nano-flow LC-MS/MS) is the mainstay in proteome research because of its excellent sensitivity but often comes at the expense of robustness. (nature.com)
In this study, covalent modifications on radical-scavenging peptides prepared from soy protein hydrolysate by MDA and HNE were characterized by liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS/MS). MS/MS analyses detected the formation of Schiff base type adducts of MDA on the side-chain groups of lysine, histidine, arginine, glutamine, and asparagine residues as well as the N-termini of peptides. (uky.edu)
Raster-Mode Continuous-Flow Liquid Microjunction Mass Spectrometry Imaging of Proteins in Thin Tissue Sections. (bham.ac.uk)
Liquid Extraction Surface Analysis for Native Mass Spectrometry: Protein Complexes and Ligand Binding. (bham.ac.uk)
Liquid extraction surface analysis field asymmetric waveform ion mobility spectrometry mass spectrometry for the analysis of dried blood spots. (bham.ac.uk)
Liquid extraction surface analysis mass spectrometry coupled with field asymmetric waveform ion mobility spectrometry for analysis of intact proteins from biological substrates. (bham.ac.uk)
Native Liquid Extraction Surface Analysis Mass Spectrometry: Analysis of Noncovalent Protein Complexes Directly from Dried Substrates. (bham.ac.uk)
TY - JOUR T1 - Determination of arotinoid acid in human plasma by liquid chromatography-tandem mass spectrometry. (unboundmedicine.com)
A specific liquid chromatography-mass spectrometry/mass spectrometry spectrometric procedure for the quantitation of amprenavir drug in biological matrices was developed and validated. (japsonline.com)
The literature on amprenavir unveiled that there are few analytical procedures available for the estimation of drug in API and dosage forms on liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) with more retention times. (japsonline.com)
Mass spectrometry for small molecules includes an overview of mass spectrometric techniques that can be used for analysis of low molecular weight analytes in both the gas and liquid phase. (lu.se)
Gas chromatography in combination with chemical ionization and electron ionization and liquid chromatography in combination with electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photo ionization will be covered. (lu.se)
The aim of this study was the evaluation of the first commercially available in-vitro diagnostic (IVD)- mass spectrometric immunosuppressant assay from Chromsystems (MassTox Immunosuppressants ONEMINUTE Test) and the comparison to a routinely used online solid phase extraction liquid chromatography-tandem mass spectrometric assay method for the measurement of cyclosporine A, everolimus, sirolimus, and tacrolimus in patient whole blood samples. (nih.gov)
Samples were analyzed by using a sensitive and reliable method based on ultra-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry (UPLC/Q-TOF-MS/MS) in both positive and negative ion mode. (westminster.ac.uk)
Mass Spectrometry with Benzyl Esters 1 and 2 To further characterize the conversation between rhodesain and the two benzyl ester-based inhibitors 1 and 2, we performed a liquid-chromatographyCmass spectrometric (LCCMS) analysis of rhodesain that had been incubated with the compounds. (ibs-italy.info)
Liquid chromatography mass spectrometry (LC/MS) techniques are often used to analyze compounds that are non-volatile and thermally unstable. (betasciencepress-publishing.com)
Electrospray ionization (ESI) can continuously evaporate liquid solvent and has become an important technique for use as an interface for LC/MS techniques. (betasciencepress-publishing.com)

The product peptides derived from the endopeptidase injection containing a sample with more than a minimum activities of BoNTs are detected by matrix-assisted laser- lethal dose show symptoms of botulinum intoxication and desorption ionization time-of-flight mass spectrometry. (cdc.gov)

120,000 peptides in 16 h and sample multiplexing using tandem mass tags increases throughput to 11 proteomes in 16 h. (nature.com)
METHODS: A mass spectrometric method was generated for the measurement of tryptic peptides in urine sediment. (bvsalud.org)
Mice receiving the appropriate anti-BoNT serotype anti- a unique cleavage site on a unique peptide, the mass-spe- body are asymptomatic and survive, while mice treated cific product peptides detected by mass spectrometry dif- with the other serotype antibodies show symptoms of botu- ferentiate active BoNT serotypes. (cdc.gov)
The absolute amount of toxin detected in the then serotype-specific product peptides are detected by mouse bioassay is not well defined but is thought to be either matrix-assisted laser-desorption ionization time-of- 10-20 pg/mL for BoNT A (7,8). (cdc.gov)

