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Corynebacterium pseudotuberculosisCorynebacterium InfectionsCorynebacteriumYersinia pseudotuberculosisLymphadenitisYersinia pseudotuberculosis InfectionsSheep DiseasesPhotobacteriumCorynebacterium glutamicumGoat DiseasesGoatsCorynebacterium diphtheriaePhospholipase DMolecular Sequence DataGenome, BacterialHorse DiseasesSheepBacterial ProteinsYersiniaDNA, BacterialYersinia pestisBacterial VaccinesSequence Analysis, DNAHorsesYersinia InfectionsSpecies Specificity
DiphtheriaeCaseous lymphadenitisGenusOvineFacultativeProteinsPseudodiphtheriticumDiphtheriaBacteriumUlceransPasteurellaPathogenicBacteriaLymph nodeBeta-hemolysisYersiniaAntibodiesBacterial speciesUlcerativeRespiratoryIsolatesPathogensInfectionGoatsSheepCorynebacteriaInfectionsClinicalToxigenicStaphylococcusDistinctZoonoticReservoirOrganismTicks are foundIdenticalIsolateLaboratoryOccursHorsesComparativeCasesInvestigationDisease causedResultsVeterinaryStudy
Diphtheriae10
  • C. diphtheriae , C. ulcerans, and rarely, C. pseudotuberculosis produce diphtheria toxin (DT) and thus cause respiratory and cutaneous diphtheria. (cdc.gov)
  • Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
  • The genus contains the species Corynebacterium diphtheriae and the nondiphtherial corynebacteria, collectively referred to as diphtheroids. (medscape.com)
  • In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum . (medscape.com)
  • Three strains of C diphtheriae are recognized, in decreasing order of virulence: gravis, intermedius, and mitis. (medscape.com)
  • Case series from Canada, consistent with global surveillance, have found that the disease burden is increasingly attributed to cutaneous, non-pseudomembranous respiratory and systemic disease from toxigenic and non-toxigenic strains of Corynebacterium diphtheriae and C. ulcerans Footnote 2 Footnote 3 Footnote 4 Footnote 5 Footnote 6 Footnote 7 Footnote 8 . (canada.ca)
  • In addition to disease burden, other toxigenic Corynebacteria ( C. ulcerans or C. pseudotuberculosis ) and non-toxigenic C. diphtheriae may serve to maintain a reservoir for toxigenic respiratory diphtheria Footnote 2 Footnote 4 Footnote 8 . (canada.ca)
  • Corynebacterium diphtheriae is responsible for both endemic and epidemic diphtheria. (who.int)
  • Corynebacterium diphtheriae est responsable à la fois de la diphtérie endémique et épidémique. (who.int)
  • From the nasopharynx of a 5-year-old child it was excreted amicroorganism which is identical to Corynebacterium diphtheriae dose according to morphological and biochemical signs.Microorganism does not produce exotoxin. (eneutron.info)
Caseous lymphadenitis5
Genus4
  • citation needed] Shortly after, it was sampled from abscesses in a sheep by Hugo von Preisz [hu], and the bacterium was named the "Preisz-Nocard" bacillus until further work by German microbiologists in the mid-1900s, when it was recategorized into the Corynebacterium genus. (wikipedia.org)
  • Phylogenetic analyses of the Corynebacterium genus were performed using house-keeping loci but also secreted protein loci from Cp 3/99-5. (gla.ac.uk)
  • This organism is the best known and most widely studied species of the genus. (up.ac.za)
  • Like other members of the genus Vibrio, this species is motile, with a single, polar flagellum. (datapunk.net)
Ovine1
  • A further two Cp strains, an Australian ovine and a North American equine isolate, as well as C. ulcerans NCTC 12077 were sequenced for comparison. (gla.ac.uk)
Facultative1
  • This bacterium is grown at 37 °C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe. (wikipedia.org)
Proteins7
  • 44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
  • Moreover, evidence could be found for probable non-classical export of most of the remaining proteins. (biomedcentral.com)
  • Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
  • In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
  • shows high identity to proteins identified in several P. gingivalis strains [17, 19]. (erksignal.com)
  • Interestingly, we found that HmuY is similar to proteins encoded in several different species belonging to the Bacteroidetes phylum, which consists of three classes: Bacteroidetes, Flavobacteria, and Sphingobacteria [23]. (erksignal.com)
  • Aside from the T3SS, two genes encoding well-characterized virulence proteins are typically found on the PAI, the thermostable direct hemolysin gene (tdh) and/or the tdh-related hemolysin gene (trh). (datapunk.net)
Pseudodiphtheriticum1
Diphtheria1
Bacterium5
  • Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
  • C. pseudotuberculosis is a Gram-positive bacterium that can be either coccoid or filamentous rods, which can be organized into palisades. (wikipedia.org)
  • The present study examined the possibilities that: (i) careful examination of Gram-stained sputum and culture plates may reveal a predominant bacterium such as Corynebacterium spp. (biomedcentral.com)
