• Isolates were genetically by toxigenic C . diphtheriae but has been expanded in diverse, indicating circulation and local transmission of some countries to include all C . diphtheriae species com- several diphtheria sublineages. (cdc.gov)
  • It is otherwise called a diphtheroid or coryneform due to its close phylogenetic relationship with diphtheria causing bacterium Corynebacterium diphtheriae. (wikipedia.org)
  • Corynebacterium diphtheriae , the cause of diphtheria in humans. (wikidoc.org)
  • The genus contains the species Corynebacterium diphtheriae and the nondiphtherial corynebacteria, collectively referred to as diphtheroids. (medscape.com)
  • In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum . (medscape.com)
  • Five of the six culture-positive diphtheria cases reported in the United States since 1988 have been associated with importation of Corynebacterium diphtheriae, an organism believed to have become rare or to have disappeared from the United States. (cdc.gov)
  • Case series from Canada, consistent with global surveillance, have found that the disease burden is increasingly attributed to cutaneous, non-pseudomembranous respiratory and systemic disease from toxigenic and non-toxigenic strains of Corynebacterium diphtheriae and C. ulcerans Footnote 2 Footnote 3 Footnote 4 Footnote 5 Footnote 6 Footnote 7 Footnote 8 . (canada.ca)
  • Corynebacterium diphtheriae is responsible for both endemic and epidemic diphtheria. (who.int)
  • Corynebacterium diphtheriae est responsable à la fois de la diphtérie endémique et épidémique. (who.int)
  • Genomic epidemiology and strain taxonomy of Corynebacterium diphtheriae. (pasteur.fr)
  • Background Corynebacterium diphtheriae is highly transmissible and can cause large diphtheria outbreaks where vaccination coverage is insufficient. (pasteur.fr)
  • Results The cgMLST scheme showed high allele call rate in C. diphtheriae and the closely related species C. belfantii and C. rouxii. (pasteur.fr)
  • Respiratory diphtheria is a serious infection caused by toxigenic Corynebacterium diphtheriae, and disease transmission mainly occurs through respiratory droplets. (cdc.gov)
  • Here we utilized whole-genome sequencing (WGS) to characterize recovered isolates of C. diphtheriae and two co-circulating non-diphtheritic Corynebacterium (NDC) species - C. pseudodiphtheriticum and C. propinquum. (cdc.gov)
  • Corynebacterium striatum is an important causative agent of IE within the genus. (lu.se)
  • Corynebacterium striatum is a bacterium that is a member of the Corynebacterium genus. (wikipedia.org)
  • It has recently been recognised as an emerging pathogen although the genus of Corynebacterium is not usually considered to be pathogenic. (wikipedia.org)
  • Corynebacterium is a genus of Gram-positive , facultatively anaerobic , non- motile , rod-shaped actinobacteria . (wikidoc.org)
  • In the genus Corynebacterium , AmtR is a key component of the nitrogen regulatory system, and it belongs to the TetR family of transcription regulators. (frontiersin.org)
  • The Corynebacterium genus is comprised of multiple taxa of bacteria, and C. mastitidis differentiates itself due to its oxidative and lipophilic nature [1]. (kenyon.edu)
  • Comparisons between species found high similarity between C. mastitidis and other species in the genus Corynebacterium, and lower levels of relatedness between C. mastitidis and other coryneform taxa [4]. (kenyon.edu)
  • Phylogenetic analyses of the Corynebacterium genus were performed using house-keeping loci but also secreted protein loci from Cp 3/99-5. (gla.ac.uk)
  • Corynebacterium glutamicum is a Gram-positive and generally regarded as safe (GRAS) microorganism with less endotoxicity. (frontiersin.org)
  • Recently, some specific Gram-positive bacteria, including Mycobacterium tuberculosis and Corynebacterium glutamicum , were found to possess a novel cell wall structure consisting of an arabinogalactan layer covalently linked to the peptidoglycan layer, and a special outer membrane consisting of mycolic acids (mycomembrane) [ 19 ]. (nature.com)
  • Corynebacterium striatum (n = 11) was the most common IE causing pathogen followed by Corynebacterium jeikeium (n = 5). (lu.se)
  • Particularly in the context of human disease, Corynebacterium striatum is generally considered an opportunistic pathogenic, particularly in a nosocomial setting. (wikipedia.org)
  • Scientific papers dating back until approximately 1980 recount cases of commensal Corynebacterium striatum contaminating samples from sites of infections. (wikipedia.org)
  • A paper published in 1993 found that isolates of described Corynebacterium Stratum stored by the American Type Culture Collection and the National Collection of Type Cultures were in fact not that of Corynebacterium striatum, although the recorded sequences corresponded with other known isolates of the species. (wikipedia.org)