The fact that trace concentrations of gases in contact with an electrospray plume were efficiently ionized was first observed by Fenn and colleagues when they noted that tiny concentrations of plasticizers produced intense peaks in their mass spectra. (wikipedia.org)
As charging ions originate from nano-droplets, and no high energy ions are involved at any point of the ionization process nor the creation of ionizing agents, fragmentation in SESI is remarkably low, and the resulting spectra are very clean. (wikipedia.org)
The spectra are collected in positive ion mode using 0.1 % formic acid, 5.0% methanol, and 94.9 % water (v/v) as the electrospray solution, delivered at 5 nL/s through a non-conductive silica capillary with a sharpened needle tip (40 μm ID). (jove.com)
Spectra are recorded using the following ionisation techniques: matrix assisted laser desorption and ionisation (MALDI), electro spray ionisation (ESI) and Electron Impact (EI). (sdu.dk)
If you (and your supervisor) are in doubt concerning how a given substance should be analysed, or if you have any questions concerning recorded spectra, you are welcome to contact the staff in the mass spectrometry lab. (sdu.dk)
The chemical structures of the DNA adducts were confirmed by accurate mass values, collision-induced fragmentation tandem mass spectra as well as isotopic patterns. (edu.hk)
Interpretation of mass spectra and data treatment will also be covered, together with practical aspects of mass spectrometry method development. (lu.se)
For example, protonated, ammonium, and alkali adducts are generally observed in the mass spectra for positively charged molecules, while deprotonated molecules are observed for negatively charged compounds [4]. (betasciencepress-publishing.com)

Comprehensive mapping of O-glycosylation in flagellin from Campylobacter jejuni 11168: A multi-enzyme differential ion mobility mass spectrometry approach. (bham.ac.uk)
We use ion mobility mass spectrometry as orthogonal method for the analysis of small molecules in complex matrices and biological systems. (oregonstate.edu)

Samples are typically analyzed by gas chromatography mass spectrometry which results in a complicated chromatogram that must be interpreted. (nist.gov)

Secondary electrospray ionization mass spectrometry (SESI-MS) enables the detection of volatile organic compounds (VOCs) without the need for any sample pretreatment. (jove.com)
Through this project a number of ambient ionization mass spectrometry approaches have been developed that allow for temperature gradients capable of unlocking detection across this range, including infrared thermal desorption (IRTD)-DART-MS and Joule heating thermal desorption (JHTD-DART-MS). These platforms have been shown to readily analyze the range of explosive compounds as well as black powder, black powder substitutes, and smokeless powders. (nist.gov)
A novel method for the detection of synthetically useful pentacarbonyl chromium and tungsten carbene complexes by electrospray ionization Fourier transform ion cyclotron resonance (ESI-FTICR) mass spectrometry is presented which utilizes the addition of CN- anions to the electrophilic carbene carbon. (fu-berlin.de)
In this publication we report on the development of a quantitative enzymatic method for the detection of four botulinum neurotoxin (BoNT) serotypes responsible for human botulism by MALDI-TOF mass spectrometry. (cdc.gov)
Mixtures of neutralizing anti- detection of the unique peptide products by mass spec- bodies are given to mice in conjunction with the sample. (cdc.gov)

Secondary electro-spray ionization (SESI) is an ambient ionization technique for the analysis of trace concentrations of vapors, where a nano-electrospray produces charging agents that collide with the analyte molecules directly in gas-phase. (wikipedia.org)

In the present study, electrospray ionization coupled with ion trap mass spectrometry (ITMS), triple quadrupole MS or quadrupole time-of-flight MS was applied for the analysis of DNA adducts formed by BBQs. (edu.hk)

Presented at the American Society for Mass Spectrometry Meeting, Atlanta, GA. Williams, T. I. (2018). (ncsu.edu)

At present, mass spectrometric analysis of lipid extracts, mainly by infusion electrospray ionization, is utilized to determine sensitive and quantitative information of specific SLs in biological processes. (encyclopedia.pub)
Lipid entities revealed by mass spectrometry and associated with development of therapy resistance can thus support molecular diagnosis and provide a potential complementary cancer biomarker. (unica.it)

Mass spectrometry (MS) requires the conversion of analytes into detectable gas-phase ions that are manipulated by electric fields for mass to charge (m/z) analysis, and the most widely used ionization technique for biological compounds is electrospray ionization (ESI). (uky.edu)
This course covers modern mass spectrometry with a particular focus on the analysis of low molecular weight analytes. (lu.se)
The chemical structures of metabolites were elucidated by comparing the retention time, accurate molecular mass, and fragmentation patterns of analytes with those of PPD. (westminster.ac.uk)