  • Vibrio parahaemolyticus is a curved, rod-shaped, Gram-negative bacterium found in brackish saltwater, which, when ingested, causes gastrointestinal illness in humans. (datapunk.net)
  • Human granulocytic anaplasmosis ( HGA ) is a tick-borne , infectious disease caused by Anaplasma phagocytophilum , an obligate intracellular bacterium that is typically transmitted to humans by ticks of the Ixodes ricinus species complex, including Ixodes scapularis and Ixodes pacificus in North America. (mdwiki.org)
Ulcerans4
  • Toxigenic Corynebacterium ulcerans was grown from a wound swab sample. (cdc.gov)
  • One of the patient´s 2 dogs was found to harbor a toxigenic C. ulcerans strain. (cdc.gov)
  • Isolation of an undistinguishable toxigenic C. ulcerans strain from an animal and its owner has been documented for 2 dogs ( 2 , 3 ), 2 cats ( 4 , 5 ), and 1 pig ( 6 ) and their respective owners. (cdc.gov)
  • We report the first use of next generation sequencing (NGS) for proving zoonotic transmission of a toxigenic C. ulcerans strain between a pet dog and his human owner. (cdc.gov)
Pasteurella1
  • In general the agents implicated in etiology of respiratory syndrome include a wide spectra of viruses such as PI 3, Adeno and Reo viruses, bacterial species such as Hemophilus, Bordetella, Pasteurella, Corynebacterium, Mycoplasma and Chlamydia along with a chain of predisposing factors mainly the environmental and managemental fluctuations. (cswri.res.in)
Pathogenic1
  • We found pathogenic bacteria in following frequency: 18.7% Staphylococcus aureus , 12.1 % C macginleyi, 10.3% Streptococcus pneumoniae, 8.4% Haemophilus influenzae. (symptoma.com)
Bacteria5
  • C. pseudotuberculosis bacteria tend to localize and form abscesses in the pectoral region and ventral abdomen of the horse. (eliteequineks.com)
  • Ruminants-such as sheep, goats, and cattle-can also become infected with these bacteria, although cross-species transmission is rare and usually only occurs between horses and cattle because they can carry the same strain. (eliteequineks.com)
  • Bayesian analysis of house-keeping loci distinguished the bacteria to a species level. (gla.ac.uk)
  • These bacteria are now known as Corynebacterium ammoniagenes, and are thought to be associated with diaper rash due to their ability to convert urine to ammonia. (microgeninc.com)
  • General Information: They may be found as members of the normal microflora of humans, where these bacteria find a suitable niche in virtually every anatomic site. (up.ac.za)
Lymph node1
  • The first isolation of C. pseudotuberculosis came from a cow lymph node in 1888, by French bacteriologist Edmond Nocard. (wikipedia.org)
Beta-hemolysis1
  • Strains possessing one or both of these hemolysins exhibit beta-hemolysis on blood agar plates. (datapunk.net)
Yersinia2
Antibodies1
  • During 1985-88, in sheep and goats, 7.01% of the animals were found positive for BTV antibodies on AGPT. (cswri.res.in)
Bacterial species2
  • This bacterial species has caused occasional cases of infection in people who work closely with infected small ruminants, resulting in similar swellings of the lymph nodes in the neck and groin. (wikipedia.org)
  • New technologies, such as matrix-assisted laser desorption ionization time of flight (MALDI-TOF) mass spectrometry enable rapid and precise identification of bacterial species [ 6 ], and highly sensitive techniques such as polymerase chain reaction (PCR) can help exclude a role for viruses, mycoplasma, and chlamydia. (biomedcentral.com)
Ulcerative2
  • A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
  • citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
Respiratory1
  • Mycoplasma strains have also been isolated from sheep having respiratory distress and typed as M. agalactiae by using reference sera (National Collection of Type Culture, London). (cswri.res.in)
Isolates1
  • it was found to be more similar to the equine Cp 1/06-A isolate which is the most diverged of the Cp isolates. (gla.ac.uk)
Pathogens1
  • A set of bacterial pathogens have been identified in central nervous infections in livestock and companion animals, although the most of descriptions are restricted to case reports and a lack of comprehensive studies involving CNS-related bacterial infections have been focused on a great number of domestic species. (bvsalud.org)
Infection3
Goats2
  • The management system also found to affect the sero-prevalence of BTD and it was higher in migratory flocks (63.29% in sheep to 84.84% in goats) compared to stationary flocks (35.03% in sheep to 72.88% in goats). (cswri.res.in)
  • Both Y. enterocolitica and Y. pseudotuberculosis are zoonoses (diseases that can be transmitted from animals to humans and vice versa), where the main reservoir is found in animal species such as pigs and cattle, but also goats or dogs. (hygiene-in-practice.de)
Sheep1
  • citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)
Corynebacteria1
