Species infection vesicular stomatitis indiana virus. Medical search. Frequent questions

DMT's main vaccine platform is the recombinant vesicular stomatitis virus (VSV) system. (nih.gov)
Development of recombinant vesicular stomatitis viruses that exploit defects in host defense to augment specific oncolytic activity. (microbe.tv)
A recombinant vesicular stomatitis vaccine vector protected non-human primates in pre- and post-exposure challenge studies. (biomedcentral.com)
Experiments using a recombinant vesicular stomatitis virus expressing the EKV-1 envelope glycoprotein indicate EKV-1 has very broad tropism and can efficiently enter nearly all types of human cells. (wikimili.com)
Experiments using a recombinant vesicular stomatitis virus expressing the EKV-2 envelope glycoprotein indicate EKV-2 has very broad tropism similar to EKV-1. (wikimili.com)

Replication of both viruses is blocked at temperatures above 31°C, suggesting that the viruses are unlikely to infect mammals ( 8 ). (cdc.gov)
No replication of GOLV and HEBV was detected, whereas vesicular stomatitis virus replicated to high concentrations ( Figure 1 ). (cdc.gov)
The tri-segmented virus genome encodes for six (6) multifunctional proteins that engage host factors at a variety of different stages in the replication cycle. (bvsalud.org)
Here we show that mAb RVFV-268 reduces viral replication in rat placenta explant cultures and prevents vertical transmission in a rat model of congenital RVF. (bvsalud.org)
While RVFV is pantropic and infects many cells and tissues, viral replication and necrosis within the liver play a critical role in mediating severe disease. (bvsalud.org)
Replication competent oncolytic viruses (OVs) have recently emerged as a possible option for treatment of high-grade gliomas. (bepress.com)
Upon infection, human adenovirus (HAdV) must block interferon signaling and activate the expression of its early genes to reprogram the cellular environment to support virus replication. (bepress.com)
In eukaryotes, subsequent activation and viral replication is thought to be caused by extracellular stimulation of cellular transcription factors. (lookformedical.com)
We used genetic and biochemical analysis to investigate replication and movement of these viruses and to determine virus-host interactions culminating in disease. (berkeley.edu)
Two viruses with distinct strategies of replication emphasized in these studies. (berkeley.edu)
Three of the common proteins (designated N, P, and L) form the nucleocapsid core, which has an RNA-dependent-RNA-polymerase (RdRp) activity that functions in transcription of mRNAs and replication of the viral genomic and antigenomic RNAs. (berkeley.edu)
We showed that large subnuclear inclusions are formed during SYNV infection of plants and that these inclusions are the sites of viral replication. (berkeley.edu)
Plant and yeast cells were used to characterize this complex by investigating the interactions of the virus and host proteins required for establishment of the subnuclear replication site. (berkeley.edu)
This is a challenging task because the nucleocapsid is the minimal unit of infectivity and must be assembled in cells in order to jumpstart replication. (berkeley.edu)
Besides their function in the virus replication cycle, the viral glycoprotein, nucleoprotein, minor matrix protein and polymerase cofactor are viral determinants of pathogenicity, with evasion of the host innate and adaptive immune responses as the main mechanism. (biomedcentral.com)
Antisense therapies, in which oligonucleotides inhibit viral replication, have shown promising results in non-human primates following post-exposure treatment. (biomedcentral.com)
Sp110 and other NB-associated proteins, induced by type I (α/β) and type II (γ) interferons (IFNs), play a role in IFN response and virus replication [ 8 ]. (biomedcentral.com)
Thus it inhibits replication of parainfluenza virus, feline infectious peritonitis virus (FIPV), vesicular stomatitis virus (VSV), herpes simplex virus (HSV), flock house virus (FHV) etc. (turmericforhealth.com)
Enveloped viruses contain a protective envelope like structure which protects the material required for replication by the virus. (turmericforhealth.com)
Viruses have the advantage of self-replication over molecular tracers. (2bscientific.com)
[9] EKV-1 was present in her blood at 4.5 million RNA copies/mL suggesting robust replication. (wikimili.com)
[10] EKV-1 could not be isolated from the patient's blood sample and live replication-competent virus is not available. (wikimili.com)
[9] EKV-2 was present in her blood at 45,000 RNA copies/mL suggesting modest replication. (wikimili.com)

The current data basically tells us that the vaccine works to protect people against Ebola," says Dr. Bertrand Draguez, medical director of Médecins Sans Frontières, which took part in the research along with WHO and authorities in Guinea. (wuft.org)
In the immediate vaccination group, there were no cases of Ebola virus disease with symptom onset at least 10 days after randomization," the researchers say, "whereas in the delayed vaccination group there were 16 cases of Ebola virus disease from seven clusters, showing a vaccine efficacy of 100 percent. (wuft.org)
The first person to receive the trial vaccine in Guinea was Mohamed Soumah, 27. (wuft.org)
In the VSV-EBOV investigational vaccine, the gene for the outer protein of VSV replaces the same gene segment of the Zaire Ebola virus species. (wuft.org)
Here, we delineate potential prototype species that encompass the breadth of clinical outcomes of a given family, have existing reverse genetics tools or animal disease models, and can be amenable to a platform approach to vaccine testing. (bvsalud.org)
Trials of one of the most promising candidate Ebola vaccines are to begin swiftly in healthy volunteers in Europe, Gabon and Kenya, as funds from the Wellcome Trust enable an international consortium to accelerate development of the VSV Ebola vaccine, rVSV-EBOV. (wellcome.org)
In one of many international meetings at the World Health Organization (WHO) in Geneva last week it was agreed that the rapid development and deployment of an effective vaccine is now an urgent priority. (wellcome.org)
Eight hundred vials of the vaccine, which was developed by the Public Health Agency of Canada, have been donated by the Canadian Government to be used in these trials. (wellcome.org)
The National Institutes of Health (NIH) have also announced that concurrent early-phase trials of the vaccine have begun in the USA. (wellcome.org)
Now, accelerated vaccine development is being properly prioritised too, so we have the best possible chance of a safe and effective vaccine in time to transform our prospects of containing Ebola. (wellcome.org)
The vaccine can therefore generate an immune response to Ebola infection but does not cause a vaccinated individual to become infected with Ebola. (wellcome.org)
Unfortunately, influenza vaccine composition needs to be updated annually due to antigenic shift and drift in the viral immunogen hemagglutinin (HA). (mdpi.com)
Chumakov KM, Powers LB, Noonan KE, Roninson IB, Levenbook IS (1991) Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine. (springer.com)
Although no licensed Ebolavirus vaccines are currently available, vaccine research in non-human primates, the 'gold standard' animal model for Ebolavirus, has produced several promising candidates. (biomedcentral.com)
This Phase II study was part of this accelerated program, evaluating the safety and immunogenicity of the 2-dose vaccine regimen in healthy and HIV-infected African adults, with 28-, 56-, and 84-day intervals between doses. (plos.org)
We conducted a randomised trial to assess the safety and the immunogenicity of the Ad26.ZEBOV, MVA-BN-Filo vaccine regimen in 3 different vaccination intervals in healthy and HIV-infected adults. (plos.org)
When a mutated form of the virus was discovered a few years ago, the veterinary community thought they had found the "magic bullet" that would lead them to a vaccine that would prevent the neurologic disease. (horsesport.com)
However, a vaccine will ultimately be an important tool in the prevention effort. (homelandsecuritynewswire.com)
The launch of Phase 1 Ebola vaccine studies is the first step in a long process. (homelandsecuritynewswire.com)
During Phase 1 studies, researchers test an investigational vaccine in a small group of people to evaluate its safety and the immune response it provokes. (homelandsecuritynewswire.com)
The NIAID / GSK Ebola vaccine candidate is based on a type of chimpanzee cold virus, called chimp adenovirus type 3 (ChAd3). (homelandsecuritynewswire.com)
Rather, the Ebola gene that it carries allows the cells of the vaccine recipient to express a single Ebola protein, and that protein prompts an immune response in the individual. (homelandsecuritynewswire.com)
It is important to know that the Ebola genetic material contained in the investigational vaccine cannot cause a vaccinated individual to become infected with Ebola. (homelandsecuritynewswire.com)
The experimental NIAID / GSK vaccine performed extremely well in protecting nonhuman primates from Ebola infection," Fauci noted. (homelandsecuritynewswire.com)
The release notes that the candidate vaccine builds upon three earlier NIAID -developed investigational Ebola vaccines that began Phase 1 clinical trial testing in 2003. (homelandsecuritynewswire.com)
As part of the VRC 207 trial, NIAID will also test a version of the NIAID / GSK vaccine that contains genetic material from only the Zaire Ebola species. (homelandsecuritynewswire.com)
In parallel, NIH has partnered with an international consortium that includes the British-based Wellcome Trust, as well as Britain's Medical Research Council and Department for International Development to test the same NIAID / GSK monovalent vaccine candidate. (homelandsecuritynewswire.com)

