• antigens
  • Thus, we have used genetic techniques to demonstrate that LFA-3 may serve a role in CTL-target cell interactions at the target cell level, but is not a molecule absolutely required for human allospecific CTL recognition of HLA antigens expressed on mouse cells. (jimmunol.org)
  • The antibody producing cells did not survive long and the antigens that the antibodies targeted remained unknown. (wikipedia.org)
  • human
  • When LFA-3 and HLA-A2 are coexpressed on the mouse cell surface, anti-LFA-3 MAb interfered with specific recognition and lysis of these target cells by human CTL capable of lysing HLA-A2-expressing mouse transfectants. (jimmunol.org)
  • A significant contribution of the LFA-3 molecule to CTL reactivity was not observed, however, because the presence of LFA-3 did not restore recognition by CTL clones previously found incapable of lysing HLA-A2-expressing mouse transfectants, nor was it required by those human CTL that could lyse mouse cell transfectants. (jimmunol.org)
  • To assess which features of heterochromatin may be directly recruited by the expression and localization of the XIST RNA we have analyzed a mouse/human somatic cell hybrid in which expression of human and mouse XIST/Xist has been induced from the active X by demethylation. (nih.gov)
  • A-C) Shows the XIST/Xist expression in cell nuclei using RNA FISH probes for the human XIST RNA (green) and the mouse Xist RNA (red). (nih.gov)
  • The mouse/human hybrid cell line AHA-11aB1 retains only the human Xa , and a subclone was previously described that stably expressed human XIST after three rounds of demethylation with 5aza (AHA-A5-2b) . (nih.gov)
  • Malignant characteristics of somatic cell hybrids of normal human and malignant mouse cells. (jax.org)
  • CHO cells deficient for hypoxanthine:guanine phosphoribosyl transferase (HPRT) were fused with irradiated normal human fibroblasts and subjected to HAT selection. (biomedcentral.com)
  • P. A. Jones, J. S. Rhim, and H. Isaacs, The relationship between tumorigenicity, growth in agar and fibrinolytic activity in a line of human osteosarcoma cells. (springer.com)
  • E. J. Stanbridge, and J. Wilkinson, Analysis of malignancy in human cells: malignant and transformed phenotypes are under separate genetic control, Proc. (springer.com)
  • Larizza L., Tenchini M.L., Rampoldi E., De Carli L., Colombi M., Barlati S. (1983) Derepression and Modulation of Plasminogen Activator in Human Cell Hybrids and Their Segregants. (springer.com)
  • In 1973 he described, with Edward Cohen, a method of producing antibodies involving human-mouse hybrid cells, or hybridomas. (wikipedia.org)
  • They fused "mouse myeloma cells secreting immunoglobulin of known specificity and human peripheral blood lymphocytes not secreting detectable immunoglobulin. (wikipedia.org)
  • The hybrid cells continued secretion of mouse immunoglobulin and initiate synthesis and secretion of human immunoglobulin. (wikipedia.org)
  • 2005). "In the search of potential human islet stem cells: is tetranectin showing us the way? (wikipedia.org)
  • hamster
  • This was accomplished by fusing daunorubicin-resistant myeloblast cells obtained from a patient with monosomy 7 leukemia to a daunorubicin-sensitive Chinese hamster cell line. (aacrjournals.org)
  • lymphocyte
  • Messner RP, Lindstrom FD, Williams RC Jr: Peripheral blood lymphocyte cell surface markers during the course of systemic lupus erythematosus. (springer.com)
  • protein
  • Marian Blanca Ramírez from the CSIC in Spain has been studying the effects of LRRK2, a protein associated with Parkinson's disease, on cell motility. (biologists.org)
  • Oct4-green fluorescent protein (GFP) transgenes that do not contain the proximal enhancer (PE) region are widely used to visualize reprogramming of the somatic to the pluripotent cell state. (biomedsearch.com)
  • differentiation
  • This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dendritic and T cells during inflammatory and immunological responses. (wikipedia.org)
  • biology
  • We are now accepting submissions for our upcoming special issue on 'Reconstituting cell biology', guest edited by Manuel Théry. (biologists.org)
  • herpes simpl
  • Campadelli-Fiume primarily researches Herpes Simplex Virus (HSV), particularly how HSV enters, assembles, and exits the cell during an active infection. (wikipedia.org)
  • HSV entry into the cell Viral assembly in cell HSV exit out of the cell Viral induced alteration of exocytic pathway Herpes Simplex Virus (HSV,herpes) consists of two types: Herpes simplex virus 1 (HSV-1) *Transmitted by oral contact, causes orolabial herpes (cold sores) and genital herpes *HSV-1 is the most common infection through the world. (wikipedia.org)
  • Proc
  • R. Pollack, R. Risser, S. Conlon, and D. Rifkin, Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40, Proc. (springer.com)
  • bind
  • Other studies indicated that peptides bind A11 in delivery to the cell surface for CTL screening, but fall off, and are destroyed intracellularly. (wikipedia.org)
  • antibody
  • A defect of immunoregulatory T cell subsets in systemic lupus erythematosus patients demonstrated with anti-2H4 antibody. (springer.com)