The envisioned instrument will have atmospheric pressure/ambient imaging module using desorption electrospray ionization (DESI), AP-laser desorption ionization (AP-LDI) and combination thereof. (findapostdoc.com)

The mass spectrometric behaviour of the HIF stabilizer drug candidate BAY 85-3934 and a glucuronidated metabolite (BAY-348) were characterized by electrospray ionization-(tandem) mass spectrometry (ESI-MS(/MS)) and multiple-stage mass spectrometry (MSn). (aktsignals.com)
Fragmentation pathways of aconitine-type alkaloids were investigated by electrospray ionization/ion trap multistage tandem mass spectrometry. (healthdrugpdf.com)
adduct formation, chemical strategies and tandem mass spectrometry for their detectioan and identification. (oregonstate.edu)
In the mouse bioassay, when the injected matography-tandem mass spectrometry method for quan- dose is high, mice typically develop signs of botulism with- tifying active toxin, where the amount of toxin can be in 8 hours. (cdc.gov)

However, as this problem is solved, and new instruments are able to handle larger and more specific molecules, the ability to perform on-line, real time analysis of molecules naturally released in the air, even at minute concentrations, is attracting attention to this ionization technique. (wikipedia.org)
The results indicate the atmospheric-pressure ionization MS with electrospray ionization analysis is an effective method for the analysis of sucrose esters composed of different isomers. (degruyter.com)
SESI ionization occurs by proton transfer reactions between the electrospray solution and the volatile analyte, and is therefore suitable for the analysis of hetero-organic molecules, just as in traditional electrospray ionization (ESI). (jove.com)
Ambient ionization mass spectrometry for in situ analysis of intact proteins. (bham.ac.uk)
Top-Down LESA Mass Spectrometry Protein Analysis of Gram-Positive and Gram-Negative Bacteria. (bham.ac.uk)
You hand in samples for mass spectrometric analysis in room Ø9-509-1 , enclosed by a duly filled in MS requisition. (sdu.dk)
The key aim of this project was to develop the concept of electrospray-friendly ligands as a new ionisation method for the analysis of neutral metal complexes by electrospray mass spectrometry (ESMS). (waikato.ac.nz)
Mass spectrometry and in silico sequence analysis were used to identify phosphate sites on the BPV E1 protein and kinases that may recognize these sites. (biomedcentral.com)
Mass spectrometric analysis identified seven phosphorylated amino acids on the BPV E1 protein. (biomedcentral.com)
Mass spectrometry is the favored analytical technology for SL analysis. (encyclopedia.pub)
In this dissertation, the supramolecular interactions of a variety of model lignin monomers and dimers are fundamentally characterized to improve mass spectrometric analysis and potential applications of lignin as a renewable source of valuable phenolics. (uky.edu)
The primary challenge facing ESI-MS analysis of lignin is ionization because lignin compounds do not readily accept protons for positive mode analysis and negative mode analysis causes destabilization and in-source fragmentation. (uky.edu)
aconitines,2±4 the quantitative analysis and the stereo- Authentic samples of aconitine (AC), hypaconitine (HC) chemistry of aconitines,5±7 and the direct analysis of and mesaconitine (MA) were purchased from China Drug aconitine mixtures. (healthdrugpdf.com)
Course organizer Peter Spégel Center for Analysis and Synthesis Department of Chemistry Lund University course gives theoretical and practical knowledge on how mass spectrometry can be used in qualitative and quantitative analyses of small molecules. (lu.se)
Practical parts include analysis of own or supplied samples by chromatography and mass spectrometry, with subsequent data analysis and identification of sample components. (lu.se)
5. Mass spectrometry-enabled protein conformational and interaction analysis with emphasis on H/D exchange mass spectrometry. (oregonstate.edu)
The actual work includes the construction of laser source, modalities for post-desorption ionisation and collecting the ions at atmospheric pressure for mass analysis. (findapostdoc.com)

High Field Asymmetric Waveform Ion Mobility Spectrometry in Nontargeted Bottom-up Proteomics of Dried Blood Spots. (bham.ac.uk)
We use a combination of biochemical methods, analytical chemistry and mass-spectrometry-based proteomics to understand dysregulation in disease and environmental exposure. (oregonstate.edu)

OBJECTIVE: To create an efficient and robust mass spectrometric method for the simultaneous quantitation of podocin and podocalyxin in urine samples and to evaluate urinary podocin and podocalyxin levels in patients with nephrotic syndrome (NS). (bvsalud.org)
An isotope dilution mass spectrometry based method (LC-MS/MS triple quadrupole MS using electrospray ionization) was used for routine quantitation of AFB-lys as a measure of individual exposure to aflatoxin B1. (cdc.gov)