Earlier this year, it showed positive results in clinical trials at the Walter Reed Army Institute of Research and the National Institute of Allergy and Infectious Diseases. (wuft.org)
Ebola disease can be confused with other more common infectious diseases such as malaria, typhoid fever, meningococcemia, and other bacterial infections. (cdc.gov)
Due to these nonspecific symptoms, particularly early in the course of the disease, Ebola disease can be confused with other more common infectious diseases such as malaria . (cdc.gov)
Mandate of the department is to teach pathology of disease progression and practical training for identification of gross lesions, histopathological, microscopic and clinical post mortem examinations for diagnosis of diseases in animals. (arawaliveterinarycollege.com)
Pathogenesis, gross and microscopic pathology of mycoplasma infection (contagious bovine pleuropneumonia, contagious caprine pleuropneumonia, porcine enzootic pneumonia), diseases of chlamydial group, Q-fever, anaplasmosis and ehrlichiosis. (arawaliveterinarycollege.com)
This pathogenic fungus causes a wide spectrum of diseases, including the mucosal infection oropharyngeal candidiasis (OPC) which frequently effects patients with human immunodeficiency virus (HIV). (bepress.com)
In Uganda, we focus on vector-borne diseases including Crimean-Congo hemorrhagic fever and Rift Valley fever. (nih.gov)
Virus diseases caused by the HERPESVIRIDAE. (lookformedical.com)
A general term for diseases produced by viruses. (lookformedical.com)
Vesicular diseases in swine are identical clinically. (wikisource.org)
The importance of vesicular diseases in today's world-trade environment remains high. (wikisource.org)
Because FMD is extremely contagious and has such a dramatic economic impact, vesicular diseases must be properly diagnosed, reported, and controlled. (wikisource.org)
The characteristics of the viruses that cause vesicular diseases are shown in Table 25.2 . (wikisource.org)
The Jackson Lab researched how viruses elicit plant diseases, and devised mechanisms for disease control in transgenic plants. (berkeley.edu)
Our research goals were to understand how viruses elicit plant diseases and to devise mechanisms for disease control in transgenic plants. (berkeley.edu)
Bacterial infections are the most important infectious diseases. (turmericforhealth.com)
In the past decade, new diseases such as West Nile virus and vesicular stomatitis have caused their share of damage and anxiety in the horse world. (horsesport.com)
The diseases that become reportable are usually extremely deadly, can be spread among multiple species, or have a significant impact on agriculture. (horsesport.com)
I am interested in disease causing vectors especially those causing Neglected Tropical Diseases (NTDs) such as Zika, While Nile Virus, Yellow fever, Nyakungzuwa, Dengue (all caused by Mosquito) and the Tsetse Fly causing sleeping sickness and other diseases. (gnatwork.ac.uk)
She worked in collaboration with researchers at the VRC , the U.S. Army Medical Research Institute of Infectious Diseases , and Okairos , a Swiss-Italian biotechnology company acquired by GSK in 2013. (homelandsecuritynewswire.com)
His research interests include bacterial infections in animals and humans, methicillin-resistant staphylococcal infections, Clostridium difficile , antimicrobial resistance, emerging infectious diseases, infection control. (equimanagement.com)
Easley talks about how much has changed in equine dentistry , the wide variety of dental diseases horses can have, the need for a good dental exam with the right tools, the use of radiographs, and what horse owners expect today in equine dental care. (equimanagement.com)
In Canada, confirmatory testing for FMD is done at the CFIA 's National Centre for Foreign Animal Diseases in Winnipeg. (canada.ca)
Additional diseases that are commonly seen from this virus also include Orchid Fleck Virus (OFV) and Coffee Ringspot Virus (CRV) . (plantsentry.com)
The two most common diseases associated with this viral genus is the Mirafiori Lettuce Big-Vein virus (MLBVV) and the Lettuce Big-Vein associated Virus (LBVaV). (plantsentry.com)
None of the tibroviruses, except for Bas-Congo virus, have been associated with any diseases. (wikimili.com)
CLASSIFICATION OF DISEASES AND INJURIES I. INFECTIOUS AND PARASITIC DISEASES (001-139) Includes: diseases generally recognized as communicable or transmissible as well as a few diseases of unknown but possibly infectious origin Excludes: acute respiratory infections (460-466) influenza (487. (cdc.gov)
certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
It is provided as an additional code where it is desired to identify the bacterial agent in diseases classified elsewhere. (cdc.gov)
Many conditions can cause oral erythema, including localized trauma, infection, contact allergy, cancer, and other causes of inflammatory changes, as well as systemic diseases such as those that produce vesiculoerosive lesions or oral ulceration. (medscape.com)
In the United States, requirements for reporting diseases are mandated by state laws or regulations, and the list of reportable diseases in each state differs. (cdc.gov)
This report provides updated uniform criteria * for state health department personnel to use when reporting the nationally notifiable infectious diseases listed in Part 1 of this report. (cdc.gov)
In October 1990, in collaboration with CSTE, CDC published Case Definitions for Public Health Surveillance (4), which, for the first time, provided uniform criteria for reporting cases to increase the specificity of reporting and improve the comparability of diseases reported from different geographic areas. (cdc.gov)
Data for nationally notifiable diseases reported by the 50 states, New York City, the District of Columbia, and the U.S. territories are collated and published weekly in the Morbidity and Mortality Weekly Report (MMWR). (cdc.gov)

Humans can be infected with the virus and experience flu-like symptoms and occasionally oral blisters and lymphadenopathy in the neck. (wikipedia.org)
Rift Valley fever virus (RVFV) is an emerging mosquito-transmitted virus that circulates in livestock and humans in Africa and the Middle East. (bvsalud.org)
Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD) in humans, with a case fatality rate ranging from 23 to 90%, depending on the outbreak [ 1 ]. (biomedcentral.com)
The family , known as filoviruses, contains several viruses that are known to cause hemorrhagic, often lethal disease in humans and nonhuman primates (NHPs) all of which are within the Marburgvirus or Ebolavirus genera. (biomedcentral.com)
Cuevavirus, Striavirus, and Thamnovirus are not known to cause disease in humans or NHPs. (biomedcentral.com)
Candida albicans is the most prevalent human fungal pathogen, found as a commensal organism in the mucosa, gastrointestinal, and urogenital tracts of humans. (bepress.com)
The type species of LYMPHOCRYPTOVIRUS, subfamily GAMMAHERPESVIRINAE , infecting B-cells in humans. (lookformedical.com)
Vaccination by direct injection of lentiviral vector was more effective in sterile alpha motif and HD-domain containing protein 1-knockout (SAMHD1-knockout) mice, suggesting that lentiviral vectors containing Vpx, a lentiviral protein that increases the efficiency of dendritic cell transduction by inducing the degradation of SAMHD1, would be an effective strategy for the treatment of chronic disease in humans. (jci.org)
The application of whole-genome sequencing showed that the virus was acquired from humans. (justbalancinghealth.com)
The virus in farmed mink has a different genomic composition compared to that in humans, chiefly a deletion of 69/70 in the N-terminal domain of the spike protein, and a combination of Y453F in the RBD, with I692V, M1229I, and S1147L in various parts of the spike protein. (justbalancinghealth.com)
Ebolaviruses are known for their ability to cause devastating viral hemorrhagic fever outbreaks in humans and great apes, but the natural reservoir for EBOV has remained elusive for many years. (biomedcentral.com)
EBOV was discovered in humans during two concurrent outbreaks in 1976. (biomedcentral.com)
In 2007 to 2008 a large outbreak of viral hemorrhagic fever with a case-fatality rate of approximately 25% occurred in humans in Uganda. (biomedcentral.com)
The human Sp110 gene is a member of the nuclear body (NB) components that functions as a nuclear hormone receptor transcriptional coactivator and plays an important role in immunoprotective mechanisms against pathogens in humans. (biomedcentral.com)
The disease is not known to affect humans or other species of livestock. (ca.gov)
he virus is not transmissible to humans. (ca.gov)
The disease can also affect many other species of animals and has occurred in sheep, goats, wildlife and occasionally humans. (ca.gov)
They inhibit the growth of infections caused by different microbes in humans and are likely to use the same mechanism of action in microbial infections in dogs too. (turmericforhealth.com)
1] Animal experimentation is going on all over the world the genes from chicken, cows, rats and humans have been engineered into commercial fish species in order to increase the growth rates- GM salmon, for instance, have been engineered to reach six times their natural size. (jesus-is-savior.com)
FMD is an animal disease and not related to a disease in humans caused by the Coxsackie virus called Hand, Foot and Mouth disease. (canada.ca)
What makes these virus families so unique is their ability to infect humans, animals, and plants. (plantsentry.com)
Out of the 20 genera that exist in this viral family there are 2 that are most commonly known to humans worldwide. (plantsentry.com)
But, in the countries of India and Africa, this virus remains a serious threat to humans. (plantsentry.com)
Similarly, direct injection of viruses into the cerebrospinal fluid (e.g., via lumbar puncture in humans) also permits targeting of the peripheral (PNS) and central nervous systems (CNS). (frontiersin.org)
[8] No anti-CPV antibodies have ever been detected in humans and no disease has been associated with CPV. (wikimili.com)
TIBV infection of humans has not been reported. (wikimili.com)
SARS-CoV-2 is highly pathogenic in humans and is classified as a biosafety level (BSL)-3 pathogen, which makes manipulating it relatively difficult due to its infectious nature. (biomedcentral.com)

A combination of DNA vaccination and a recombinant adenovirus serotype 5 boost resulted in cross-protective immunity in non-human primates. (biomedcentral.com)
His work carried out in the field of Dengue virus brings together such families of science as Serotype and Flavivirus. (research.com)

