• mutans
  • S. mutans and other anaerobes are the initial colonisers of the tooth surface, and play a major role in the establishment of the early biofilm community. (wikipedia.org)
  • strain PK1910 (Va) in one- and two-species cultures with S. mutans (Sm) in BHI (no lactate) or BHI plus 1% lactate (+lactate). (asmscience.org)
  • diseases
  • In 2011, researchers discovered that Fusobacterium flourishes in colon cancer cells, and is often also associated with ulcerative colitis, although researchers have not determined if the organism actually causes these diseases or if it simply flourishes in the environment these diseases create. (wikipedia.org)
  • Oral diseases develop due to an imbalance between microbial colonization and the host. (pubmedcentralcanada.ca)
  • Bacteria then attach to the pellicle layer, form micro-colonies, and mature on the tooth, which can result in oral diseases. (wikipedia.org)
  • Ecological theories of oral infectious diseases such as Marsh's ecological plaque hypothesis [ 3 ] and the recent polymicrobial synergy and dysbiosis model of disease development [ 4 ] emphasize the role of complex community changes as drivers of disease. (springer.com)
  • However, despite substantial research into cause of these infectious oral diseases, relatively little progress has been made in understanding how community dynamics and species interactions drive disease. (springer.com)
  • Differences in immunological and physiological responses to stimulation with bacterial structures such as LPS, single bacterial species, and multiple bacterial species in vitro and in vivo have demonstrated that it is necessary to study polymicrobial-induced diseases with complex communities to better understand disease etiology. (springer.com)
  • pathogen
  • Although older sources state that Fusobacterium is part of the normal flora of the human oropharynx, the current consensus is that Fusobacterium should always be treated as a pathogen. (wikipedia.org)
  • The red complex, which is recognized as the most important pathogen in adult periodontal disease, represents 8.08% of the 19 bacteria analyzed. (frontiersin.org)
  • Actinobacillus actinomycetemcomitans is considered an oral pathogen due to its virulence factors, its association with localized aggressive periodontitis in young adolescents, and studies indicating that it can cause bone loss. (wikipedia.org)
  • cariogenic
  • After 48 h, C. albicans did not induce differences in total biofilm formation, lactic acid accumulation (cariogenic phenotype) or protease activity (periodontitis phenotype). (pubmedcentralcanada.ca)
  • interactions
  • Future work will continue to be directed towards understanding the molecular mechanisms of bacterial cell-cell interactions and biofilm formation. (ncl.ac.uk)
  • These new research directions made oral microbiologists truly appreciate the fact that the whole is much more than the simple sum of its parts, since the interactions between different components resulted in many new physiological functions which cannot be observed with individual components. (pubmedcentralcanada.ca)
  • surfaces
  • Biofilm formation on artificial surfaces that are placed in the body is particularly problematic since, unlike our own tissues, the artificial surfaces do not contain protective mechanisms to limit microbial colonisation. (ncl.ac.uk)
  • ecological
  • In oral health, the interdental spaces are a real ecological niche for which the body has few or no alternative defenses and where the traditional daily methods for control by disrupting biofilm are not adequate. (frontiersin.org)
  • Of all of the parts of the human body, the interdental (ID) space is a unique place, a real ecological niche, for which the body has few or no alternative defenses and where the traditional daily methods for control by disrupting biofilm are not adequate. (frontiersin.org)
  • Bacteria occupy the ecological niche provided by both the tooth surface and gingival epithelium. (wikipedia.org)
  • hygiene
  • There is professional agreement among dentists that smoking cessation and good oral hygiene are key to effective treatment and positive outcomes for patients. (wikipedia.org)
  • During the experiment individuals used AX mouthwash twice daily in absence of other oral hygiene measures. (frontiersin.org)
  • interdental
  • P. gingivalis was detected in 19% of healthy subjects and represents 0.02% of the interdental biofilm. (frontiersin.org)
  • T. forsythensis and T. denticola (0.02 and 0.04% of the interdental biofilm) were detected in 93 and 49% of healthy subjects, respectively. (frontiersin.org)
  • streptococci
  • Molecular mechanisms of adhesion and colonisation by oral streptococci. (ncl.ac.uk)
  • The acquisition of an ABP by oral streptococci provides an interesting example of adaptive evolution. (springer.com)
  • gingivalis
  • Following breakdown of the host's protective oral tissue barriers, P. gingivalis migrates to developing inflammatory pathologies that associate with Alzheimer's disease (AD). (frontiersin.org)
  • receptors
  • Cell-cell contact is mediated by specific protein adhesins and often, as in the case of inter-species aggregation, by complementary polysaccharide receptors. (wikipedia.org)