  • [ 1 ] More recently, Van den Velde and colleagues have suggested that species of corynebacteria would be more correctly identified based on their cellular fatty acid profiles (ie, for the C14 to C20 fatty acids). (medscape.com)
Infections3
  • Central nervous system (CNS) infections comprise life-threatening clinical conditions in domestic species, and are commonly related to severe sequelae, disability, or high fatality rates. (bvsalud.org)
  • This is why, in case of major outbreaks, human and veterinary medicine must work jointly to examine infections and find the origin of contamination as soon as possible. (hygiene-in-practice.de)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
Clinical3
  • citation needed] It was finally renamed Corynebacterium pseudotuberculosis in 1948, to reflect that the clinical disease signs were similar to disease caused by M. tuberculosis species. (wikipedia.org)
  • In this scenario, we retrospectively investigated selected epidemiological data, clinical findings, bacteriological culture, and in vitro susceptibility patterns of 136 nonrepetitive neurologic cases in domestic species (2005-2021). (bvsalud.org)
  • On the basis of our mutational analysis of HmuY heme ligands [20], an initial step in Rigosertib clinical trial heme transfer could involve disruption of only one of the two axial histidine ligands, as found for Serratia marcescens hemophore HasA [22]. (erksignal.com)
Toxigenic1
Staphylococcus1
  • We describe a patient who developed Corynebacterium striatum native valve endocarditis after receiving two 6-week courses of daptomycin for the treatment of methicillin-resistant Staphylococcus aureus bacteremia and osteomyelitis. (symptoma.com)
Distinct2
  • Botulism is an acute severe neuroparalytic disease caused by bacterial exotoxins produced by distinct strains of Clostridium , mainly Clostridium botulinum . (biomedcentral.com)
  • A distinct correlation seems to exist between presence of tdh, trh, and the two known T3SS variants: observations have shown T3SS2α correlating with tdh+/trh- strains, while T3SS2β correlates with tdh-/trh+ strains. (datapunk.net)
Zoonotic1
  • The existence of multiple prion strains in one animal species and the discovery that these prion strains may have different zoonotic potentials add to the challenges. (infectiousconferences.com)
Reservoir1
  • Although white-tailed deer and other small mammals harbor A. phagocytophilum , evidence suggests that they are not a reservoir for the strains that cause HGA. (mdwiki.org)
Organism1
  • Hot, dry weather is the most common environment where the organism is found, and most pigeon fever cases appear in late summer/early fall (the author first diagnosed a case in August, and her number of cases has increased exponentially since that time). (eliteequineks.com)
Ticks are found1
  • These ticks are found in the US, Europe, and Asia. (mdwiki.org)
Identical1
  • These strains all produce an identical toxin, but the gravis strain is potentially more virulent because it grows faster and depletes the local iron supply, allowing for earlier and greater toxin production. (medscape.com)
Isolate1
Laboratory1
  • From CSWRI, Avikanagar, P. multocida serotype B was isolated from an outbreak of pneumonia and it was compared with a reference strain obtained from FAO regional reference laboratory, Sri Lanka. (cswri.res.in)
Occurs1
  • The species Y. pseudotuberculosis generally occurs only in 0.5 to 1 percent of cases worldwide. (hygiene-in-practice.de)
Horses1
  • As vector patterns change with warming temperatures, C. pseudotuberculosis in horses is re-emerging in the United States. (wikipedia.org)
Comparative2
  • Comparative genomics, both intra- and inter-species showed all the genomes to be highly homologous. (gla.ac.uk)
  • I went with the former, as did Greg, and the other Peter Assessing the Genotypic Differences between Strains of Corynebacterium pseudotuberculosis biovar equi through Comparative Genomics. (btfrocks.com)
Cases3
  • Strain comparison was achieved in these cases by ribotyping alone ( 2 , 3 ), ribotyping in combination with multilocus sequence typing ( 4 , 6 ), or pulsed-field gel electrophoresis analysis ( 5 ). (cdc.gov)
  • Pigeon fever cases used to be found primarily in California, although within the last several years veterinarians have diagnosed cases in many areas of the western United States. (eliteequineks.com)
  • This report present 3 cases of CAP in which Corynebacterium spp. (biomedcentral.com)
Investigation1
  • Defect with dysfunction of antigen-presentation to the immunocompetent cells was found during investigation on the molecule level. (eneutron.info)
Disease caused1
Results2
  • The results presented here compose the most comprehensive coverage of the exoproteome of a corynebacterial species so far. (biomedcentral.com)
  • Due to the limited number of submissions from some species, validation of test results cannot be accomplished within AAVLD requirements. (tamu.edu)
Veterinary1
  • Enter search terms to find related veterinary topics, multimedia and more. (msdvetmanual.com)
Study1