Given the significant roles of viral and host factors during infection, characterization of these interactions is critical for therapeutic targeting with neutralizing antibodies and vaccines. (bvsalud.org)
Without field efficacy studies, researchers must rely on animal models of MARV infection to assess the efficacy of vaccines and treatments, with the limitations being the accuracy of the animal model in recapitulating human pathogenesis. (biomedcentral.com)
Overall, our research activities are targeted towards a better understanding of virus biology and virus-induced host responses to foster the development of vaccines and therapeutics. (nih.gov)
DMT's general work philosophy/strategy combines areas such as 'molecular biology', 'tissue culture', 'immunology' and 'animal models' with the goal to develop vaccines and therapeutics for emerging zoonotic viruses, the mission of the Laboratory of Virology, Division of Intramural Research (DIR) and NIAID. (nih.gov)
This is the latest of several international commitments to fast-track early tests of candidate Ebola vaccines so they could be available for trial in West Africa by the end of the year, and if successful deployed more widely in 2015. (wellcome.org)
VSV is a pathogen found in livestock and has been used successfully in making other vaccines. (wellcome.org)
Given the severity of the situation in West Africa, trials of several candidate vaccines are being simultaneously fast-tracked through a global collaborative effort. (wellcome.org)
Lentiviral vector-based dendritic cell vaccines induce protective T cell responses against viral infection and cancer in animal models. (jci.org)
These properties have made lentiviral vectors advantageous for use in dendritic cell (DC) vaccines. (jci.org)
There are a number of alternate vaccination strategies in current development which may circumvent the need for annual re-vaccination, including new platform technologies such as viral-vectored vaccines. (mdpi.com)
We discuss the different vectored vaccines that have been or are currently in clinical trials, with a forward-looking focus on immunogens that may be protective against seasonal and pandemic influenza infection, in the context of viral-vectored vaccines. (mdpi.com)
In light of the severity of Ebolavirus disease and the observed increase in Ebolavirus outbreaks over the past decade, the expedited translation of potential candidate therapeutics and vaccines from bench to bedside is currently the most challenging task for the field. (biomedcentral.com)
Tried and true public health interventions, strong supportive medical care and the rapid testing of Ebola vaccines and antiviral treatments can help to reduce suffering now and in the future," said CDC director Thomas R. Frieden. (homelandsecuritynewswire.com)
Phase 2 clinical trials of investigational vaccines are designed to further assess safety and immune response in larger numbers of volunteers. (homelandsecuritynewswire.com)
There are vaccines and antibodies to combat the virus, but don't be fooled! (plantsentry.com)

Thus, this study identifies another important function for the evolutionarily conserved Toll pathway, in addition to its well-studied roles in embryonic dorso-ventral patterning and innate immunity. (sdbonline.org)
There are four structural viral proteins, of which VP1 has been shown to elicit protective immunity in cattle ( Bachrach 1977 ). (wikisource.org)
The S protein is also important for induction of protective humoral and cellular immunity during infection. (biomedcentral.com)
This infection tends to be more serious in neonates owing to their lack of immunity, lack of lymphoid tissue in the conjunctiva, and absence of tears at birth. (medscape.com)

Monoclonal antibodies to murine hepatitis virus-4 (strain JHM) define the viral glycoprotein responsible for attachment and cell-cell fusion. (microbiologyresearch.org)
Neuronal cell surface molecules mediate specific binding to rabies virus glycoprotein expressed by a recombinant baculovirus on the surfaces of lepidopteran cells. (harvard.edu)
The existence of specific rabies virus (RV) glycoprotein (G) binding sites on the surfaces of neuroblastoma cells is demonstrated. (harvard.edu)
E) Rhabdoviral pseudotypes bearing the indicated S protein variants (equipped with a C-terminal HA-epitope tag) or no viral glycoprotein were subjected to SDS-PAGE under reducing conditions and immunoblot in order to investigate S protein processing and particle incorporation. (justbalancinghealth.com)
Virus particles also contain a matrix protein that coils the nucleocapsid and a surface glycoprotein that spans the viral envelope to associate with the matrix protein and the nucleocapsid core. (berkeley.edu)
Anti-Ebola virus glycoprotein (EBOV GP) binding and neutralising antibodies were measured at baseline and at predefined time points throughout the study. (plos.org)
The genome encodes for the typical five proteins found in all rhabdoviruses: nucleocapsid (N), phosphoprotein (P), matrix (M), glycoprotein (G), and polymerase (L). However, there are three additional genes, U1-U3, that encode for proteins of unknown function. (wikimili.com)
His study in SFTS virus is interdisciplinary in nature, drawing from both Serine, Bioinformatics, Syncytium, Glycoprotein and Arginine. (research.com)

In a development that could change the way the deadly Ebola disease is fought, researchers have announced promising results of a new vaccine's trial in Guinea, one of several countries affected by a historic outbreak in West Africa. (wuft.org)
Patients with fatal disease usually develop more severe clinical signs early during infection and die typically between days 6 and 16 of complications including multiorgan failure and septic shock (mean of 7.5 days from symptom onset to death during the 2014-2016 outbreak in West Africa). (cdc.gov)
Rift Valley fever virus (RVFV) is an emerging arbovirus found in Africa. (bvsalud.org)
Following its discovery, MARV cases were sporadically identified in Africa. (biomedcentral.com)
Almost 5,000 people - all but a few from within West Africa - are known to have died in the unrelenting Ebola outbreak, and the actual toll is likely to be much higher. (wellcome.org)
Communities in West Africa continue to suffer from the crisis with remarkable fortitude and finally the rich world has committed significant finance and resources to support critical public health measures, and progress in the search for treatments is encouraging. (wellcome.org)
A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. (lookformedical.com)
Ebolavirus is endemic in Central Africa and the Philippines. (biomedcentral.com)
The Zaire species of the virus is responsible for the current Ebola outbreak in West Africa. (homelandsecuritynewswire.com)

If malaria is considered for a suspect Ebola patient, follow the Guidance for Malaria Diagnosis in Patients with Suspect Ebolavirus Infection in the United States , as diagnostics should be done promptly and treatment instituted immediately if malaria is diagnosed. (cdc.gov)
Typhoid fever , meningococcemia , and other bacterial infections (for example, pneumonia ) also have similar nonspecific symptoms and can be confused with Ebola. (cdc.gov)
Although generally less well known than its cousin Ebola virus (EBOV), MARV was the first filovirus discovered following outbreaks in Germany and Yugoslavia (now Serbia) in 1967 [ 7 ]. (biomedcentral.com)
The gene for the outer protein of the VSV virus is replaced with a segment of the gene for the outer protein of the Zaire Ebola virus species. (wellcome.org)
We investigated safety, tolerability, and immunogenicity of the heterologous 2-dose Ebola vaccination regimen in healthy and HIV-infected adults with different intervals between Ebola vaccinations. (plos.org)
Today we know the best way to prevent the spread of Ebola infection is through public health measures, including good infection control practices, isolation, contact tracing, quarantine, and provision of personal protective equipment," added Fauci. (homelandsecuritynewswire.com)
The adenovirus is used as a carrier, or vector, to deliver segments of genetic material derived from two Ebola virus species: Zaire Ebola and Sudan Ebola. (homelandsecuritynewswire.com)
Masayuki Saijo studied Antibody and Nucleoprotein that intersect with Ebola virus. (research.com)

VSV-EBOV is based in part on a genetically engineered version of vesicular stomatitis virus, which primarily affects rodents, cattle, swine and horses. (wuft.org)
A recent report suggested that 2 novel bunyaviruses discovered in insects in Côte d'Ivoire caused lethal disease in swine in South Korea. (cdc.gov)
recently reported that, in 2013, GOLV and HEBV caused prevalent and lethal infections in swine in South Korea ( 9 ). (cdc.gov)
GOLV was isolated from swine serum in porcine kidney 15 cells. (cdc.gov)
We also tested 108 serum samples collected in 2011 from mosquito-exposed swine in Kumasi, Ghana, where mosquitoes were found to be infected with HEBV ( 6 ) and GOLV (S. Junglen, unpub. (cdc.gov)
They can be caused by infection with the viruses of foot-andmouth disease (FMD), vesicular stomatitis (VS), vesicular exanthema of swine (VES), and swine vesicular disease (SVD). (wikisource.org)
VS was recognized in horses and cattle in the United States during World War I ( Cotton 1927 ), but infection in swine was not reported until 1943 ( Schoening 1943 ). (wikisource.org)
Vesicular stomatitis (VS) is a virus caused disease that primarily affects cattle, horses and swine. (ca.gov)
Swine contribute more to airborne transmission because they excrete very large quantities of virus compared to other species. (canada.ca)

Research directed at select prototype pathogens is part of the approach put forth by the National Institute of Allergy and Infectious Disease (NIAID) to prepare for future pandemics caused by emerging viruses. (bvsalud.org)
Sociodemographic characteristics, symptoms of SARS-CoV-2 infection (assessed with the Centers for Disease Control and Prevention [CDC] Person Under Investigation Symptom List), and symptoms of post-infectious syndromes (ie, fatigue, sleep quality, muscle/joint pains, unrefreshing sleep, and dizziness/fainting, assessed with CDC Short Symptom Screener for myalgic encephalomyelitis/chronic fatigue syndrome) were assessed at baseline and 3 months via electronic surveys sent via text or email. (cdc.gov)
The platform was developed to counteract emerging neglected viral pathogens with low worldwide infectious disease impact but of significant local/regional public health concern utilizing the concept of emergency immunization in the form of ring vaccination. (nih.gov)
The mechanism by which latent viruses, such as genetically transmitted tumor viruses ( PROVIRUSES ) or PROPHAGES of lysogenic bacteria, are induced to replicate and then released as infectious viruses. (lookformedical.com)
Virus shedding is an important means of vertical transmission (INFECTIOUS DISEASE TRANSMISSION, VERTICAL). (lookformedical.com)
One antibody (2.25.4) effectively neutralized all infectious virus. (microbiologyresearch.org)
As the infected cancer cells are destroyed by oncolysis , they release new infectious virus particles or virions to help destroy the remaining tumour. (privacytools.io)
The Equine Infectious Anemia (EIA) virus belongs to the family Retroviridae. (ca.gov)
Because EHV-1 is so common, the idea of screening animals for latent infection, such as is done with the Coggins test for equine infectious anaemia, is impractical. (horsesport.com)
The Severe fever with thrombocytopenia syndrome study combines topics in areas such as Infectious disease, Disease and Phlebovirus. (research.com)
Chemical conjunctivitis is becoming less common owing to the use of erythromycin ointment or povidone iodide in place of silver nitrate solution for the prophylaxis of infectious conjunctivitis. (medscape.com)
Bacterial and viral infections are major causes of septic neonatal conjunctivitis, with Chlamydia being the most common infectious agent and Neisseria being the most visually threatening. (medscape.com)
Although several noninfectious and infectious agents can inflame the conjunctiva, the most common causes of neonatal conjunctivitis are silver nitrate solution and chlamydial, gonococcal, staphylococcal, and herpetic infections. (medscape.com)
Case definitions for some infectious conditions not designated as nationally notifiable are included in Part 2 of this report. (cdc.gov)