  • More recently Corynebacterium striatum was found to in fact be the cause of infection and disease, given the opportunity. (wikipedia.org)
  • Not long after, researchers began to propose the notion that Corynebacterium striatum was the cause of disease even in patients that did not meet such criteria. (wikipedia.org)
  • Comparison of variations in the Corynebacterium genome allow for specific identification of the Corynebacterium Striatum. (wikipedia.org)
  • Corynebacterium striatum is a gram-positive bacterium, meaning they have a thin external peptidoglycan cell wall structure. (wikipedia.org)
  • Devriese LA, Riegel P, Hommez J, Vaneechoutte M, de Baere T, Haesebrouck F. Identification of Corynebacterium glucuronolyticum strains from the urogenital tract of humans and pigs. (dsmz.de)
  • C. mastitidis was first proposed as a new species in 1997 when strains were isolated in pure culture from the milk of sheep with subclinical mastitis from different geographical regions of Spain [4]. (kenyon.edu)
  • The 14 strains were found to be 100% similar, indicating genealogical homogeneity of the species [4]. (kenyon.edu)
  • Human studies are finding abundant Corynebacterium DNA sequences in samples from healthy people's eyes, but some strains of Corynebacterium may also cause eye infections in the immunocompromised and the elderly and one study found that a strain of Corynebacterium mastitidis can be an opportunistic pathogen on human skin. (sciencedaily.com)
  • For this purpose, 5 different bacterial species (ATCC) or strains confirmed by WHO were selected and each laboratory randomly received 2 unknown samples for identification. (who.int)
  • Clinicians should remain plex infections irrespective of species, infection site, or aware of the risk for diphtheria and improve diagnostic toxigenicity, enabling broader disease monitoring. (cdc.gov)
  • Isolates were collected for species redetermination by matrix-assisted laser desorption ionization-time of flight and for antibiotic susceptibility testing using Etests. (lu.se)
  • 0001). Vancomycin was active towards all Corynebacterium isolates, whereas resistance towards penicillin G was common. (lu.se)
  • By analysing the largest collection of Corynebacterium glucuronolyticum ( C. glucuronolyticum ) isolates from a single centre thus far, we aimed to appraise a potential causal link between an infrequently isolated species and the urethritis syndrome in men. (em-consulte.com)
  • It is colonized by bacteria, including species like Propionibacterium and Staphylococcus and yeast e.g. (cosmeticsdesign.com)
  • Staphylococcus , Corynebacterium , by dietary habits as well as by the ed, the number of frequent genes and Propionibacterium [8]. (who.int)
  • Some species of Corynebacterium have sequenced genomes that range in size from 2.5 - 3 Mbp. (wikidoc.org)
  • Comparative genomics, both intra- and inter-species showed all the genomes to be highly homologous. (gla.ac.uk)
  • A catalogue of 178 reference bacterial birth, and the delivery type is the first core of species has been identified genomes distributed among different factor that has an impact. (who.int)
  • a) The micro-organism responsible is difficult to culture (e.g. many Mycoplasma species). (wikipedia.org)
  • Up until 1993 there had only been three documented cases of respiratory infections caused by the species. (wikipedia.org)
  • 2022), this species is an established human pathogen. (dsmz.de)
  • Corynebacterium glucuronolyticum in men with and without urethritis syndrome: An underrecognized pathogen or a bona fide commensal? (em-consulte.com)
  • Commission Implementing Regulation (EU) 2023/669 of 22 March 2023 concerning the authorisation of a preparation of endo-1,4-beta-xylanase produced by Komagataella phaffii DSM 33574 as a feed additive for all poultry species for fattening and all poultry species reared for laying and reared for breeding (holder of authorisation: BioResource, international, Inc. represented in the Union by Pen & Tec Consulting, S.L.U. (efta.int)
  • Some nondiphtheria species of Corynebacterium produce disease in specific animal species, and some of these are also human pathogens . (wikidoc.org)
  • Background: Corynebacterium species are often dismissed as contaminants in blood cultures, but they can also cause infective endocarditis (IE), which is a severe condition. (lu.se)
  • Methods: Cases of IE caused by Corynebacterium species were identified through the Swedish Registry of Infective Endocarditis. (lu.se)
  • Endocarditis caused by Corynebacterium spp. (wikidoc.org)