Collision energies for the MSn analyses ranged from variations lie in the substituents on the C3, C10 and N atoms 25±42% of maximum, depending on the mass of the (Table 1). (healthdrugpdf.com)

This method is nondestructive, provided the ionization proceeds under soft conditions. (fu-berlin.de)
CONCLUSIONS: This proposed mass spectrometric method provides technological evidence that will benefit the clinical field in the early diagnosis and follow-up of NS. (bvsalud.org)
The separative method was coupled to MS with post-column lithium adduct ionization to identify lignin dimers. (uky.edu)
We develop and apply biomolecular mass spectrometry method for detecting and identifying metabolites and xenobiotics in complex biological matrices. (oregonstate.edu)
Current methods for detecting BoNT include a mouse cause human botulism (A, B, E, and F). We developed a bioassay (2-4) and an enzyme-linked immunosorbent assay rapid, mass spectrometry-based method (Endopep-MS) to (ELISA) (5,6). (cdc.gov)

In addition to the primary desorption ionization methods, the ion source will feature low-temperature plasma and excimer lamp post-ionization capabilities. (findapostdoc.com)

Electron capture dissociation mass spectrometry of phosphopeptides: Arginine and phosphoserine. (bham.ac.uk)
Probing the Electron Capture Dissociation Mass Spectrometry of Phosphopeptides with Traveling Wave Ion Mobility Spectrometry and Molecular Dynamics Simulations. (bham.ac.uk)

The electrospray ionisation mass spectrometric behaviour of various complexes of beryllium have been investigated in this thesis. (waikato.ac.nz)

In this regime, nanodroplets from the electrospray evaporate very quickly to form ion clusters in equilibrium. (wikipedia.org)

Here we were curious whether quantitative differences in phospholipid composition between cisplatin resistant and sensitive model cancer cell lines could be revealed by mass spectrometry means. (unica.it)

Commercial and synthesized sucrose fatty acid esters were qualitatively analyzed by atmospheric-pressure ionization MS with electrospray ionization. (degruyter.com)
Here, we examine how additives to an atmospheric-pressure solution-cathode glow discharge (SCGD) influence molecular ionization and fragmentation. (aip.org)

Native mass spectrometry imaging of intact proteins and protein complexes in thin tissue sections. (bham.ac.uk)
Direct Tissue Profiling of Protein Complexes: Toward Native Mass Spectrometry Imaging. (bham.ac.uk)

Recently, solution-electrode glow discharges (SEGDs) have shown great utility as ionization sources for mass spectrometry (MS). The solution composition of SEGD electrodes is pivotal to their performance as it influences analyte-ion formation. (aip.org)
The changing composition of the SCGD solution alters analytical performance, but also provides insight into analyte ionization and fragmentation processes. (aip.org)

The monomer and dimer structures of the amyloid fragment Aβ(1-16) sequence formed in H 2 O were investigated using electrospray ionization mass spectrometry (MS) and tandem MS (MS/MS). Aβ16 monomers and dimers were indicated by signals representing multiple proton adduct forms, [monomer+zH] n+ (=M z+ , z = charge state) and [dimer+zH] z+ (=D z+ ), in the MS spectrum. (accesson.kr)

The ions under study have been mass-selected and subjected to collision-induced decay (CID) experiments in order to examine their fragmentation reactions. (fu-berlin.de)
Traditionally, aconitines in crude aconite can be divided equipped with an electrospray source and capable of into two main types according to the substituent at position 8 analyzing ions up to m/z 2000. (healthdrugpdf.com)
In addition, the ability to produce multiple charged molecular ions makes it possible to observe very large molecules (e.g., a large variety of polymers, proteins, and DNA fragments) using an instrument with a relatively small mass range. (betasciencepress-publishing.com)
Furthermore, molecular ionization processes can result in positively and negatively charged ions. (betasciencepress-publishing.com)

METHODS The phospholipid content of cell membranes of cancer cell lines CCRF-CEM and A2780, both responsive and resistant to cisplatin, was analysed by solid phase extraction (SPE) and electrospray ionization mass spectrometry (ESI-MS and tandem MS-MS). Extracts were obtained by disruption of cells with a dounce tissue grinder set followed by centrifugation. (unica.it)