E. coli -induced increases in blood-brain barrier permeability and inflammatory neutrophilic infiltration were also inhibited [ 5876 ], suggesting that the C 60 compound could be a useful therapeutic agent in some cases of bacterial meningitis [ 738 ]. (nanomedicine.com)
The most common infections include bacterial infection affecting the skin and digestive tract. (turmericforhealth.com)
Other common bacterial infections include Streptococcal, Actinmycosis and Leptospirosis infections. (turmericforhealth.com)
Few bacterial infections that affect the digestive system include Campylobacter, Helicobacter, Salmonella infection. (turmericforhealth.com)
Leptospirosis is a bacterial infection that affects the dog's entire system. (turmericforhealth.com)
Research demonstrates that turmeric and curcumin has anti-bacterial activity against Clostridium species. (turmericforhealth.com)
These properties of turmeric can aid in fighting various bacterial infection in dogs. (turmericforhealth.com)
Turmeric's anti-bacterial activity is efficacious in inhibiting various bacterial infection like Staph infection, H.pylori infection, Leptospirosis and Clostridium. (turmericforhealth.com)
Ulcers may appear as single or multiple lesions, and they are easily distinguished from primary or secondary viral infections, bacterial infections (eg, necrotizing ulcerative gingivitis), dermatologic conditions (lichen planus, cicatricial pemphigoid, pemphigus), and traumatic injuries (contusions, lacerations, burns) by the healthy appearance of adjacent tissues and the lack of distinguishing systemic features. (medscape.com)
Secondary bacterial infection, PFAPA syndrome, primary viral infection, or rheumatologic disorder may cause fever. (medscape.com)
This category will also be used in primary coding to classify bacterial infections of unspecified nature or site. (cdc.gov)

It is well known as a vector of the vesicular stomatitis virus, which causes the disease vesicular stomatitis in animals, particularly livestock. (wikipedia.org)
These results suggest the discovery of disease caused by these 2 novel viruses in a major livestock species. (cdc.gov)
Outbreaks lead to high rates of miscarriages in domesticated livestock. (bvsalud.org)
In addition, we have included selected livestock species (i.e. pig, sheep and goat) and unconventional animal species such as reservoir species (i.e. rodents and bats). (nih.gov)
CDFA, along with the California Department of Health Services, monitors cases in livestock. (ca.gov)
If an outbreak of FMD occurred, the virus could spread rapidly throughout Canada, due to routine livestock movements. (canada.ca)

The expelling of virus particles from the body. (lookformedical.com)
The researchers used SARS-CoV-2 spike-expressing vesicular stomatitis virus particles. (justbalancinghealth.com)
Vesicular stomatitis virus (VSV) pseudo particles (pp) had been coated with ancestral and mutant S proteins. (healthitizer.com)

In 2010, an alfalfa plant located in Stadl-Paura, Austria displayed symptoms of viral infection. (plantsentry.com)
The neutralization antibody test (NT) for serum using live SARS-CoV-2 is a method in which inhibition of the serum upon viral infection is observed in the presence of neutralizing antibodies against proteins involved in viral binding and penetration in the serum. (biomedcentral.com)

One well-studied vesicular stomatitis virus enzootic involving this fly is on Ossabaw Island off the coast of Georgia in the United States. (wikipedia.org)

A genus of the family HERPESVIRIDAE, subfamily ALPHAHERPESVIRINAE, consisting of herpes simplex-like viruses. (lookformedical.com)
[7] A number of viruses including adenovirus , reovirus , measles , herpes simplex , Newcastle disease virus , and vaccinia have been clinically tested as oncolytic agents. (privacytools.io)
[12] In 2015, talimogene laherparepvec (OncoVex, T-VEC), an oncolytic herpes virus which is a modified herpes simplex virus, became the first oncolytic virus to be approved for use in the United States and the European Union , for the treatment of advanced inoperable melanoma . (privacytools.io)
Herpes simplex virus (HSV) was one of the first viruses to be adapted to attack cancer cells selectively, because it was well understood, easy to manipulate and relatively harmless in its natural state (merely causing cold sores ) so likely to pose fewer risks. (privacytools.io)
Equine Herpes Virus-1 (EHV-1) infection in horses can cause respiratory disease, abortion in mares, neonatal foal death and neurological disease. (ca.gov)
For more information see our Equine Herpes Virus webpage. (ca.gov)
Curcumin and its derivative inhibit the growth of herpes simplex virus suggesting that it may show inhibitory activity against the canine herpes virus. (turmericforhealth.com)
They are not related to herpes simplex infections and do not present as or develop into vesicular lesions. (medscape.com)
Herpes simplex viruses (human herpesviruses types 1 and 2) commonly cause recurrent infection affecting the skin, mouth, lips, eyes, and genitals. (msdmanuals.com)
оперізувальний герпес Herpes zoster is infection that results when varicella-zoster virus reactivates from its latent state in a posterior dorsal root ganglion. (msdmanuals.com)
His work on Thymidine kinase, Herpes simplex virus and Mononegavirales as part of general Virus study is frequently connected to Coronavirus, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. (research.com)
The most common viral oral infections include primary herpetic gingivostomatitis, recurrent intraoral herpes simplex virus (HSV) infection, recurrent herpes labialis, primary herpes varicella, and herpangina. (medscape.com)
Viral infections are typically self-limiting, but more serious complications can cause difficulties with recovery (eg, herpes simplex encephalitis, viral meningitis). (medscape.com)
Educate pregnant women on the importance of regular examinations to detect and treat sexually transmitted infections such as herpes simplex, gonorrhea, and chlamydia in order to decrease the incidence of neonatal conjunctivitis. (medscape.com)

Virus-induced immune complex disease: identification of specific viral antigens and antibodies deposited in complexes during chronic lymphocytic choriomeningitis virus infection. (microbiologyresearch.org)
Protein structure of lymphocytic choriomeningitis virus: identification of the virus structural and cell associated polypeptides. (microbiologyresearch.org)
Monoclonal antibodies to lymphocytic choriomeningitis virus react with pathogenic arenaviruses. (microbiologyresearch.org)
Monoclonal antibodies to lymphocytic choriomeningitis virus and Pichinde viruses: generation, characterization and cross-reactivity with other arenaviruses. (microbiologyresearch.org)
Injection of a lentiviral vector encoding an MHC class I-restricted T cell epitope of lymphocytic choriomeningitis virus (LCMV) and CD40 ligand induced an antigen-specific cytolytic CD8 + T lymphocyte response that protected the mice from infection. (jci.org)

Monoclonal antibodies prepared against Tacaribe and Junin viruses have been used to define further the serological relationships between arenaviruses of the Tacaribe complex. (microbiologyresearch.org)
The kinetics of reaction between antibody and virus were examined for all five neutralizing antibodies. (microbiologyresearch.org)
Variants of Tacaribe virus resistant to neutralization by antibody 2.25.4 were obtained by growth in the presence of this antibody and neutralization kinetics were reexamined using the heterologous monoclonal neutralizing antibodies. (microbiologyresearch.org)
Several different neutralization profiles were obtained, suggesting that point mutations resulted in conformational changes at topographically selected distinct epitopes recognized by the remaining antibodies. (microbiologyresearch.org)
Molecular studies of LCM virus-induced immunopathology: development and characterization of monoclonal antibodies to LCM virus. (microbiologyresearch.org)
The current study sought to show whether the Y453F mutation causes changes in the spike protein expression, altered binding to the host cell receptor, and susceptibility to neutralizing antibodies. (justbalancinghealth.com)
Anti-BAV antibodies have been detected in a variety of animals, including cattle, throughout Florida and the Caribbean. (wikimili.com)
In conclusion, the CRNT for COVID-19 is a convenient assay system that can be performed in a BSL-2 laboratory with high specificity and sensitivity for evaluating the occurrence of neutralizing antibodies against SARS-CoV-2. (biomedcentral.com)
Measuring the SARS-CoV-2 neutralizing antibodies is important for proper diagnosis, to study the serological epidemiology and determine infection control of SARS-CoV-2. (biomedcentral.com)