  • Bayesian analysis of house-keeping loci distinguished the bacteria to a species level. (gla.ac.uk)
  • Across all samples Enterobacter species were the most common gram negative bacteria found. (cdc.gov)
  • Each laboratory was sent 2 species of bacteria for identification. (who.int)
  • [ 1 ] More recently, Van den Velde and colleagues have suggested that species of corynebacteria would be more correctly identified based on their cellular fatty acid profiles (ie, for the C14 to C20 fatty acids). (medscape.com)
  • Partial 16S rRNA sequences of each strain were examined and compared to other species of Corynebacteria with high GC contents. (kenyon.edu)
  • Furthermore, other fungal or bacterial species emitting those compounds are displayed. (charite.de)
  • Her main research interests have been the study of Mur ligases from different bacterial species and the search for inhibitors of these enzymes. (degruyter.com)
  • For more than 30 years, his main research interests have been the functional and structural study of the enzymes of peptidoglycan biosynthesis, the determination of the structure of peptidoglycan from certain bacterial species, and the search for peptidoglycan biosynthesis inhibitors that could act as antibacterial agents. (degruyter.com)
  • To find out which bacterial species lived on the eyes of their mice, the researchers swabbed samples from the conjunctiva of their mice across a petri dish and waited to see what grew, but even so, they would have missed Corynebacterium mastitidis if not for luck. (sciencedaily.com)
  • Species identification recommended for any isolate thought to be causing human infection. (unboundmedicine.com)
  • Nigéria, en décembre 2022 et publie depuis lors des rapports mensuels. (who.int)
  • Further experiments established that the Corynebacterium could cause immune cells from the conjunctiva to release IL-17.Tears from mice with Corynebacterium living in their conjunctivae were more deadly to the pathogens Candida albicans and Pseudomonas, both of which can cause loss of vision when they infect the eye. (sciencedaily.com)
  • In IBG-1, we focus on employing the robust and established amino-acid producer Corynebacterium , the especially product-tolerant Pseudomonas group, and photosynthetic Rhodobacter species as production hosts. (fz-juelich.de)
  • NIH researchers reporting in the journal Immunity on July 11 found that Corynebacterium mastitidis dwells on the eyes of laboratory mice, and that mice with Corynebacterium could fend off invading pathogenic microbes better than mice without it. (sciencedaily.com)
  • Some species may be pathogenic. (bvsalud.org)
  • CDC is actively researching new laboratory methods to better identify and characterize other Bordetella and Corynebacterium species. (cdc.gov)
  • In the urethritis group, the species was more frequently found as a sole isolate ( p = 0.041) and after prior infection with Chlamydia trachomatis ( p = 0.025). (em-consulte.com)
  • however, inflammation as the result of a reaction to trauma, metabolic or hormonal processes, autoimmunity, and an infection with Corynebacterium kroppenstedtii have all been implicated. (karger.com)
  • DQ12-45-1b, to analyze the function of its MVs in heme-iron recycling and sharing between species. (nature.com)
  • Finally, we found that the heme carried in MVs is utilized by multiple species, and we further verified that membrane fusion efficiency and species evolutionary distance determine heme delivery. (nature.com)
  • Together, our findings strongly suggest that MVs act as a newly identified pathway for heme recycling, and represent a public good shared between phylogenetically closely related species. (nature.com)
  • Interestingly, this species has exceptional resistance to a range of environmental challenges which contributes to its persistence in clinical environment and on human skin. (nature.com)
  • The microbiome, the "other ge- species have no representative in nome" or "second genome" of the culture collections. (who.int)
  • The metabolic pathways of Corynebacterium have been further manipulated to produce L-Lysine and L-Threonine . (wikidoc.org)
  • Each individ- cluding immune cells, but also the was previously cal ed the gastroin- ual harbours hundreds of different metabolic and nervous systems), testinal flora or microflora, the more species, most of which have not and protecting against pathogens pragmatic term "microbiota" is now yet been cultured. (who.int)
  • Pathogens encountered rarely in this context may include Corynebacterium ureolyticus and nonfermenting gram negative bacilli. (medscape.com)
  • 2020. https://peds.unboundmedicine.com/pedscentral/view/Johns_Hopkins_ABX_Guide/540637/3.0/Corynebacterium_species. (unboundmedicine.com)