Gene Knockdown TechniquesRNA InterferenceRNA, Small InterferingSensitivity and SpecificityZebrafishSubstrate SpecificityLentivirusZebrafish ProteinsMorpholinosCell Line, TumorGene SilencingEmbryo, NonmammalianMolecular Sequence DataGenetic VectorsOligonucleotides, AntisenseCell LineAnimals, Genetically ModifiedBase SequenceGreen Fluorescent ProteinsSignal TransductionTransfectionDoxycyclineGene Expression Regulation, DevelopmentalGenetic TechniquesCell ProliferationRNA, MessengerGene Expression RegulationCells, CulturedReverse Transcriptase Polymerase Chain ReactionGene TargetingRNA, Double-StrandedAntibody SpecificityApoptosisHeLa CellsBlotting, WesternDown-RegulationMutationCell MovementPromoter Regions, GeneticAmino Acid SequenceTranscription FactorsGene ExpressionTransgenesPhenotypeCell DifferentiationLarvaPhosphorylationCell SurvivalModels, BiologicalSpecies SpecificityProtein BindingMice, Inbred C57BLMice, KnockoutProtein-Serine-Threonine KinasesFlow CytometryMice, TransgenicTime FactorsBinding SitesNeuronsDisease Models, AnimalHEK293 CellsKineticsProtein Structure, TertiaryModels, MolecularSequence Homology, Amino AcidOrgan SpecificityGene Expression Regulation, NeoplasticReproducibility of ResultsRecombinant Proteins