Blocking this site inhibits the virus from bonding to the host cell. (bio-itworld.com)
Carboxyfullerene directly inhibits in vitro growth of Streptococcus pyogenes and enhances bactericidal activity of neutrophils in mice in vivo [ 5874 ], suggesting that the fullerene derivative "can be considered an antimicrobial agent for group A streptococcus infection. (nanomedicine.com)
Inosine monophosphate dehydrogenase (IMPDH) enzyme is responsible for formation of genetic material in viruses and curcumin inhibits the activity of this enzyme. (turmericforhealth.com)
Curcumin inhibits infectivity of various enveloped viruses such as pseudorabies virus. (turmericforhealth.com)
Animal studies show that curcumin reduces gastric inflammation and inhibits the growth of H.pylori infection. (turmericforhealth.com)

Neither virus encodes NS proteins, nor do the viruses infect vertebrate cells or cause disease in mice that have been intracerebrally inoculated with the viruses ( 5 - 7 ). (cdc.gov)
The animal rhabdoviruses replicate in the cytoplasm and the best studied example, vesicular stomatitis virus (VSV), encodes five proteins. (berkeley.edu)

a) outbreak occurrence data inclusive of geo-location, host species, number of animals affected and onset date, b) ecological data analysis c) biotic and abiotic variables inclusive of animal density, hydrological features and streams, elevation and surface water properties, air temperature and precipitation, vegetation ENSO (El Nino Southern Oscilation) data, soil properties and long term trends in environmental variables. (usda.gov)
However, in 1999 an outbreak was identified in the Democratic Republic of Congo, where multiple spillover events into the human population are thought to have taken place over the course of 2 years. (biomedcentral.com)
Outbreaks have continued to pop up since 2005, with a 2007 outbreak in Uganda, two instances in 2008 that involved tourists visiting Uganda returning home to the United States and Netherlands with MVD, and outbreaks in Uganda in 2012, 2014, and 2017 [ 1 ]. (biomedcentral.com)
A £3.1m (US $5m) grant from the Wellcome Trust will allow several global partners, overseen by the WHO, to gather essential safety data for rVSV-EBOV, which had been tested only in monkeys before this outbreak. (wellcome.org)
Researchers from Harvard , Yale , and Emory compared the estimated excess deaths in New York during the peak of the 1918 influenza pandemic with above-average deaths during the early period of the COVID-19 outbreak in a new research letter published in JAMA Network Open. (bio-itworld.com)
During the peak of the 1918 H1N1 influenza outbreak in New York City, a total of 31,589 all-cause deaths occurred among 5,500,000 residents, yielding an incident rate of 287.17 deaths per 100,000 person-months. (bio-itworld.com)
During the early period of the COVID-19 outbreak in New York City, 33,465 all-cause deaths occurred among 8,280,000 residents, yielding an incident rate of 202.08 deaths per 100,000 person-months. (bio-itworld.com)
In the absence of any failsafe prevention, the burden is on owners, show organizers and veterinarians to make responsible decisions when moving horses around, and when an outbreak takes place in or near their own back yards. (horsesport.com)
Multiple factors contribute to every outbreak, which makes it very difficult to identify a single factor in any situation. (horsesport.com)
The concepts of his Virus study are interwoven with issues in Recombinant DNA, Molecular biology, Outbreak and Virulence. (research.com)

The ABSL3/4 areas of our research facility are suited for work with most rodent species, ferrets, and nonhuman primates (NHPs). (nih.gov)

The female can transmit the virus to its offspring via its ovaries, so the juvenile flies can emerge already carrying the pathogen. (wikipedia.org)
The tick-borne intracellular pathogen, Anaplasma phagocytophilum (Rickettsiales: Anaplasmataceae) causes human granulocytic anaplasmosis after infection of polymorphonuclear leucocytes. (biomedcentral.com)

Buffered solutions containing C 60 and Semliki Forest virus (SFV, Togaviridae ) or vesicular stomatitis virus (VSV, Rhabdoviridae ), when illuminated with visible light for up to 5 hours, resulted in a significant loss of infectivity. (nanomedicine.com)
This week we'd like to take a closer look at the Rhabdoviridae virus family. (plantsentry.com)
The Rhabdoviridae virus family officially contains 20 genera and has 143(4) species that are negative-sense and consist of a single-strand RNA. (plantsentry.com)
Tibrovirus is a poorly characterized genus of viruses in the family Rhabdoviridae , order Mononegavirales . (wikimili.com)

Influenza-virus-mediated disease can be associated with high levels of morbidity and mortality, particularly in younger children and older adults. (mdpi.com)
Vaccination is the primary intervention used to curb influenza virus infection, and the WHO recommends immunization for at-risk individuals to mitigate disease. (mdpi.com)

1. Ascertain the viral ecology of disease and factors mediating the emergence of VSV, including the characterizing epidemiological factors associated with the maintenance of disease in endemic versus non-endemic settings (ABADRU) and (FADRU), determining the environmental conditions that influence vector dominance in endemic versus non-endemic settings, and identifying environmental-vector interactions responsible for the emergence of viral infections in new geographical locations. (usda.gov)
Ecology studies in the sw US will be expanded to include endemic areas in Mexico and environmental-vector interactions responsible for the emergence of viral infections in new geographical locations. (usda.gov)
In this study, we tested whether preventative and therapeutic vaccination could be achieved by direct injection of antigen-expressing lentiviral vector, obviating the need for ex vivo transduction of dendritic cells. (jci.org)
Injected lentiviral vector preferentially transduced splenic dendritic cells and resulted in long-term expression. (jci.org)
The injection of chronically infected mice with a lentiviral vector encoding LCMV MHC class I and II T cell epitopes and a soluble programmed cell death 1 microbody rapidly cleared the virus. (jci.org)
Being a senior level scientific professional specialized for vector control, I worked upon the different aspect of Entomological work and successfully leading the Department of Vector Biology & Control for more than 30 years with following achievements in my research career. (gnatwork.ac.uk)
I worked on different aspect of Entomological work and successfully leading the Department of Vector Biology & Control for more than 30 years with following achievements in my research career. (gnatwork.ac.uk)
Taking experience from Kala-azar control at Vaishali district (with cases less than 1/10000 per population in year 2016), at present I am actively engaged in developing Zero-Tolerance Kala-azar zone by implementing improved strategies of vector control at 2 more districts(s) viz. (gnatwork.ac.uk)
Alphacypermethrine on Kala-azar vector to get it registration to CIB Delhi, Optimising the implementation of synthetic pyrethroid insecticide in IRS for VL elimination, development of insecticide quantification kits for IRS evaluation, rotation of insecticide for resistance management etc. (gnatwork.ac.uk)
BHV, BAV, SWBV and TIBV were isolated from biting midges, suggesting that midges are the major arthropod vector for these viruses. (wikimili.com)

The public process was "short circuited" because CNF did not include verbiage that banned llamas in their draft Chugach National Forest Land Management Plan that was open for public comment in 2018. (alaskallamas.com)
In 2018 and 2019 the virally infected plants have been evaluated by scientists and have identified a new novel Nucleorhabdovirus strain. (plantsentry.com)

Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may reveal novel therapeutic targets and inform our understanding of coronavirus disease 2019 (COVID-19) pathogenesis. (interchim.com)
DMT also operates field sites in Mali (since 2010) and more recently in Uganda (2019) funded through the International Centers for Excellence in Research (ICER), NIAID. (nih.gov)
The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is thought to be a disease originally occurring in animals but transmitted across the species barrier to human beings, probably through an intermediate host. (justbalancinghealth.com)
Please send your comments in objection to the Chugach National Forest Land Management Plan during the 60 day objection period ending October 28, 2019. (alaskallamas.com)
[11] the approval was withdrawn in 2019. (privacytools.io)
SARS-CoV-2 is a novel coronavirus that emerged in 2019 and is now classified in the genus Coronavirus with closely related SARS-CoV. (biomedcentral.com)

2020), Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection, Cell, 184, 1-16. (interchim.com)
A team from Yale conducted a retrospective cohort study of 1827 patients with confirmed COVID‐19 who were hospitalized within the Yale‐New Haven Health System (YNHHS) between March 14, 2020 and April 23, 2020 and published their findings in Hepatology . (bio-itworld.com)
An online national survey of 4, 351 adolescents and young adults aged 13-24 years was conducted in May 2020 and used to assess relationships among COVID-19 and e-cigarettes and cigarettes. (bio-itworld.com)
The first case of SARS-CoV-2 infection in farmed mink on a Dutch farm was identified in April 2020. (justbalancinghealth.com)
Disease Du Jour is brought to you in 2020 by Merck Animal Health . (equimanagement.com)

An oncolytic adenovirus , a genetically modified adenovirus named H101 , was approved in China in 2005 for the treatment of head and neck cancer. (privacytools.io)
Unlike non-viral tracers, which have many limitations, genetically modified viruses can target specific cell types. (2bscientific.com)

We also show that small-molecule antagonists of identified gene products inhibited SARS-CoV-2 infection in monkey and human cells, demonstrating the conserved role of these genetic hits across species. (interchim.com)