Different types of mass analysers will also be discussed, including the quadrupole, the 3d and linear ion traps, the time of flight, the orbitrap and the Fourier transform ion cyclotron resonance mass analysers, and their combinations. (lu.se)

SESI works in combination with mass spectrometry or ion-mobility spectrometry. (wikipedia.org)
In the early days of SESI, two ionization mechanisms were under debate. (wikipedia.org)
SESI, combined with High Resolution Mass Spectrometry, provides time-resolved, biologically relevant information of living systems, where the system does not need to be interfered with. (wikipedia.org)
As the volatiles traverse the SESI reaction chamber they pass through the electrospray cloud and become ionized (3). (jove.com)
Inset: The SESI electrospray needle is a silica capillary (40 μm ID) with a sharpened needle tip. (jove.com)
The SESI reaction chamber was custom built and fitted to an API-3000 (SCIEX), replacing the original electrospray ion source. (jove.com)

Here, we have used electrospray ionisation mass spectrometry (ESI-MS) to determine the patterns of alteration to individual molecular species compositions of PC, PE and phosphatidylinositol (PI) in response to gradually decreasing temperature. (silverchair.com)

We have utilized mass spectrometry of purified bovine papillomavirus E1 protein to identify and characterize new sites of phosphorylation. (biomedcentral.com)
We study protein mobility and interactions by solution-phase hydrogen/deuterium exchange mass spectrometry (HDX-MS). (oregonstate.edu)

Various mass spectrometry techniques employing electrospray ionization and chip nanospray were employed to study the interaction of oxaliplatin with carnosine as well as two of its derivatives being β-alanyl-N-methylhistidine (anserine) and N-Acetylcarnosine (NAC). (lboro.ac.uk)

The emphasis is on understanding the fundamental processes involved, the instrumentation used, including different ionization sources and mass analyzers, and interpretation of generated data. (lu.se)
The Biological Mass Spectrometry Theme focuses on the development of new instrumentation for mass spectrometric imaging (MSI) allowing the visualisation of molecular distributions at subcellular level and the de-novo structure elucidation of chemical species detected by MSI techniques. (findapostdoc.com)

Some related techniques are laser ablation electrospray ionization, proton-transfer-reaction mass spectrometry and selected-ion flow-tube mass spectrometry. (wikipedia.org)

We focus on mass spectrometry to study biomolecules, their interactions and dynamics in relation to their biological functions. (oregonstate.edu)
For this purpose we combine chemistry, separation technologies and mass spectrometry to detect, identify and quantify biomolecules in biological systems. (oregonstate.edu)
The post reports to the Franklin's Theme Lead for Biological Mass Spectrometry, Professor Zoltan Takats and will also work with MS leads of the Franklin's Member Institutions. (findapostdoc.com)

Accurate mass is not necessary for positive identification of compounds in general. (sdu.dk)
Interestingly, for both investigated compounds we found that rhodesain catalyzed the hydrolysis of the benzyl ester of the dipeptide acknowledgement unit to the corresponding acid, indicated by a mass shift of 90 Da corresponding to the loss of the terminal benzyl group (Physique 5). (ibs-italy.info)

While SEGDs produce Taylor cones similar to electrospray ionization, the influence of solution-electrode composition on molecular-ion formation has not been studied. (aip.org)

Organisms7

Diseases1

Chemicals and Drugs88

Analytical, Diagnostic and Therapeutic Techniques and Equipment51

Phenomena and Processes42

Disciplines and Occupations8

Anthropology, Education, Sociology and Social Phenomena4

Technology, Industry, Agriculture1

Information Science5

Health Care8

Rapid Communicatio1

Triple-quadrupole mass spectrometry1

Characterization6

Spectrometer10

High Performance Li5

Negative electrospray ionization1

Chromatographic6

HPLC5

Journal of Mass Spec4

Liquid17

Time-of-Flight Ma1

Peptides4

Spectra8

Mobility mass spectrometry2

Chromatography mass spectrometry1

Detection5

Electro-spray1

Quadrupole time-of-fli1

20181

Lipid2

Analytes3

Laser desorption1

Tandem mass4

Analysis17

Proteomics2

Quantitation2

Analyses1

Method5

Desorption ionization1

Phosphopeptides2

Behaviour1

Evaporate1

Quantitative1

Atmospheric-pressure2

Complexes2

Analyte2

Monomers and dimers1

Ions4

Solid phase extr1

Fourier1

SESI6

Patterns1

Protein2

Derivatives1

Instrumentation2

Techniques1

Biological3

Compounds2

Molecular1