The disease in cattle and pigs is impossible to distinguish from foot-and-mouth disease. (wikipedia.org)
The fly feeds on feral Ossabaw Island Hogs and spreads the virus widely, though clinical disease is rare. (wikipedia.org)
Infection can cause systemic disease, including encephalitis or hemorrhagic fevers. (cdc.gov)
Bleeding is not universally present but can manifest later in the course of disease as petechiae, ecchymosis/bruising, or oozing from venipuncture sites, mucosal hemorrhage, or blood in stool or vomitus. (cdc.gov)
The biological significance of Lrp1, including its role in hepatic disease in vivo, however, remains to be determined. (bvsalud.org)
4. Establish research program on Crimean Congo Hemorrhagic Fever (CCHF) and Nipah Virus Disease (NiVD), including development of detection and diagnostic in vectors and hosts as well as studying mechanisms of inter-species transmission. (usda.gov)
These analyses will be used to identify ecological variables associated with VS disease occupancy and spread in the western U.S. and to develop predictive models for disease spread. (usda.gov)
This review will compare various animal models to the available descriptions of human pathogenesis and aims to evaluate their effectiveness in modeling important aspects of Marburg virus disease. (biomedcentral.com)
METHODS: We conducted a prospective cohort study comparing adults with SARS-CoV-2 infection (coronavirus disease-positive [COVID+]) with adults who tested negative (COVID-), enrolled within 28 days of a Food and Drug Administration (FDA)-approved SARS-CoV-2 test result for active symptoms. (cdc.gov)
CONTEXT: The Centers for Disease Control and Prevention (CDC) has a long history of using high-quality science to drive public health action that has improved the health, safety, and well-being of people in the United States and globally. (cdc.gov)
Although many medically important Candida species are commensal to the gut or colonizers of the skin, these organisms have the propensity to cause disease in the event of a waning immune system. (bepress.com)
The 'Disease Modeling and Transmission' (DMT) Section was established in August 2008 and conducts innovative research on viral pathogens requiring high or maximum containment. (nih.gov)
His postdoctoral research was conducted in the field of virology (filoviruses and hantaviruses) at the Institute of Virology in Marburg and the Centers for Disease Control and Prevention in Atlanta, USA ('National Research Council' fellowship). (nih.gov)
Differentially regulated interferon response determines the outcome of Newcastle disease virus infection in normal and tumor cell lines. (microbe.tv)
In Italy in 1546, Fracastorius made what is probably the first report of a vesicular disease ( Bulloch 1927 ). (wikisource.org)
Airaksinen A, Pariente N, Menendez-Arias L, Domingo E (2003) Curing of foot-and-mouth disease virus from persistently infected cellsby ribavirin involves enhanced mutagenesis. (springer.com)
Borrego B, Novella IS, Giralt E, Andreu D, Domingo E (1993) Distinct repertoire of antigenic variants of foot-and-mouth disease virus in the presence or absence of immune selection. (springer.com)
Since its discovery in 1976, Ebolavirus has caused periodic outbreaks of viral hemorrhagic fever associated with severe and often fatal disease. (biomedcentral.com)
Since CNF's ban identifies pack llamas as a disease threat, this opens the door to eliminate them for all uses (including recreational) in the future. (alaskallamas.com)
The California Department of Food and Agriculture, Animal Health Branch (AHB) plays a significant role in protecting California's equine population through equine disease surveillance, regulatory disease control and prevention programs. (ca.gov)
In the U.S., Screwworm is a Foreign Animal Disease reportable within 24 hours of diagnosis. (ca.gov)
These data supported the approval by the European Union for prophylaxis against EBOV disease in adults and children ≥1 year of age. (plos.org)
According to an EHV-1 Consensus Statement prepared by the American College of Veterinary Internal Medicine in 2009, EHV-1 'is ubiquitous in most horse populations throughout the world, and causes disease in horses and extensive economic losses through frequent outbreaks of respiratory disease, abortion, neonatal foal death, and myeloencephalopathy. (horsesport.com)
It turns out some viruses that didn't have the DNA mutation were also causing the neurological disease, though it's more likely with the DNA mutation. (horsesport.com)
The ACVIM Consensus Report admits that there is very limited knowledge of the disease in many respects. (horsesport.com)
Adding to the problem is the fact that EHV-1 is not a reportable disease in Canada or the US, (although it has been made a reportable disease in some individual states), which means the government cannot prevent the movement of horses that have been exposed or even infected. (horsesport.com)
Cipaglucosidase alfa (ATB200) is a novel recombinant human acid alpha-glucosidase (GAA) investigated for the treatment of patients with Pompe disease, a rare inherited metabolic disorder characterized by a deficiency in GAA. (drugbank.com)
Under certain circumstances, the vaccine's ability to prevent infection or disease (called efficacy) can be determined in a Phase 2 trial. (homelandsecuritynewswire.com)
The disease is currently present in many areas of the world. (canada.ca)
This disease causes a significant yield reduction in citrus orchards. (plantsentry.com)
Virus-mediated gene therapy has the potential to deliver exogenous genetic material into specific cell types to promote survival and counteract disease. (frontiersin.org)
[7] There is no evidence of human infection or any disease associated with BAV. (wikimili.com)
TIBV is an orphan virus and not associated with any disease. (wikimili.com)
The IVI fulfills the requirements of the EU Minimum Biorisk Management Standards for Laboratories Working with Foot-And-Mouth Disease Virus. (unog.ch)
For purposes of this discussion, which involves therapy for oral erythematous lesions, the presented conditions are arbitrarily divided into the following categories: local infection, contact allergy, oral cancer, and localized vesiculoerosive and ulcerative disease. (medscape.com)
This article focuses on dental management of oral erythema, but, in cases of systemic disease, a more comprehensive medical approach to therapy is necessary. (medscape.com)
The general rationale for dental treatment of oral erythematous lesions is to relieve symptoms, to prevent problems that arise from the disease (eg, secondary infection, tissue morbidity), and to support the patient's general health. (medscape.com)
In cases involving severe disease or worsening symptoms in the face of initial intervention, medical referral and comanagement should be recommended, with patient follow-up by appointment or phone to prevent potential systemic complications or morbidity due to patient noncompliance or other patient reasons for a lack of follow-up. (medscape.com)

2. The characterization of VSV transmission in endemic vs non-endemic settings will be conducted in collaboration with Mexico's SENASICA-EADC laboratory to conduct genomic sequencing and phylogeographic characterization of viral strains collected through VS surveillance activities in Mexico and to identify the ecological and environmental factors associated with the occurrence of VSV in Mexico. (usda.gov)
Arias A, Lázaro E, Escarmís C, Domingo E (2001) Molecular intermediates of fitness gain of an RNA virus: characterization of a mutant spectrum by biological and molecular cloning. (springer.com)
Morphometric characterization of TAMs in human colorectal liver metastases captures individual populations, corresponding to single-cell clusters and associated with distinct clinical outcome and transcriptional profiles. (rupress.org)

The large number of horses moving around to horse shows is indisputably doing its share in causing outbreaks. (horsesport.com)
She discussed diarrhea in adult horses and foals . (equimanagement.com)

Collectively, these observations suggest that highly conserved LDL family proteins may play a significant role in facilitating entry of viruses from several distinct families. (bvsalud.org)
Proteins found in any species of virus. (lookformedical.com)
These proteins have been implicated in control of viral transcription and may possibly serve as the "glue" that binds the nucleocapsid to the appropriate membrane site during viral budding from the host cell. (lookformedical.com)
Several features of lentiviral vectors have made them advantageous for the expression of therapeutic proteins in vivo. (jci.org)
Endogenous synthesis of antigen results in efficient proteolytic peptide processing and presentation of peptide antigen on MHC class I proteins. (jci.org)
Automated quantitation assays of VSVpp an infection of Caco-2 cells revealed that mutant S proteins had related however various an infection kinetics that regularly decreased effectivity. (healthitizer.com)
To circumvent the need for BSL-3 laboratories, an alternative assay was developed that avoids live virus and instead uses a recombinant VSV expressing luciferase and possesses the full length or truncated spike proteins of SARS-CoV-2. (biomedcentral.com)

Clinical manifestations of infections with Candida species can range from superficial mucosal infections to deep organ involvement usually resulting from haematogenous spread of infection. (bepress.com)

The equine industry plays a critical role in the economic infrastructure of California, therefore its protection is a top priority within the Department. (ca.gov)
The AHB is a national leader in addressing situations which threaten the health of the equine industry. (ca.gov)
What precautions do vets/staff in equine hospitals need to take? (equimanagement.com)
Episode 19 - Duncan Peters , DVM, DACVSMR, Certified ISELP Member and co-owner of East-West Equine Sports Medicine in Lexington, Kentucky, talks about equine tendon and ligament injuries and treatments . (equimanagement.com)
Episode 17 - Robert Holland , DVM PhD, who is in private practice in Kentucky, talks about equine strangles. (equimanagement.com)
Episode 15 - Raul Bras , Raul Bras, DVM, CJF (Certified Journeyman Farrier), a shareholder in Rood and Riddle Equine Hospital in Lexington, Kentucky, talks about veterinarian-farrier relationships . (equimanagement.com)
Bras' professional focus is on equine podiatry, and he travels from his home base in Lexington throughout the country and the world. (equimanagement.com)
Episode 13 - Michele L. Frazer , DVM, DACVIM, DACVECC, is an Associate veterinarian at Hagyard Equine Medical Institute in Lexington, Kentucky. (equimanagement.com)

Patients with a history of major recurrent aphthous ulcers (canker sores) often have residual scarring in the oral mucosa from previous lesions. (medscape.com)
Stomatitis may involve swelling and redness of the oral mucosa or discrete, painful ulcers (single or multiple). (msdmanuals.com)

C Sixty's anti-HIV fullerene compound CSDF1 exhibits high water solubility (200 gm/liter), complete renal excretion, and a highly nontoxic LD50 of 800 mg/kg in rodents [ 4630 , 5235 ]. (nanomedicine.com)

For a complete description of each condition discussed in this article, including etiology, epidemiology, signs and symptoms, and diagnosis, the reader is encouraged to assess the published literature. (medscape.com)

3 mm in diameter), tightly clustered lesions. (medscape.com)
Confusion may arise if the lesions coalesce into a large lesion resembling major aphthous stomatitis. (medscape.com)
These viruses generate symptoms of localized lesions on leaves, stems, and fruits of plants that have high economical value. (plantsentry.com)
Localized infection is a common cause of erythematous and ulcerative oral lesions. (medscape.com)
Treatment of HSV-1 infection should include assurance, information, caution regarding infectivity (eg, avoiding nail biting to reduce herpetic whitlow and/or touching of the lesions and then the eye to prevent corneal infection, oral sexual activity that might transmit the infection), and supportive care. (medscape.com)

Delayed and/or inadequate innate immune responses can result in failure to combat pathogens, whereas excessive and/or inappropriate responses cause runaway inflammation. (sdbonline.org)
however, the function of glycans of host organisms in innate immune responses is less well known. (sdbonline.org)
In senju mutants, reduced expression of galactose-containing glycans resulted in hyperactivation of the Toll signaling pathway in the absence of immune challenges. (sdbonline.org)
Interestingly, Toll activation in immune-challenged wild type (WT) flies reduced the expression of galactose-containing glycans. (sdbonline.org)
however, Toll activation in response to infection leads to degalactosylation, which raises the immune response to an adequate level and contributes to the prompt elimination of pathogens. (sdbonline.org)
Engineering oncolytic measles virus to circumvent the intracellular innate immune response. (microbe.tv)
A defect in COPI transport due to mutant COPA causes multimerization of STING on the Golgi and type I interferon-driven immune dysregulation in mice. (rupress.org)
[1] [2] Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host anti-tumour immune system responses. (privacytools.io)
Cryptococcosis is a fungal infection that affects dogs especially when they have a weakened immune system. (turmericforhealth.com)

Extensive laboratory experience and mild nature of aerosol laboratory infections justifies Level 2. (cdc.gov)
Necropsy: Introduction, objectives, pre-necropsy guidelines, procedure for post mortem examination of various species of animals including wild animals, post mortem changes, collection, preservation and dispatch of specimens (morbid materials) for laboratory examination, writing of post mortem report, veterolegal necropsy , veterolegal wounds. (arawaliveterinarycollege.com)
In the laboratory, A. phagocytophilum can be propagated in undifferentiated human promyelocytic HL-60 cells. (biomedcentral.com)

I hope that this movie and future movies will help increase public engagement in virology. (microbe.tv)
I also taught a Graduate Plant Virology (a three unit course), Co-Instructed Plant Biotechnology (a three unit upper division course), and offered a Freshman Seminar course, "Viruses, Health and Society" that enrolled a maximum of 15 talented entering freshman. (berkeley.edu)
For several years, I also have taught a six week Comparative Virology for graduate students at China Agricultural University in Beijing, and a one-month long graduate level Plant Virology minicourse at Zhejiang University in Hangzhou. (berkeley.edu)
In Knipe DM, Howley PM (eds) Fields virology. (springer.com)
The scientist's investigation covers issues in Virology, Virus, Antibody, Vero cell and Immunoglobulin G. His work carried out in the field of Virology brings together such families of science as Monoclonal antibody, Recombinant DNA and Antigen. (research.com)
Masayuki Saijo spends much of his time researching Virology, Virus, Severe fever with thrombocytopenia syndrome, Antibody and SFTS virus. (research.com)
Masayuki Saijo focuses on Virology, Virus, Severe fever with thrombocytopenia syndrome, SFTS virus and Severe fever with thrombocytopenia syndrome virus. (research.com)
His main research concerns Virology, Severe fever with thrombocytopenia syndrome, SFTS virus, Virus and Severe fever with thrombocytopenia syndrome virus. (research.com)

Rift Valley Fever Virus (RVFV) is a negative sense segmented RNA virus that can cause severe hemorrhagic fever. (bvsalud.org)
BACKGROUND: Long-term symptoms following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are a major concern, yet their prevalence is poorly understood. (cdc.gov)
Bas-Congo virus (BASV) was discovered in 2009 in the Democratic Republic of Congo in a blood sample collected from a 32-year-old male who survived a severe illness resembling hemorrhagic fever. (wikimili.com)
Oral inflammation and ulcers, known as stomatitis, may be mild and localized or severe and widespread. (msdmanuals.com)
Common severe infections include encephalitis. (msdmanuals.com)
Masayuki Saijo interconnects Viral entry, Tick and Microbiology in the investigation of issues within Severe fever with thrombocytopenia syndrome virus. (research.com)
Masayuki Saijo has included themes like Leukocytopenia, Phlebovirus, Lipid bilayer fusion and Viral hemorrhagic fever in his Severe fever with thrombocytopenia syndrome study. (research.com)
Severe purulent discharge and eyelid edema in a newborn with gonococcal conjunctivitis (confirmed with Gram stain and culture). (medscape.com)
Events over the past 15 years have resulted in the promulgation of regulations in the United States to enhance biosecurity by restricting the access to pathogens and toxins (i.e., biological select agents and toxins [BSATs]), which pose a severe threat to human being, animal, or plant health or to animal or plant products, to qualified institutions, laboratories, and scientists. (cdc.gov)

Because Lrp1 has a high expression level in hepatocytes, we developed a mouse model in which Lrp1 is specifically deleted in hepatocytes to test how the absence of liver Lrp1 expression affects RVF pathogenesis. (bvsalud.org)

Côte d'Ivoire ebolavirus (CIEBOV) was discovered during an epizootic (animal epidemic) in chimpanzees in the Taï National Park in Côte d'Ivoire in 1994, in the first confirmed introduction of an EBOV into a great ape population [ 13 ]. (biomedcentral.com)

Here we performed genome-wide CRISPR screens in Vero-E6 cells with SARS-CoV-2, Middle East respiratory syndrome CoV (MERS-CoV), bat CoV HKU5 expressing the SARS-CoV-1 spike, and vesicular stomatitis virus (VSV) expressing the SARS-CoV-2 spike. (interchim.com)
Staphylococcal infections can also affect the upper respiratory tract of dogs. (turmericforhealth.com)
Environmental factors expose dogs to fungal infections which enter the body through the skin or respiratory tract. (turmericforhealth.com)
In a current examine posted to the bioRxiv * preprint server, researchers investigated the affect of amino acid (AA) substitutions of extreme acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron on spike (S) protein operate, processing, and neutralization susceptibility. (healthitizer.com)

The bite of the female fly transmits the vesicular stomatitis virus in mammals. (wikipedia.org)

The research objectives are to study the viral lifecycle and the virus-induced host responses to identify targets of intervention and to develop measures of prevention. (nih.gov)
Well from my field I can confirm that a whole series of studies, cited below, have shown defective type I IFN responses in cancer cells such as ovarian cancer cells. (microbe.tv)
Each of the viruses engages in unique host associations during infection, and each virus gene has multiple roles in pathogenesis and mediates different host responses. (berkeley.edu)
Anamnestic responses were observed in all healthy participants receiving Ad26.ZEBOV as booster at 1 year after the first dose. (plos.org)

Following intravenous administration at 15 mg/kg of body weight, pharmacokinetic studies showed a half-life of 6.8 hours in the blood with distribution into the tissues. (nanomedicine.com)
Sp110 expression is induced in human peripheral blood leukocytes and spleen but not in other tissues [ 8 ]. (biomedcentral.com)
The pathology of neonatal conjunctivitis is influenced by the anatomy of the conjunctival tissues in the newborn. (medscape.com)

Despite significant progress made in the management of patients with fungal infections, the emergence of antifungal resistant clinical isolates creates significant problem in regards to antifungal prophylaxis and empirical treatment strategies. (bepress.com)

In this approach, a patient's monocytes are obtained by leukapheresis and then differentiated ex vivo to immature DCs. (jci.org)
These data are consistent with in vivo results: an avirulent RV mutant bearing the same double mutation is not able to infect sensory neurons or motoneurons (P. Coulon, J.-P. Ternaux, A. Flamand, and C. Tuffereau, J. Virol. (harvard.edu)
Our data strongly suggest that these specific attachment sites on neuroblastoma cells represent a neuronal receptor(s) used by RV to infect certain types of neurons in vivo. (harvard.edu)
Coffin JM (1995) HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. (springer.com)
In vitro and in vivo experiments have shown that Ebolavirus pathogenicity is multifactorial, including viral and host determinants. (biomedcentral.com)

Members of both genera of viruses encode a nonstructural (NS) protein that suppresses the antiviral interferon response of the vertebrate host ( 3 , 4 ). (cdc.gov)
Our recent studies identified a scavenger receptor, LDL receptor related protein 1 (Lrp1), as a potential pro-viral host factor for RVFV and related viruses, including Oropouche virus (OROV) infection. (bvsalud.org)
The low-density lipoprotein receptor-related protein 1 (Lrp1) is a recently identified host factor for cellular entry and infection by RVFV. (bvsalud.org)
New insights into the SARS-CoV-2 spike protein, a daily aerosol protectant, a look a death rates in 1918 and now, and a journal dedicated to publishing COVID-19 research with visible peer review. (bio-itworld.com)
The positively charged site allows strong bonding between the virus protein and the negatively charged human-cell receptors. (bio-itworld.com)
The study compared 316 transfused patients to controls and preliminary analysis showed a significant reduction in mortality within 28 days, specifically in patients transfused within 72 h of admission with plasma with an anti-spike protein receptor binding domain titer of ≥1:1350. (bio-itworld.com)
Viral inactivation was oxygen-dependent and equally efficient in solutions containing protein. (nanomedicine.com)
Viral RNA polymerase, a nonstructural protein, has been termed "virus infection associated antigen" (VIAA) for diagnostic purposes but is more accurately termed "FMDV nonstructural protein 3D. (wikisource.org)
The third was spike protein bearing the mutations found in SARS-CoV-2 isolated from infected mink. (justbalancinghealth.com)
The researchers found that all the mutations in the mink variant allowed the virus to incorporate and process the spike protein at the novel furin cleavage site, at the interface between the S1/S2 subunits of the spike. (justbalancinghealth.com)
B) Summary of mink-specific S protein mutations found in human and mink SARS-CoV-2 isolates. (justbalancinghealth.com)
C) Location of the mink-specific S protein mutations in the context of the 3-dimensional structure of the S protein. (justbalancinghealth.com)
Leptospirosis infection activates a protein named nuclear factor-kappaB which plays an essential role in inflammation and research proves that curcumin can attenuate this activity and prevent it from damaging kidney tissue. (turmericforhealth.com)
In sum, the substitutions T19I, D24-26, T376A, S375F, and Q954H decreased the infectivity of VSVpp by affecting the S protein processing. (healthitizer.com)

Age at onset should be noted because major recurrent aphthous ulcers (canker sores) begin after puberty, and herpetiform ulcers are uncommon in children. (medscape.com)
Major recurrent aphthous ulcers (canker sores) can be 1-3 cm in diameter. (medscape.com)

Nuclear antigens encoded by VIRAL GENES found in HUMAN HERPESVIRUS 4. (lookformedical.com)
B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma . (lookformedical.com)
Antigens of Pichinde virus. (microbiologyresearch.org)

This genus of viruses is commonly spread through arthropod vectors such as aphids, leafhoppers, and planthoppers. (plantsentry.com)
This genus of viruses is transmitted commonly by leafhoppers, planthoppers, and aphids but can also be spread through vegetation propagation and mechanical measures. (plantsentry.com)
This genus naturally occurs in two families of plants: Compositae (which largely contain Angiosperms or flowering plants) and Solanaceae (which contain nightshade or potato family of flowering plants). (plantsentry.com)

The author does not elaborate further, but it occurs to me that this reproductive modality allows for mechanisms for genetic recombination distinctly different from that seen in sexual reproduction. (microbe.tv)
Deoxyribonucleic acid that makes up the genetic material of viruses. (lookformedical.com)
Viruses whose genetic material is RNA. (lookformedical.com)
They employ a range of genetic, developmental, and neurobiological tools in zebrafish to understand what the heart tells the brain, and how critical internal sensory systems adjust homeostatic and somatic behaviors, including social interactions. (harvard.edu)
Molecular genetic approaches and cytological studies used to follow infection processes are providing new information about the mechanisms of interactions with host cellular components during infection. (berkeley.edu)
Curcumin exerts anti-viral effect againstCoxsackievirus by interfering in the activity of its genetic material and preventing it from replicating. (turmericforhealth.com)
Curcumin exerts anti-viral effect by interfering in its genetic mechanism and reducing infectivity of enveloped viruses. (turmericforhealth.com)
Scientists are creating unthinkable genetic modifications in our food, mixing animal, insects and even human DNA into animals and plants, and the reason of course is the giant biotechnology corporations are desperate for profits at any cost. (jesus-is-savior.com)
The biotech industry wants it all kept quiet as they push products onto the market with unprecedented speed to recoup their billions of dollars in accumulated genetic research and investment costs. (jesus-is-savior.com)
Crucially, some viral vectors (i.e., viruses specifically used to deliver genetic material into cells) have the potential to circumvent the blood-brain- (BBB) and blood-spinal cord barriers (BSCB) when intravenously injected. (frontiersin.org)
method to introduce genetic material into select neuronal populations is by virus administration into muscle, which is the focus of this review. (frontiersin.org)

Because cell culture experiments may not show the full host range of a specific virus, we tested serum samples collected in 2008 from Sus scrofa domestica pigs in Gouléako, the rural village where GOLV and HEBV were first isolated from mosquitoes in Côte d'Ivoire ( 5 , 6 ). (cdc.gov)
As reported in a new paper, now available on the preprint server bioRxiv, experiments using live virus show that the molecule is among the most potent SARS-CoV-2 antivirals yet discovered. (bio-itworld.com)
2] Some of these experiments with salmon are being carried out very close to us in New Zealand in fact. (jesus-is-savior.com)

The ability of a pathogenic virus to lie dormant within a cell (latent infection). (lookformedical.com)
A secondary form of the condition involves reactivation of latent virus residing in the sensory ganglion of the trigeminal nerve. (medscape.com)

Protection of guinea pigs inoculated with Tacaribe virus against lethal doses of Junin virus. (microbiologyresearch.org)
On the contrary, current evidence indicates that mutant spectra contribute to viral pathogenesis, can modulate the expression of phenotypic traits by subpopulations of viruses, can include memory genomes that reflect the past evolutionary history of the viral lineage, and, furthermore, can participate in viral extinction through lethal mutagenesis. (springer.com)

Emerging Microbes and Infections. (utmb.edu)
Dogs are exposed to the environment and hence susceptible to a variety of infections from different microbes. (turmericforhealth.com)

However, this method takes a long time because it depends on the growth of the virus, and it is not a simple measuring system in terms of complicated handling and biosafety for highly pathogenic SARS-CoV-2. (biomedcentral.com)
Recent events have changed the manner in which scientists acquire and work with pathogenic microorganisms and biological toxins (Morse and Weirich, 2011 ). (cdc.gov)

Veterinary Clinical Pathology: Introduction, Haematology - Different anticoagulant used in haematology, interpretation of blood tests (haemoglobin, packed cell volume, total erythrocyte count, erythrocytic indices, erythrocytic sedimentation rate, total leukocyte count, absolute count of different leucocytes), blood smear examination and its interpretation. (arawaliveterinarycollege.com)
The research team is in active discussions with commercial partners to ramp up manufacturing and clinical testing of AeroNabs. (bio-itworld.com)
[8] Most current oncolytic viruses are engineered for tumour selectivity, although there are naturally occurring examples such as reovirus and the senecavirus , [9] resulting in clinical trials . (privacytools.io)
Phase 1 clinical trials are the first step in what is typically a multi-stage clinical trials process . (homelandsecuritynewswire.com)
Participants in both groups will be seen and evaluated by clinical staff nine times over a 48-week period. (homelandsecuritynewswire.com)
This portion of the Phase 1 safety study, which will also involve twenty healthy adults, is expected to begin in October at the NIH Clinical Center and potentially another U.S. location. (homelandsecuritynewswire.com)

This group of viruses includes human immunodeficiency virus (HIV), the immunodeficiency viruses of apes and monkeys (SIV), goats (CAEV), cats (FIV) and cattle (BIV). (ca.gov)
[11] TIBV appears to be widespread among cattle in Australia. (wikimili.com)
Experimental infections of cattle produced viremia, but no observable signs of illness. (wikimili.com)

During the initial phase of infection, these processes are orchestrated by the first HAdV gene expressed during infection, early region 1A (E1A). (bepress.com)
Any of the processes by which cytoplasmic factors influence the differential control of gene action in viruses. (lookformedical.com)
However, SYNV differs from VSV by replicating in the nucleus and by encoding a sixth gene that is required for cell-to-cell movement of nucleocapsids. (berkeley.edu)
Yet once such fish escape from the farms in which they are produced, nothing can stop them from breeding with natural stock and passing their deformities into the gene pool. (jesus-is-savior.com)
Administration of gene therapy viruses into skeletal muscle, where distal terminals of motor and sensory neurons reside, has been shown to result in extensive transduction of cells within the spinal cord, brainstem, and sensory ganglia. (frontiersin.org)
In this review article, we outline key characteristics of major gene therapy viruses-adenovirus, adeno-associated virus (AAV), and lentivirus-and summarize the mechanisms regulating important steps in the virus journey from binding at peripheral nerve terminals to nuclear delivery. (frontiersin.org)
Gene therapy viruses are non-replicating, but still hijack host cell machinery to express transgenes of interest in the nucleus. (frontiersin.org)
His study looks at the relationship between Virus and topics such as Gene, which overlap with Thymidine kinase. (research.com)

investigate the role of C-type lectin Mincle in promoting cell death and acute kidney injury. (rupress.org)

Anatomy12

Organisms31

Diseases8

Chemicals and Drugs25

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Phenomena and Processes14

Information Science3

Health Care1

Geographicals3

Recombinant vesicular stomatitis5

Replication23

Vaccine27

Diseases34

Humans27

Serotype2

Vaccines15

Immunity4

Glycoprotein8

Africa9

Ebola8

Swine9

Infectious14

Bacterial11

Livestock6

Particles3

Viral infection2

Enzootic1

Herpes14

Lymphocytic chori5

Antibodies9

Inhibits5

Encodes2

Outbreak10

Nonhuman primates1

Pathogen2

Rhabdoviridae4

Influenza virus2

Vector10

20182

20196

20205

Genetically2

Inhibited SARS-CoV-2 infection1

Disease38

Characterization3

Horses2

Proteins7

Mucosal1

Equine8

Oral mucosa2

Rodents1

ETIOLOGY1

Lesions5

Immune9

Laboratory3

Virology8

Severe9

Affects1

Epizootic1

Respiratory4

Mammals1

Responses4

Tissues3

Fungal infections1

Vivo5

Protein14

Aphthous2

Antigens3

Genus3

Genetic11

Experiments3

Latent2

Lethal2

Microbes2

Pathogenic2

Clinical6

Cattle3

Gene8

Acute1